Origin and history of sicko

Middle English sik, from Old English seoc "ill, unwell, diseased, feeble, weak; corrupt; sad, troubled, deeply affected by strong feeling," from Proto-Germanic *seuka-, which is of uncertain origin.

It is the general Germanic word (compare Old Norse sjukr, Danish syg, Old Saxon siok, Old Frisian siak, Middle Dutch siec, Dutch ziek, Old High German sioh, Gothic siuks "sick, ill"), but in German and Dutch it was displaced by krank "weak, slim," probably via the notion of "twisted, bent" (see crank (n.)).

The restricted meaning of English sick, "having an inclination to vomit, affected with nausea," is from 1610s. By c. 1200 as "distressed emotionally by grief, anger, etc.; physically ill through emotional distress. The sense of "tired or weary (of something), disgusted from satiety" is from 1590s; the figurative phrase sick and tired of is attested from 1783. To worry (oneself) sick is by 1952.

The modern colloquial meaning "mentally twisted" is by 1955, a revival of the word's use in this sense from 1550s (the sense of "spiritually or morally corrupt" was in Old English, which also had seocmod "infirm of mind"). Sick joke is attested by 1958.

"strange person," by 1950, from weird + -o. As an adjective by 1962. Compare earlier Scottish weirdie "odd, unconventional person" (by 1887).

[Marlon] Brando said Tallulah Bankhead—with whom he performed in "An Eagle Has Two Heads"—considered him a "weird-o." [Press of Atlantic City (N.J.), May 18, 1950]

Also a surname in New Jersey.

as in beatnik, etc., suffix used in word formation from c. 1945, from Yiddish -nik (as in nudnik "a bore"), from Russian -nik, common personal suffix meaning "person or thing associated with or involved in" (compare nudnik; kolkhoznik "member of a kolkhoz"). Rocketed to popularity with sputnik (q.v.), hence its brief vogue in English word-formation, as in robotnik "person behaving with mindless obedience" (1960).