Counter 19 Service Manual
Counter 19 Service Manual
Counter 19 Service Manual
2003-2005 Shenzhen Mindray Bio-medical Electronics Co., Ltd. Reserved. For this Service Manual, the issued Date is 2005-10 (Version: 1.0).
All rights
Release, amendment, reproduction, distribution, rent, adaption and translation of this manual in any manner whatsoever without the written permission of Mindray is strictly forbidden.
are the registered trademarks or trademarks owned by Mindray in China and other countries. All other trademarks that appear in this manual are used only for editorial purposes without the intention of improperly using them. They are the property of their respective owners.
Mindray is responsible for safety, reliability and performance of this product only in the condition that:
all installation operations, expansions, changes, modifications and repairs of this product
are conducted by Mindray authorized personnel;
the electrical installation of the relevant room complies with the applicable national and
local requirements;
Note
This equipment is not intended for family usage. This equipment must be operated by skilled/trained medical professionals.
Warning
It is important for the hospital or organization that employs this equipment to carry out a reasonable service/maintenance plan. Neglect of this may result in machine breakdown or injury of human health.
II
Warranty
THIS WARRANTY IS EXCLUSIVE AND IS IN LIEU OF ALL OTHER WARRANTIES, EXPRESSED OR IMPLIED, INCLUDING WARRANTIES OF MERCHANTABILITY OR FITNESS FOR ANY PARTICULAR PURPOSE.
Exemptions
Mindray's obligation or liability under this warranty does not include any transportation or other charges or liability for direct, indirect or consequential damages or delay resulting from the improper use or application of the product or the use of parts or accessories not approved by Mindray or repairs by people other than Mindray authorized personnel. This warranty shall not extend to: any Mindray product which has been subjected to misuse, negligence or accident; any Mindray product from which Mindray's original serial number tag or product identification markings have been altered or removed; any product of any other manufacturer. Safety, Reliability and Performance Mindray is not responsible for the effects on safety, reliability and performance of 3003 plus
III
Return Policy
Return Procedure
In the event that it becomes necessary to return this product or part of this product to Mindray, the following procedure should be followed: 1. Obtain return authorization: Contact the Mindray Service Department and obtain a Customer Service Authorization (Mindray) number. The Mindray number must appear on the outside of the shipping container. Returned shipments will not be accepted if the Mindray number is not clearly visible. Please provide the model number, serial number, and a brief description of the reason for return. 2. Freight policy: The customer is responsible for freight charges when this product is shipped to Mindray for service (this includes customs charges).
3.
Return address: Please send the part(s) or equipment to the address offered by
Company Contact Manufacture: Address: Shenzhen Mindray Bio-Medical Electronics Co., Ltd.
Mindray Building, Keji 12th Road South, Hi-tech Industrial Park, Nanshan, Shenzhen, P.R.China,518057 Phone: Fax: +86 755 26582479 26582888 +86 755 26582500 26582501
Authorized Representative Name: Address: Phone: Fax: Shanghai International Holding Corp. GmbH (Europe) Eiffestrae 80 D-20537 Hamburg Germany +49 40 2513175 +49 40 255726
IV
Content
CHAPTER 1 HARDWARE INTRODUCTION...........................................................................1 1.1 1.2 1.3 1.4 POSITION OF ELECTRONIC UNIT ................................................................................1 POSITION AND FUNCTION OF THE VOLUMETRIC UNIT ...............................................2 POWER SUPPLY UNIT .................................................................................................2 PANELS ......................................................................................................................3
2.1.2 POWER SUPPLY .........................................................................................................................3 2.1.3RTC ...........................................................................................................................................4 2.1.4CPU AND PERIPHERAL DEVICES ...............................................................................................5 2.2. ANALOG BOARD ......................................................................................................10
2.2.1OVERVIEW ...............................................................................................................................10 2.3 2.4 2.5 2.6 DRIVE BOARD..........................................................................................................15 VOLUMETRIC UNIT ..................................................................................................20 KEYPAD ...................................................................................................................21 LCD ADAPTER ........................................................................................................22
CHAPTER 3 DISASSEMBLE/REPLACE PARTS AND COMPONENTS ..............................1 3.1 3.2 SYSTEM STRUCTURE .................................................................................................1 DISASSEMBLE MAIN UNIT .........................................................................................6
CHAPTER 4 FLUIDIC SYSTEM.................................................................................................1 4.1 4.2 4.3 CHANGE INTRODUCTION ...........................................................................................1 INTRODUCTION OF BASIC TIMING .............................................................................1 TIMING ......................................................................................................................3
CHAPTER 5 HISTOGRAMS AND PULSE GRAPHS...............................................................1 5.1 5.2 HISTOGRAMS .............................................................................................................1 PULSE GRAPHS ..........................................................................................................4
CHAPTER 6 MAINTAINING YOUR ANALYZER....................................................................1 6.1GENERAL GUIDELINES..................................................................................................................1 CHAPTER 7 TROUBLESHOOTING ..........................................................................................1 7.1 7.2 7.3 ERROR CODES ...........................................................................................................1 SOFTWARE ERROR......................................................................................................2 SOLUTION ..................................................................................................................2
I
CHAPTER 8 PASSWORD.............................................................................................................1 APPENDIX SPARE PART LIST................................................................................................... I LIQUID SYSTEM DIAGRAM ....................................................................................................... I
II
Hardware Introduction
Analog board
CPU board
Figure 1-1 Inside left of the analyzer The boards are fixed directly by screws. The drive board is fixed with 6 M3 screws, while both the CPU board and analog board are fixed with 4 M3 screws respectively. The drive board is 1.5MM away from the CPU board and analog board, which are separated by about 2MM.
