Then we used the GLUT-4 antagonist
indinavir to exam the function of GLUT-4 and we observed that the uptake of 2-NBDG decreased when the
indinavir was applied.
Ingrown toenail and
indinavir: A case control study demonstrates strong relationship.
[12] Prominent effects are observed with
Indinavir and ritonavir, diabetes began to appear when the drugs are in use in HIV-infected patients.
Indinavir and ritonavir are anti-HIV agents that selectively inhibit the HIV type 1 protease (9).
Increased incidence of
indinavir nephrolithiasis in patients with hepatitis B or C virus infection.
De estos compuestos el que tiene mayor afinidad por la proteina es el compuesto 18939759 que se encontraba en el grupo del
Indinavir. En la figura 1 se muestra los sitios de interaccion del ligando con la proteina correspondientes a los residuos; Asn 301, Asp 86, Thr 222, Thr 221 (con dos interacciones), Tir 225 y Asn 131.
All pregnant ladies, first time stone formers and those patients taking antacid,
indinavir or potassium sparing diuretics were excluded from the study.
In another report, three protease inhibitors
indinavir (IDV), LPV, and RTV were determined simultaneously by UPLC-MS/MS [26].
"Old HAART" was defined as triple combination antiretroviral regimens containing
indinavir, saquinavir, fosamprenavir, nelfinavir, or nevirapine.
For example, one study found that supplementation with 1000 mg per day of vitamin C decreased plasma
indinavir concentrations in patients receiving
indinavir as a component of HAART.
Indinavir, a protease inhibitor used in the treatment of HIV infection, is a well-documented cause of crystal-induced acute kidney injury and chronic kidney disease.
Because depression is common among patients with HIV, my colleagues and I evaluated the pharmacokinetic effects of
indinavir on venlafaxine and venlafaxine on
indinavir to determine if venlafaxine would be safe to use in a patient taking a PI because of potential cytochrome P450 (CYP450) drug interactions in both classes of medications.2 Adding ven-lafaxine resulted in a 36% decrease in maximum concentrations for
indinavir and a 28% decrease in area under the curve (Figure).2 Study participants were healthy individuals; however, we concluded that had we studied patients with HIV,
indinavir efficacy could decrease, resulting in an increased viral load.
