Aclarubicin
From Infogalactic: the planetary knowledge core
Systematic (IUPAC) name | |
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(1S,2S,4R)-Methyl 4-(((2S,5R,6R)-4-(dimethylamino)-5-(((1S,3R,4S)-3-hydroxy-5-methyl-4-(((2S,6R)-6-methyl-5-oxotetrahydro-2H-pyran-2-yl)oxy)cyclohexyl)oxy)-6-methyltetrahydro-2H-pyran-2-yl)oxy)-2-ethyl-2,5,7-trihydroxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracene-1-carboxylate
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Clinical data | |
AHFS/Drugs.com | International Drug Names |
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Routes of administration |
IV |
Identifiers | |
CAS Number | 57576-44-0 |
ATC code | L01DB04 (WHO) |
PubChem | CID: 42474 |
ChemSpider | 1931 |
UNII | 74KXF8I502 |
KEGG | D02756 |
ChEBI | CHEBI:74619 |
ChEMBL | CHEMBL502620 |
Chemical data | |
Formula | C42H53NO15 |
Molecular mass | 811.86 g/mol |
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Aclarubicin (INN) or aclacinomycin A[1] is an anthracycline drug[2] that is used in the treatment of cancer. Soil bacteria Streptomyces galilaeus can produce aclarubicin. It can induce histone eviction from chromatin upon intercalation.[3][4]
References
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