BC 2800vet
BC 2800vet
BC 2800vet
Service Manual
Copyright
2006 Shenzhen Mindray Bio-medical Electronics Co., Ltd. All rights Reserved.
Release, amendment, reproduction, distribution, rent, adaption and translation of this manual
in any manner whatsoever without the written permission of Mindray is strictly forbidden.
All information contained in this manual is believed to be correct. Mindray shall not be liable
for errors contained herein nor for incidental or consequential damages in connection with the
furnishing, performance, or use of this manual.
Mindray is responsible for safety, reliability and performance of this product only in the
condition that:
all installation operations, expansions, changes, modifications and repairs of this product
are conducted by Mindray authorized personnel;
the electrical installation of the relevant room complies with the applicable national and
local requirements;
I
z This equipment must be operated by skilled/trained medical professionals.
z Be sure to operate the analyzer under the situation specified in this manual;
otherwise, the analyzer will not work normally and the analysis results will
be unreliable, which would damage the analyzer components and cause
personal injury.
II
Warranty
Exemptions
Mindray's obligation or liability under this warranty does not include any transportation or
other charges or liability for direct, indirect or consequential damages or delay resulting from
the improper use or application of the product or the use of parts or accessories not approved
by Mindray or repairs by people other than Mindray authorized personnel.
any Mindray product which has been subjected to misuse, negligence or accident;
any Mindray product from which Mindray's original serial number tag or product
identification markings have been altered or removed;
Return Policy
Return Procedure
In the event that it becomes necessary to return this product or part of this product to Mindray,
the following procedure should be followed:
1. Obtain return authorization: Contact the Mindray Service Department and obtain a
Customer Service Authorization (Mindray) number. The Mindray number must appear on
the outside of the shipping container. Returned shipments will not be accepted if the
Mindray number is not clearly visible. Please provide the model number, serial number, and
a brief description of the reason for return;
2. Freight policy: The customer is responsible for freight charges when this product is
shipped to Mindray for service (this includes customs charges);
3. Return address: Please send the part(s) or equipment to the address offered by
Customer Service department.
III
Company Contact
Manufacturer: Shenzhen Mindray Bio-Medical Electronics Co., Ltd.
Address: Mindray Building, Keji 12th Road South, Hi-tech Industrial Park,
Nanshan,ShenZhen 518057, P.R.China,
Phone: +86 755 26582479 26582888
Phone: 0049-40-2513175
Fax: 0049-40-255726
IV
Table of Contents
Copyright I
Warranty.............................................................................................................. III
Return Policy....................................................................................................... III
1
Table of Contents
5 Maintenance............................................................................................. 5-1
5.1 General Guidelines ................................................................................ 5-2
2
Table of Contents
8 Appendices ..............................................................................................A-1
A Error Code..............................................................................................A-1
3
1 Hardware
The CPU, FPGA and Super I/O are the major components on the board. The CPU carries out
the instructions and functions as the core of the board. The FPGA functions as the relay
between the CPU and the Super IO. The Super I/O includes various interfaces that can be
accessed by the CPU through the FPGA. System memories are SDRAMs. The DOM is a
Disk-On-Module that stores the system software and test data. The RTC is a real time clock.
System configurations are stored in the EEPROM. The VRAM is the memory for video
display.
To monitor such system status as the +48V, +12V and -12V supplies of the analog board,
the +3.3V and +12V supplies of the CPU board itself and the temperature of the whole
1-1
Hardware
analyzer.
To receive the keypad signal and control the keypad buzzer and LCD backlight.
To generate control signals to control the valves, aperture zapping, HGB LED, current
source and digital pot.
1-2
Hardware
1.1.4 RTC
The X1, X4 and X2 are external crystal oscillators whose frequencies are 45MHz, 45MHz and
24MHz respectively. The clock output of the CPU, BCLKO, is main clock signal of the CPU
board.
1-3
Hardware
1.1.6 CPU
The CPU is MOTOROLA MCF5307 (external frequency 45MHz; operation frequency
90MHz; processing speed as high as 75MIPS).
The MCF5307 features a 32-bit data bus and a 32-bit address bus. The board uses a
24-bit addressing mode, reserving the most-significant 8 bits as the general purpose
I/Os for the FPGA.
The MCF5307 can be tuned through the BDM port (J18 of the CPU board).
2
The CPU board utilizes the built-in I C and UART controllers of the MCF5307 to use the
EEPROM and RTC as expanded serials ports.
The CPU boards utilizes the built-in DRMA controller of the MCF5307 to use the 28M
SDRAM as the expanded memory.
1.1.7 WDT
The Watch-Dog-Timer (WDT) is TI TPS3828. It monitors the running of the software. The
CPU must send a feedback to the WDT every 1.6s, otherwise the WDT will force the CPU to
restart.
1-4
Hardware
1.1.8 FLASH
The FLASH is TE28F160(2M bytes). The boot program is stored in the FLASH, so the
FLASH is also called the BootROM. Every time the system is powered on, the CPU first
executes the boot program that initializes the system and loads the control software from the
DOM. The FLASH also contains such information as the FPGA configuration, FPGA version
and LCD contrast.
1.1.9 SDRAM
The system memory consists of two 8M-byte memories.
1.1.10 DOM
The CPU board uses a 32M DOM that is powered by a 3.3V supply (the DOM can also be
supplied by 5V supply). The DOM is only operational after the FPGA is configured.
1.1.11 RTC
The CPU board uses a real time clock (RTC) to record the time. The RTC is connected to the
I2C bus of the CPU board and synchronized by a 32.768KHz crystal oscillator. When the
analyzer is powered on, the RTC is powered by the CPU board; when the analyzer is
powered off, it is powered by the built-in battery.
1.1.12 EEPROM
The CPU board uses an 8K byte EEPROM to store such information as system
configurations and settings. It is connected to the I2C bus of the CPU and can be written by
CPU on-line.
