Name : Dr. R.P.

Tripathi
Date of Birth : 24.12.1956
Designation : Sc F, Deputy Director
Postal Address : Medicinal and Process Chemistry Division
Central Drug Research Institute,
Chattar Manzil Palace
Lucknow-226001 Phone No.(0522) 212411-418 Extn 4462(Office),
(0522) 710421(Residence), 09415521539, 09415004443
Emails: rpt.cdri@gmail.com or rpt.cdri@yahoo.co.in or rp_tripathi@cdri.res.in

Educational Qualifications: M.Sc. (Gorakhpur University), M.Phil, Ph. D.(Delhi University )

Degree University Year Division Field

Ph.D. Delhi University 1985 -- Organic Chemistry
M. Phil Delhi University 1982 A Grade Organic Chemistry
M.Sc. Gorakhpur University 1979 Ist Chemistry
 B.Sc. Gorakhpur University 1977 Ist Biological Sciences

Positions held:
JRF UGC New Delhi 1981-1983
SRF UGC New Delhi 1983-1985
Research Associate NIH project at CDRI, Lucknow 1985-1987
Scientist B, CDRI, Lucknow 1987-1992
Scientist C, CDRI, Lucknow 1992-1997
Scientist E1, CDRI, Lucknow 1997-2001
Scientist EII, CDRI, Lucknow 2001-2006
Scientist F, CDRI, Lucknow 2006 till date

Membership of scientific bodies:

Life member Indian Chemical Society
Life member Indian medicinal chemists association
Life member UP association of advancement of science and technology
Life member Society of biological chemists of India
Member of Association of Carbohydrate Chemists & Technologists of India
Editorial Board Member ARKIVOC
Editorial Board Member Trends in Carbohydrate Research
Editorial Board member of Medicinal Chemistry –An Indian Journal
Associate Editor Carbohydrate News Letter
Reviewer for a number of International Scientific Journals and books
Member of different Selection Committees and Research Boards

Research and training Experience:

About 30 years research experience in different laboratories of Delhi University and Central
Drug Research Institute, Lucknow and abroad.
Countries visited: France, INSA Exchange Programme, University of Rennes 1, Rennes France,
2006, August 2009 Pretoria South Africa, ICS-UNIDO Programme
Projects Handled or in hand: Collaborative project Volkswagen Germany(1), Defense
Research Development Organization New Delhi (2), Indian Council of Medical research (2),
Department of Biotechnology, New Delhi (2)
Research Specialization:
Medicinal Chemistry, Bio-Organic Chemistry, Synthetic Chemistry, Combinatorial Chemistry.
The Group:
Ph.D. Students Supervised:
1. Dr. AR Khan (USA)
2. Rahul Tripathi (Joined BARC Mumbai as senior scientist in
between)
3. Dr. VK Tiwari (Astt. Prof. BHU Faculty)
4. Dr. RC Mishra (Georgia State University USA)
5. Dr. Neetu Tewari ( PG teacher Dehradun)
6. Dr. Diksha Katiyar (Astt. Prof BHU Faculty)
7. Dr. Shyam Sunder Verma (Research Scientist- Lupin Bhopal)
8. Dr. Namrata Dwivedi (Jawahar Lal Nehru PDF, Working at
NCL with Dr. Pradeep Kumar)
9. Dr. Nisha Saxena (Research Scientist GVK Hyderabad)
10. Dr. Biswajit Singh (UNIDO Fellowship (Italy)
11. Miss Jyoti Pandey (SRF, Thesis submitted)
12. Mr. Surendra Singh Bisht (SRF, writing thesis)
13. Miss Nimisha Singh (SRF, writing thesis )
14. Mr. Mridul Mishra (SRF)
15. Mr. Amit Yadav (PG Teacher, selected in between Govt College
Hardoi, Kanpur University)
16. Mr. V.P. Pandey (SRF)
17. Mr. A. Sharma (JRF)
18. Arya Ajay (JRF)
19. Seerat Fatima (JRF)
20. Namrata Anand (JRF)
21. Munna P. Gupt (JRF)
 22. Mr. Rahul Sharma (Res. Asst., DRDO)
23. Dr. Saarvesh Kumar Pandey (Res. Associate CSIR)

Technician:
1. Mr. V.K.Maurya (STA)
Short Term/ Long Term Training:
1. Mr. Vaibhav Garg
2. Mr. P. Yakabaram
3. Miss Aparana Pandey
4. Mr. Ankur Srivastava (presently in Torrent Pharmaceutical)
5. Miss Abha Verma
6. Mr. Beni Ram Sahu
7. Mr. Rajendra Yadav
8. Mr. Pranav Gangwar
9. Miss Pooja Pandey

Honors and Awards:

1. Best paper award by Indian Pharmacological society of India on “3-Cyano-4-methyl-5-
vinyl pyridine: A potent synthetic hepatoprotective agent. P.K.S. Visen, Binduja
Saraswat, G.K. Patnaik, R.C. Srimal, R.P. Tripathi and D.S. Bhakuni. Indian J.
Pharmacol. (1993), 25, 149.”
2. Young Investigator Prize award (2004) (my student Dr. Vinod Tiwari) on our paper:
Solid Phase Combinatorial Synthesis (SFCS) of glycosyl ureas as potential
chemotherapeutic agents, V K Tiwari, N Tewari, R P Tripathi, B K Tripathi, A K
Srivastava, An International Conference in Recent Advances In Biomedical and
Therapeutic Sciences (ICRABTS), 13-15 Jan 2004, at Bundelkhand University, Jhansi-
284128.
3. Dr. D S Bhakuni Award (2004) by Indian Chemical Society, India to my student Dr.
Vinod Tiwari on our paper: Solid phase combinatorial synthesis of C-Nucleosides as a
 potential chemotherapeutic agent, V. K Tiwari, R C Mishra, R P Tripathi, 41st Annual
convention of Chemists, 23-27 Dec 2004 to be held at New Delhi
4. Junior Scientist Best Poster award 2005 by ACCTI: (my student Ankur Srivastva)
on our paper: Synthesis of Glycosyl amino esters as possible inhibitors of DNA-
Topoisomerase4 II Ankur K. Srivastava, Rama P. Tripathi, XX Carbohydrate
Conference, Lucknow university, Lucknow, 24-26rd Nov. 2005
5. Most Cited paper award by Elsevier: Bioorganic & Medicinal Chemistry Most Cited
Paper 2003-2006 award to RP Tripathi on “Synthesis and bioevaluation of glycosyl ureas
as α -glucosidase inhibitors and their effect on Mycobacterium: Neetu Tewari, V.K.
Tiwari, R.C. Mishra, R.P. Tripathi, A.K.Srivastava, R. Ahmad, R. Srivastava and
B.S.Srivastava, Bioorg. Med. Chem., 2003, 11, 2911-2922.”
6. INSA Visiting Scientist Fellowship: Visited University Rennes 1, Rennes, France 1.6.06
to 30.6.06
7. Poster by Surendra Singh Bisht “Synthesis and antitubercular activity of 5-benzyl-3-
phenyl dihydroisoxazole” Second best poster presentation Euro-India First International
Conference on Holistic Medicine 21.8.2008. Surendra S. Bisht, Vivek Parashar Pandey
and R. P.Tripathi.
8. Best poster award: CARBO-XXIII ‘08’ held at Bhavnagar University. Poster entitled
“Synthesis of polyfunctional alkenoyl and alkanoyl C-glycosides and their α-glucosidase
inhibitory activity” presented by Surendra S. Bisht.
9. One of the students of the group Ms Jyoti Pandey selected as participant for Lindau
Meeting 2009 held at Germany in between 28th June-3rd July 2009.