1-1
Hardware Introduction
Grounding pole
Hardware Introduction
1.4 Panels
Panels consist of main user interfaces, such as recorder unit (recorder drive board), keypad, indicator board and screen unit (LCD, inverter and LCD Adepter), as shown in figure 1-4: LCD Inverter LCD Adepter
Recorder module
Keypad
Indicate board
Figure 1-4 Panels disassembly view The serial signal lines, +5V and +12V power lines, the 5V ground line and the power ground are directed from the same connector of the CPU board. They are connected to the front panel by one cable and then split respectively to the recorder and the keypad. The LCD signal line is isolated. The inverter, powered by keypad power supply, drives the backlight of LCD. The backlight brightness can be adjusted via keypad. An LCD adapter is added here.
1-3
Haredware
Chapter 2 Hardware
2.1 CPU board
2.1.1 General 2.1.1.1Schematic
The CPU, FPGA and Super I/O are the major components on the board. The CPU carries out the instructions and functions as the core of the board. The FPGA functions as the relay between the CPU and the Super IO. The Super I/O includes various interfaces that can be accessed by the CPU through the FPGA. System memories are SDRAMs. The DOM is a Disk-On-Module that stores the system software and test data. The RTC is a real time clock. System configurations are stored in the EEPROM. The VRAM is the memory for video display.
2-1
Hardware
aperture voltage vacuum/pressure signals, etc. 2. To monitor such system status as the +48V, +12V and -12V supplies of the analog board, the +3.3V and +12V supplies of the CPU board itself and the temperature of the whole analyzer. 3. To receive the keypad signal and control the keypad buzzer and LCD backlight. 4. To generate control signals to control the valves, aperture zapping, HGB LED, current source and digital pot. 5. To drive and turn on the LCD and adjust the contrast. 6. To drive the keyboard, printer and floppy drive.
2-2
Hardware
2-3
Hardware
2.1.3RTC
The X1, X4 and X2 are external crystal oscillators whose frequencies are 45MHz, 45MHz and 24MHz respectively. The clock output of the CPU, BCLKO, is main clock signal of the CPU board.
2-4
Hardware
The CPU is MOTOROLA MCF5307 (external frequency 45MHz; operation frequency 90MHz; processing speed as high as 75MIPS). The MCF5307 features a 32-bit data bus and a 32-bit address bus. The board uses a 24-bit addressing mode, reserving the most-significant 8 bits as the general purpose I/Os for the FPGA. The MCF5307 can be tuned through the BDM port (J18 of the CPU board). The CPU board utilizes the built-in I2C and UART controllers of the MCF5307 to use the EEPROM and RTC as expanded serials ports. The CPU boards utilizes the built-in DRMA controller of the MCF5307 to use the 28M SDRAM as the expanded memory.
2.1.4.1WDT
The Watch-Dog-Timer (WDT) is TI TPS3828. It monitors the running of the software. The CPU must send a feedback to the WDT every 1.6s, otherwise the WDT will force the CPU to restart.
2-5
Hardware
2.1.4.2FLASH
The FLASH is TE28F160(2M bytes) . The boot program is stored in the FLASH, so the FLASH is also called the BootROM. Every time the system is powered on, the CPU first executes the boot program that initializes the system and loads the control software from the DOM. The FLASH also contains such information as
2.1.4.3SDRAM
The system memory consists of two 8M memories.
2.1.4.4DOM
The CPU board uses a 32M DOM that is powered by a 3.3V supply (the DOM can also be supplied by 5V supply). The DOM is only operational after the FPGA is configured.
2.1.4.5RTC
The CPU board uses a real time clock (RTC) to record the time. The RTC is connected to the I2C bus of the CPU board and synchronized by a 32.768KHz crystal oscillator. When the analyzer is powered on, the RTC is powered by the CPU board; when the analyzer is powered off, it is powered by the built-in battery.
2.1.4.6EEPROM
The CPU board uses an 8K EEPROM to store such information as system configurations and settings. It is connected to the I2C bus of the CPU and can be written by CPU on-line.