1.1.13 LEDs
When D1 is on, it means +3.3V is functioning properly. When D9 is on, it means +12.8V is
functioning properly. When D5 is on, it means the system is reading or writing the DOM.
1-5
Hardware
When D7 is on, it means the FPGA has been configured and is functioning properly. When
D20 is on, it means the FPGA is restarting; The D11D18 indicate the system status as
defined by the software.
Serial Port
The analyzer has 6 serial ports, which are illustrated in Figure 1-6.
1-6
Hardware
The CPU incorporates 2 UART controllers (3.3LVTTL), one to control the motor of the driving
board and the other communicates with the recorder (powered by 5VTTL). The FPGA
implements 2 UART (3.3VTTL), one to connect the keypad and the other reserved to control
the pump. Another 2 UARTs (RS232) are implemented inside the Super I/O to connect the
scanner and to communicate with the PC.
The Super I/O provides a keyboard interface and a mouse interface (COM3 and COM4).
Note that the BC-2800VET does not support the mouse yet.
1.1.18 GPIOs
Signals of the Start key
The FPGA detects the input signal, which will turn low when the Start key is pressed.
The FPGA detects the signals sent by the start transducer and the end transducer.
Digital pot
The SPI bus interface implemented by the FPGA controls the 4 digital potential-meters on the
analog board to control the HGB gain.
The Super I/O outputs 20 control signals to control the valves and pumps through the driving
board. Since the BC-2800VET only has 1 pump and 11 valves, the redundant lines and ports
are reserved.
The Super I/O outputs 4 control signals (through the analog board) to control the three
switches that respectively control the aperture zapping, current source and HGB LED.
Others
The Super I/O outputs 2 control signals to control the photo-couplers of the volumetric
metering board and the buzzer of the keypad.
1-7
Hardware
Power block
The power block includes a 5V, 12V and 30V DC supply. The 12V and 30V supply comes
from the power interfaces, where two LEDs are installed to respectively indicate the whether
the 12V or 30V supply is connected. When the LED is on, it indicates the corresponding
power has been connected to the driving board. The MC7805T converts the received 12V
supply into the 5V supply, as the following figure shows.
12V 5V
MC7805T
Switching block
The switching block mainly consists the photo coupling circuit and driving circuit of the pumps
and valves, as the figure below shows.
Photocoupling circuit
The photocoupling circuit mainly consists of the photocoupler and resistors. It provides 16
1-8
Hardware
TTL outputs to the valves and pumps. The photocoupler, TLP521-2, isolates the digital
ground from the driving ground.
The driving voltage of the valves and pumps are 12V (TTL). The circuit mainly consists of
ULN2068. In the BC-2800VET, the circuit can maximum drives 14 valves and 2 pumps. The
fluidic system decides which pumps or valves are to be actually used.
Since the CPU board requires a 3.3V power supply while the driving board requires a 5V
power supply, a photocoupler (H11L1) is needed for the purposes of conversion and isolation.
The control/Drive circuit of sample probe mechanism includes the control/drive circuit of the
elevator motor and that of the rotation motor. The control system of the sample probe motor
consists of a AT89S51 MCU and ADM705 WDT. The AT89S51 also detects the signals
coming from the position sensor when controlling the motors.
The MCU system provides the sequence signals for the elevator and rotation motors and
controls the position sensors, as the figure below shows. The MCU reset signal (RST_XY) is
active-high.
The drive part mainly consists of a control device (L6506), drive device (L298N) and
follow-current device (UC3610). The drive voltage is 30V. The sequence signal and the
enable signal of the drive device come from the MCU.
1-9
Hardware
The circuit mainly consists of a control part (MCU system) and a drive part.
The MCU is the P87LPC762 with built-in WDT. The MCU system executes the aspirating and
dispensing operation of the syringe and detects the signals sent by the position transducers.
The drive part is similar to that of the elevator motor. See the block diagram above for details.
The control system judges the motor positions by the signals sent by the position transducers
(photocouplers). The photocouplers are driven by the MCU through a 74LS07. The
photocoupler sends the position signals to the MCU through a 74LS14 (inverter). See the
figure below for the block diagram of the position-detecting circuit. The photocouplers are
installed on the sample probe assembly and the syringe assembly and feed the control and
feedback signals to the driving board through cables.
Testable Signals
To test the signals, connect the grounding terminals of the oscillator and the multi-meter to
the DGND or the PGND.
The testable signals are: control signals of valves and pumps, sequence signals of the motors,
valves, position signals sent by the position transducers, serial communication signals, reset
signals and voltage signals of the power supplies.
1-10
Hardware
1-11
Hardware
1-12
Hardware
The keypad adapter scans the keypad and reports the scanned key code to the main board.
The keypad adapter receives the instructions from the main board to turn on/off the backlights
and power indicator of the LCD and to control the brightness of the backlights.
The keypad adapter receives the instructions from the main board to turn on/off the buzzer.
Power supply
The main board provides a +12V and 3.3V supplies, which are isolated from each other.
The 3.3V supply is the main power of the adapter and the +12V is passed to the backlight
board (inverter) of the LCD and also converted to a 5V supply to drive the buzzer and controls
the on/off of the backlight power the adapter. Since the 3.3V and +12V are isolated, the MCU
send the control signals to the buzzer and backlight board through photocouplers.
MCU
The MCU is AT89C2051 whose resetting time is 470ms. It uses a 11.0592MHz crystal
oscillator.
Keypad scanning
The keypad matrix is 5X4 one, incorporating 9 I/O wires and 20 keys. Note that the keys at
line 5 and columns 3 and 4 are not used.
Backlight control
The keypad adapter shuts off the backlight and blinks the power indicator when instructed by
the main board to do so (usually after the analyzer entered the screen saver). The backlight
board uses an independent 12V power supply and receives the control signals through
photocouplers. The transistor is used to help control the LED so that the power indicator can
be turned on even when something is wrong with the MCU.
