മെലോക്സിക്കം

മെലോക്സിക്കം
Clinical data
Trade names	Mobic, Metacam, Anjeso, others
AHFS/Drugs.com	monograph
MedlinePlus	a601242
License data	US DailyMed: Meloxicam;
Pregnancy; category	AU: C ; ;
Routes of; administration	By mouth, intravenous
ATC code	M01AC06 (WHO) M01AC56, QM01AC06, QM01AC56;
Legal status
Legal status	AU: S4 (Prescription only); UK: POM (Prescription only); US: WARNINGRx-only; EU: Rx-only;
Pharmacokinetic data
Bioavailability	89%
Protein binding	99.4%
Metabolism	Liver (CYP2C9 and 3A4-mediated)
Elimination half-life	20 hours
Excretion	Urine and feces equally
Identifiers
	IUPAC name 4-Hydroxy-2-methyl-N-(5-methyl-2-thiazolyl)-2H-1,2-benzothiazine-3-carboxamide-1,1-dioxide;
CAS Number	71125-38-7 ;
PubChem CID	5281106;
IUPHAR/BPS	7220;
DrugBank	DB00814 ;
ChemSpider	10442740 ;
UNII	VG2QF83CGL;
KEGG	D00969 ;
ChEBI	CHEBI:6741 ;
ChEMBL	ChEMBL599 ;
PDB ligand	MXM (PDBe, RCSB PDB);
CompTox Dashboard (EPA)	DTXSID1020803 ;
ECHA InfoCard	100.113.257
Chemical and physical data
Formula	C14H13N3O4S2
Molar mass	351.40 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES Cc1cnc(s1)NC(=O)C\3=C(/O)c2ccccc2S(=O)(=O)N/3C;
	InChI InChI=1S/C14H13N3O4S2/c1-8-7-15-14(22-8)16-13(19)11-12(18)9-5-3-4-6-10(9)23(20,21)17(11)2/h3-7,18H,1-2H3,(H,15,16,19) ; Key:ZRVUJXDFFKFLMG-UHFFFAOYSA-N ;
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ഇംഗ്ലീഷ് വിലാസം

https://ml.wikipedia.org/wiki/Meloxicam

വാത രോഗങ്ങൾ, ഓസ്റ്റിയോ ആർത്രൈറ്റിസ് എന്നീ രോഗങ്ങൾ കൊണ്ടുണ്ടാകുന്ന വേദനയും വീക്കവും ചികിത്സിക്കാൻ ഉപയോഗിക്കുന്ന ഒരു നോൺ-സ്റ്റിറോയ്ഡൽ ആൻറി-ഇൻഫ്ലമേറ്ററി മരുന്നാണ് (NSAID) മോബിക് എന്ന ബ്രാൻഡ് നാമത്തിൽ വിൽക്കുന്ന മെലോക്സിക്കം. ^[6]^[7]ഇത് വായിലൂടെയോ സിരയിലേക്ക് കുത്തിവച്ചോ ഉപയോഗിക്കുന്നു.^[7]^[8] ഇത് കഴിയുന്നത്ര ചെറിയ കാലയളവിലും കുറഞ്ഞ അളവിലും ഉപയോഗിക്കാൻ ശുപാർശ ചെയ്യുന്നു.^[7]

References

↑ Use During Pregnancy and Breastfeeding
↑ "FDA-sourced list of all drugs with black box warnings (Use Download Full Results and View Query links.)". nctr-crs.fda.gov. FDA. Retrieved 22 Oct 2023.
↑ "Mobic- meloxicam tablet". DailyMed. Retrieved 15 May 2021.
↑ "Anjeso- meloxicam injection". DailyMed. Retrieved 15 May 2021.
↑ ^5.0 ^5.1 ^5.2 ^5.3 ^5.4 Noble S, Balfour JA (March 1996). "Meloxicam". Drugs. 51 (3): 424–30, discussion 431–32. doi:10.2165/00003495-199651030-00007. PMID 8882380.
↑ British national formulary : BNF 76 (76 ed.). Pharmaceutical Press. 2018. pp. 1112–1113. ISBN 9780857113382.
↑ ^7.0 ^7.1 ^7.2 "Meloxicam Monograph for Professionals". Drugs.com. AHFS. Archived from the original on 23 December 2018. Retrieved 23 December 2018.
↑ "Baudax Bio Announces FDA Approval of Anjeso for the Management of Moderate to Severe Pain". Baudax Bio, Inc. (Press release). 20 February 2020. Archived from the original on 21 February 2020. Retrieved 20 February 2020.

External links

"Meloxicam". Drug Information Portal. U.S. National Library of Medicine.