8. List of Publications:

1.

1. An efficient synthesis of pyranosyl homo-C-nucleosides as possible antidiabetic

agents Surendra Singh Bisht, Beni Ram Sahu, Rahul Sharma, A. K. Srivastava, R.P.

Tripathi Tetrahedron, 2010 (Manuscript submitted)

2. Regioselective [3+2] cycloaddition of electron deficient propenones with sugar

azide: an easy access to 1,4,5-trisubstituted-1H-1,2,3-triazoles Nimisha

Singh, S. K. Pandey, Rama P. Tripathi , Carbohydrate Research

(Manuscript Submitted)

3. Synthesis and anticancer activities of biphenyl based chlacones Anindra Sharma,

Munna Prasad Gupt, Bandana Chakravarti, Rituraj Konwar, Rama P. Tripathi,

Bioorganci Medicinal Chemistry 2010, (Manuscript Submitted)

4. Search of antimycobacterial activities in hybrid molecules with benzopyran skeleton

Rama P. Tripathi, Surendra Singh Bisht, Vivek Parashar Pandey, Sarvesh K. Pandey,

Subhra Singh, Sudhir Kumar Sinha and Vinita Chaturvedi, Medicinal Chem. Res.

2010, (Submitted)

5. Synthesis and molecular docking studies of 1-phenyl-4-glycosyl-dihydropyridines as

potent antileishmanial agents Vivek Parashar Pandey, Surendra Singh Bisht, Mridul

Mishra, Ashutosh Kumar, Mohammad Imran Siddiqui, Aditya Verma, Monika

Mittal, Shraddha A. Sane, Suman Gupta and R.P. Tripathi, European Journal Of

Medicinal Chemistry, 2010, ( Artcile in Press)

6. Towards novel antifilarial drugs: challenges and recent developments Prashant Kumar

Singh ‌, Arya Ajay‌, Susheela Kushwaha‌, Rama Pati Tripathi ‌ & Shailja Misra-

Bhattacharya Future Medicinal Chemistry, 2010, 2, 251-283

7. Synthesis and Antitubercular Activity of 5-benzyl-3-phenyl dihydroisoxazoles

Surendra Singh Bishta, Arya Ajay a, Sudhir Kumar Sinhab, Vinita Chaturvedic and

Rama P. Tripathia International Journal of Drug Design and Discovery 2010, 1 ,11-

18
8. Application of Huisgen (3+2) cycloaddition reaction: Synthesis of 1-(2,3-

dihydrobnzofuran-2-yl methyl [1,2,3]-triazoles and their Antitubercular evaluations.

Rama P. Tripathi, A. K. Yadav, S. S. Bisht, V. Chaturvedi, S. K. Sinha European

Journal of Med. Chem. 2010, 45, 142-148.

9. Leishmania donovani: A glycosyl dihydropyridine analogue induces apoptosis like

cell death via targeting pteridine reductase 1 in promastigotes Jaspreet Kaur, Biswajit

K. Singh, Rama P. Tripathi, Prashant Singh, Neeloo Singh Experimental

Parasitology 2009, 123, 258-26

10. Synthesis of plurisubstituted furo[3,2-b]pyrans and furo-[3,2-b] chromenes from D-

glucose Vivek P. Pandey, S.S. Bisht and R.P. Tripathi Trends in Carbohydr. Res. 2009,

1(3), 27-31.

11. BF3.OEt2 catalysed mannosylation of phenolicswith 2,3,4,5-di-O-isopropylidene—D-

mannofurano accompanied by selective in situ deketalization Nisha Saxena, Jyoti

Pandey, A. Tamarkar, A.K. Srivastva and R.P. Tripathi, Trends in Carbohydr. Res.

2009, 1(2), 29-37.

12. An orally effective dihydropyrimidone (DHPM) analogue induces apoptosis-like cell

death in clinical isolates of Leishmania donovani overexpressing pteridine reductase 1

Neeloo Singh, Jaspreet Kaur, Pranav Kumar, Swati Gupta, Nasib Singh, Angana

Ghosal, Avijit Dutta, Ashutosh Kumar, RamaPati Tripathi, Mohammad Imran Siddiqi,

Chitra Mandal and Anuradha Dube Parasitolgy Research 2009, DOI

10.1007/s00436-009-1557-z

13. Synthetic studies in butenonyl C-glycosides: Preparation of polyfunctional alkanonyl

glycosides and their enzyme inhibitory activity. S. S. Bisht, S. Fatima, A. K.

 Tamrakar, N. Rahuja, N. Jaiswal, A. K. Srivastava, Rama P. Tripathi Bioorganic &

Medicinal Chemistry Letters 2009, 19, 2699–2703.

14. An efficient regioselective synthesis of functionalized biphenyls via sequential

reactions of aromatic aldehydes and β-keto esters or ketones. Anindra Sharma, Jyoti

Pandey, R.P. Tripathi Tetrahedron letters 2009, 50, 1812–1816

15. Solution phase synthesis of a library of carbapeptide analogues based on

glycosylamino acid scaffolds, their in silico screening and antimicrobial evaluation.

Jyoti Pandey, Anindra Sharma, Vinod K. Tiwari, Divya Dube, Ravishankar

Ramachandran, Vinita Chaturvedi, Sudhir K. Sinha, Nripendra N. Mishra, Praveen K.

Shukla, Rama P. Tripathi J. Comb. Chem. 2009, 11, 422–427.

16. Synthesis and antitubercular screening of imidazole derivatives. V.K. Tiwari, J.

Pandey, S.S. Verma, V. Chaturvedi, S. Sinha, R.P. Tripathi European Journal of

Med. Chem. 2009, 44, 3350-3355.

17. Organocatalyzed highly atom economic one pot synthesis of tetrahydropyridines as

antimalarials Mridul Misra, Swaroop Kumar Pandey, Vivek Parashar Pandey, Jyoti

Pandey, Renu Tripathi, Rama Pati Tripathi Bioorganic Medicinal Chemistry, 2009,

17, 625-633

18. L-Ascorbic Acid in organic Synthesis- Tripathi, R.P., Biswajit Singh, S.S. Bisht,; J.

Pandey, CURRENT ORGANIC CHEMISTRY 2009, 13, 99-122.

19. 12. Synthesis of 2-sulfanyl-6-methyl-1,4-dihydropyrimidines as a new class of

antifilarial agents B.K. Singh , Mridul Mishra , Nisha Saxena , G.P. Yadav , P.R.

Maulik ,M.K. Sahoo , R.L. Gaur c, P.K. Murthy , R.P. Tripathi, European Journal of

Medicinal Chemistry 2008, 43, 2717-272

20. Pharmacokinetics and excretion of the novel anti-tuberculosis compound 1,2 : 5,6-di-

O- isopropylidene-3-O-(phenyl cyclopropyl methanonyl)-alpha-D-glucofuranose (S-

001-14) after oral doses in rats Lal J, Tripathi R.P., Gupta RC, ARZNEIMITTEL-

FORSCHUNG-DRUG RESEARCH 2008, 58, 410-418.

21. Recent Development on catalytic reductive amination and applications Tripathi R.

P., Verma S. S., Pandey J., V. K. Tiwari CURRENT ORGANIC CHEMISTRY 2008,

12, 1093-1115.

