Papers by Mohamed Abd El Salam
We evaluated the role of Tribulus terrestris in males with unexplained
infertility and its effect... more We evaluated the role of Tribulus terrestris in males with unexplained
infertility and its effect on serum testosterone and semen parameters. Thirty randomized
male patients presenting to Andrology outpatient clinic complaining of idiopathic
infertility were selected. They were given Tribulus terrestris (750 mg) in three divided
doses for three months. The effect of Tribulus terrestris on serum testosterone (total
and free) and luteinizing hormone (LH), as well as its impact on semen parameters in
those patients, was studied. No statistically significant difference was observed in the
levels of testosterone (total and free) and LH and semen parameters (sperm concentration
or motility, or abnormal forms) before and after the treatment. In addition, no
statistically significant correlations were observed between testosterone (free and total)
and LH and semen parameters before and after the treatment. Tribulus terrestris was
ineffective in the treatment of idiopathic infertility.
We investigated the prevalence of 5HT2C receptor gene polymorphisms in Egyptian patients with lif... more We investigated the prevalence of 5HT2C receptor gene polymorphisms in Egyptian patients with lifelong premature ejaculation. A total of 350 participants were enrolled in a prospective study. Two hundred and forty-five cases with lifelong premature ejaculation joined this study, in addition to 105 controls. We instructed the partners of the cases to measure the IELT of the first intercourse only using a stopwatch for 1 month. Genotyping was carried out at the end of the study. The results showed that the majority of the patients and controls were Cys/Cys. A highly significant statistical association was found between the studied gene polymorphisms and IELT among cases (p-values = .009). The study emphasised the potential role of 5HT2C receptor gene polymorphisms in patients with lifelong premature ejaculation.
The most common cause for obstruction in the developing countries would be infection, while vasec... more The most common cause for obstruction in the developing countries would be infection, while vasectomy is the leading cause in developed countries . Iatrogenic injury-other than vasectomywas shown to be the cause of obstruction in 8-19% of patients diagnosed with obstructive azoospermia .
This study was conducted on 30 consecutive male patients presenting to Kasr-Al Ainy Andrology
out... more This study was conducted on 30 consecutive male patients presenting to Kasr-Al Ainy Andrology
outpatient clinic complaining of manifestations of partial androgen deficiency in aging males
(PADAM). In this study (750 mg/day) of Tribulus terrestris in 3 divided doses, each of 250 mg, as
an endogenous testosterone enhancer had been tried for a duration of 3 months and the evaluation of
its effect had been monitored for each patient concerning its effect on serum testosterone (total and
free) and luteinizing hormone (LH), as well as its impact on erectile function, which was evaluated
by the International Index of Erectile Function-5 (IIEF-5) questionnaire for those patients. Results
showed a statistically significant difference in the level of testosterone (total and free) and IIEF-5,
but no statistically significant difference in the level of LH before and after treatment. Also, the study
showed statistically significant correlation between testosterone (total and free) and IIEF-5, but no
statistically significant correlation between the level of LH and the IIEF-5 before and after treatment.
Delayed, failed, or arrested puberty is the consequence of hypogonadism among adolescent boys. A ... more Delayed, failed, or arrested puberty is the consequence of hypogonadism among adolescent boys. A variety of congenital and acquired conditions that affect the hypothalamus and/or the pituitary gland can lead to hypogonadotropic hypogonadism (HH). Congenital HH is mainly caused by genetic defects and is divided into two main categories based on the integrity of smell sensation: anosmic (Kallmann's syndrome) and normosmic isolated HH. Hormonal evaluation is the key diagnostic tool for the assessment of hypogonadism and basically includes testosterone, follicle-stimulating hormone, and luteinizing hormone. In borderline cases, several stimulation tests can be used, including luteinizing-hormone-releasing hormone, human chorionic gonadotropin, and clomiphene. Other hormones or imaging tests may be needed according to the cause and clinical presentation. Hormone replacement therapy is the main target in the treatment of HH and it includes either androgen therapy or gonadotropin-releasing hormone (GnRH)/gonadotropin therapy. Androgen replacement therapy is indicated to improve the symptoms and signs of hypogonadism. To achieve conception, GnRH or gonadotropin therapies are used. The proper time to start therapy is not well defined. At least 6–36 months of uninterrupted therapy is needed to achieve conception. Assisted reproductive techniques are indicated in case of failure to achieve conception with GnRH or gonadotropin therapy, depending on the quantity and quality of sperms and the fertility potential of the female. If azoospermia persists, testicular sperm extraction combined with intracytoplasmic sperm injection provides a successful option. Reversal of hypogonadism may occur in some patients receiving gonadotropins; thus short periods of interruption of treatment are advised.
