TSEN15

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TSEN15 tRNA splicing endonuclease subunit
250px
PDB rendering based on 2gw6.
Available structures
PDB Ortholog search: PDBe, RCSB
Identifiers
Symbols TSEN15 ; C1orf19; sen15
External IDs OMIM608756 HomoloGene12002 GeneCards: TSEN15 Gene
Orthologs
Species Human Mouse
Entrez 116461 66637
Ensembl ENSG00000198860 ENSMUSG00000014980
UniProt Q8WW01 Q8R3W5
RefSeq (mRNA) NM_001127394 NM_025677
RefSeq (protein) NP_001120866 NP_079953
Location (UCSC) Chr 1:
184.05 – 184.07 Mb
Chr 1:
152.37 – 152.39 Mb
PubMed search [1] [2]

tRNA-splicing endonuclease subunit Sen15 is an enzyme that in humans is encoded by the TSEN15 gene.[1][2][3]

tRNA splicing is a fundamental process for cell growth and division. SEN15 is a subunit of the tRNA splicing endonuclease, which catalyzes the removal of introns, the first step in tRNA splicing (Paushkin et al., 2004).[supplied by OMIM][3]

Interactions

C1orf19 has been shown to interact with TSEN2.[4]

References

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Further reading

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