22. Leishmania donovani pteridine reductase 1: Biochemical properties and structure-

modelling studies Kumar P, Kumar A, Verma SS, Dwivedi N., Siddiqui, I., Dube , A;

Tripathi, R.P. ; Singh, N. EXPERIMENTAL PARASITOLOGY 2008, 120, 73-79.

23. Synthesis of azatricyclodiones & octahydro-benzo[f]isoindoles and their antimicrobial

evaluation N Saxena; N Singh; M. Mishra; G. B. Shiva Keshava; P. K. Shukla;

Rama Pati Tripathi. JOURNAL OF ENZYME INHIBITION AND MEDICINAL

CHEMISTRY 2008, 23, 476-482.

24. Synthesis and antitubercular activity of nucleoside analogs based on L-ascorbic acid

and bases Author(s): Tripathi R.P., Dwivedi N, Singh N, Mridul Mishra.

MEDICINAL CHEMISTRY RESEARCH 2008, 17, 53-61.

25. NAD(+)-dependent DNA ligase (Rv3014c) from M-tuberculosis: Strategies for

inhibitor design Dube D, Kukshal V, Srivastava SK, R.P. Tripathi and

R. Ramachandran MEDICINAL CHEMISTRY RESEARCH 2008, 17, 189-198.

26. Aldol reaction of beta-C-glycosylic ketones: synthesis of C-(E)-cinnamoyl glycosylic

compounds as precursors for new biologically active C-glycosides Bisht SS, Pandey J,

Sharma A, Tripathi, R.P. CARBOHYDRATE RESEARCH 2008, 343, 1399-1406.

27. NAD(+)-dependent DNA ligase: A novel target waiting for the right inhibitor.

Dwivedi N, Dube D, Pandey J, Singh BK, Ramchandran R., Tripathi R.P.

MEDICINAL RESEARCH REVIEWS 2008, 28, 545-568.

28. Preparation and reactions of sugar azides with alkynes: synthesis of sugar triazoles as

antitubercular agents Singh BK, Yadav AK, Kumar B, Gaikwad, A.N.; Sinha, S.K.,

Chaturvedi V. and Tripathi R.P. CARBOHYDRATE RESEARCH 2008 , 343, 1153-

1162.

29. Evaluation of Mycobacterium smegmatis as a possible surrogate screen for selecting

molecules active against multi-drug resistant Mycobacterium tuberculosis.

30. Chaturvedi V, Dwivedi N, Tripathi R.P., Sudhir Sinha JOURNAL OF GENERAL

AND APPLIED MICROBIOLOGY 2007, 53, 333-337.

31. D-Glucosamine, a natural aminosugar as organocatalyst for an ecofriendly direct aldol

reaction of ketones with aromatic aldehydes in water. Singh N, Pandey J, Tripathi

R.P. CATALYSIS COMMUNICATIONS 2008, 9 743-746.

32. An efficient chemoselective etherification of phenols in polyfunctional aromatic

compounds Pandey J, Mishra M, Bisht SS, Sharma A. and Tripathi R.P.

TETRAHEDRON LETTERS 2008, 49, 695-698

33. One-pot Amberlite IR-120 catalysed synthesis of glycosyl dihydropyridones. Tiwari

VK, Tewari N, Katiyar D, Tripathi R.P. MONATSHEFTE FUR CHEMIE 2007,

138, 1297-1302

34. An elegant and unprecedented approach to 2-methylbenzofurans. Yadav AK, Singh

BK, Singh N, Tripathi R.P. TETRAHEDRON LETTERS 2007, 48, 6628-6632

35. Synthesis and biological evaluation of potential modulators of malarial Glutathione-S-

transferase(s). R. Ahmad, A. K. Srivastava, R. P. Tripathi, S. Batra and R. D. Walter

J. Journal of Enzyme Inhibition and Medicinal Chemistry, June 2007; 22(3): 327–342

36. L-Ascorbic acid in organic synthesis: a facile synthesis of 4-(butenolide-5-

methylidenyl)-1,4-dihydropyridines. S. S. Bisht, N. Dwivedi, R. P. Tripathi

Tetrahedron Lett., 2007, 48, 1187.

37. Diastereoselective synthesis of glycosylated prolines as alpha-glucosidase inhibitors

and organocatalyst in asymmetric aldol reaction. J. Pandey, N. Dwivedi, N. Singh, A.

K. Srivastava, A. Tamarkar and R. P. Tripathi Bioorganic & Med. Chem. Letters,

2007, 17, 1321.

38. An elegant and unprecedented approach to 2-methyl benzofurans. A. K. Yadav, B. K.

Singh, N. Singh, R. P. Tripathi Tetrahedron Lett, 2007, 48, 6628-6632.

39. L-ascorbic acid in organic synthesis: DBU-catalysed one-pot synthesis of tetramic

acid derivatives from 5,6-O-isopropylidene ascorbic acid. B. K. Singh, S. S. Verma,

N. Dwivedi, R. P. Triapthi Tetrahedron Letters, 2006, 47, 2219.

40. DBU assisted expeditious synthesis of glycosyl dienes via glycosylated beta-hydroxy

esters. S. S. Verma, N. Dwivedi, B. K. Singh, R. P. Tripathi Carbohydr. Res, 2006,

341, 1930.

41. Search of antitubercular activities in tetrahydroacridines: Synthesis and biological

evaluation. R. P. Tripathi, S. S. Verma, J. Pandey, K.C. Agarwal, V. Chaturvedi,

Y.K. Manju, A. K. Srivastva, A. Gaikwad, S. Sinha Biorganic & Med.Chem.Lett.,

2006, 16, 5144.

42. Recent developments in search of antifilarial agents. R. P. Tripathi, D. Katiyar,

N. Dwivedi, B. K. Singh, J. Pandey Curr.Med. Chem., 2006, 13, 3319.

43. Synthesis and antitubercular activity of substituted phenylmethyl- and pyridylmethyl

amines. R. P. Tripathi, N. Saxena, V. K. Tiwari, S. S. Verma, V. Chaturvedi, Y. K.

Manju, A. K. Srivastva, A. Gaikwad and S. Sinha Biorganic & Med. Chem., 2006, 14,

8186.

44. Asymmetric organocatalysis with glycosyl-beta-amino acids: direct asymmetric aldol

reaction of acetone with aldehydes. N. Dwivedi, S. S. Bisht, R. P. Tripathi

Carbohydr. Res., 2006, 341, 2737.

45. An efficient synthesis of tetramic acid derivatives with extended conjugation from L-

Ascorbic acid. B. K. Singh, S. S. Bisht, R. P. Tripathi Beilstein J. Org. Chem., 2006,

Art. No. 24,

46. Fighting Tuberculosis: An old disease with new challenges R. P. Tripathi, N.

Tewari, N. dwivedi, V. K. Tiwari Medicinal Res. Review, 2005, 25, 93.

47. Search of new prototypes for chemotherapy of filariasis: Chemotherapeutic and

biochemical approach. S. Misra-Bhattacharya, P. Bajpai, S. K. Verma, D. Katiyar, N.

Tewari, R. P. Tripathi, I. Bansal, J. K. Saxena. Journal of Parasitology Research,

2005, 95, 383.

