DRUG STUDY

MEDICATION DRUG INDICATION / MECHANISM DOSING & ADVERSE NURSING

CLASSIFICATION CONTRAINDICATION OF ACTION ADMINISTRATION EFFECTS RESPONSIBILITIES
ibuprofen Non-steroidal anti- Indications: Inhibits tablet: CNS: Assess for allergy to
(Idyll, Motrin) inflammatory drug prostaglandin 400 mg PO q4-6 hrs. Headache drug, other NSAIDs,
-Relief of signs and synthesis by (*for mild to moderate Dizziness salicylates, and existing
Non-narcotic symptoms of rheumatoid decreasing the pain) Somnolence cardiovascular, GI, renal,
analgesic arthritis activity of the Insomnia. fatigue or hepatic disorders.
-Relief of mild to enzyme, cyclo- Tinnitus
moderate pain oxygenase, which Ophthalmologic Administer drug with
-Treatment of primary results in effects food or meals if GI upset
dysmenorrhea decreased occurs.
-Fever reduction formation of Respiratory:
prostaglandin Dyspnea, rhinitis Arrange for periodic
Contraindications: precursors. Hemoptysis ophthalmologic
Pharyngitis examination for long-
-Contrainidicated with Bronchospasm term drug use.
allergy to ibuprofen,
NSAID, salicylates CV: Discontinue drug if eye
(common in patiets with Hypertension changes, symptoms of
asthma, rhinitis, chronic Palpitations liver dysfunction or renal
urticaria, and nasal Arrhythmia impairment occur.
polyps)
-To be used cautiously Hematologic: Instruct patient to use
with hypertension, GI Bleeding the drug as suggested
bleeding, peptic ulcer, Platelet inhibition and to avoid over-the-
impaired renal or hepatic in higher doses counter medications
function, pregnancy, or Neutropenia (many OTC drugs contain
lactation. Leukpenia similar components
Pancytopenia which may lead to
Thrombocytopenia overdose).
Agranulocytosis
Aplactic anemia Instruct patient to report
Decreased Hgb and mouth sores, fever,
Hct chills, weight gain,
changes in vision,
Dermatologic: swelling in ankles or
Rash, pruritus fingers, and black, tarry
Sweating stools.
Dry mucous
membranes Instruct patient to limit
Stomatitis activities to those that
do not require alertness
and precision.

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 GI:
Nausea, dyspepsia
GI pain, diarrhea
Vomiting,
Constipation
GI bleeding
Flatulence

GU:
Dysuria, renal
impairment
Menorrhagia

Others:
Peripheral edema
Anaphylactoid
reactions to
anaphylactic
shock

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