1-13
Hardware
The LCD brightness is controlled by pot RV1. Adjusting the RV1 can force the VBL to change
within 0.5~3V. The voltage change is fed into the inverter and causes the change of the drive
current and hence the change of the brightness. Note that the smaller the voltage and the
brighter the LCD.
Buzzer control
The buzzer is controlled by a DC signal (5V DC; current<40mA). The 5V supply of the buzzer
is isolated from the VDD and the control signal is received through a photocoupler
TLP521-2that is controlled by a current around 10mA.
1-14
2 Fluidic System
2.1 Functions
prepares diluent for the whole blood and prediluted modes
dispenses diluent
controls vacuum/pressure
2-1
Fluidic System
2-2
Fluidic System
2-3
Fluidic System
The fluidic system consists of the following subsystems: sensor subsystem, bath subsystem,
lyse dispensing and mixing subsystem, diluting subsystem, volumetric metering subsystem,
vacuum subsystem, pressure subsystem and auxiliary subsystem.
The key components of the fluidic system are the solenoid valve, syringe, aperture, sample
probe, pump, bathmetering tube, probe module, negative/positive pressure chamber and
hose.
The solenoid valve is ASCO458. Totally 11 valves are used, 7 three-way valves and 4
two-way valves.
The two syringes, 10mL and 50uL, are made by Mindray.
The aperture is 80.
The sample probe has two layers and its surface is polished, making the probe easy to clean.
2-4
Fluidic System
The fluidic system can be divided into the following functional modules: aspiration/dispensing
module, counting module, washing module, hydraulic module, mixing module and waste
discharging module. See the figure below for the interaction of these modules.
Reagent
Washing Counting
Quantification
module module
Mixing
module Sample
Hydraulic
module
Waste
discharging
module
2-5
Fluidic System
Buffer
tubing
NC NC
C NC C NO C NC NO
1 3 4 5
NO Buffer NO C
tubing
C
NO
2
NC
Probe
50uL 10mL
Wipe
Diluent entrance
Syringe
assembly
The lyse is aspirated and dispensed into the bath as described below:
The valves 1, 3 and 5 are open and the motor pulls the syringe plunger downward to aspirate
certain amount of lyse. The aspirated lyse is stored in the buffer tubing of valves 1 and 3.
Then valve 1 is closed and the motor runs reversely to push the syringe plunger upward to
dispense the stored lyse into the bath.
Since the capacity of the buffer tubing is far greater than the volume of the aspirated lyse, the
lyse will not overflow to the syringes through valves 3 and 4.
Service tip: Note that the length and type of the buffer tubing shall not be changed.
2-6
Fluidic System
Aerial dust
1 2 filter
Metering
tube
Aperture
Negative Pressure
Front chamber
bath
Back
bath
The counting module is implements the most important function of the analyzer - counting.
The electrodes installed on the bath detect the pulses caused by blood cells passing the
aperture. The detected pulses are then sent to the analog board to be amplified, rectified,
recognized, adjusted and counted.
When the sample is mixed in the bath, valve 2 is open and the negative pressure chamber
introduces the atmospheric air to pass through the filter and valve 2 and then to flush the
metering tube. Valve 1 is open when the vacuum has been established and the sample
(blood cells) in the bath is drawn through the aperture by the negative pressure to generate
the counting pulses. The sample keeps moving to push the rinse between the back bath and
metering tube to move through the tube. When the rinse passes the upper optical sensor
mounted on the metering tube, a start signal is generated and sent to the analog board,
which starts the counting right away, and when the rinse passes the lower optical sensor, a
stop signal is generated and sent to the analog board, which stops the counting right away.
Volumetric metering: the volumetric metering ensures a relatively objective and stable
analysis cycle.
Monitoring of the counting time: the volumetric metering enables the monitoring of the
2-7
Fluidic System
counting time. By monitoring the counting time, the system can easily know whether the
aperture is clean or blocked and feed this information to the service personnel in terms of the
aperture voltage so that they can service the analyzer in time.
The part that washes the sample probe is shown in Figure2-5. The washing consists of two
procedures washing the exterior and washing the interior.
To wash the exteriorThe plunger of the 10mL syringe moves downward to aspirate diluent
from the NO end of valve 6. Then the plunger moves upward and valves 6 and 5 are open so
that the aspirated diluent is dispensed, through the NC end of valve 6, NC end of valve 5 and
valves 4 and 3 to the lower part of the probe wipe. Then the pump functions to open valves 9
and 10 to introduce a negative pressure on the upper part of the probe wipe. Because of this
negative pressure, the diluent dispensed to the lower part of the probe wipe is transferred to
the upper part and washes the exterior through the up-and-down movement of the sample
probe.
To wash the interior: The plunger of the 10mL syringe moves downward to aspirate diluent
from the NO end of valve 6.Then the plunger moves upward to dispense the aspirated diluent,
through valves 5 and 6 and the buffer tubing, to the sample probe to wash the interior.
2-8
Fluidic System
Buffer
tubing
NC
NC C NO C NC NO
3 4 5
NO C
C
NO
2
NC
50uL 10mL
NO
Waste exit
9
NC
Pump C
Probe NO
Wipe
Syringe
8
C
assembly NC
Sample
probe
The part that washes the baths is shown in Figure 2-6. The washing consists of two
procedures: washing the front bath and washing the back bath. The front bath is washed by
diluent and the back bath by rinse. The diluent and the rinse are different and cannot replace
each other.
2-9
Fluidic System
Aerial dust
C C filter
C Metering
tube
50uL 10mL
Dispensing Negative
tube pressure chamber
Syringe
assembly
Rinse
entrance
Figure 2-6 Washing module of fluidic systemwashing of front and back baths
The hydraulic module is shown in Figure 2-7. This module serves to establish the vacuum
and the positive pressure.
