Hey,
I tried the full uninstall, cleared any references in the registry and profile, then reinstalled. No joy unfortunately :( It still crashes a few seconds after loading into the initial game scene.
But I was able to install Windstone on two other windows 10 computers and it worked fine.
The only possible cause I could find was OpenSSL* SHA Crash Bug Requires Application Update (intel.com But changing this environment setting didn't fix the problem.
I know you must be busy and so I am happy to leave it at that. But if you find more players have the same problem, I would be happy to help you try and resolve the issue with further testing or running a debug build.
All the best :)