2-6 Auto Hematology Analyzer Service Manual (V1.0)
Hardware
2.1.4.7LEDs
When D1 is on, it means +3.3V is functioning properly. When D9 is on, it means +12.8V is functioning properly. When D5 is on, it means the system is reading
or writing the DOM. When D7 is on, it means the FPGA has been configured and is functioning properly. When D20 is on, it means the FPGA is restarting; The D11D18 indicate the system status as defined by the software.
Test Points
Position No. TP1 AVCC +12V input TP2 CLK0 Main clock 0 analog Input through J1.31/33 and then supplied by the analog board Frequency 45MHz; reference clock; affecting the whole board TP3 CLK1 Main clock 1 Frequency 45MHz, affecting the FPGA and all the devices connected to it TP4 TP5 TP6 TP7 TP8 TP9 TP10 CLK2 CLK3 CLK4 GND AVDD AGND VCC Main clock 2 Main clock 3 Main clock 4 Digital ground +5V analog input Analog ground +5V digital On the condition of normal AVCC input Same potential as the digital ground Frequency 45MHz, affecting the LCD buffering Frequency 45MHz, affecting the SDRAM Frequency 45MHz, affecting the SDRAM Mark Test Point Description
power supply TP12 TP13 TP14 TP15 GND GND GND AOUT Digital ground Digital ground Digital ground PWM output Set through the software and not used currently. TP16 XCK LCD shift clock Frequency 9MHz, ensuring the LCD works normally TP17 DISCLK Oscillation Frequency 45MHz, affecting the LCD and A/D
2-7
Hardware
conversion Frequency 30MHz, ensuring the Super I/O can be accessed correctly
TP19
SIOCLK
Oscillation frequency X2
TP20
RTCCLK
Oscillation frequency X3
Frequency 32.768KHz, affecting the real-time clock Special power supply for the FPGA, ensuring the FPGA works normally Not used for this board, isolated from other power supply of this board and supplied to the recorder and keypad, affecting the recorder, buzzer and backlight of the LCD
TP21
VDDC
+1.5V
digital
TP23 TP24
G+12 HGB
Ground of the +12.8 power supply Input to the A/D of this board, marked H on the PCB
TP25
RBC
RBC signal
analog
TP26
WBC
WBC signal
analog
TP27
PLT
PLT signal
analog
TP28
VREF
A/D voltage
reference
Hardware
The CPU incorporates 2 UART controllers (3.3LVTTL), one to control the motor of the driving board and the other communicates with the recorder (powered by 5VTTL). The FPGA implements 2 UART (3.3VTTL), one to connect the keypad
and the other reserved to control the pump. Another 2 UARTs (RS232) are implemented inside the Super I/O to connect the scanner and to communicate with the PC.
Hardware
2.1.6.3GPIOs
1 Signals of the Start key The FPGA detects the input signal, which will turn low when the Start key is pressed. 2 Volumetric metering Signals The FPGA detects the signals sent by the start transducer and the end transducer. 3 Signals of level detection The BC-2800 has not level sensors 4 Digital pot The SPI bus interface implemented by the FPGA controls the 4 digital potential-meters on the analog board to control the HGB gain. 5 Signals controlling valves and pumps The Super I/O outputs 20 control signals to control the valves and pumps through the driving board. Since the BC-2800 only has 1 pump and 11 valves, the redundant lines and ports are reserved. 6 Signals controlling bath The Super I/O outputs 4 control signals (through the analog board) to control the three switches that respectively control the aperture zapping, current source and HGB LED. 7. Others The Super I/O outputs 2 control signals to control the photo-couplers of the volumetric metering board and the buzzer of the keypad.
2-10
Hardware
2-11
Hardware
Hardware
Hardware
11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34
AGND NC AGND AGND PLT AGND RBC AGND WBC AGND HGB AGND PRESSURE AGND VACUUM AGND WBC-HOLE AGND -12VA-MON +56V-MON RBC-HOLE +12VA +12VA-MON +12VA
Analog ground Analog ground Analog ground PLT Analog ground RBC Analog ground WBC Analog ground HGB Analog ground Pressure Analog ground Vacuum Analog ground WBC aperture voltage Analog ground -12V analog power supply detection +48V analog power supply detection RBC aperture voltage 12V analog power supply +12V analog power supply detection 12V analog power supply
TP6 TP7
2-14
0-5V 3V3%
Hardware
TP8 TP9 TP10 TP11 TP12 TP13 TP14 TP15 TP16 TP17 TP18 TP19 TP20
+56VA-MON voltage monitoring point Output of the RBC amplifying channel Output of the PLT amplifying channel Output of the pressure measuring circuit Output of the vacuum measuring circuit Detection of the consistent current for the vacuum pressure unit 2.5V output AVCC power supply test point +5V power supply AVSS power supply test point +100V test point AGND Test point 2 where the HGB circuit supplies consistent current for the LED
2.2 V3% 0-5V 0-5V 0-5V 0-5V 2.5V 2.5V +12V +5V -12V +100V 0V 0-5V
2.3.2.1
The power supply unit includes a 5V, 12V and 30V DC. The 12V and 30V supply comes from the power interfaces, where two LEDs are installed to respectively indicate whether the 12V or 30V supply is connected. When the LED is on, it indicates the corresponding power has been connected to the drive board. The MC7805T converts the received 12V supply into the 5V supply, as shown in the figure below.