Penile strangulation is considered a rare andrological emergency that may lead to a wide range of... more Penile strangulation is considered a rare andrological emergency that may lead to a wide range of complications. Penile strangulation may be related to mental retardation in children or hypersexuality, abnormal sexual preferences in adults. This case report shows a 23-year-old male who presented to the emergency room with agonizing pain related to a metallic ring placed at the base of the penis for more than 8 hours during an attempt of masturbation. Removing this metallic ring and saving the patient's penis from gangrene without causing injury were very challenging. Patient was successfully managed and had an uneventful recovery.
Priapism is considered as an unusual andrological emergency that requires urgent intervention. It... more Priapism is considered as an unusual andrological emergency that requires urgent intervention. It is defined as prolonged penile erection (usually painful) for more than 4 hours not related to sexual excitation or stimulation. Several causes have been attributed to cause such condition including the use of psychotropic drugs as chlorpromazine. Only few case reports in literature have recorded priapism as a complication of administration of chlorpromazine, however most of them were due to overdose or prolonged administration for prolonged period or as an interaction with other drugs. Here, in this case report is about a 23 years old male presented to the emergency department with neglected priapism after administration of a single dose of chlorpromazine.
Uploads
Papers by Mohamed Abd El Salam
infertility and its effect on serum testosterone and semen parameters. Thirty randomized
male patients presenting to Andrology outpatient clinic complaining of idiopathic
infertility were selected. They were given Tribulus terrestris (750 mg) in three divided
doses for three months. The effect of Tribulus terrestris on serum testosterone (total
and free) and luteinizing hormone (LH), as well as its impact on semen parameters in
those patients, was studied. No statistically significant difference was observed in the
levels of testosterone (total and free) and LH and semen parameters (sperm concentration
or motility, or abnormal forms) before and after the treatment. In addition, no
statistically significant correlations were observed between testosterone (free and total)
and LH and semen parameters before and after the treatment. Tribulus terrestris was
ineffective in the treatment of idiopathic infertility.
outpatient clinic complaining of manifestations of partial androgen deficiency in aging males
(PADAM). In this study (750 mg/day) of Tribulus terrestris in 3 divided doses, each of 250 mg, as
an endogenous testosterone enhancer had been tried for a duration of 3 months and the evaluation of
its effect had been monitored for each patient concerning its effect on serum testosterone (total and
free) and luteinizing hormone (LH), as well as its impact on erectile function, which was evaluated
by the International Index of Erectile Function-5 (IIEF-5) questionnaire for those patients. Results
showed a statistically significant difference in the level of testosterone (total and free) and IIEF-5,
but no statistically significant difference in the level of LH before and after treatment. Also, the study
showed statistically significant correlation between testosterone (total and free) and IIEF-5, but no
statistically significant correlation between the level of LH and the IIEF-5 before and after treatment.
infertility and its effect on serum testosterone and semen parameters. Thirty randomized
male patients presenting to Andrology outpatient clinic complaining of idiopathic
infertility were selected. They were given Tribulus terrestris (750 mg) in three divided
doses for three months. The effect of Tribulus terrestris on serum testosterone (total
and free) and luteinizing hormone (LH), as well as its impact on semen parameters in
those patients, was studied. No statistically significant difference was observed in the
levels of testosterone (total and free) and LH and semen parameters (sperm concentration
or motility, or abnormal forms) before and after the treatment. In addition, no
statistically significant correlations were observed between testosterone (free and total)
and LH and semen parameters before and after the treatment. Tribulus terrestris was
ineffective in the treatment of idiopathic infertility.
outpatient clinic complaining of manifestations of partial androgen deficiency in aging males
(PADAM). In this study (750 mg/day) of Tribulus terrestris in 3 divided doses, each of 250 mg, as
an endogenous testosterone enhancer had been tried for a duration of 3 months and the evaluation of
its effect had been monitored for each patient concerning its effect on serum testosterone (total and
free) and luteinizing hormone (LH), as well as its impact on erectile function, which was evaluated
by the International Index of Erectile Function-5 (IIEF-5) questionnaire for those patients. Results
showed a statistically significant difference in the level of testosterone (total and free) and IIEF-5,
but no statistically significant difference in the level of LH before and after treatment. Also, the study
showed statistically significant correlation between testosterone (total and free) and IIEF-5, but no
statistically significant correlation between the level of LH and the IIEF-5 before and after treatment.