Crest disease

Scleroderma is a rare and chronic autoimmune disease characterized by hardening and tightening of the body’s connective tissue.

CREST syndrome is type of scleroderma is believed to be an autoimmune disorder. Mostly in lower arms and legs, below the elbows and knees, and sometimes affect the face and neck. Limited scleroderma…

Rheumatic Diseases and Antibodies – Neuros | Medical Social Network

Learn more about scleroderma and systemic sclerosis, an autoimmune disease that affects the skin and internal organs.

CREST Syndrome (Limited Scleroderma) Systemic scleroderma, or systemic sclerosis, is the term for the disease that is characterized by diffuse thickening of the skin, but may also involves the tissues beneath to the blood vessels and major organs. Systemic sclerosis is typically categorized into diffuse and limited disease. Limited scleroderma disease develops gradually and generally

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You may be wondering, what is scleroderma? Below, we explore what causes scleroderma, what the symptoms of scleroderma are, and what treatments for scleroderma are available. Remember, you are not alone, and there are many sources of support available to you and your family.

#Scl70 #antibodies (topoisomerase 1) are a 100-kD #nuclear and #nucleolarenzyme which are considered to be specific for #Scleroderma and are found in nearly 60% of patients having this connective tissue disease.

Raynaud Syndrome - Etiology, pathophysiology, symptoms, signs, diagnosis & prognosis from the Merck Manuals - Medical Professional Version.