Auto Hematology Analyzer Service Manual (V1.0) 2-15
Hardware
12V
MC7805T
5V
2.3.2.2
The switch control unit mainly consists of the photocoupler circuit and drive circuit of valves and pumps, as shown in the figure below.
Figure 2-9 Switch Control Unit Photocoupler circuit The photocoupler circuit mainly consists of the photocoupler and resistors. It provides 20 TTL outputs to the valves and pumps. The photocoupler, TLP521-2, isolates the digital ground from the power ground. Drive circuit of valves and pumps The drive voltage of the valves and pumps is 12V (TTL). The circuit mainly consists of ULN2068. In the BC-3000 Plus, the circuit can drive 18 valves and 2 pumps at most. The fluidic system decides how many pumps or valves are to be actually used.
2.3.2.3
The motor control unit includes: serial communication circuit, control/drive circuit of the sample probe mechanism, control/drive circuit of the syringe motors, and drive/signal-detecting circuit of the position sensors. Serial communication circuit Since the CPU board requires a 3.3V power supply while the drive board requires a 5V power supply, a photocoupler (H11L1) is needed for the purposes of conversion and isolation. Control/Drive circuit of the sample probe mechanism The control/drive circuit of the sample probe mechanism includes the control/drive circuit of the elevating motor and that of the rotation motor. The control system of the sample probe motor consists of an AT89S51 MCU and ADM705 WDT. The AT89S51 also detects the signals coming from the position sensor when controlling the motors.
2-16
Hardware
The MCU system provides the sequence signals for the elevating and rotation motors and controls the position sensor, as shown in the figure above. The MCU reset signal (RST_XY) is active for high level. The drive part mainly consists of a control device (L6506), drive device (L298N) and follow-current device (UC3610). The drive voltage is 30V. The sequence signal and the enabling signal of the driver come from the MCU. Control/Drive circuit of the rotation motor The circuit mainly consists of a control part (MCU system) and a drive part. Refer to the previous introduction for the MCU system. The drive part is the ULN2068B and the drive voltage is 12V. Control/Drive circuit of the Syringe Motors The circuit mainly consists of a control part (MCU system) and a drive part. The MCU is the P87LPC762 with built-in WDT. The MCU system executes the aspirating and dispensing operation of the syringes and detects the signals sent by the position sensor. The drive part is similar to that of the elevating motor. See figure 2-9 for details. Drive/Signal-detecting Circuit of the Position Sensor The control system judges the motor positions by the signals sent by the position sensor (photocoupler). The photocoupler is driven by the MCU through a 74LS07 and sends the position signals to the MCU through a 74LS14 (inverter). See the figure below for the position-detecting circuit. The photocoupler is installed on the sample probe assembly or syringe assembly and feeds the control and feedback signals to the drive board through cables.
2.3.3 Interfaces
2.3.3.1
Pin 1 3
2-17
Hardware
L1_BLUE
L1_BLUE
2-18
Hardware
1 3 5
803_D
Terminal 1 of phase voltage 1 Terminal 2 of phase voltage 1 12V power supply (phase voltage 2)
2 4 6
12V power supply (phase voltage 1) Terminal 1 of phase voltage 2 Terminal 2 of phase voltage 2
803_C +12VP
851_B
8 SK2 10 12 14 SD4 16 18 20 22
P1_851 PGND
SK4 P_L2 PGND SD6 Up position of the 50L syringe motor Power ground Enable the photocoupler of the 50L syringe motor Drive the photocoupler of the 50L syringe motor
2-19
23
SK5
24
SK6
Hardware
25
NC
Reserved
26
NC
Reserved
+12VP
2.4.2 Circuit
Test point P1 is PGND and P2 is ZR431 output (2.5V). The consistent current can be checked by testing the voltage of P2 for P1. Moreover, the consistent-current switch is controlled by Q1. The jumper TX1 debugs and tests the analog signals CTRL-CNT. The consistent current can be switched on/off manually.
2-20 Auto Hematology Analyzer Service Manual (V1.0)
Hardware
In the circuit, a 10K pot is in serial connection with a 220 resistor for I/V conversion. The pot can be adjusted in background status (no obstacle between sending and receiving of the photocoupler) to set the voltage of P3 to 3V. Therefore, the voltage of P3 is above 2.7V or below 2.3V when there is or no fluid in the metering tube. The WBC-STAR outputs low level (LED D1 on) or high level (LED D1 off) accordingly.
