Spectrum Flows Transverse TO Axis : Flow (L)
Spectrum Flows Transverse TO Axis : Flow (L)
Spectrum Flows Transverse TO Axis : Flow (L)
Cisneros**,
B i o m e d i c a l E n g i n e e r i n g and S c i e n c e I n s t i t u t e
Drexel U n i v e r s i t y
P h i l a d e l p h i a , PA 19104
US A
ABSTRACT
T h e o r e t i c a l a n a l y s i s and e x p e r i m e n t a l r e s u l t s a r e
g i v e n f o r a Doppler method f a c i l i t a t i n g t h e
a s s e s s m e n t of f l o w p a r a m e t e r s , u s i n g a sound beam
whose a x i s is p e r p e n d i c u l a r t o t h e f l o w .
The
s i m p l i s t i c Doppler e f f e c t f o r m u l a p r e d i c t s z e r o
f r e q u e n c y s h i f t s f o r t h i s geometry. However t h e
p r e s e n t c o n f i g u r a t i o n of a f i n i t e a p e r t u r e and
f o c u s e d beam c o n t a l n s o b l i q u e r a y s which p r o v i d e
t h e d e t e c t i b l e Doppler s i g n a l s , i n s p i t e of t h e
f a c t t h a t t h e f l o w is t r a n s v e r s e w i t h r e s p e c t t o
the axis.
Using p u l s e d U l t r a s o n i c D o p p l e r , w i t h
a t r a n s d u c e r having a c i r c u l a r a p e r t u r e , i n - v i t r o
f l o w measurements have been performed, which comp a r e w e l l w i t h r e s u l t s of c l a s s i c a l t e c h n i q u e s ,
and are a l s o i n agreement w i t h t h e p r e s e n t theoretical analysis.
I.
Introduction
COS
(1)
P a r t i a l l y based on Ph.D. t h e s i s of J . A . C i s n e r o s
under t h e s u p e r v i s i o n of V.L. Newhouse, submitt e d t o t h e F a c u l t y of D r e x e l U n i v e r s i t y , 1985.
S u p p o r t e d by t h e Bessie and L o u i s S t e i n Foundation.
Supported by NSF G r a n t No. ECS-8219736.
**
***
P r e s e n t l y w i t h t h e S c h o o l of M e d i c i n e , C e n t r a l
U n i v e r s i t y o f Venezuela, and S c h o o l of Engin e e r i n g , Simon B o l i v a r U n i v e r s i t y
On l e a v e of a b s e n c e from t h e Dept. o f E l e c t r i c a l and Computer Eng., Ben Gurion U n i v e r s i t y
of t h e Negev, Beer Sheva, I s r a e l .
****
Dept. of R a d i o l o g y , D i v i s i o n of U l t r a s o u n d
and R a d i o l o g i c Imaging, Thomas J e f f e r s o n
U n i v e r s i t y H o s p i t a l , P h i l a d e l p h i a , PA 19107.
Theory
11.
I n t h e a c t u a l e x p e r i m e n t 121, 131, a t r a n s d u c e r
h a v i n g a c i r c u l a r a p e r t u r e was used. The a n a l y s i s
is however much s i m p l e r i f a two-dimensional configuration is treated.
We t h e r e f o r e begin by
c o n s i d e r i n g a ( t h e o r e t i c a l l y i n f i n i t e l y -) l o n g
s t r i p t r a n s d u c e r , o r i e n t e d a l o n g t h e y - a x i s and
e x t e n d i n g from x=F,=-w/2 t o x=F,=w/2.
C o n s i d e r an
element of w i d t h d g s i t u a t e d a t 5. T h i s is a l i n e
s o u r c e p r o d u c i n g an a c o u s t i c a l p r e s s u r e dp a t
l o c a t i o n x , y , z , where z>>W, g i v e n by
ik( r-@in
e)-i
ut
dp z Kdce
(2)
where K is a p r o p o r t i o n a l i t y f a c t o r . f = o / 2 n i s t h e
f r e q u e n c y , k=2n/X is t h e p r o p a g a t i o n v e c t o r , r2=
x&z2, and s i n 9 = x / r . F o r a t r a n s d u c e r of uniform
a p e r t u r e K i s i n d e p e n d e n t of 5, and t h e p r e s s u r e
is g i v e n by
w/2
p(r,e,t) =
dp =
-w/2
i k r - i w t W/2
f5
e - i k 5 s i n e df.