To establish the positive pressure: When both valve 1 and the pump are open, the pump
sucks atmospheric air into it, through the upper port and the NC end of valve 1. The sucked
pressure is stored in the pressure chamber to establish the positive pressure. The pressure
value is monitored by the pressure sensor.
To establish the vacuum: When both valve 2 and the pump are open, the liquid and air in the
pressure chamber is expelled to the outside through the NO end of valve 1 and the pump and
the NC end of valve 2 to establish the vacuum. The pressure value is monitored by the
pressure sensor.
2-10
Fluidic System
Pressure Pressure
sensor sensor
NO NO
Waste exit Waste exit
2 2
NC NC
Pump Pump C
C
NO NO
1 1
C C
Probe Wipe NC Probe Wipe NC
the left establishes the pressure; the right establishes the vacuum
The on/off interval of the valve is critical to effect of the bubble mixing. Either too many or too
few bubbles will affect the mixing. During the mixing process, the airway should be well
drained, or the trapped liquid will affect the quantity of the bubbles as well as the dilution.
2-11
Fluidic System
Positive pressure
Bath
assembly Mixing
bubbles
Negative pressure
chamber
Bath
assembly Negative pressure
chamber
11
NO
Waste exit
10
NC
Pump C
Probe
Wipe NO
9
C
NC
2-12
3 Disassembling the Analyzer
3-1
Disassembling the Analyzer
3-2
Disassembling the Analyzer
3-3
Disassembling the Analyzer
3.2.2 Removing the back plate and the fixing plate of the
power module
As the figure below shows, remove the retaining screws (totally 10) to remove the plates.
3-4
Disassembling the Analyzer
Figure 3-5 Removing the back plate and the fixing plate of the power module
3-5
Disassembling the Analyzer
3-6
Disassembling the Analyzer
3-7
Disassembling the Analyzer
3-8
Disassembling the Analyzer
3-9
Disassembling the Analyzer
As the figure below shows, remove the retaining screws (4 for each part) to remove the
assembly.
3-10
Disassembling the Analyzer
Figure 3-16 Removing the vacuum chamber and volumetric metering tube assembly
z The sample probe tip is sharp and may contain biohazardous materials.
Exercise caution to avoid contact with the probe when working around it.
The relative position between the sample probe and probe wipe block has influence on the
analysis results. In the accessory box, there is a sample probe localizer, as Figure 3-17
shows. You need to use the localizer to adjust the position of the sample probe if you have
replaced wipe block, or observed motor error, or wrong analysis result. Also, as required by
regular maintenance, you should use the localizer to adjust the position of the sample probe
monthly.
3-11
Disassembling the Analyzer
3. Follow the arrow shown into push and remove the right plate;
4. Press [F1] to select the Machine group and SELECT Elevator motor, as Figure 3-20
shows;
3-12
Disassembling the Analyzer
6. Press [] to move the sample probe upward and press [] to move the probe to above
the bath, as Figure 3-22 shows;
3-13
Disassembling the Analyzer
8. Remove the probe from the wipe block and insert the localizer into the wipe block from
the bottom, as Figure 3-24 shows;
3-14
Disassembling the Analyzer
9. Insert the probe into the wipe block until it reaches the localizer, as Figure 3-25 shows;
10. Retighten the screw to fix the probe and remove the localizer to wrap up the adjustment.
3-15
4 Pulse Graphs
After each count, the system can save the original sampling pulses of this time. We can
analyze the reason leading to the fault by viewing these original data.
When the instrument is working normally, the length of pulse data is related to the
concentration of the blood sample. The length of the pulse data should be within a limit range.
For general samples, the range should be: WBC: < 1M, RBC: < 600K, PLT: < 1M. Data
length of abnormal sample will not lie in this range.
Length of normal level controls data should be:
WBC: 400 ~ 700K, RBC250 ~ 450K, PLT300 ~ 600K
Figure 4-1 WBC pulse graph of normal Figure 4-2 Pulse graph of normal WBC
sample background
4-1
Pulse Graphs
Figure 4-3 RBC pulse graph of normal Figure 4-4 Pulse graph of normal RBC
sample background
Figure 4-5 PLT pulse graph of normal Figure 4-6 Pulse graph of normal PLT
sample background
4-2
Pulse Graphs
Figure 4-8 Severe interference in WBC Figure 4-9 Severe interference in WBC
channel (Background) channel (Normal sample)
Figure 4-10 Severe interference in RBC Figure 4-11 Severe interference in RBC
channel(Background) channel (Normal sample)
Figure 4-12 Severe interference in PLT Figure 4-13 Severe interference in PLT
channel(Background) channel(Normal sample)
4-3
Pulse Graphs
Figure 4-14 Interference occurs because Figure 4-15 Interference occurs because
gain of PLT channel is too large gain of PLT channel is too large
(Background) (Normal sample)
Figure 4-18 Slight interference in RBC Figure 4-19 Sample of too dense
channel(Normal sample) concentration in RBC channel
( Does not occur in normal situation )
Figure 4-20 Slight interference in PLT Figure 4-21 Sample of too dense
channel(Normal sample) concentration in PLT channel
(Does not occur in normal situation)
4-4
Pulse Graphs
Figure 4-22 Interference in WBC channel Figure 4-23 Measuring interference from
caused by inverter inverter
Feature: sine wave with cycle of 20
26us
Figure 4-24 Insufficient liquid in WBC Figure 4-25 Interference in RBC channel
bath during count from tubing
Feature: data length increases, the base
line of signal is not stabile.
Figure 4-26 Insufficient liquid in RBC Figure 4-27 Interference in PLT channel
bath during count from tubing
Feature: data length increases, the base
line of signal is not stabile.
4-5
Pulse Graphs
Figure 4-28 Insufficient liquid in PLT Figure 4-29 Interference in WBC channel
bath during count from tubing
Feature: data length increases, the base
line of signal is not stabile.
