Ehinopsidin

Ehinopsidin
(IUPAC) ime
	1-Metil-2,3-dihidrohinolin-4-imin
Klinički podaci
Identifikatori
CAS broj	2400-75-1 ; 58916-73-7 (hidrojodid)
ATC kod	nije dodeljen
PubChem	161462
ChemSpider	141825
Hemijski podaci
Formula	C10H12N2
Mol. masa	160,22 g/mol
SMILES	eMolekuli & PubHem
InChI
	InChI=1S/C10H12N2/c1-12-7-6-9(11)8-4-2-3-5-10(8)12/h2-5,11H,6-7H2,1H3 ; Key: GKGBJWPUGWCYNT-UHFFFAOYSA-N
Sinonimi	Ehinopsidin Jodid
Farmakoinformacioni podaci
Trudnoća	?
Pravni status	℞ Prescription only
Način primene	Oralno

Ehinopsidin (Adepren) je antidepresiv koji je korišćen u Bugarskoj za tretiranje depresije.^[4]^[5] On povišava nivoe serotonina, norepinefrina, i dopamina u mozgu i smatra se da deluje kao inhibitor monoaminske oksidaze (MAOI).^[6]^[7]^[8] Ehinopsidin se prirodno javlja u Echinops echinatus zajedno sa srodnim alkaloidima ehinopsinom i ehinozolinonom.^[9]

Reference

↑ Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519. edit
↑ Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1.
↑ Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). „Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining”. J Cheminform 2 (1): 3. DOI:10.1186/1758-2946-2-3. PMID 20331846. edit
↑ Guliamov MG (1982). „[Experience with the use of new Bulgarian psychotropic drugs]” (Russian). Zhurnal Nevropatologii I Psikhiatrii Imeni S.S. Korsakova (Moscow, Russia : 1952) 82 (11): 115–22. PMID 6758442.
↑ Guliamov MG (1986). „[Comparative evaluation of the therapeutic efficacy of the antidepressants adepren, linamiphen and emovit]” (Russian). Zhurnal Nevropatologii I Psikhiatrii Imeni S.S. Korsakova (Moscow, Russia : 1952) 86 (4): 582–7. PMID 3716711.
↑ Tiutiulkova N, Gorancheva Iu (1978). „[Effect of adepren on the cerebral concentration of serotonin]” (Bulgarian). Eksperimentalna Meditsina I Morfologiia 17 (2): 83–5. PMID 658004.
↑ Stefanova D, Tiutiulkova N, Nikolova M (1976). „[Effect of adepren on the behavior and brain catecholamines of rats in an open field setup]” (Bulgarian). Eksperimentalna Meditsina I Morfologiia 15 (1): 42–6. PMID 1269462.
↑ Tiutiulkova NI, Gorancheva IuI (1975). „[Excretion of dopamine, noradrenaline, adrenaline, vanilmandelic acid and 5-hydroxyindoleacetic acid in the urine of volunteers treated with adepren]” (Bulgarian). Eksperimentalna Meditsina I Morfologiia 14 (4): 187–9. PMID 1222713.
↑ Indian Medicinal Plants An Illustrated Dictionary. Springer-Verlag Berlin Heidelberg. 2007. ISBN 0-387-70637-2.

Литература

Indian Medicinal Plants An Illustrated Dictionary. Springer-Verlag Berlin Heidelberg. 2007. ISBN 0-387-70637-2.

Povezano

Inhibitor monoaminske oksidaze

Spoljašnje veze

	Portal Medicina
	Portal Hemija

[1] Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519. edit

[2] Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1.

[3] Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). „Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining”. J Cheminform 2 (1): 3. DOI:10.1186/1758-2946-2-3. PMID 20331846. edit

[pmid6758442-4] Guliamov MG (1982). „[Experience with the use of new Bulgarian psychotropic drugs]” (Russian). Zhurnal Nevropatologii I Psikhiatrii Imeni S.S. Korsakova (Moscow, Russia : 1952) 82 (11): 115–22. PMID 6758442.

[pmid3716711-5] Guliamov MG (1986). „[Comparative evaluation of the therapeutic efficacy of the antidepressants adepren, linamiphen and emovit]” (Russian). Zhurnal Nevropatologii I Psikhiatrii Imeni S.S. Korsakova (Moscow, Russia : 1952) 86 (4): 582–7. PMID 3716711.

[pmid658004-6] Tiutiulkova N, Gorancheva Iu (1978). „[Effect of adepren on the cerebral concentration of serotonin]” (Bulgarian). Eksperimentalna Meditsina I Morfologiia 17 (2): 83–5. PMID 658004.

[pmid1269462-7] Stefanova D, Tiutiulkova N, Nikolova M (1976). „[Effect of adepren on the behavior and brain catecholamines of rats in an open field setup]” (Bulgarian). Eksperimentalna Meditsina I Morfologiia 15 (1): 42–6. PMID 1269462.

[pmid1222713-8] Tiutiulkova NI, Gorancheva IuI (1975). „[Excretion of dopamine, noradrenaline, adrenaline, vanilmandelic acid and 5-hydroxyindoleacetic acid in the urine of volunteers treated with adepren]” (Bulgarian). Eksperimentalna Meditsina I Morfologiia 14 (4): 187–9. PMID 1222713.

[isbn0-387-70637-2-9] Indian Medicinal Plants An Illustrated Dictionary. Springer-Verlag Berlin Heidelberg. 2007. ISBN 0-387-70637-2.

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