-ill2
ikr-iwt
(3)
where s i n c a = ( s i n a ) / a . A c o n v e r g i n g l e n s a d j a c e n t
t o t h e t r a n s d u c e r produces i n t h e f o c a l p l a n e
s i n B = x / F , where F i s t h e f o c a l l e n g t h .
See F i g .
1. Hence f o r r = F ( 3 ) becomes
p ( x , t ) = K'sinc(yx)e-iot,
y =
k W/2F
(4)
- 971
TRANSDUCER
LENS
w/2
Y
F i g . 1:
FOCAL
PLANE
r---
ik
'K
'-iw't
'
(9)
where K" is y e t a n o t h e r p r o p o r t i o n a l i t y f a c t o r .
By F o u r i e r t r a n s f o r m i n g ( 9 ) , i t f o l l o w s t h a t t h e
p r o f i l e of t h e s p e c t r u n c o r r e s p o n d i n g t o pt i s
t r i a n g u l a r , w i t h a maximm at w and z e r o a t
w [ l f ( v / c ) ( W / F ) ] , where 2 w(v/c)(W/F) i s t h e exp e c t e d Doppler f r e q u e n c y (1) produced and measured
by t h e t r a n s d u c e r ' s e d g e s . The s c a t t e r i n g by t h e
ensemble of p a r t i c l e s i s i n c o h e r e n t and t h e r e f o r e
t h e s p e c t r a l d e n s i t y f u n c t i o n p o s s e s s e s t h e same
s t r u c t u r e . The e x p e r i m e n t a l r e s u l t s below and
( 9 ) are in good a g r e e m e n t , in s p i t e o f t h e p r i m i t i v e model used i n t h e t h e o r e t i c a l a n a l y s i s .
The t h r e e - d i m e n s i o n a l a n a l y s i s i s much more comp l i c a t e d and w i l l be d i s c u s s e d e l s e w h e r e . EssenE s s e n t i a l l y ( 5 ) , f o r a c i r c u l a r a p e r t u r e of r a d i u s
L, ( 4 ) is r e p l a c e d by
Jl(tk9)/ik9
9 = (v2t2
+ y2)'12/F
(10)
111.
a/ Jr'
Experimental Procedures
(5)
i . e . , a r e c t a n g u l a r p r o f i l e spectrum w i t h i n t h e
l i m i t s i n d i c a t e d i n ( 6 ) . Combining (5) and ( 6 ) ,
t h e f i e l d s c a t t e r e d from a l i n e p a r t i c l e i s g i v e n
by
t ' = t-F/c
(8)
972
In o r d e r t o v e r i f y t h e t h e o r y , e x p e r i m e n t s have
been performed [ 3 ] , o b s e r v i n g a b l o o d s i m u l a t i n g
m i x t u r e , in c o n t i n u o u s flow t h r o u g h a p l a s t i c
t u b e . A s t a n d a r d commercially a v a i l a b l e u l t r a s o n i c m e d i c a l "Duplex" system h a s been used,
which c o u l d s w i t c h from imaging t o Doppler f l o w
measurements w i t h o u t changing t r a n s d u c e r p o s i t i o n .
The Duplex i n s t r u m e n t a t i o n c o n s i s t e d of a Technicare Auto S e c t o r which had a b u i l t in s p e c t r u m
analyzer. T h i s w a s operated with a mechanical
r o t a t i n g t r a n s d u c e r assembly ( p r o b e model 8106D)
c o n t a i n i n g t h r e e t r a n s d u c e r e l e m e n t s , one o f them
a Doppler o p t i m i z e r s i n g l e c r y s t a l e l e m e n t . Imagi n g w a s performed w i t h 7.5MHz, image o p t i m i z e d
s i n g l e c r y s t a l t r a n s d u c e r elements i n a r o t a t i n g
assembly d e s i g n f o r real-time s e c t o r a l imaging.