4-6
5 Maintenance
Regular cleaning and maintenance are demanded to guarantee this analyzer operating
properly. This chapter introduces how to take care of this analyzer and check the system
status.
Liquid overflow or leak during the operation of this analyzer will degrade the accuracy of the
analysis results. Once it occurs, immediately wipe off the spills. If it occurs inside this analyzer,
be sure to shut down the power immediately and call Mindray Customer Services Department
or the distributor. Otherwise, the service life of this analyzer may be shortened.
z Do not perform any maintenance procedures that are not described in this
chapter. Performing unauthorized maintenance procedures can damage
your analyzer.
5-1
Maintenance
Everyday If you are to use this analyzer 24 hours a day, be sure to perform
the E-Z cleanser cleaning procedure everyday.
Run the QC program everyday. See Chapter 8 Using the QC
Programs for details.
Every three days If you are to use this analyzer 24 hours a day, be sure to perform
the Probe cleanser cleaning procedure every three days.
Every Week If you shut down your analyzer every day and follow the specified
shutdown procedure to do that, you need to perform the Probe
cleanser cleaning procedure every week.
Every Month You should use the supplied probe localizer to calibrate the
position of the probe to that of the probe wipe. The analysis result
is sensitive to their alignment.
As needed When you think the bath might be contaminated, perform the
Clean the bath procedure.
When the analyzed samples add up to 100, the analyzer will
remind you to perform the Probe cleanser cleaning procedure.
When the analyzed samples add up to 100, the analyzer will
remind you to perform the E-Z cleanser cleaning procedure.
When the analyzed samples add up to 4,000, the analyzer will
remind you to perform the Clean wipe block procedure.
When this analyzer is not to be used for two weeks, be sure to
perform the Prepare to ship procedure to empty and wash the
fluidic lines and then wipe the analyzer dry and wrap it up for
storage.
To obtain reliable analysis results, this analyzer needs to work in a
normal status. Be sure to run the Self-test items regularly to
check the status of this analyzer.
When this analyzer gives alarms for clogging, you can perform the
Flush aperture or Zap aperture procedure, or press [F2] to
unclog the aperture.
If you see other error messages, see Chapter 11
Troubleshooting Your Analyzer for solutions.
5-2
Maintenance
Rinse Prime
Lyse Prime
Zap Aperture
Flush Aperture
Lyse Test
Clean Bath
Drain Bath
Drain Tubing
Prepare to ship
z The reagents are irritating to eyes, skin and diaphragm. Wear proper
personal protective equipment (e.g. gloves, lab coat, etc.) and follow safe
laboratory procedures when handling them in the laboratory.
z If the reagents accidentally spill on your skin, wash them off with plenty of
water and if necessary, go see a doctor; if the reagents accidentally spill into
your eyes, wash them off with plenty of water and immediately go see a
doctor.
z After installing a new container of reagents, keep the reagents still for a
while before using them.
You should perform the Diluent prime procedure to prime the diluent tubing with diluent
when
5-3
Maintenance
you have installed a new container of diluent without shutting the analyzer.
At the Maintenance screen, SELECT Diluent prime to prime the tubing with diluent and
the priming progress will be displayed at the bottom of the screen, Figure 5-1 shows. When
the priming is done, the screen will return to the initial state.
z The reagents are irritating to eyes, skin and diaphragm. Wear proper
personal protective equipment (e.g. gloves, lab coat, etc.) and follow safe
laboratory procedures when handling them in the laboratory.
z If the reagents accidentally spill on your skin, wash them off with plenty of
water and if necessary, go see a doctor; if the reagents accidentally spill into
your eyes, wash them off with plenty of water and immediately go see a
doctor.
z After installing a new container of reagents, keep the reagents still for a
while before using them.
5-4
Maintenance
You should perform the Rinse prime procedure to prime the rinse tubing with rinse when
there are bubbles in the tubing; or
you have installed a new container of rinse without shutting the analyzer.
At the Maintenance screen, SELECT Rinse prime to prime the tubing with rinse and the
priming progress will be displayed at the bottom of the screen, as Figure 5-2 shows. When
the priming is done, the screen will return to the initial state.
5-5
Maintenance
z Be sure to keep the reagents still for a while before using them. After
installing a new container of reagents, keep the reagents still for a while
before using them.
You should perform the Lyse prime procedure to prime the lyse tubing with lyse when
there are bubbles in the tubing; or
you have installed a new container of lyse without shutting the analyzer.
At the Maintenance screen, SELECT Lyse prime to prime the tubing with lyse and the
priming progress will be displayed at the bottom of the screen, as Figure 5-3 shows. When
the priming is done, the screen will return to the initial state.
At the Maintenance screen, SELECT Zap aperture to zap the apertures and the zapping
progress will be displayed at the bottom of the screen, as Figure 5-4 shows. When the
zapping is done, the screen will return to the initial state.
5-6
Maintenance
At the Maintenance screen, SELECT Flush aperture to flush the aperture and the
flushing progress will be displayed at the bottom of the screen, as Figure 5-5 shows. When
the flushing is done, the screen will return to the initial state.
5-7
Maintenance
You can soak the bath and fluidic lines with the probe cleanser, an alkaline detergent, by
performing the Probe cleanser cleaning procedure. If your analyzer is to run 24 hours a
day, you should perform this procedure every 3 days. If you follow the shutdown procedure to
turn off your analyzer everyday, you should perform this procedure every week.