2.4.3 Interface
The volumetric unit has one interface to the CPU board, as shown in the figure below:
VCC WBC-START DGND WBC-STOP RBC-START PGND RBC-STOP VPP CTRL-CNT 1 2 3 4 5 6 7 8 9
2.5 Keypad
2.5.1 Functions
To scan the keypad The keypad adapter scans the keypad and reports the scanned key code to the main board. To control the LCD brightness The keypad adapter receives instructions from the main board to turn on/off the backlight and power indicators of the LCD and to control the brightness of the backlight. To control the buzzer The keypad adapter receives instructions from the main board to turn on/off the buzzer.
Hardware
program: carry out the current instruction (switch the LCD backlight, switch the buzzer); scan the keyboard; report the scanned key code to the main board when there is button pressed. Manage the serial communication interference to receive the instructions come from the main board.
2-22
Hardware
2-23
Chapter
Disassemble/Replace
Parts
and
Components
3.1 System Structure
3.1.1 User Interfaces
3-1
1 --- RS-232 Port1 3 --- RS-232 Port2 5 --- Power Interface of Floppy Disk Drive 7 --- Diluent inlet 9 --- Rinse sensor connector 11 --- Rinse inlet 13--- Equipotentiality
2 --- Parallel Port 4 --- Keyboard interface 6 --- Safety labeling 8 --- Diluent sensor connector 10 --- Waste outlet 12--- Power switch 14--- WEEE labeling
3-2
1 2 3 4 5 6
1 --- Elevator motor 3 --- Probe wipe 5 --- RBC shielding box
2 --- Sample probe 4 --- WBC shielding box 6 --- Aspirate key
3-3
0 2
1 --- Valve8 3 --- Vacuum chamber 5 --- Valve14 7 --- Valve11 9 --- Valve2 11 --- 50ul and 2.5ml motor 13 --- 2.5ml syringe 15 --- 10ml syringe 17 --- Valve4 19 --- Valve1 21 --- Valve15 23 --- Valve17 25 --- Valve18
1 2 3 4 5 6 7 9 0 1 1 1
8 1 7 1 6 1 5 1 4 1 3 1 2 1
Figure3-4 Inside right of the analyzer 2 --- Volumetric metering unit 4 --- Valve13 6 --- Valve12 8 --- Valve10 10 --- Valve9 12 --- 10ml motor 14 --- 50ul syringe 16 --- Valve6 18 --- Valve3 20 --- Valve5 22 --- Valve16 24 --- Valve7
3-4
3-5
Figure 36
Figure 37
3-6 Auto Hematology Analyzer Service Manual (V1.0)
to remove valves (total 18 valves). 2) remove the syringe assembly, remove 4 screws indicated by the arrow with cross screw driver to remove the syringe assembly. 3) remove the vacuum assembly, remove 2 screws indicated by the arrow with cross screw driver to remove the vacuum assembly. 4) remove the volumetric assembly, Remove the fixing screw on the
shielding box of the volumetric assembly,open the shielding box, remove 2 screws indicated by the arrow with cross screw driver and wrench to remove the volumetric assembly.
Figure 38
3.2.4
as shown in figure open panel assembly and remove screws(total 7 screws) indicated by the arrow with cross screw driver to replace LCD screen.
3-7
Figure 39
Figure 310
remove LCD.
3-8
Figure 311
Figure 312
3-9
Figure 313
3.2.9
as shown in figure 1 Replace pressure Chamberremove 2 screws indicated by the arrow with cross screw driver to remove pressure Chamber. 2 Replace pumpremove 2 nuts and 2 screws indicated by the arrow with wrench and screw driver
Figure 31
3-10
Figure 315
Figure 316
3-11
Figure 317
Figure 318
Figure 319
Figure 320
3-12
Figure 321
Figure 322
Figure 323
Auto Hematology Analyzer Service Manual (V1.0) 3-13
1.
Remove the fixing screw on the shielding box of the RBC bath (see figure 3-24). Then remove the shielding box. Take out the RBC bath assembly from the clips (see figure 3-25). Pull off the tubing connected to the RBC bath and disconnect the connector of the RBC bath inside the enclosure; remove the RBC bath assembly. Use a nipper to remove the RBC/PLT aperture. Remove the two screws and then take out the aperture between two washers (see figure 3-26 through 3-27). Please note that you should replace the tubing connected to the metal junction when placing the count bath.
Figure 324
Figure 325
3-14
Figure 326
Figure 327
2.
It is similar to removing the RBC bath (see figure 3-28 through 3-29). As the difference between the configurations of the two baths, remove the two black plastic objects as shown in figure 3-30 prior to carry out the action as shown in figure 3-27.