Doppler s i g n a l s were o b t a i n e d i n t h e p u l s e mode,
u s i n g a r e p e t i t i o n f r e q u e n c y of 15KHz. The Dopp l e r t r a n s d u c e r - had a c r y s t a l d i a m e t e r of llmm
and, according t o t h e manufacturer's s p e c i f i c a t i o n s , a beam e n t r a n c e d i a m e t e r of 8.5mm.
The
c e n t e r f r e q u e n c y of t h e t r a n s d u c e r was 4.55MHz,
w i t h a p e r c e n t bandwidtH of 20%, w i t h a range
c e l l of l m m l e n g t h . The f o c a l d i s t a n c e F o f t h e
t r a n s d u c e r w a s 22mm and a t t h a t l o c a t i o n t h e beam
w i d t h w a s 1.7nnn, which c o n s t i t u t e s t h e l a t e r a l
d i m e n s i o n s of t h e r a n g e c e l l .
The h i g h p a s s f i l t e r of t h e spectrum a n a l y z e r of
t h e Duplex s y s t e m had a c u t o f f f r e q u e n c y of 60Hz.
T h i s a n a l y z e r had a 6OHz u p d a t e r a t e , t a k i n g 128
samples f o r b i d i r e c t i o n a l a n a l y s i s of t h e Doppler
s i g n a l s . The Duplex s y s t e m c o u l d p r o v i d e d i s p l a y s
of t h e i n s t a n t a n e o u s power s p e c t r a , t h a t i s , o f
t h e f r e q u e n c y v e r s u s t h e s q u a r e r o o t of t h e
amplitude.
a t various t i m e instances.
These s p e c t r a v a r y
from one i n t e r v a l t o t h e n e x t , a n d , i n o r d e r t o
convey t h e i n t e r e s t i n g i n f o r m a t i o n , s h o u l d be
smoothed o u t by t i m e a v e r a g i n g .
T h i s h a s been
accomplished i n a s i m p l e manner by m u l t i p l e
e x p o s u r e of many e v e n t s on one f i l m frame. The
a d d i t i v e s u p e r p o s i t i o n t h u s enhanced t h e p o i n t s
on t h e frame which were common t o many s p e c t r a .
S t r i c t l y s p e a k i n g , t h i s is n o t a l i n e a r a v e r a g i n g
p r o c e s s , however, i t e n a b l e d us t o see t h e a v e r a g e
s p e c t r u m , as w e l l as t h e a s s o c i a t e d v a r i a t i o n s .
Examples are shown i n F i g . 3 .
Fig. 3:
F i g . 2:
( a ) t o p , and ( b ) bottom; r e l e v a n t
beam a l i g n m e n t . S e e t e x t .
to
T y p i c a l i n s t a n t a n e o u s s p e c t r a are shown i n F i g . 2
a , b , f o r beam a n g l e s of 9 0 , 6 0 " , r e s p e c t i v e l y ,
r e l a t i v e t o t h e flow d i r e c t i o n .
Note t h e upper
l e f t hand p o r t i o n of t h e s e p i c t u r e s , d i s p l a y i n g
a B-mode image of t h e f l o w t u b e , w i t h t h e d i r e c t i o n of t h e sound beam i n d i c a t e d by a l i n e . These
images were used t o o r i e n t t h e t r a n s d u c e r beam a t
r i g h t a n g l e s t o t h e t u b e w a l l , and t h u s a l s o t o
t h e flow.
D i s p l a y s of s p e c t r u m f r e q u e n c y v e r s u s
t i m e , w i t h t h e a m p l i t u d e r e p r e s e n t e d by a g r e y
s c a l e , are shown a t t h e bottom o f t h e s e two p i c t u r e s . The spectrum a n a l y z e r w a s a l s o used t o
compute t h e t i m e a v e r a g e o v e r s e v e r a l s e c o n d s , o f
t h e peak f r e q u e n c y of c o n t i n u o u s f l o w s p e c t r a ,
d e f i n e d as t h e f r e q u e n c y which i n c l u d e s 95% of
t h e s i g n a l power.
