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| metabolism =
| metabolism =
| elimination_half-life =
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<!--Identifiers-->
<!--Identifiers-->
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<!--Chemical data-->
<!--Chemical data-->
| C=11 | H=17 | N=5 | O=2
| C=11 | H=17 | N=5 | O=2
| molecular_weight = 251,29 -{g/mol}-
| molecular_weight = 251,29 g/mol
| smiles = O=C2N(c1ncn(c1C(=O)N2C)CCN(C)C)C
| smiles = O=C2N(c1ncn(c1C(=O)N2C)CCN(C)C)C
| InChI =
| InChI =
| InChIKey =
| InChIKey =
| StdInChI_Ref = {{stdinchicite|correct|chemspider}}
| StdInChI_Ref = {{stdinchicite|correct|chemspider}}
| StdInChI = 1S/C11H17N5O2/c1-13(2)5-6-16-7-12-9-8(16)10(17)15(4)11(18)14(9)3/h7H,5-6H2,1-4H3
| StdInChI =
| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}
| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}
| StdInChIKey =
| StdInChIKey = CMKUGKVVUUGBHJ-UHFFFAOYSA-N
}}
}}


'''Dimetazan''' (''Elidin'') je [[Психостимуланс|stimulansni]] [[lek]] iz [[ksantin]]ske klase. On je srodan sa [[kofein]]om i [[teofilin]]om.<ref name="pmid13559232">{{cite journal | author=Batterman RC, Grossman AJ, Leifer P, Mouratoff GJ | title = Central nervous system stimulation and sedation with dimethazan | journal = The American Journal of the Medical Sciences | volume = 236 | issue = 2 | pages=162–7 | year = 1958 | month = August | pmid = 13559232 | doi = | url = }}</ref> On takođe ima [[Anksiolitik|umirujuće]] i [[Респирација|respiratorno]] stimulišuće dejstvo i bio je u prodaji kao [[antidepresiv]].<ref name=autogenerated1>{{cite journal | author = BATTERMAN RC, GROSSMAN AJ, LEIFER P, MOURATOFF GJ | title = Central nervous system stimulation and sedation with dimethazan | journal = The American Journal of the Medical Sciences | volume = 236 | issue = 2 | pages=162–7 | year = 1958 | month = August | pmid = 13559232 | doi = | url = }}</ref><ref name="isbn0-911910-13-1">{{Cite book | author = O'Neil, Maryadele J. | title = The Merck index: an encyclopedia of chemicals, drugs, and biologicals | publisher = Merck Research Laboratories | location = Rahway, NJ | year = 2001 | pages = | isbn = 0-911910-13-1 | oclc = | doi = | accessdate = }}</ref>
'''Dimetazan''' (''Elidin'') je [[Psihostimulans|stimulansni]] [[lek]] iz [[ksantin]]ske klase. On je srodan sa [[kofein]]om i [[teofilin]]om.<ref name="pmid13559232">{{cite journal | author=Batterman RC, Grossman AJ, Leifer P, Mouratoff GJ | title = Central nervous system stimulation and sedation with dimethazan | journal = The American Journal of the Medical Sciences | volume = 236 | issue = 2 | pages=162–7 | year = 1958 | month = August | pmid = 13559232 | doi = | url =https://archive.org/details/sim_american-journal-of-the-medical-sciences_1958-08_236_2/page/162}}</ref> On takođe ima [[Anksiolitik|umirujuće]] i [[Respiracija|respiratorno]] stimulišuće dejstvo i bio je u prodaji kao [[antidepresiv]].<ref name=autogenerated1>{{cite journal | author = BATTERMAN RC, GROSSMAN AJ, LEIFER P, MOURATOFF GJ | title = Central nervous system stimulation and sedation with dimethazan | journal = The American Journal of the Medical Sciences | volume = 236 | issue = 2 | pages=162–7 | year = 1958 | month = August | pmid = 13559232 | doi = | url =https://archive.org/details/sim_american-journal-of-the-medical-sciences_1958-08_236_2/page/162}}</ref><ref name="isbn0-911910-13-1">{{Cite book | author = O'Neil, Maryadele J. | title = The Merck index: an encyclopedia of chemicals, drugs, and biologicals | url = https://archive.org/details/merckindexency00onei | publisher = Merck Research Laboratories | location = Rahway, NJ | year = 2001 | pages = | isbn = 0-911910-13-1 | oclc = | doi = | accessdate = }}</ref>