Figure 328
Auto Hematology Analyzer Service Manual (V1.0)
Figure 329
3-15
Figure 330
3-16
3-1
Fluidic System
Fluidic System
controlled by command in the timing, and the other is to be controlled directly with the valve 10 opened and the waste pump starts working. When counting, the vacuum pressure must be -24kPa. 3. To establish pressure: Pressure can be established by starting the pressure pump. The pressure value can be controlled in two ways, one is to be controlled by command in the timing, and the other is to be controlled directly with the pressure pump started. Pressure is used to pump bubbles into baths for mixing the sample and to increase the pressure in vacuum chamber to flush the aperture. To do this, the pressure pump is started and valve 9 is opened. 4. To aspirate diluent: Via 10mL syringe, diluent is aspirated. 5. To dispense diluent: Via 10mL syringe and valve 3 is opened, diluent will be dispensed into the WBC bath, RBC bath or to the probe wipe. 6. To dispense diluent to the probe wipe: When diluent is dispensed into the WBC bath or RBC bath, valve 1 is opened simultaneously and diluent is dispensed to the probe wipe. 7. To dispense diluent to the sample probe: To dispense diluent to the sample probe, valve 4 is opened simultaneously so that diluent is dispensed into the sample probe. 8. To dispense diluent to the RBC bath: To dispense diluent to the RBC bath, valve 5 is opened simultaneously so that diluent is dispensed into the RBC bath. 9. To aspirate lyse: Via 2.5mL syringe, lyse is aspirated. 10. To dispense lyse: Via 2.5mL syringe and valve 6 opened, lyse is dispensed into the WBC bath. 11. To empty RBC bath: with the waste pump started and valve 11 opened, the RBC bath is emptied. 12. To empty WBC bath: with the waste pump started and valve 12 opened, the WBC bath is emptied. 13. To pump air into the RBC bath: A certain pressure should be established in the pressure chamber via system command, then valve 15 is opened and the air in the pressure chamber can be pumped into the RBC bath. 14. To pump air into the WBC bath: A certain pressure should be established in the pressure chamber via system command, then valve 16 is opened and the air in the pressure chamber can be pumped into the WBC bath. 15. To aspirate the sample: Via 50mL syringe, the sample is aspirated into the sample probe. 16. To dispense the sample: Via 10mL syringe and valve 4 opened, sample is
4-2
Fluidic System
dispensed from the sample probe. At the same time, a little diluent is dispensed too. 17. To empty the RBC metering tube: After vacuum is established, valve 17 is opened to empty the RBC metering tube. 18. To count in the RBC metering tube: After the RBC metering tube is emptied and vacuum is established, valve 18 is opened and the counting is started. 19. To empty the WBC metering tube: After vacuum is established, valve 7 is opened to empty the WBC metering tube. 20. To count in the WBC metering tube: After the WBC metering tube is emptied and vacuum is established, valve 8 is opened and the counting is started. 21. To clean the RBC back bath and the RBC metering tube: After vacuum is established, valve 13 and valve 18 are opened so that rinse can pass from the RBC back bath and the RBC metering tube and then to the vacuum chamber. 22. To clean the WBC back bath and the WBC metering tube: After vacuum is established, valve 14 and valve 8 are opened so that rinse can pass from the WBC back bath and the WBC metering tube and then to the vacuum chamber.
4.3 Timing
4.3.1 Timing for Dispensing Prediluent
1. In the predilute mode, press the DILUENT key on the keypad to enter the timing for dispensing prediluent. 2. 0.7mL diluent should be dispensed from the sample probe by pressing the START key every time. 3. You can repeat the operations above. 4. Press the ENTER key on the keypad to exit the timing.
4-3
Fluidic System
Fluidic System
11 Sample and the second dilution are mixed by pumping bubbles into the bath. 12 The 50L syringe is replaced before the end of the timing. Timing Flow Chart
4-5
Fluidic System
4-6
Fluidic System
4-7
Fluidic System
so that the flow rate of WBC metering tube is faster than that of RBC). Timing Flow Chart
4-8
Fluidic System
4-9
Figure 5-1
NOTE
Blood cells lain between the first and the second discriminators are lymphocyte; those between the second and the third discriminators are mid-sized cells; those between the third and the fourth discriminators are granulocyte. The fourth discriminator is the fixed line. 2. No differential result because the WBC histogram is over-narrowly compressed.
Figure 5-2
3.
No differential result because WBC count result is less than a certain value (WBC < 0.5).
Figure 5-3
5-1
4.
No differential result because the peak of WBC histogram lies in the middle of the histogram and thus cannot identify the type of peak cells.
Figure 5-5 6. Severe interference in WBC channel (identifying if it is interfered by observing the pulse graph)
Figure 5-8
5-2 Auto Hematology Analyzer Service Manual (V1.0)
9.