48. Synthesis and DNA topoisomerase-II inhibitory activity of unnatural nucleosides. R.

C. Mishra, N. Dwivedi, I. Bansal, J. K. Saxena, R. P. Tripathi Nucleosides,

Nucleotides and Nucleic Acids, 2005, 24, 15.

49. Tetrabutylammonium Hydrogensulphate Catalysed Efficient Synthesis of

Glycosyl(aryl) Dihydropyrimidinones. N. Dwivedi, R. C. Mishra and R. P.Tripathi

Lett. Org. Chem., 2005, 2, 450.

50. Synthesis and Antimycobacterial Activities of Glycosylated Amines and Amino

Alcohols D. Katiyar, V. K. Tiwari, N. Tewari, S. S. Verma, S. Sinha, A. Gaikwad, A.

K. Srivastava, V. Chaturvedi, R. Srivastava, B. S. Srivastava, R.P. Tripathi Eur. J.

Med. Chem., 2005, 40, 351.

51. Mycobacterium tuberculosis NAD+-dependent DNA ligase is selectively inhibited by

glycosylamines compared with human ligase I. S.K. Srivastava, D. Dube, N. Tewari,

N. Dwivedi, R. P. Tripathi, R. Ramchandran Nucleic Acid Research 2005, 33, 7090.

52. NAD+-dependent ligase (Rv3014c) from M.tuberculosis H37Rv: crystal structure of

the adenylation domain and identification of novel inhibitors. S.K Srivastava, R.P

Tripathi, R.Ramachandran J. Biol. Chem., 2005, 280, 30273.

53. Current status of malaria control. R. P. Tripathi, R. C. Mishra, N. Dwivedi, N.

Tewari, S. S. Verma Curr Med Chem., 2005, 12, 2643.

54. An efficient synthesis of aryloxyphenyl cyclopropyl methanones: a new class of anti-

mycobacterial agents. N. Dwivedi, N. Tewari, V. K. Tiwari, V. Chaturvedi, Y. K.

Manju, A. K. Srivastava, A. Gaikwad, S. Sinha, R. P. Tripathi Bioorg Med Chem

Lett., 2005, 15, 4526-30.

55. Synthesis and antitubercular activities of bis-glycosylated diamino alcohols. R. P.

Tripathi, V. K. Tiwari, N. Tewari, D. Katiyar, N. Saxena, S. Sinha, A. Gaikwad, A.

K. Srivastava, V. Chaturvedi, Y. K. Manju, R. Srivastava, B. S. Srivastava. Bioorg

Med Chem., 2005, 13, 5668.

56. Search for new prototypes for the chemotherapy of filariasis: a chemotherapeutic and

biochemical approach. P. Bajpai, S. K. Verma, D. Katiyar, N. Tewari, R. P. Tripathi,

I. Bansal, J. K. Saxena, S. Misra-Bhattacharya Parasitol Res., 2005, 95,383.

57. Reductive amination of glycosyl aldoses: Synthesis of N-glycosylated β -glycosyl

amino alcohols and their antidiabetic potential. S. S. Verma, R. C. Mishra, A. K.

Tamrakar, B. K. Tripathi, A. K. Srivastava, R. P. Tripathi. J. Carbohydr. Chem.,

2004, 23, 493.

58. 4-Methyl-7- (tetradecanoyl)-2H-1-benzopyran-2-one: A novel DNA topoisomerase II

inhibitor with adulticidal and embryo static activity against sub periodic Brugia

malayi. S. Misra-Bhattacharya, D. Katiyar, R. P. Tripathi, J. K. Saxena

Parasitology Research, 2004, 92, 177.

59. A versatile synthesis of Dihydropyrimidinone C-nucleosides. R. C. Mishra, D.

Katiyar, N. Tewari, R. P. Tripathi, Nucleosides, Nucleotides and nucleic Acid, 2004,

23, 531.

60. Diastereoselective Synthesis of Galactopyranosyl Amino Esters and their

Transformations into C-nucleosides, D. Katiyar, R. C. Mishra, R. P. Tripathi,

Journal of Carbohydrate Chemistry, 2004, 23, 49.

61. Search for new antitubercular agents: SPOS of Glycoconjugates on Sieber Amide

resin, R. P. Tripathi, R. C. Mishra, D. Katiyar, K. K. Srivastava, R. Srivastava, B. S.

Srivastava Ind. J. Chem, 2004.

62. Synthesis of Galactopyranosyl Amino Alcohols as a new class of antitubercular and

antifungal agents. N. Tewari, V. K. Tiwari, R. P. Tripathi, A. Gaikwad, S. Sinha, P.

K. Shukla, R. Srivastava and B. S. Srivastava, Bio. Med. Chem.Lett., 2004, 12, 329.
63. An efficient syntheses of α -mannosylated phenolics as α -glycosidase inhibitors. A.

R. Khan, V. K. Tiwari, A. K. Srivastava, R. P. Tripathi J. Enzyme Inhibition 2004,

19, 107.

64. Potential Inhibitors of DNA topoisomerase-II: ruthenium (II) poly-pyridyl and

pyridyl-azine complexes. M. Chandra, A. N. Sahai, D. S. Pandey, R. P. Tripathi, J.

K. Saxena, V.J.M. Reddy, M. Carmen Peutra, Pedro Valerga J. Organometallic

Chemistry 2004, 689, 2256.

65. 1,3 Dipolar Cycloaddition of Glycosyl Nitrile Oxides with Alkenes:

Diastereoselective Synthesis of Glycosyl Isoxazolines. R.C. Mishra, N. Tewari, S. S.

Verma and R. P. Tripathi , J. Carbohydr. Chem. 2004, 23, 353.

66. Phenylene bridged bis -glycosyl ureides as potential antileishmanial agents. N.

Tewari, Ramesh, R. C. Mishra, S. Gupta, R. P. Tripathi, Bioorg. Med. Chem.Lett.

2004, 14, 4055.

67. Tetrabutylammonium Hydrogen Sulphate Catalysed Eco-friendly and Efficient

Synthesis of Glycosyl 1,4-Dihydropyridines. N. Tewari, N. Dwivedi, R. P. Tripathi

Tetrahedron Lett., 2004 , 45, 9011.

68. Solid phase synthesis of cyclopropyl phenyl methanones, R. K. Grover, R. C. Mishra,

B. Kundu, R. P.Tripathi R. Roy. Tetrahedron Lett. 2004, 45, 7331.

69. Glutathione synthesis in filarial worms: an attractive target for the design and

synthesis of new antifilarials. K. Arora, R. C. Mishra, R. P. Tripathi, A.

K.Srivastava, Rolf D. Walter. Med. Chem Res., 2004, 13, 687.

70. 7-O-(4-methyl piperazin-acetyl)-4-methyl-2H-1-benzopyran-2-ones: A novel lead

compound for antifilarial activity. R. P. Tripathi, V. K. Tiwari, S. Bhattacharya, K.

Srivastava, V. M. L. Srivastava and K. Murty Acta Tropica, 2003, 87, 215.

71. DBU Assisted Cyclorelease Elimination: Combinatorial Synthesis and γ -glutamyl

cystein synthetase & glutathione-S- transeferase Modulatory Activity of C-

nucleoside anlogs. R. C. Mishra, N. Tewari, K. Arora, R. Ahmad, R. P. Tripathi, V.

K. Tiwari, R. D. Walter , A. K. Srivastava Combi Chem & Highthroughtput

Screening, 2003, 6, 37.