== Reference ==
== Reference ==
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== Literatura ==
== Literatura ==
* {{Cite book |ref= harv|author=O'Neil, Maryadele J. | title = The Merck index: an encyclopedia of chemicals, drugs, and biologicals | publisher = Merck Research Laboratories | location = Rahway, NJ | year = 2001 | pages = | isbn = 0-911910-13-1 | oclc = | doi = | accessdate = }}
* {{Cite book |ref= harv|author=O'Neil, Maryadele J. | title = The Merck index: an encyclopedia of chemicals, drugs, and biologicals |url= https://archive.org/details/merckindexency00onei| publisher = Merck Research Laboratories | location = Rahway, NJ | year = 2001 | pages = | isbn = 0-911910-13-1 | oclc = | doi = | accessdate = }}


== Vidi još ==
== Povezano ==
* [[Ksantin]]
* [[Ksantin]]


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[[Kategorija:Antidepresanti]]
[[Kategorija:Antidepresanti]]
[[Kategorija:Adenozinski antagonisti]]
[[Kategorija:Adenozinski antagonisti]]
[[Kategorija:Ksantini]]
[[Категорија:Ксантини]]

Aktualna verzija od 18. augusta 2024. u 00:07

Dimetazan
(IUPAC) ime
7-(2-dimetilaminoetil)-1,3-dimetil-purin-2,6-dion
Klinički podaci
Identifikatori
CAS broj 519-30-2
ATC kod nije dodeljen
PubChem[1][2] 10612
ChemSpider[3] 10167
UNII H943V308AD DaY
Hemijski podaci
Formula C11H17N5O2 
Mol. masa 251,29 g/mol
SMILES eMolekuli & PubHem
Sinonimi 1,3-dimetil-7-(2-dimetilaminoetil)ksantin;
7-(2-dimetilaminoetil)teofilin
Farmakoinformacioni podaci
Trudnoća ?
Pravni status ℞ Prescription only
Način primene Oralno

Dimetazan (Elidin) je stimulansni lek iz ksantinske klase. On je srodan sa kofeinom i teofilinom.[4] On takođe ima umirujuće i respiratorno stimulišuće dejstvo i bio je u prodaji kao antidepresiv.[5][6]

Reference

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  1. ↑ Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519.  edit
  2. ↑ Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1. 
  3. ↑ Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). „Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining”. J Cheminform 2 (1): 3. DOI:10.1186/1758-2946-2-3. PMID 20331846.  edit
  4. ↑ Batterman RC, Grossman AJ, Leifer P, Mouratoff GJ (August 1958). „Central nervous system stimulation and sedation with dimethazan”. The American Journal of the Medical Sciences 236 (2): 162–7. PMID 13559232. 
  5. ↑ BATTERMAN RC, GROSSMAN AJ, LEIFER P, MOURATOFF GJ (August 1958). „Central nervous system stimulation and sedation with dimethazan”. The American Journal of the Medical Sciences 236 (2): 162–7. PMID 13559232. 
  6. ↑ O'Neil, Maryadele J. (2001). The Merck index: an encyclopedia of chemicals, drugs, and biologicals. Rahway, NJ: Merck Research Laboratories. ISBN 0-911910-13-1. 

Literatura

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Povezano

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Spoljašnje veze

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Portal Medicina
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Izvor: https://sh.wikipedia.org/w/index.php?title=Dimetazan&oldid=42170150