Template:PBB/5327

Plasminogen activator, tissue
PDB rendering based on 1a5h.
Available structures PDB Ortholog search: PDBe, RCSB List of PDB id codes 1A5H, 1BDA, 1PK2, 1PML, 1RTF, 1TPG, 1TPK, 1TPM, 1TPN
Identifiers
Symbols	PLAT ; T-PA; TPA
External IDs	OMIM: 173370 MGI: 97610 HomoloGene: 717 ChEMBL: 1873 GeneCards: PLAT Gene
EC number	3.4.21.68
Gene ontology Molecular function • glycoprotein binding • serine-type endopeptidase activity • receptor binding • protein binding • phosphoprotein binding Cellular component • extracellular region • extracellular space • cytoplasm • cell surface • secretory granule • extracellular matrix • apical part of cell • extracellular exosome Biological process • response to hypoxia • cellular protein modification process • proteolysis • blood coagulation • smooth muscle cell migration • plasminogen activation • fibrinolysis • negative regulation of proteolysis • platelet-derived growth factor receptor signaling pathway Sources: Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	5327	18791
Ensembl	ENSG00000104368	ENSMUSG00000031538
UniProt	P00750	P11214
RefSeq (mRNA)	NM_000930	NM_008872
RefSeq (protein)	NP_000921	NP_032898
Location (UCSC)	Chr 8: 42.18 – 42.21 Mb	Chr 8: 22.76 – 22.78 Mb
PubMed search	[1]	[2]