2. Present the cleanser to the probe and press [ENTER] to aspirate the cleanser. When you
hear the beep and the sample probe is out of the bottle, remove the cleanser. The
analyzer will start priming process, as Figure 5-6 shows;
3. When the priming is done, the analyzer will start the 5-minute soaking process, as Figure
5-7 shows and you may press [ENTER] to stop it before the time is due. Note that a
5-8
Maintenance
4. When the soaking is done, the analyzer will start the cleaning process, as Figure 5-8
shows, after which screen will return to the initial state;
To make sure this analyzer functions normally, every time the accumulated analyzed samples
reach 100, a message box will pop up to remind you to perform the probe cleanser
cleaning procedure, as Figure 5-9 shows. CLICK Yes to proceed with the cleaning; CLICK
No to cancel the cleaning.
5-9
Maintenance
You can use the E-Z cleanser, an enzyme based, isotonic cleaning solution and wetting agent,
to clean the tubing and bath by performing the E-Z Cleanser Cleaning procedure.
Follow the steps given below to perform the procedure:
2. Present the cleanser to the probe and press [ENTER] to aspirate the cleanser. When you
hear the beep and the sample probe is out of the bottle, remove the cleanser. This
analyzer will automatically prime the bath and fluidic lines with the aspirated cleanser and
the progress is displayed on the screen, as Figure 5-10 shows;
5-10
Maintenance
3. When the priming is done, the analyzer will start the 10-minute soaking process, as
Figure 5-11 shows.
4. When the soaking is done, the analyzer will start the draining process, as Figure 5-12
shows. When the draining is done, the whole procedure is over and the screen will return
to the initial state.
If your analyzer has been running continuously for 24 hours, a dialog box, as Figure 5-13
shows, will pop up to remind you to perform the E-Z cleanser cleaning procedure. If you
want to do so, CLICK Yes . Otherwise, CLICK No to cancel the cleaning.
5-11
Maintenance
z The reagents are irritating to eyes, skin and diaphragm. Wear proper
personal protective equipment (e.g. gloves, lab coat, etc.) and follow safe
laboratory procedures when handling them in the laboratory.
z If the reagents accidentally spill on your skin, wash them off with plenty of
water and if necessary, go see a doctor; if the reagents accidentally spill into
your eyes, wash them off with plenty of water and immediately go see a
doctor.
In case of any abnormal WBC counts or histograms, you can perform the Lyse test
procedure to check whether the lyse can be dispensed properly.
Follow the steps given below to do so:
1. Unscrew and remove the retaining screws with hands or screwdrivers (pointed by the
arrows shown in Figure 5-14) on the right plate;
2. Follow the arrow shown in Figure 5-15 to push and remove the right plate;
5-12
Maintenance
3. Remove the screws fixing the shielding box of the bath, as Figure 5-16 shows;
4. Remove the shielding box to expose the bath, as Figure 5-17 shows;
5-13
Maintenance
5. SELECT Lyse test. The analyzer will automatically drain the bath and then dispense
2ml of lyse into the bath;
6. Check the scale to see whether the lyse has reached the expected line (the second from
the bottom). If so, press [ENTER] and the analyzer will automatically flush the bath and
dispense lyse and the test is done;
7. If not, repeat steps 5 and 6 several times. If all the tries have failed, check whether the
lyse has run out or the lyse pickup tube is not properly connected to this analyzer. If the
lyse is still enough and the tube is well connected to the analyzer, contact the Mindray or
your local distributor for assistance.
SELECT Clean bath to start the cleaning procedure, as Figure 5-18 shows. When the
cleaning is done, the screen will return to the initial state;
5-14
Maintenance
3. When the draining is done, the screen will display the residual time of draining bath;
5-15
Maintenance
4. Check the bath and the tubing below them for residual fluid. If there is no fluid, press
[ENTER] to prime the bath with diluent, as Figure 5-21 shows. When the priming is done,
the screen will return to the initial state;
5. If there is fluid left, turn off the analyzer and call Mindray customer service department or
your local distributor for assistance.
5-16
Maintenance
z The reagents are irritating to eyes, skin and diaphragm. Wear proper
personal protective equipment (e.g. gloves, lab coat, etc.) and follow safe
laboratory procedures when handling them in the laboratory.
z If the reagents accidentally spill on your skin, wash them off with plenty of
water and if necessary, go see a doctor; if the reagents accidentally spill into
your eyes, wash them off with plenty of water and immediately go see a
doctor.
You can perform the Drain tubing procedure to drain the fluidic system. Follow the steps
given below to do so
1. Press the appropriate arrow keys ([][] [][]) as needed to move the cursor to Drain
tubing;
2. Remove the diluent, rinse and lyse pickup tubes from the back of the analyzer;
4. When the draining is done, the screen will display Turn off this analyzer and you
should turn off this analyzer as instructed.
5-17
Maintenance
4. Unscrew and remove the retaining screws with hands or screwdrivers (pointed by the
arrows shown in Figure 5-23) on the right plate;
5. Follow the arrow shown in Figure 5-24 to push and remove the right plate;
6. Follow the instructions displayed on the screen to place an empty cup, whose diameter
5-18
Maintenance
7. Press [ENTER] to soak the wipe block with the aspirated cleanser. The soaking progress
will be displayed on the screen, as Figure 5-25 shows;
8. When the soaking is done, wipe the bottom of the wipe block with a probe
cleanser-dipped cloth that does not leave debris;
9. Press [ENTER] to flush the block and the interior of the probe and the flushing progress is
displayed on the screen, as Figure 5-26 shows;
Figure 5-26 Flush the block and the interior of the probe
10. After the flushing is done, the screen returns to the initial state.
When the accumulated analyzed samples reach 4,000, a message box will pop up to remind
to clean the probe wipe, as Figure 5-27 shows. CLICK Yes to do the procedure; CLICK
5-19
Maintenance
1. Press the appropriate arrow keys ([][][][]) to move the cursor toPrepare to ship.
Remove the diluent, rinse and lyse tubing from the containers following the instructions
displayed on the screen;
2. Press [ENTER] and a message box will pop up to ask you to confirm this operation, as
Figure 5-28 shows;
3. CLICK No if you want to abort this operation; CLICK Yes to proceed with the
operation. The analyzer starts to drain the fluidic lines and the progress is displayed on
the screen, as Figure 5-29 shows.
