FGIN-143

FGIN-143

Systematic (IUPAC) name
2-[2-(4-chlorophenyl)-5-chloro-1H-indol-3-yl]-N,N-dihexylacetamide
Identifiers
CAS Number	145040-29-5
PubChem	CID: 3995234
Chemical data
Formula	C28H36Cl2N2O
Molecular mass	487.503 g/mol
SMILES c3cc(Cl)ccc3-c2nc1ccc(Cl)cc1c2CC(=O)N(CCCCCC)CCCCCC
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FGIN-1-43 is an anxiolytic drug which acts as a selective agonist at the peripheral benzodiazepine receptor, also known as the mitochondrial 18 kDa translocator protein or TSPO. It is thought to produce anxiolytic effects by stimulating steroidogenesis of neuroactive steroids such as allopregnanolone, and is several times more potent than the related drug FGIN-127.