72. Synthesis and Antifilarial Evaluation of N1, Nn- Diglycosylated Diaminoalkanes. V. K.

Tiwari, N. Tewari, D. Katiyar, R. P. Tripathi, K. Arora, S. Gupta, A. K Srivastava,

M. A. Khan, P. K. Murthy Bio-Org. & Med. Chem., 2003, 11, 1789.

73. Synthesis and antifilarial evaluation of 7-O-acetamidyl-4-alkyl-2H-1-benzopyran-2-

ones. D. katiyar, V. K.Tiwari, R. P.Tripathi, V. J. M. Reddy, S. Bhattacharya, J.

K.Saxena Arzn. Forsch/Drug Research, 2003, 53, 857.

74. Synthesis and bioevaluation of glycosyl ureas as α -glucosidase inhibitors and

their effect on Mycobacterium. N. Tewari, V. K. Tiwari, R. C. Mishra, R. P.

Tripathi, A. K.Srivastava, R. Ahmad, R. Srivastava, B. S. Srivastava Bioorg. Med.

Chem., 2003, 11, 2911.

75. Amberlite IR -120 Catalysed Efficient Synthesis of Glycosyl Enaminones and their

Application. N. Tewari, D. Katiyar, V. K. Tiwari and R. P. Tripathi Tetrahedron

Lett., 2003, 44, 6639.

76. Synthesis and Antimycobacterial Activity of 3,5-Disubstituted Thiadiazine thiones. D.

Katiyar, V. K. Tiwari, R. P. Tripathi, A. K. Srivastava, V. Chaturvedi, R. Srivastava

and B. S. Srivastava Bio. Med. Chem., 2003, 11, 4369.

77. Synthesis of Glycosylated β-Amino Hydroxamates as New Class of Antimalarials. R.

C.Mishra, R. Tripathi, D. Katiyar, N. Tewari, D. Singh, and R. P.Tripathi Bio. Med.

Chem., 2003, 11, 5363.

78. Combinatorial and conventional synthesis of glycohybrid molecules as new class of

antitubercular agents V. K. Tiwari, R. P Tripathi, V. Chaturvedi, A. Srivastava, S.

Sinha, R. Srivastava, B. S. Srivastava Medicinal Chem Res., 2003, 12, 394.

79. Synthesis of Glycosylated β -amino acids as new class of antitubercular agents. R. P.

Tripathi, R. Tripathi, V. K. Tiwari, Laxmi Bala, S. Sinha, A. Srivastava, R.

Srivastava, B. S. Srivastava Eur. J. Med. Chem., 2002, 37, 773.

80. Unexpected Isomerisation of Double bond with DBU: A Convenient Synthesis of

Tetrasubstituted α -alkylidene tetrahydrofuranoses. V. K. Tiwari, R. P. Tripathi

Indian J. Chem, 2002, 41B, 1681.

81. Conjugate Addition of Amines to Sugar Derived Olefinic Ester: Synthesis of

Glycosylated Amino Esters as DNA Topoisomerase –II Inhibitors. A. R. Khan, R. P.

Tripathi, V. K.Tiwari, R. C. Mishra, V. J. M. Reddy and J. K. Saxena, J.

Carbohydrate Chemistry, 2002, 21, 591.

82. DBU/ TBAB/4A0 Catalysed cyclatic amidation reactions: A highly efficient &

convenient synthesis of C-Nucleosides. N. Tewari, R. C. Mishra, V. K. Tiwari, R. P.

Tripathi, Synlett, 2002, 11, 1779.

83. Synthesis and immunomodulatory activities of 2'-hydroxy-3'-N, N-Disubstituted

aminopropyl-α-D-glucofuranoses as immunomodulators. A. R. Khan, R. P. Tripathi,

A. P. Bhaduri, R. Sahai, A. Puri, L. M. Tripathi, V. M .L Srivastava, Eur. J. Med.

Chem, 2001, 36, 103.

84. Identification of inhibitors of DNA Topoisomerase-II from a synthetic library of

glycoconjugates. R. P. Tripathi, S. K. Rastogi, B. Kundu, J. .K. Saxena, V. J. M.

Reddy, S. Srivastava, S. Chandra, and A.P. Bhaduri Combi. Chem. &

Highthroughput Screen., 2001, 4, 237.

85. Study on the loading and reactions of naked sugars on solid phase. R. C. Mishra, R. P.

Tripathi Medicinal Chemistry Research, 2001, 10, 548.

86. Glycosyl amino acid derivatives as inhibitors of yeast DNA topoisomerase. I. P. Jain,

Z. K. Khan, R. P.Tripathi, B. L. Tekwani Abstract of the symposium CTTDDR

published in Medicinal Chemistry Research, 2001, 10, 550.

87. Synthesis and antiviral activity of 3-O-(2'-hydroxy aminopropyl)- α -D-

glucofuranoses. N. S. Rana, P. Gupta, R. P. Tripathi, A. P. Bhaduri Acta

Pharmaceutica, 2001, 1, 63.

88. Antifilarial activity of 2H-1-Benzopyran-2-ones (coumarins). R. P. Tripathi, R.

Tripathi, S. N. Singh, A. P. Bhaduri, R. K. Chaterjee and K. Murthy Acta Tropica,

2000, 76, 101.

89. α -Cyano ethyl propenoates: a new class of antileishmanial agents. S. Tewari, R. P.

Tripathi, A. R. Khan, S. Gupta, J. C. Katiyar, A. P. Bhaduri Arzen Forsch/ Drug

Res., 1999, 49, 144.

90. DNA Topoisomerases of filarial parasites:Effect of antifilarial compounds. U. Pandya,

J. K. Saxena, S. M. Kaul, P. K. Murthy, R. K. Chatterjee, R .P. Tripathi, A. P.

Bhaduri, O. P. Shukla Medical Science Res., 1999, 27, 103.

91. Hepatoprotection by 3-cyano-5-ethenyl-4-methyl pyidine (compound 89/62) against

experimentally induced liver injury in rats. S. Srivastava, S. C. Tripathi, A. K.

Srivastava, D. S. Bhakuni, R. P. Tripathi and G. K. Patnaik Acta Pharmaceutica,

1997, 47, 117.

92. Cabohydrates in biological recognition. A. R. Khan, R. P. Tripathi, A. P. Bhaduri,

Biol. Memoirs., 1997, 23, 73.

93. Synthesis of 2,3-anhydronucleosides of pyrazolo(3,4-d) pyrimidine as antiviral agents.

R. P.Tripathi, Anil Mishra, Ram Pratap, D. S. Bhakuni Indian J. Chem., 1996, 35B,

441.

94. Asymmetric induction in the epoxidation of 3-and 5-O-allyl glycofuranoses with

mCPBA. A.R. Khan. R. P. Tripathi, A. P. Bhaduri Indian J. Chem. 1996, 35B, 405.

95. Synthesis and spermicidal activities of dithiocarbamates. R. P. Tripathi, A. R. Khan,

B. S. Shetty and A. P. Bhaduri Acta Pharmaceutica, 1996, 46, 169.

96. Effect of 3-O- (aminoalkyl)- α -D-gluco (xylo) furanoses on glutathione metabolism

of falarial parasites. A. K. Srivastava, R. P. Tripathi, A. R. Khan, A. P. Bhaduri, S.

N. Singh, R. K. Chatterjee Helminthologia, 1995, 32, 25.

97. Synthesis and antiviral activities of 3-O-(aminoalkyl)-1,2-O-isopropylidene-α-D-

gluco-(xylo)furanoses, R. P.Tripathi, V. Singh, A. R. Khan , A. P. Bhaduri, G.