5-20
Maintenance
4. After draining the tubing, follow the instructions displayed on the screen (Figure 5-30) to
put the rinse, diluent and lyse tubing into distilled water and press [ENTER] to flush this
analyzer with the distilled water;
5. When the washing is over, follow the instructions displayed on the screen to remove the
rinse, diluent and lyse tubing from the distilled water and press [ENTER] to drain the
tubing again;
6. Turn off the analyzer when the screen displays Turn off the analyzer;
7. Wipe this analyzer dry and wrap it up for storage.
5-21
Maintenance
The items displayed in the System Status screen reflect how the analyzer is functioning
and contribute significantly to diagnosing analyzer errors. You may follow the instructions
given below to check those items.
Press [MENU] to enter the system menu and SELECT Service Status, as Figure 5-31
shows, to enter the Status screen, as Figure 5-32 shows.
At the Status screen you can only view the displayed status information and reference
ranges without changing them.
5-22
Maintenance
Press [MENU] to enter the system menu and SELECT Service Self-test, as Figure
5-33 shows, to enter the Self-test screen, as Figure 5-34 shows.
This area displays the test groups. The available self-test items are divided into four groups,
Tubing, Machine, Valve and Circuit.
Press [F1] to select the desired group. The selected group is preceded by a .
5-23
Maintenance
This area displays the items included in the test group and the test results.
This area displays useful information to help you move to the next step.
At this screen, if you want to acquire help information, press [HELP]; if you want to print out
the test results (except for the results of the tests), press [PRINT].
Count Time
It measures the duration of a WBC and RBC count, namely how many seconds it takes for
the aspirated fluid flows from the first sensor to the second.
Aperture(v)
It measures the voltage (v) over the aperture.
Vacuum
It checks whether the vacuum system functions normally.
Pressure
It checks whether the system flushes the aperture at a normal pressure.
Filter
It checks whether the filter functions normally.
5-24
Maintenance
To conduct the following tests, SELECT the desired test and the results will be displayed
later.
Syringe motor
The syringe motor controls the aspiration volume. This test checks whether the motor
functions normally.
Rotation motor
The rotation motor rotates the sample probe inside the analyzer. This test checks whether the
motor functions normally.
Elevator motor
The elevator motor controls elevation of the sample probe. This test checks whether the
motor functions normally.
Print
This test checks whether the recorder or printer functions normally. If normal, when you press
[ENTER], the recorder or printer will print out a test page; if abnormal, the screen will display
the corresponding error message and you can see Chapter 11 Troubleshooting Your
Analyzer for solutions.
5-25
Maintenance
To test a valve, SELECT the valve. If the valve goes through an Off-On-Off sequence without
making any abnormal sound, it passes the test. Otherwise, something may be wrong with the
valve.
To conduct the test, SELECT A/D interrupt and the test result will be displayed later.
5-26
Maintenance
5.4 Log
The log records all the major events taking place during the running of this analyzer. It helps
the service engineers diagnose system errors.
Press [MENU] to enter the system menu and SELECT ServiceLog, as Figure 5-38
shows to enter the Log screen, as Figure 5-39 shows.
The recorded events are divided into three groups, All, Settings and Other( including
setting discriminators, system self-test and updating system software), which are all listed on
the left of the screen. All the recorded events are listed on the right of the screen by default.
You can press [F1] to select the interested group and the right of the screen will display the
events of the selected group only. Every screen displays 10 events. You can press [] or []
to check the events one by one or press [PgUp] or [PgDn] to check the events on the
previous or next screen. If you want to print out the displayed events, press [PRINT]. If you
want to acquire help information, press [HELP].
5-27
Maintenance
For every recorded event, the NO. column displays the sequences of the recorded events;
the Time column displays the time when this event occurred; the Type column displays
the event type; the Times column displays how many times (1 to 255) this event occurred
and if it occurred more than 255 times, the excessive events will be recorded from 1 to
another log file; the Informationcolumn displays extra information regarding the event.
This analyzer can save maximum 1000 log files and once the maximum number has been
reached, the newest log will automatically cover the oldest one.
5-28
Maintenance
To view the system configuration, press [MENU] to enter the system menu, and SELECT
ServiceConfig. , as Figure 5-40 shows, to enter the Config. screen, as Figure 5-41
shows.
Every screen displays 13 items and you can press [] or [] to select the item you want to
see, or press [PgUp] or [PgDn] to go to the previous or next screen. If you want to print out
the configuration, press [PRINT]. If you want to acquire help, press [HELP].
5-29
Maintenance
Press the [MENU] to enter the system menu and SELECT ServicePrint. , as Figure 5-42
shows, to enter the Print screen, as Figure 5-43 shows.
The printing tasks are queued in this screen, where you can view the all and delete those
waiting to be processed. Once something goes wrong with the printing device, the task being
processed will be deleted and the queued tasks will keep waiting. Once the system finds the
error has been removed, it will resume printing and process the tasks from the first one. Note
that you cannot change the sequence of the queued tasks.
You can perform the following operations at the Print screen:
Press [DEL] to delete the selected task;
5-30
6 Troubleshooting Your Analyzer
6.1 Introduction
The BC-2800Vet continuously monitors the status of the system and displays pertinent
information in the lower left corner of the Count screen (the Error Message area). If a
problem is detected, the Error Message area displays the corresponding error message. This
chapter contains information that is helpful in locating and correcting problems that may occur
during operation of your analyzer.
z Unless otherwise instructed, always turn off the power before trying to fix
the error.
6-1
Troubleshooting Your Analyzer
Liquid drips Damaged pump hose or blocked 1. Turn off the power and wipe the
from analyzer filter. analyzer dry;
6-2
Troubleshooting Your Analyzer
The analyzer can provide error messages. See the tables below for the error messages and
their probable causes and recommended action. If the problem still remains after you have
tried the recommended solutions, contact Mindray customer service department or your local
distributor.
