SB-242084

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SB-242084
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Systematic (IUPAC) name
6-chloro-5-methyl-N-{6-[(2-methylpyridin-3-yl)oxy]pyridin-3-yl}indoline-1-carboxamide
Identifiers
CAS Number 181632-25-7
PubChem CID: 3644637
IUPHAR/BPS 193
ChEMBL CHEMBL14563
Chemical data
Formula C21H19ClN4O2
Molecular mass 394.853 g/mol
  • Cc1cc2CCN(c2cc1Cl)C(=O)Nc(cc4)cnc4Oc3cccnc3C

SB-242084 is a psychoactive drug and research chemical which acts as a selective antagonist for the 5HT2C receptor.[1] It has anxiolytic effects,[2] and enhances dopamine signalling in the limbic system,[3] as well as having complex effects on the dopamine release produced by cocaine, increasing it in some brain regions[4][5] but reducing it in others.[6][7] It has been shown to increase the effectiveness of the selective serotonin reuptake inhibitor (SSRI) class of antidepressants, and may also reduce their side effects.[8][9] In animal studies, SB-242084 produced stimulant-type activity and reinforcing effects, somewhat similar to but much weaker than cocaine or amphetamines.[10]

See also

References

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  10. ↑ Lua error in package.lua at line 80: module 'strict' not found.



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