T h i s f r e q u e n c y w a s used t o
e s t i m a t e f l o w v e l o c i t y i n t h e range c e l l , o r
normal o r i e n t a t i o n of t h e beam w i t h r e s p e c t t o
t h e f l o w . The s y s t e m c o u l d a l s o compute and d i s p l a y peak f r e q u e n c i e s of i n s t a n t a n e o u s s p e c t r a .
T h i s mode w a s used t o d i s p l a y p u l s a t i l e f l o w
v e l o c i t i e s in the transverse direction r e l a t i v e
t o t h e beam.
The power s p e c t r a p r e s e n t e d by t h e i n s t r u m e n t are
instantaneous, i.e., derived f o r a short duration
FREQ
FREQ
FREQ
(a)
(b)
(C)
The f l o w model p r e p a r a t i o n c o n s i s t e d of a p l a s t i c
t a n k c o n t a i n i n g t w o t y p e s of t u b e s , one made o f
s e m i - r i g i d p l a s t i c w i t h an i n t e r n a l d i a m e t e r of
7.9mm. a c r o s s - s e c t i o n a l a r e a o f 0.49cm and 1 . 5 m
l o n g . This w a s c o n n e c t e d t o a p l a s t i c r e s e r v o i r
c o n t a i n i n g 3 l i t r e s o f a blood s i m u l a t i n g m i x t u r e
of water and g l y c e r o l , s e e d e d w i t h chromatography
c e l l u l o s e powder.
The o t h e r t u b e w a s of l a t e x
The two
w i t h same i n t e r n a l d i a m e t e r and l e n g t h .
t u b e s were i n s e r t e d i n t o t h e t a n k p a r a l l e l t o
e a c h o t h e r , t o ease t h e r e c o n n e c t i o n of t u b e s when
interchanging tubes.
Flow p a s s e d t h r o u g h e i t h e r
t u b e from an upper t o a lower r e s e r v o i r , w i t h a
pump b e i n g used t o r e t u r n t h e f l u i d t o t h e upper
reservoir, thus maintaining a constant f l u i d l e v e l
For c o n t i n u o u s f l o w , t h e
i n t h e top reservoir.
f l o w r a t e was r e g u l a t e d by c h a n g i n g t h e h e i g h t of
t h e top r e s e r v o i r .
Timed volume measurements
were performed, i n o r d e r t o c a l i b r a t e t h e f l o w
r a t e as a f u n c t i o n of h e i g h t o f t h e t o p r e s e r v o i r .
From t h i s t h e a v e r a g e v e l o c i t y h a s been computed.
F o r p u l s a t i l e f l o w e x p e r i m e n t s , a Harvard I n s t r u ments pump was c o n n e c t e d between t h e t o p r e s e r v o i r
and t h e water t a n k . T h i s pump o p e r a t e d i n a puls a t i l e p a t t e r n , g e n e r a t i n g waveforms s i m i l a r t o
t h o s e o b s e r v e d i n t h e human body.
The a v e r a g e
f l o w r a t e and v e l o c i t y have been d e r i v e d as f o r
t h e c o n t i n u o u s flow.
IV.
Experimental R e s u l t s
E x p e r i m e n t s were performed i n o r d e r t o i n v e s t i g a t e
t h e f e a s i b i l i t y of u s i n g t h e t r a n s v e r s e f l o w t e c h n i q u e f o r measuring c o n t i n u o u s and p u l s a t i l e f l o w s
and t o v e r i f y , as f a r as p o s s i b l e , t h e t h e o r e t i c a l
p r e d i c t i o n s . It h a s been shown above t h a t f o r an
i n f i n i t e s t r i p transducer t h e expected shape f o r
t h e s p e c t r a l d e n s i t y f u n c t i o n i s t r i a n g u l a r , and
- 973
cm/sec vd
150
F i g . 4:
974
V.
Conclusions
VI.
References
Ultrasound
to
Fourier