Prazitone

Prazitone

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Systematic (IUPAC) name
5-phenyl-5-(piperidin-2-ylmethyl)pyrimidine-2,4,6(1H,3H,5H)-trione
Identifiers
CAS Number	2409-26-9 Y
ATC code	none
PubChem	CID: 3050417
ChemSpider	2312482 N
UNII	6DZB018428 Y
Synonyms	5-phenyl-5-(2-piperidylmethyl)barbituric acid
Chemical data
Formula	C16H19N3O3
Molecular mass	301.34 g/mol
SMILES C1CCNC(C1)CC2(C(=O)NC(=O)NC2=O)C3=CC=CC=C3
InChI InChI=1S/C16H19N3O3/c20-13-16(11-6-2-1-3-7-11,14(21)19-15(22)18-13)10-12-8-4-5-9-17-12/h1-3,6-7,12,17H,4-5,8-10H2,(H2,18,19,20,21,22) N Key:UGZAKKMLMJITLL-UHFFFAOYSA-N N
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Prazitone (AGN-511) is a barbiturate derivative developed in the 1970s. Unlike most barbiturates, it has little or no sedative effects, instead acting as a non-sedating anxiolytic and antidepressant. The dosage range in humans is around 200–600 mg, although higher doses have been used in trials for the treatment of depression associated with Parkinson's disease.