Increased lymphocytes
Figure 5-11
5-3
Data length of abnormal sample will not lie in this range. Length of normal level controls data should be: WBC400 ~ 700K RBC250 ~ 450K PLT300 ~ 600K
5.2.1
5-4
5-5
Figure 5-17
5.2.2
Figure 5-18
5-6
Figure 5-19 Severe interference in RBC channel Data length increases obviously (background)
Figure 5-20 Severe interference in RBC channel Data length increases obviously (normal sample)
Figure 5-21 Severe interference in PLT channel Data length increases obviously (background)
Auto Hematology Analyzer Service Manual (V1.0) 5-7
Figure 5-22 Severe interference in PLT channel Data length increases obviously (normal sample)
Figure 5-23 Interference occurs because gain of PLT channel is too large Data length increases (background count)
Figure 5-24 Interference occurs because gain of PLT channel is too large Data length increases (normal sample)
5-8 Auto Hematology Analyzer Service Manual (V1.0)
Figure 5-25 Slight interference in WBC channel Data length does not increase obviously (normal sample)
Figure 5-27
Slight interference in RBC channel Data length does not increase obviously (normal sample)
Auto Hematology Analyzer Service Manual (V1.0) 5-9
Figure 5-28 Sample of too dense concentration in RBC channel (Does not occur in normal situation)
Figure 5-29 Slight interference in PLT channel Data length does not increase obviously (normal sample)
Figure 5-30
Sample of too dense concentration in PLT channel(Does not occur in normal situation)
5-10
Figure 5-31 Interference in WBC channel caused by inverter Feature: sine wave with cycle of 2026us
Figure 5-33
5-11
Figure 5-34 Interference in RBC channel from tubing Feature: data length increases, the base line of signal is not stabile.
Figure 5-36
Interference in PLT channel from tubing Feature: data length increases, the base line of signal is not stabile.
5-12 Auto Hematology Analyzer Service Manual (V1.0)
Figure 5-38 Interference in WBC channel from tubing Feature: data length increases, the base line of signal is not stabile.
Figure 5-39
5-13
Content of Maintenance If you are to use this analyzer 24 hours a day, be sure to perform the E-Z cleanser cleaning procedure everyday. Run the QC program everyday. See Operation manual chap QC for details.
If you are to use this analyzer 24 hours a day, be sure to perform the Probe cleanser cleaning procedure every three days.
Every Week
If you shut down your analyzer every day and follow the specified shutdown procedure to do that, you need to perform the Probe cleanser cleaning procedure every week.
Every Month
You should use the supplied probe localizer to calibrate the position of the probe to that of the probe wipe. The analysis result is sensitive to their alignment.
As needed
When you think the baths might be contaminated, perform the Clean the baths procedure. When the analyzed whole blood samples add up to 300 or prediluted samples add up to 150, the analyzer will remind you to perform the Probe cleanser cleaning procedure. When the analyzed whole blood samples add up to 2,000 or prediluted samples add up to 4,000, the analyzer will remind you to perform the Clean wipe block procedure. When this analyzer is not to be used for two weeks, be sure to perform the Prepare to ship procedure to empty and wash the fluidic lines and then wipe the analyzer dry and wrap it up for storage. To obtain reliable analysis results, this analyzer needs to work in a normal status. Be sure to run the System Test items regularly to check the status of this analyzer.
6-1
When this analyzer gives alarms for clogging, you can perform the Flush Apertures or Zap Apertures procedure, or press [FLUSH] to unclog the apertures. If you see other error messages, see operation manual chap troubleshooting, for solutions.
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Chapter 7 Troubleshooting
Chapter 7 Troubleshooting
7.1 Error Codes
Table 7-1 Errors and codes
Code
Error Environmental
Code
Code
Error
0x0401
0x0402
0x0403 0x0406
HGB error
0x0404 0x0407
0x0405 0x0408
WBC bubble
0x0801
error
out
of
0x1002
0x1004
0x1005
Recorder hot
too
0x1006
Press bar up
0x2001
Lyse out
0x2002
Diluent expired
0x2003
0x2004
Lyse expired
0x2005
0x2006
0x4002
10ml
Syringe
0x4001
0x4004
Elevator error
motor
motor error Rotation motor error 3.3V error WBC A/D error Vacuum error Rinse out 0x400B 0x4007 0x400E 0x4008
12V
7-1
Chapter 7 Troubleshooting
0x8001
File error
0x8002
Flash error
RAM
If happens, write down thee error code and contact Mindray person Note:you may restart your unit first
7.3 Solution
See the information below for the error messages and their probable causes and recommended action. If the problem still remains after you have tried the recommended solutions, contact Mindray customer service department or your local distributor.
7-2
Chapter 7 Troubleshooting
3.
If the problem remains, shut down your analyzer and change CPU board.
3.
If the problem remains, shut down your analyzer and clean HGB unit.
Chapter 7 Troubleshooting
possible reason Clogged RBC aperture; Inappropriate RBC count time setting;
Enter the Service Maintenance screen. Zap and flush the aperture as instructed in operation manual. Enter the Setup Count Time screen and record the RBC count time. Then enter the Service System Test screen and test the actual RBC count time
If the difference between the references RBC count time and the actual RBC count
time is less than 2 seconds, the error has been removed; If not, enter the Service Maintenance screen and do the probe cleanser cleaning procedure. Enter the Setup Count Time screen and record the RBC count time. Then enter the Service System Test screen and test the actual RBC count time again: If the difference between the reference RBC count time and the actual RBC count time is less than 2 seconds, the error has been removed. If the difference is still greater than 2 seconds but consistent, enter the Setup Count Time and reset the RBC count time. Then enter the Service System Test screen and test the actual RBC count time as instructed by operation manual to confirm the
3. Inappropriate RBC
Recommended Action: 1.
