Gossypetin

Gossypetin

Names
IUPAC name 2-(3,4-dihydroxyphenyl)-3,5,7,8-tetrahydroxychromen-4-one
Other names Articulatidin Equisporol 3,3',4',5,7,8-Hexahydroxyflavone 3,5,7,8,3',4'-Hexahydroxyflavone
Identifiers
CAS Number	489-35-0 Y
ChEBI	CHEBI:16400 N
ChEMBL	ChEMBL253570 N
ChemSpider	4444247 N
Jmol 3D model	Interactive image
PubChem	5280647
InChI InChI=1S/C15H10O8/c16-6-2-1-5(3-7(6)17)14-13(22)12(21)10-8(18)4-9(19)11(20)15(10)23-14/h1-4,16-20,22H N Key: YRRAGUMVDQQZIY-UHFFFAOYSA-N N InChI=1/C15H10O8/c16-6-2-1-5(3-7(6)17)14-13(22)12(21)10-8(18)4-9(19)11(20)15(10)23-14/h1-4,16-20,22H Key: YRRAGUMVDQQZIY-UHFFFAOYAI
SMILES C1=CC(=C(C=C1C2=C(C(=O)C3=C(O2)C(=C(C=C3O)O)O)O)O)O
Properties
Chemical formula	C15H10O8
Molar mass	318.23 g/mol
Vapor pressure	{{{value}}}
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is YN ?)
Infobox references

Gossypetin is a flavonol, a type of flavonoid. It has been isolated from the flowers and the calyx of Hibiscus sabdariffa (roselle) and exhibits a strong antibacterial activity.

Gosspetin has been found to act as an antagonist of TrkB.

Metabolism

The enzyme 8-hydroxyquercetin 8-O-methyltransferase uses S-adenosyl methionine and gossypetin to produce S-adenosylhomocysteine and 3,5,7,3',4'-pentahydroxy-8-methoxyflavone. Recently it was shown that gossypetin has radioprotective activity.

See also

• 7,8-Dihydroxyflavone
• Norwogonin
• Diosmetin