High-dose tamoxifen and
sulindac as first-line treatment for desmoid tumours.
Randomized phase II trial of
sulindac, atorvastatin and prebiotic dietary fiber for colorectal cancer chemoprevention.
In addition,
sulindac, ibuprofen, piroxicam, and aspirin have been shown to decrease the recurrence, incidence, mortality rate, and number of cancer cells in a significant manner.
Sorts of interactions between lithium and different NSAIDs Well-established interaction Celecoxib, diclofenac, flurbiprofen, ([a] lithium) indomethacin, ketorolac, ketoprofen, lornoxicam, mefenamic acid, meloxicam, niflumic acid, phenylbutazone, piroxicam Variable interaction Ibuprofen and naproxen ([b] or [a] or [c] lithium) Without proven interaction Acetylsalicylic acid and
sulindac [a] no change; [b] slight increase; [c][up arrow] moderate increase.
Sulindac compounds facilitate the cytotoxicity of [beta]-lapachone by up-regulation of NAD(P)H quinone oxidoreductase in human lung cancer cells.
Tamoxifen is often used in combination with NSAIDs (indomethacin or
sulindac) [11,12].
Moeslein, "High-dose tamoxifen and
sulindac as first-line treatment for desmoid tumors," Cancer, vol.
Administration of the carcinogen azoxymethane (AOM) causes multiple tumors in the distal colon and this is prevented or reduced by
sulindac, a nonsteroidal anti-inflammatory drug (NSAID) [10, 11].
For the study, the researchers separated 52 mice with colon cancer tumors into three groups, including a control group and groups that were fed either the grape compounds or
sulindac, an anti-inflammatory drug.
Photoprotective effects of
sulindac against ultraviolet B-induced phototoxicity in the skin of SKH-1 hairless mice.
For the animal study, they separated 52 mice with colon cancer tumors into three groups, including a control group and groups that were fed either the grape compounds or
sulindac, an anti-inflammatory drug, which was chosen because a previous study showed it significantly reduced the number of tumors in humans.
Role of
Sulindac and Celecoxib in the regulation of angiogenesis during the early neoplasm of colon: exploring PI3-K/PTEN/ Akt pathway to the canonical Wnt/b-catenin signaling.
(g) lbuprofen, aceclofenac, acemetacin, dexibuprofen, dexketoprofen, diclofenac sodium, diflunisal, etodolac, fenbufen, fenoprofen, flurbiprofen, ibuprofen, indometacin, ketoprofen, mefenamic acid, meloxicam, nabumetone, naproxen, piroxicam,
sulindac, tenoxicam, tiaprofenic acid, diclofenac/misoprostol.
Saidi et al., "Exisulind (
sulindac sulfone) suppresses growth of human prostate cancer in a nude mouse xenograft model by increasing apoptosis," Urology, vol.