7-4
Check if the diluent or rinse has run out. If so, change a new container of
Auto Hematology Analyzer Service Manual (V1.0)
Chapter 7 Troubleshooting
diluent or rinse as instructed in operation manual. 2. Check the connection of the diluent and rinse pickup tube. If necessary, reconnect and tighten them operation manual. 3. If the problem remains, adjust the RBC count time
3.
Solenoid valve error. Recommended Action: 1. Enter the Service Maintenance screen. Zap and flush the aperture as instructed in operation manual. 2. Enter the Setup Count Time screen and record the WBC count time. Then enter the Service System Test screen and test the actual WBC count time
If the difference between the references WBC count time and the actual RBC
count time is less than 2 seconds, the error has been removed; If not, enter the Service Maintenance screen and do the probe cleanser cleaning procedure.
3.
Enter the Setup Count Time screen and record the WBC count time. Then enter the Service System Test screen and test the actual WBC count time again: If the difference between the reference WBC count time and the actual WBC count time is less than 2 seconds, the error has been removed.
4.
If the difference is still greater than 2 seconds but consistent, enter the Setup Count Time and reset the WBC count time. Then enter the Service System Test screen and test the actual WBC count time as instructed by operation
Chapter 7 Troubleshooting
time is greater than 2 seconds, your analyzer will give RBC clog alarm: possible reason
1. Diluent or rinse running out; 2. Loose tube connections;
Check if the diluent or rinse has run out. If so, change a new container of diluent or rinse as instructed in operation manual.
2.
Check the connection of the diluent and rinse pickup tube. If necessary, reconnect and tighten them operation manual.
3.
3.
The tubes at the back of the analyzer are pressed. Recommended Action
1. 2. 3.
Check if the diluent is contaminated or expired; Check if the tubes connected at the back of the analyzer is pressed; Enter the Count screen and press [STARTUP] (or [F3] of the external keyboard) to do the startup procedure;
4. If the problem remains, enter the Service Maintenance screen and do the probe cleanser cleaning procedure as instructed in operation manual. When the procedure is finished, return to the Count screen and do the background check again;
Chapter 7 Troubleshooting
1. 2.
Check if the rinse has expired. If so, change a new container of rinse If not, reset the expiration date
7-7
Chapter 7 Troubleshooting
Damaged recorder. Recommended Action If the problem remains, shut down your analyzer and check the recorder module and CPU board and power supply.
7-8
Chapter 7 Troubleshooting
Recommended Action: 6. Open the front panel and check if the sample probe is jammed; 7. Enter the Service System Test screen and check the motor as instructed in operation manual. The error will be removed if the test result is normal
7-9
Chapter 7 Troubleshooting
2. Check transducer
7-10
Chapter 7 Troubleshooting
7-11
Chapter 7 Troubleshooting
2. If not, enter the Service System Test screen and check the motor as instructed in
7-12
Chapter 7 Troubleshooting
operation manual The error will be removed if the test result is normal;
Malfunctioning photo coupler Recommended Action Enter the Service System Test screen and check the motor as instructed in operation manual The error will be removed if the test result is normal.
Chapter 7 Troubleshooting
7-14
Chapter 8 Password
Chapter 8 Password
Level Password Operation menu Count Functions press[1][2][3]view WBCRBCPLT pulse graph Count Review\histogram Service 1 engineer (3210) Setup\other Service\error Setup\gain Setup Review\table Setup\other Press [] to upgrade [F5] sample information Delete sample results 1 Display and modifydelete sample results optionOn/off 2 Change language press[DEL]view configuraton press[DEL]delete error message View PLT gain (cant be changed) Adjust WBC(WH/PRE)RBCHGB gain (Counting time) counting time parameter unitparameter unit (Reference range) general/man/woman/child/ neonate 2 administrator (3000) Calibrator\manual Calibrator\auto Calibrator\fresh Service\system test Review\table delete sample results option on, delete sample results 3 user Refer to operation manual Calibrate by manual Calibrate by auto Calibrate by fresh blood Test the running status of the motor
8-1
Chapter 8 Password
8-2
Part number 3003-30-34887 TR6D-30-16659 TR6D-30-16662 3001-20-07172 3001-10-07054 3001-10-07207 3001-10-07208 3001-30-06925 3001-30-06923 3001-30-06924 3001-20-07247
Part name LCD assembly TR60-D recoder TR60-D recorder driver board Front bath clip Filter Cross screw driver Wrench CAP Component For Rinse CAP Component For Lyse CAP Component For Diluent Localizer
II
P/N1805-20-54375
V1.0