PDLIM5

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Lua error in Module:Infobox_gene at line 33: attempt to index field 'wikibase' (a nil value). PDZ and LIM domain protein 5 is a protein that in humans is encoded by the PDLIM5 gene.[1][2]

The protein encoded by this gene is a LIM domain protein. LIM domains are cysteine-rich double zinc fingers composed of 50 to 60 amino acids that are involved in protein-protein interactions. LIM domain-containing proteins are scaffolds for the formation of multiprotein complexes. The proteins are involved in cytoskeleton organization, cell lineage specification, organ development, and oncogenesis. The encoded protein is also a member of the Enigma class of proteins, a family of proteins that possess a 100-amino acid PDZ domain in the N terminus and 1 to 3 LIM domains in the C terminus. Multiple transcript variants encoding different isoforms have been found for this gene, although not all of them have been fully characterized.[2]

Interactions

PDLIM5 has been shown to interact with PRKCB1.[3]

References

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Further reading

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