Microarray Data Analysis
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Recent papers in Microarray Data Analysis
A large variation in prognosis is observed despite the use of clinical prognostic factors in patients with advanced non-small cell lung cancer (NSCLC). It is likely that this variation is due to the different biological properties of the... more
Over the past few years, there has been a considerable spread of microarray technology in many biological patterns, particularly in those pertaining to cancer diseases like leukemia, prostate, colon cancer, etc. The primary bottleneck... more
This paper focuses on feature selection for problems dealing with high-dimensional data. We discuss the benefits of adopting a regularized approach with L 1 or L 1–L 2 penalties in two different applications—microarray data analysis in... more
The breakdown of the epidermal barrier and consequent loss of skin hydration is a feature of skin aging and eczematous dermatitis. Few treatments, however, resolve these underlying processes to provide full symptomatic relief. In this... more
Rainfall is very important aspect for farmers in day-to-day agriculture and also very important in prospect to Indian economical growth. As now a day we see there is daily climate change in our India as there no stable season any month... more
Sequencing projects arising from high-throughput technologies including those of sequencing DNA microarray allowed measuring simultaneously the expression levels of millions of genes of a biological sample as well as to annotate and to... more
The classification of different types of tumor is of great importance in cancer diagnosis and drug discovery. Earlier studies on cancer classification have limited diagnostic ability. The recent development of DNA microarray technology... more
Background: Terminalia chebula (TC) is a deciduous tree of which extracts have demonstrated efficacy for treatment of photodamage, skin aging, and wound healing. However, molecular and cellular mechanisms underlying these benefits remain... more
The key to the keys to immortality and eternal youth lies in the correct answer to the main question: How to naively discover new essential – but still hidden – features required for properly training novel adaptive supervised machine... more
Hepatocellular carcinoma (HCC) is a major malignancy in the liver and has emerged as one of the main cancers in the world with a high mortality rate. However, the molecular mechanisms of HCC are still poorly understood. Long noncoding... more
Microarray technology has become an emerging trend in the domain of genetic research in which many researchers employ to study and investigate the levels of genes' expression in a given organism. Microarray experiments have lots of... more
Galanin (GAL) and GAL receptors (GALR) are overexpressed in limbic brain regions associated with cognition in Alzheimer disease (AD). The functional consequences of GAL plasticity in AD are unclear. Because GAL inhibits cholinergic... more
Zingerone (Z) is a phenolic alkanone derived from natural sources with anti-inflammatory and antioxidant effects. Acetyl zingerone (AZ) is a recently designed molecule that shares structural features with Z but is expected to have... more
The term big-data in the context of materials science not only stands for the volume, but also for the heterogeneous nature of the characterization data-sets. This is a common problem in combinatorial searches in materials science, as... more
We studied genome-wide gene expression from bald and haired scalp of individuals to evaluate pathogenic mechanisms underlying the development and progression of androgenetic alopecia (AGA). Unbiased analyses revealed a “bald pathology”... more
Determining risky software projects early is a very important factor for project success. In this study it is aimed to choose the most correctly resulting modelling method that will be useful for early prediction of risky software... more
Gene expression microarrays are a prominent experimental tool in functional genomics which has opened the opportunity for gaining global, systems-level understanding of transcriptional networks. Experiments that apply this technology... more
Genes contain blue print of living organism. Malfunctioning occurred in cellular life is indicated by proteins which are responsible for behavior of genes. Fixed set of genes decides behavior and functioning of cells. They guide the cells... more
Aging is one of the chief biomedical problems of the 21st century. After decades of basic research on biogerontology (the science of aging), the aging process still remains an enigma. Although hundreds of "theories" on aging have been... more
A multiplex DNA microarray chip was developed for simultaneous identification of nine genetically modified organisms (GMOs), five plant species and three GMO screening elements, i.e. the 35S promoter, the nos terminator and the nptII... more