4.
HGB error 5. HGB blank voltage within 1. Do the Probe Cleanser Cleaning
0 V to 3.2 V or 4.9 V to 5 V. procedure;
6-3
Troubleshooting Your Analyzer
HGB adjust HGB blank voltage within 3.2 1. Do the probe cleanser cleaning
V to 3.4 V or 4.8 V to 4.9 V. procedure;
6-4
Troubleshooting Your Analyzer
WBC bubbles 1. Diluent or rinse running 1. Check if the diluent or rinse has run
out; out. If so, change a new container of
6-5
Troubleshooting Your Analyzer
RBC bubbles 1. Diluent or rinse running 1. Check if the diluent or rinse has run
out; out. If so, change a new container of
Barcode error 1. Poor connection between 1. Check if the analyzer is well connected
the scanner and the to the analyzer;
analyzer; 2. Check if the bar-code is valid;
2. Invalid bar-code. 3. If the problem remains, contact
Mindray customer service department
or your local distributor.
Barcode com Poor connection between the 1. Check if the analyzer is well connected
scanner and the analyzer. to the analyzer;
error
2. If the problem remains, contact
Mindray customer service department
or your local distributor.
6-6
Troubleshooting Your Analyzer
Printer out of Printer paper running out or 1. Check if there is printer paper;
not properly installed.
paper 2. Check if the printer paper is well
installed.
Printer offline Poor connection between the Check if the printer is well connected to the
printer and the analyzer. analyzer.
Recorder com 1. Poor connection between Shut down the analyzer and contact
2. Damaged recorder.
Recorder out of Recorder paper running out 1. Check if the recorder paper has run
or not properly installed. out. If so, install the paper;
paper
2. Check if the recorder paper is properly
installed. If not, re-install the paper;
Recorder too hot Recorder head too hot. Stop using the recorder. If the problem
repeats, contact Mindray customer service
department.
Press bar up Tension lever not replaced. 1. Press the tension lever;
Lyse out Insufficient lyse or wrong lyse 1. Check if there is sufficient lyse left. If
volume setting. so, access Setup Settings
Reagents and adjust the remaining
lyse volume;
Diluent expired Expired diluent or wrong 1. Check if the diluent has expired. If so,
expiration setting change a new container of diluent;
Rinse expired Expired rinse or wrong 1. Check if the rinse has expired. If so,
expiration setting change a new container of rinse;
Lyse expired Expired lyse or wrong 1. Check if the lyse has expired. If so,
expiration setting change a new container of lyse;
6-7
Troubleshooting Your Analyzer
Vacuum filter The air inside the vacuum 1. Enter Service Selftest
chamber is not extracted Tubingto test the filter;
error
within the given time.
2. If the test result is normal, the error will
be removed;
Real-time clock 1. Someone tempered with 1. Enter Setup Settings Date &
error the on-board battery off Time screen and reset the time;
the board; 2. Restart the analyzer after the
2. Something is wrong with adjustment and the time should be
the on-board battery correct;
(poor contact, dead 3. If the problem remains, contact
battery, etc.); Mindray customer service department
3. Damaged real-clock chip. or your local distributor.
photocoupler.
Rotation Motor 1. Jammed sample probe; 1. Open the front door and check if the
Error 2. Poor contact of the signal sample probe is jammed;
Elevator motor 1. Jammed sample probe; 1. Open the front door and check if the
6-8
Troubleshooting Your Analyzer
A/D error Something is wrong with the 1. Enter the Service Self-test
A/D part of the CPU board. Circuit screen to test the A/D
interrupt;
Vacuum error The vacuum degree does not 1. Check whether the external tubing is
reach the expected value pressed;
within the given time.
2. If not, enter Service Self-test
Tubing to check the vacuum;
3. If the test result is normal, the error will
be removed;
Pressure error The pressure inside the 1. Check whether the external tubing is
pressure chamber does not pressed;
reach the expected value
2. If not, enter Service Self-test
within the given time
Tubingscreen to check the pressure.;
Diluent empty Insufficient diluent or wrong 1. Check if there is sufficient diluent left. If
diluent volume setting. so, access Setup Settings
Reagents and adjust the remaining
6-9
Troubleshooting Your Analyzer
Rinse empty Insufficient rinse or wrong 1. Check if there is sufficient rinse left. If
rinse volume setting. so, access Setup Settings
Reagents and adjust the remaining
diluent volume;
Waste full The waste container is full. Empty the waste container and reset
usable volume of the waste container.
File error Something is wrong with the Turn off the power and contact Mindray
analyzers file system. customer service departmentor your local
distributor.
Dynamic Something is wrong with the Turn off the power and contact Mindray
analyzers memory. customer service departmentor your local
memory error
distributor.
Analog power Something is wrong with the Shut down the analyzer and contact
power board. Mindray customer service department or
error
your local distributor.
6-10
7 List of Spare parts
P/N Description
0000-10-10891 Keyboard
0000-10-10907 Disk-on-module (32M)
0010-10-12316 Hitachi STN screen (640X480)
0200-10-05528 Bearing (for syringes)
0200-20-05530 Plunger
1800-30-19455 Indicator board
2000-20-03124 Ruby Red Cell Counter 80um RB-22084
7-1
List of Spare parts
7-2
List of Spare parts
3001-20-07072 Transformer
3001-20-07245 Three-way valve (ASCO)
3001-20-07246 Two-way valve (ASCO)
3001-30-06880 Sample probe assembly
3001-30-07021 Vacuum chamber assembly
900E-10-04913 Inverter
7-3
Appendices
8 Appendices
A Error Code
A-1
Appendices
A-2
P/N: 2810-20-47207(V1.1)