[Drugs.com_pregnancy-1] Use During Pregnancy and Breastfeeding

[FDA-AllBoxedWarnings-2] "FDA-sourced list of all drugs with black box warnings (Use Download Full Results and View Query links.)". nctr-crs.fda.gov. FDA. Retrieved 22 Oct 2023.

[Mobic_FDA_label-3] "Mobic- meloxicam tablet". DailyMed. Retrieved 15 May 2021.

[Anjeso_FDA_label-4] "Anjeso- meloxicam injection". DailyMed. Retrieved 15 May 2021.

[drugs1996-5] 5.0 ^5.1 ^5.2 ^5.3 ^5.4 Noble S, Balfour JA (March 1996). "Meloxicam". Drugs. 51 (3): 424–30, discussion 431–32. doi:10.2165/00003495-199651030-00007. PMID 8882380.

[BNF76-6] British national formulary : BNF 76 (76 ed.). Pharmaceutical Press. 2018. pp. 1112–1113. ISBN 9780857113382.

[AHFS2018-7] 7.0 ^7.1 ^7.2 "Meloxicam Monograph for Professionals". Drugs.com. AHFS. Archived from the original on 23 December 2018. Retrieved 23 December 2018.

[Anjeso_PR-8] "Baudax Bio Announces FDA Approval of Anjeso for the Management of Moderate to Severe Pain". Baudax Bio, Inc. (Press release). 20 February 2020. Archived from the original on 21 February 2020. Retrieved 20 February 2020.

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ക സ തി Non-steroidal anti-inflammatory drugs (NSAIDs) (primarily M01A and M02A, also N02BA)
pyrazolones / pyrazolidines	Aminophenazone Ampyrone Azapropazone Clofezone Difenamizole Famprofazone Feprazone Kebuzone Metamizole Mofebutazone Morazone Nifenazone Oxyphenbutazone Phenazone Phenylbutazone Propyphenazone Sulfinpyrazone Suxibuzone^‡
salicylates	Aspirin (acetylsalicylic acid)^# Aloxiprin Benorylate Carbasalate calcium Diflunisal Dipyrocetyl Ethenzamide Guacetisal Magnesium salicylate Methyl salicylate Salsalate Salicin Salicylamide Salicylic acid (salicylate) Sodium salicylate
acetic acid derivatives and related substances	Aceclofenac Acemetacin Alclofenac Amfenac Bendazac Bromfenac Bufexamac Bumadizone Diclofenac Difenpiramide Etodolac Felbinac Fenclozic acid Fentiazac Indometacin Indometacin farnesil Isoxepac Ketorolac Lonazolac Mofezolac Oxametacin Prodolic acid Proglumetacin Sulindac Tiopinac Tolmetin Zomepirac^†
oxicams	Ampiroxicam Droxicam Isoxicam Lornoxicam Meloxicam Piroxicam Pivoxicam Tenoxicam
propionic acid derivatives (profens)	Alminoprofen Benoxaprofen^† Carprofen^‡ Dexibuprofen Dexketoprofen Fenbufen Fenoprofen Flunoxaprofen Flurbiprofen Ibuprofen^# Ibuproxam Indoprofen^† Ketoprofen Loxoprofen Miroprofen Naproxen Oxaprozin Piketoprofen Pirprofen Suprofen Tarenflurbil Tepoxalin^‡ Tiaprofenic acid Vedaprofen^‡ Zaltoprofen COX-inhibiting nitric oxide donator: Naproxcinod
n-arylanthranilic acids (fenamates)	Azapropazone Clonixin Etofenamate Floctafenine Flufenamic acid Flunixin Flutiazin Glafenine^† Meclofenamic acid Mefenamic acid Morniflumate Niflumic acid Tolfenamic acid
COX-2 inhibitors (coxibs)	Apricoxib Celecoxib (+tramadol) Cimicoxib^‡ Deracoxib^‡ Etoricoxib Firocoxib^‡ Lumiracoxib^† Mavacoxib^‡ Parecoxib Robenacoxib^‡ Rofecoxib^† Valdecoxib^†
other	Aminopropionitrile Benzydamine Chondroitin sulfate Diacerein Fluproquazone Glucosamine Glycosaminoglycan Hyperforin Nabumetone Nimesulide Oxaceprol Proquazone Superoxide dismutase / orgotein Tenidap
NSAID combinations	Ibuprofen/famotidine Ibuprofen/hydrocodone Ibuprofen/oxycodone Ibuprofen/paracetamol Meloxicam/bupivacaine Naproxen/diphenhydramine Naproxen/esomeprazole
Key: underline indicates initially developed first-in-class compound of specific group; ^#WHO-Essential Medicines; ^†withdrawn drugs; ^‡veterinary use.
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