Saxena, K. Chandra Indian J Chem., 1995, 34B, 791.

98. Effect of glucofuranose ring in the asymmetric induction to the appended side chains.

R. P. Tripathi, A. R.Khan, A. P. Bhaduri, S. Bhatnagar, A. K. Srivastava, “Trends in

carbohydrate chemistry,” edited by P. L.Soni, Surya International Publication,

Dehradun pp 1-4 (1995).

99. Glutathione-S-transferase activity in S. cervi females and effect of new antifailarial

compounds. A. K. Srivastava, R. P. Tripathi, A. R. Khan, A. P. Bhaduri, S. N.Singh,

R. K. Chatterjee Indian J. Parasitology, 1994, 46, 169

100. 3-Cyano-4-methyl-5-vinyl pyridine: A potent synthetic hepatoprotective agent.

P.K.S. Visen, Binduja Saraswat, G. K. Patnaik, R. C. Srimal, R. P. Tripathi, D. S.

Bhakuni. Indian J. Pharmacol., 1993, 25, 149.

101. 3-Cyano-4-methyl-5-vinyl pyridine: A potent synthetic hepatoprotective agent.

P.K.S. Visen, Binduja Saraswat, G. K. Patnaik, R. C. Srimal, R. P. Tripathi, D. S.

Bhakuni. Indian J. Pharmacol., 1993, 25, 149.

102. Synthesis of 1/2-benzyl-4,6-disubstituted –1H/2H-pyrazolo(3,4-d)-pyrimidines

and their antileishmanial activities. A. Mishra, L. M. Ojha, R. P. Tripathi, R. Pratap,

D. S. Bhakuni. Indian J. Heterocyclic Chem., 1991, 1, 51.

103. Studies in nucleosides: PartXX: Synthesis and antileishmanial activities of 4-oxo-

(5H)- pyrazolo{3,4-d] pyrimidine-α & β -nucleosides. A. Hasan, R. P. Tripathi,

Ram Pratap, D. S. Bhakuni Indian J. Chem., 1989, 28B, 403.

104. Studies in nucleosides: PartXIX: Synthesdis of 4,6-disubstituted derivatives of 1-

α -D-arabinofuranosylpyrazolo{3,4-d] pyrimidines and their antiviral activities. R. P.

Tripathi, Ram Pratap, D. S. Bhakuni Indian J. Chem., 1987, 26B, 1054.

 105. Studies in nucleosides: PartXVII: Synthesis of 4-amino-6-methoxy pyrazolo{3,4-

d] pyrimidine and 4-amino-6-methylthio pyrazolo[3,4-d]pyrimidine ribosides and

their antiviral activities. R. P. Tripathi, A. Hasan, Ram Pratap, D. S. Bhakuni Indian

J. Chem., 1987, 26B, 851.

106. A novel synthesis of 4-propyl –2H-1-benzopyran-2-ones. V. K. Ahluwalia, R. P.

Singh, R. P. Tripathi Montash fur chemie, 1984, 115, 765.

107. An efficient synthesis of 4-propylpyranocoumarins. V. K. Ahluwalia, R. P. Singh,

R. P. Tripathi Gazzeta Chimica. Italiana, 1984, 114, 505.

108. An elegant synthesis of 6-butyryl chromans and chromenes. V. K. Ahluwalia, R.

P. Singh, R. P. Tripathi Gazzeta Chimica. Italiana,1984, 114, 359.

109. A facile synthesis of 4-propyl psoralen and angellicine derivatives. V.K.

Ahluwalia, R. P. Tripathi J. Indian Chem Soc., 1984, LXI, 1023.

110. A convenient synthesis of propyl substituted benzofuro coumarins. V. K.

Ahluwalia, R. P. Singh, R. P. Tripathi Heterocycles, 1984, 22, 2783.

List of Patents filed or in process:

1. A process for the synthesis of α & β - isomers of 6-amino-4-oxo-(5H)- pyrazolo{3,4-d]

pyrimidine-α & β -nucleosides. Patent in India No. 173563
2. A novel combinatorial library of 3-substituted amino-3-glycosylated propanoates useful
as antifungal and antibacterial agents. Rama Pati Tripathi, Praveen Kumar Shukla,
Sudhir Sinha, Ranjana Srivastava, Kishor Kumar Srivastava, Vinita Chaturvedi, Anil
Srivastava, Brahm Shankar Srivastava. 0716DEL2004 Filing date 4/15/04
3. A process for the preparation of novel combinatorial library of 3-substituted amino-3-
glycosylated propanoates useful as antifungal and antibacterial agents. Rama Pati
Tripathi, Bijoy Kundu, Praveen Kumar Shukla, Sudhir Sinha, Ranjana Srivastava,
 Kishor Kumar Srivastava, Vinita Chaturvedi, Anil Srivastava, Brahm Shankar Srivastava.
(NF / 315 / 01)

