Particulate matter (PM) is considered as one of the major pollutants that affect the health of humans, especially for the fine and ultrafine fraction, which can adsorb greater concentrations of toxic compounds, e.g., polycyclic aromatic...
moreParticulate matter (PM) is considered as one of the major pollutants that affect the health of humans, especially for the fine and ultrafine fraction, which can adsorb greater concentrations of toxic compounds, e.g., polycyclic aromatic hydrocarbons (PAHs). PAHs are a group of several complex organic compounds consisting of carbon and hydrogen, and two or more condensed benzene rings and represent one of the most stable families of organic compounds known. The known carcinogens isomers are primarily associated with particulate material and, usually, the highest concentrations are in the respirable fraction <5 µm. High PAHs levels in ambient air of large metropolitan areas are usually associated with vehicular emissions, including diesel and gasoline vehicles. Particle-bound PAHs in the fine and ultrafine fraction present a higher risk because they can deposit in the respiratory tract, hence aggravating the potentially negative health effects. In addition, some PAHs are possibly or probably carcinogenic to humans (benzo[a]anthracene, benzo[b]fluoranthene, benzo[k] fluoranthene, benzo[a]pyrene, dibenzo[a,h] anthracene, and indeno[1,2,3-cd]pyrene). Thus, there is considerable concern about the relationship between PAHs exposure in the ambient air and the potential to contribute to human cancer incidence. The objective of this study was to conduct an assessment of carcinogenic and mutagenic risks of the studied PAHs in the PM1.0, PM2.5 and PM2.5-10 samples. The toxic equivalent factors were calculated to characterize more accurately the risk of cancer from PAH exposure in the PM samples. This was based on the contribution of the carcinogenic potency of benzo[a]pyrene. The ambient concentrations of 12 PAHs, beginning from fluorene, and their toxic equivalence factor (TEF) were used in the calculation. The carcinogenic risk for five carcinogenic PAHs (Chr, BaA, BaP, Ind, and DahA) in the PM2.5 and PM2.5–10 fractions ranged from 44.9% to 56.8%, of DahA ranged from 35.12% to 44.63%, and of Ind ranged from 5.24% to 6.65% of the total carcinogenic activity in the study area. For PM1.0 fraction, BaP and DahA dominated the BaPeq levels. The carcinogenicity activity contribution of BaP was in the range of 27.1% (Canoas summer) up to 44.0% (Sapucaia winter); and the contribution of DahA was of 22.7% (Sapucaia winter) up to 45.3% (Canoas summer). The contribution of Ind for the BaPeq levels was of 15.0% (Sapucaia summer) up to 17.8% (Sapucaia winter). Since 2006 to 2013, the highest BaPeq levels were observed in winter in the study, and there has not been an increase in the contribution in the BaPeq levels of potentially carcinogenic PAHs, except for Ind. The recent established air quality limit of the European Parliament, the scientific publication of the IARC and the carcinogenic risk demonstrate the importance that these pollutants require maximum reduction and their study. These results may help the environmental agency and government to have tools to control PAHs in ambient air.