Cycrimine

Systematic (IUPAC) name
	1-Cyclopentyl-1-phenyl-3-(piperidin-1-yl)propan-1-ol
Licence data	US FDA:link
Identifiers
CAS Number	77-39-4
ATC code	none
PubChem	CID: 2911
DrugBank	DB00942
ChemSpider	2808
UNII	543567RFQQ
ChEBI	CHEBI:59692
ChEMBL	CHEMBL1201227
Chemical data
Formula	C19H29NO
Molecular mass	287.4 g/mol
	SMILES OC(CCN1CCCCC1)(C2CCCC2)c3ccccc3 ;
	InChI InChI=1S/C19H29NO/c21-19(18-11-5-6-12-18,17-9-3-1-4-10-17)13-16-20-14-7-2-8-15-20/h1,3-4,9-10,18,21H,2,5-8,11-16H2 ; Key:SWRUZBWLEWHWRI-UHFFFAOYSA-N ;

Cycrimine (trade name Pagitane) is a central anticholinergic drug designed to reduce the levels of acetylcholine in the treatment of Parkinson's disease. Its mechanism of action is to bind to the muscarinic acetylcholine receptor M1.^[1]

Synthesis

Cycrimine synthesis:^[2]

↑ Psychotropic Drugs and Related Compounds, 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972, page 218
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