4. A process for the preparation of novel combinatorial library of 3-substituted amino-3-

glycosylated propanamides useful as antifungal and antibacterial agents. Rama Pati
Tripathi, Bijoy Kundu, Praveen Kumar Shukla, Sudhir Sinha, Ranjana Srivastava,
Kishor Kumar Srivastava, Vinita Chaturvedi, Anil Srivastava, Brahm Shankar Srivastava.
Patent Appl. No.: 1272DEL2001 Filing Date: 24/12/2001 Patent No.: 194984 Grant
Date: 17/03/2006
5. A novel combinatorial library of 3-substituted amino-3-glycosylated propanamides useful
as antifungal and antibacterial agents. Rama Pati Tripathi, Praveen Kumar Shukla,
Sudhir Sinha, Ranjana Srivastava, Kishor Kumar Srivastava, Vinita Chaturvedi, Anil
Srivastava, Brahm Shankar Srivastava. 1529DEL2004 Filing Date 8/17/04 Patent No.:
196956 Grant Date: 23/06/2006
6. A process for the preparation of novel N1, Nn-diglycosylated diamino alkanes useful as
inhibitors of parasitic enzymes. Rama Pati Tripathi, Vinod Kumar Tiwari, Arvind
Kumar Srivastava, Kavita Arora, Sapana Gupta, K.P. Murthy, R. D. Walter.
(INF/PAT/05/2001)
7. A process for the preparation of novel 4-alkyl-7-O-(acetamid-2-yl)-2H-1-benzopyran-2-
ones useful as inhibitors of helminthic and protozoan DNA topoisomerases. Rama Pati
Tripathi, Jitendra Kumar Saxena, Onkar Prasad Shukla, Subhash Chandra, Puvada
Kalpana Murthy, Shailija Bhattacharya, Kamal Kamboj, Anil Kumar Dwivedi, Ranjeet
Kumar Chatterjee, Satyawan Singh, Vishwa Mohan Lal Srivastava, Anil Kumar Rastogi,
Amiya Prasad Bhaduri. 620/DEL/01
8. N1, Nn-diglycosylated diamino alkanes useful as inhibitors of parasitic enzymes) Rama
Pati Tripathi, Vinod Kumar Tiwari, Arvind Kumar Srivastava, Kavita Arora, Sapana
Gupta, P. K. Murthy, R. D. Walter. (INF/PAT/06/2001)
9. A process for the preparation of novel combinatorial library of N1 – glycosylated and N3 -
substituted ureas and thioureas useful as antitubercular agents, Rama Pati Tripathi, Vinod
Kumar Tiwari, Ram Chandra Mishra, Ranjana Srivastava, Sudhir Sriwastava, Vinita
 Chaturvedi, Kishor Kumar Srivastava, Brahm Shankar Srivastava 264 DEL2002 Filing
Date/ 20.03.2002
10. Novel combinatorial library of N1 – glycosylated and N3 –substituted ureas Useful as
antitubercular agents, Rama Pati Tripathi, Vinod Kumar Tiwari, Ram Chandra Mishra,
Ranjana Srivastava, Sudhir Sriwastava, Vinita Chaturvedi, Kishor Kumar Srivastava,
Brahm Shankar Srivastava. 0715DEL2004 4/15/04 Patent Number(s): IN200400715-I1
11. Diglycosylated diaminoalcohol as novel antitubercular agents, Rama Pati Tripathi,
Vinod Kumar Tiwari, Neetu tewari, Ranjana Srivastava, Sudhir Srivastava, Vinita
Chaturvedi, Kishor Kumar Srivastava, Brahm Shankar Srivastava. 999/DEL/30.09.2002.
12. A process for the preparation of diglycosylated diaminoalcohol as antitubercular agents
Rama Pati Tripathi, Vinod Kumar Tiwari, Neetu tewari, Ranjana Srivastava, Sudhir
Srivastava, Vinita Chaturvedi, Kishor Kumar Srivastava, Brahm Shankar Srivastava
(998/DEL/30.09.2002)
13. Novel Galactopyranosylated aminoalcohols useful in chemotherapy of tubercular
infections; Rama Pati Tripathi, Neetu Tewari, Ram Chandra Mishra, Ranjana
Srivastava, Sudhir Sinha, Anil Srivastava, Vinita Chaturvedi, Kishor Kumar Srivastava,
Brahm Shankar Srivastava 1212DEL2004 Filing Date 6/30.2004
14. A process for the preparation of Galactopyranosylated aminoalcohols useful in
chemotherapy of tubercular infections, Rama Pati Tripathi, Neetu tewari, Ram Chandra
Mishra, Ranjana Srivastava, Sudhir Sinha, Anil Srivastava, Vinita Chaturvedi, Kishor
Kumar Srivastava, Brahm Shankar Srivastava 1609DEL2004 Filing Date 8/26/04
15. Novel 1,3,5-thiazidine -2-thiones useful in chemotherapy of tubercular infections, Rama
Pati Tripathi, Diksha Katiyar, Ranjana Srivastava, Anil Srivastava, Vinita Chaturvedi,
Kishor Kumar Srivastava, Brahm Shankar Srivastava 1098DEL2004 Filing Date
6/11/2004

16. A process for the preparation of 1,3,5-thiazidine -2-thiones useful in chemotherapy of

tubercular infections, Rama Pati Tripathi, Diksha Katiyar, Ranjana Srivastava, Anil
Srivastava, Vinita Chaturvedi, Kishor Kumar Srivastava, Brahm Shankar Srivastava,
1098DEL2004 Filing Date 6/11/04
 17. Novel Phenyl Cyclopropyl methanones useful as antitubercular agents, Rajesh Grover,
R.C. Mishra, S.S. Verma, R.P. Tripathi, Raja Roy, A.K. Dwivedi, S.Singh, Ranjana
Srivastava, Anil Srivastava, Vinita Chaturvedi, Manju Y. Krishnan , Brahm Shankar
Srivastava 0636DEL2004 Filing Date 3/31/2004
18. A process for the preparation of novel glycosylated aminoalcohols useful in the treatment of
tuberculosis Ramapati Tripathi, Vinod Kumar Tiwari, Neetu Tewari, Diksha Katiyar, Anil Kumar
Dwivedi, Styawan Singh, Anil Gaikwad, Sudhir Sinha, Ranjana Srivastava, Sudhir Srivastava, Vinita
Chaturvedi, Kishor Kumar Srivastava, Brahm Shankar Srivastava 1217DEL/04 30.6.04
19. Novel Dispiro cyclalkanones useful as inhibitors of NAD+-dependent DNA Ligase and
antitubercular agents Rama Pati Tripathi, Jyoti Pandey, Nimisha Singh, Divya Dube, Vandna Kukshal,
Shalini Bhatnagar, Sudhir Sinha, Vinita Chaturvedi, Ravishankar Ramchandran 0080NF2009
20. An Antitubercular formulation of 4-alkoxy pheny cyclopropyl alkanols, Rama Pati Tripathi,
Prabhat Ranjan Mishra, Girish Kumar Gupta, Surendra Singh Bisht, Jyoti Pandey, Vinita Chaturvedi,
Sudhir , Vinita Chaturvedi, Versa Gupta, Anil Kumar Dwivedi 0082NF2009

Chapters in Book:

1. Synthesis and antifilarial evaluation of a few carbohydrate derivatives. R.P.Tripathi,

V.Singh, A.R.Khan, A.P.Bhaduri, S.Bhatnagar and A.K. Srivastava. “Trends in
Carbohydrate Chemistry,” edited by P.L.Soni, Surya International Publication,
Dehradune pp 1-4 (1995).

2. Search of new drugs for tuberculosis: Glycosylated β -amino acids as new class of
antitubercular agents, Trends in Carbohydrate Chemistry, Vol-8 (in press), and
Published by Surya international publication, Dehradun. Authors: V.K.Tiwari, R. P.
Tripathi, R. Tripathi, Laxmi Bala, S. Sinha, A. Srivastava, R. Srivastava, B.S.
Srivastava.

Paper Presented in conference: (Last three years)

1. Identification of inhibitors of DNA Topoisomerase II from a synthetic library of
glycopeptides, R. P. Tripathi, S. K. Rastogi, B. Kundu, J.K. Saxena, S.
Srivastava, V.J.M. Reddy, S. Chandra, A. P. Bhaduri, Fifth IUPAC International
Symposium on Bio-Organic Chemistry, ISBOC-5, at National Chemical
Laboratory- Pune, 3rd Jan - 4 th Feb 2001.

2. Unexpected Isomerisation reaction with DBU: An easy access to α -alkylidene

tetrahydrofuranose, V. K. Tiwari, R. P. Tripathi, Current Trends in Drug
Discovery Research, 11-15 Feb 2001 at CDRI Lucknow.

3. Antifilarial profile of a novel lead compound: 7-O- (4-methyl piperazin-acetyl)-4-

methyl 2H-1- benzopyran-2-ones, R. P. Tripathi, V. K. Tiwari, S. Bhattacharya,
K. Srivastava, V. M. L. Srivastava and K. Murty, Indian Conference of
Parasitology, 1-3 Oct 2001 at Jodhpur.

4. Synthesis of glycosylated amino esters as DNA topoisomerase-II inhibitors

A.R.Khan, R. P. Tripathi, V. K. Tiwari, R. C. Mishra, V. J. M.Reddy and J. K.
Saxena, National Biorganic Symposium 7, GNDU Amritsar 7-9 Nov 2001

5. Depletion of intracellular Glutathione of Setaria cervi by Dimethylmaleate,

Phorone and Aminoalkane derivatives. S. Gupta,V. K. Tiwari, R. P. Tripathi, A.
K. Sriwastava, Indian Conference of Parasitology, 1-3 Oct 2001 at Jodhpur.

