Iltovirus

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Iltovirus
Virus classification
Group:
Group I (dsDNA)
Order:
Family:
Subfamily:
Genus:
Iltovirus
Type Species

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Iltovirus is a genus of viruses in the order Herpesvirales, in the family Herpesviridae, in the subfamily Alphaherpesvirinae. Birds, galliform birds, psittacine birds, chickens, turkeys, and quail serve as natural hosts. There are currently only two species in this genus including the type species Gallid herpesvirus 1. Diseases associated with this genus include: acute respiratory diseases: gaHV-1: infectious laryngotracheitis; psHV-1: Pacheco's disease.[1][2]

Taxonomy

Group: dsDNA

[2]

Structure

Viruses in Iltovirus are enveloped, with icosahedral, Spherical to pleomorphic, and Round geometries, and T=16 symmetry. The diameter is around 120-200 nm. Genomes are linear and non-segmented, around 150kb in length. [1]

Genus Structure Symmetry Capsid Genomic Arrangement Genomic Segmentation
Iltovirus Spherical Pleomorphic T=16 Enveloped Linear Monopartite

Life Cycle

Viral replication is nuclear, and is lysogenic. Entry into the host cell is achieved by attachment of the viral gB, gC, gD and gH proteins to host receptors, which mediates endocytosis. Replication follows the dsDNA bidirectional replication model. DNA-templated transcription, with some alternative splicing mechanism is the method of transcription. The virus exits the host cell by nuclear egress, and budding. Birds, galliform birds, psittacine birds, chickens, turkeys, and quail serve as the natural host. Transmission routes are contact, contamination, and air borne particles.[1]

Genus Host Details Tissue Tropism Entry Details Release Details Replication Site Assembly Site Transmission
Iltovirus Birds: galliform: psittacine None Cell receptor endocytosis Budding Nucleus Nucleus Oral-fecal; aerosol

References

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External Links

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