6. Glycosylated β -amino acids as new class of antitubercular agents. V. K. Tiwari,

R. P. Tripathi, R. Tripathi, Laxmi Bala, S. Sinha, A. Srivastava, R. Srivastava, B.
S. Srivastava, 16th Carbohydrate Conference,6-7 December at Trivendrum.

7. Conjugate Addition of Hydrazine and Hydroxyl Amines to Sugar derived Olefinic

Esters: Synthesis of glycosylated heterocycles. R. C. Mishra, N. Tewari, R. P.
Tripathi, 22-24 Feb Alembic Ltd Vadodara.
8. Synthesis and bioevaluation of glycosyl ureas as α -glucosidase inhibitors and
antituberculosis agents. V. K. Tiwari, N. Tewari, R. C. Mishra, R. P. Tripathi, A .K.
Srivastava, R. Ahmad, R. Srivastava and B. S. Srivastava. International symposium on
Drug Discovery and Process Research, Shivaji University Kolhapur, January 23-
25, 2003.

9. A versatile synthesis of dihydropyrimidinone C-Nucleosides. R. C. Mishra, D.

Katiyar, N. Tewari, R. P. Tripathi, International symposium on Drug Discovery
and Process Research, Shivaji University Kolhapur, January 23-25, 2003.

10. α -glucosidase inhibitory potential of glycosyl ureas. N. Tewari, R. C. Mishra, R.

Ahmad, A. K. Srivastava, and R. P. Tripathi, International conference on Role of
Free Radical and antioxidants in Health and disease, King George Medical
University Lucknow, February 10-12, 2003.

11. Glutathione modulatory potential of 4-alkyl-7-O-acetamidyl coumarins in

malarial and filarial parasites, D. Katiyar, K. Arora, R. Ahmad, A. K. Srivastava,
and R. P. Tripathi, International conference on Role of Free Radical and
antioxidants in Health and disease, King George Medical University Lucknow,
February 10-12, 2003.

12. Synthesis and antitubercular activity of Novel purines Derivatives of 2,3-O,O-Dialkyl-6-

deoxy-L-ascorbic acid and 4,5 didehydro-5,6-dideoxy-L-ascorbic acid. N. Dwivedi, R. P.
Tripathi. XXI Carbohydrate Conference, Deptt of Chem Delhi University, 26-29 Nov.
2006.
13. Diastereoselective synthesis of glycosylated prolines as α-glucosidase inhibitors and
organocatalyst in asymmetric aldol reactions. Jyoti Pandey, Namrata Dwivedi, Nimisha
Singh, A. K. Srivastava, A. Tamarkarb and R. P. Tripathi XXI Carbohydrate Conference,
Deptt of Chem Delhi university, 26-29 Nov. 2006
 14. Synthesis and Antitubercular Activity of Nucleoside analogs based on purines and L-
Ascorbic acid. N. Singh, N. Dwivedi, M. Misra and R. P. Tripathi. Current trends in drug
discovery 17-21 Feb 2007, C.D.R.I Lucknow.
15. L-Ascorbic acid in organic synthesis:An Ecofriendly and facile synthesis of 4-vinyl-1, 4-
Dihydroryridine Surendra. S. Bisht Current trends in drug discovery 17-21 Feb 2007,
C.D.R.I Lucknow.
16. An efficient synthesis of tetramic acid derivatives with extended conjugation from L-
th
Ascorbic Acid Biswajit K Singh, 11 ISCB conference (ISCBC 2007) International
Conference on Advances in Drug Discovery research Feb 24-26 2007. Dr. Babasaheb
Ambedkar Marathwada University.
17. Synthesis and antitubercular activity of substituted phenylmethyl- and pyridylmethyl
th
amines Nisha Saxena, R P, Triapthi 11 ISCB conference (ISCBC 2007) International
Conference on Advances in Drug Discovery research Feb 24-26 2007. Dr. Babasaheb
Ambedkar Marathwada University.
18. The gateway to solution phase synthesis of a library of an artificial glycopeptides:
in silico screening and antimicrobial evaluation Jyoti Pandey, A. Sharma, R.
Ramachandran, V. Chaturvedi, S. Sinha, P. K. Shukla and Rama P. Tripathi*
International Conference on Biomedical and Bioorganic Chemistry Mar 04, 2009 at Delhi
University and Jan 22-24, 2009 at Bhavnagar University, Bhavnagar (Gujarat) India.
19. Synthesis of polyfunctional alkenoyl and alkanoyl C-glycosides and their α-
glucosidase inhibitory activity.” Surendra Singh Bisht, Anindra Sharma, Arvind
K. Srivastva and Rama P. Tripathi. Presented in CARBO-XXIII conference Jan
22-24, 2009 at Bhavnagar University, Bhavnagar (Gujarat) India.
Besides above more than 20 papers have also been presented in different national and
international seminars and conferences.

Invited Lectures:

1. Polysaccharides structure & function- its relevance to medicinal chemists-In TAB

Meeting CSIR Science centre New Delhi 9th July 1991.
2. Carbohydrtes in Drug Design- In modern Trends in chemical research: From laboratory to
Industry, March 5-7 1992, APS University Reewa, M.P.

3. Strategies in the design of antiviral agents: National Seminar organized by Purvanchal

academy of Sciences March 1993, at Neoria Jaunpur.

4. Chemotherapy of filariasis-National Seminar organized by Purvanchal Academy of

Sciences March 1993, at Purvanchal University Jaunpur 1994.

5. Development of drugs against Tuberculosis- Annual Convention Of Chemical Society of

DBS college, Kanpur University, Kanpur December 2002

6. Carbohydrates in Drug Design: National Conference on Chemistry at Interfaces-Trends

and Perspectives, December 19-20, 2003, Sant Longowal Institute of Technology,
Longowal, Punjab.

7. Application of carbohydrates in development of ne chemotherapeutics APS University

March 2004 New trends in Chemistry

8. Carbohydrates in Drug design: An attempt to develop new generation of

Antimycobacterial Agents XIX Carbohydrate Conference, Forest Research Institute
Dehradun. Uttaranchal 1-3rd December 2004.

9. Search of New Antimycobacterial Agents. Bundelkhand University Jhansi, Jan 2005.

10. Carbohydrates in Drug Desin against Tuberculosis. XIX Carbohydrate Conference,

Chemistry Department Lucknow University, Lucknow 23-26 Nov 2005 December 2005.
11. Role of sugars in the development of new generation of Antitubercular agents. Chemistry
Deptt. BHU Varanasi 24 March 2006.

10. Tuberculosis: New Drug Development University of Rennes1 FRANCE 13th June 2006.
11. Potential of Simple Sugars in Chemistry and Medicinal Chemistry. BHU, 30th Sept 2006.

12. Explorations in Medicinal Chemistry with Simple Sugars. Delhi University, 27th Nov 2006.

13. BHU Varanasi, 2007

14. Application of Monosaccharides as Chemotherapeutics NIPER Chandigarh India December 2007

15. Our effort to develop new antitubercular agents 1st International Euro-India Conference
on Holistic Medicine 21. 8. 2008 Kottayam, Kerala.

16. Bhavnagar University, Bhavnagar (Gujarat) 2009.

17.Allahabad University, Allahabad 09.02.2009.

18. BHU Varanasi, 2009

19. Delhi University, Delhi 04.03.2009.

20. Design and Development of new generation of Antitubercular agents Pretoria South
Africa August 3, 2009 in ICS-UNIDO programme