Pharmacology McqNEW 2

Pharmacology MCQs for Evaluating Exam
1. Tranylcypromine with food containing tyramine will cause:

a. Anaphylactic reaction
b. Hypertensive crisis
c. Malabsorption syndrome
d. Hyperaldosteronism
2. Treatment by alpha adrenergic blockers as antihypertensives is limited

because they may cause:
a. Syncope
b. SLE
c. Rebound hypertension
d. Heart failure
3. Large doses of phenylephrine leads to severe hypertension which can be

treated by:
a. Atenolol
b. Propranolol
c. Epinephrine
d. Phentolamine
4. A patient taking minoxidil as antihypertensive may experience:

a. Hirsutism
b. Tachycardia
c. Cough
5. Digitalis toxicity includes all of the following except:

a. Nausea, vomiting
b. Vision abnormalities
c. AV nodal block
d. Constipation
6. The most important cardiotonic compound in digitalis is:

a. Digoxin alkaloid
b. Digoxin glycoside
c. Digoxin aglycone
d. The sugar part
7. Atropine poisoning can be recognized by all of the following except:
a. Dry skin
b. Flushing
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c. Delirium & restlessness
d. Diarrhea
8. Acute anginal attack can be relieved by:
a. Sublingual nitroglycerin
b. Oral isosorbide dinitrate
c. blocker
d. Calcium channel blocker
9. Patients with angina and CHF, the best Calcium channel blocker for them is:
a. Nifedipine
b. Amlodipine
c. Diltiazem
d. Verapamil
10. Antihypertensive vasodilators can cause all of the following except:

a. Reflex tachycardia
b. Orthostatic hypotension
c. Heart block
d. Oedema
11. Side effects of HCTZ include all of the following except:

a. Hyperuricaemia
b. Hyperglycaemia
c. Hypokalaemia
d. Hypocalcaemia
12. Which diuretic may cause systemic acidosis:

a. HCTZ
b. Furosemide
c. Spironolactone
d. Acetazolamide
13. Sulfinpyrazone has the following effect:

a. Uricosuric effect
b. Antiplatelet effect
c. Antianginal
d. Antihypertensive
14. Which is true about neurotransmitters:

a. They are secreted and degraded inside the cell
b. They cause stimulate postsynaptic receptors only
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c. Secreted and degraded outside the cell
d. Synthesized outside the cell
15. Pilocarpine which is instilled into the eye will cause:

a. Mydriasis
b. Miosis
c. Increased IOP
d. Corneal deposits
16. In treatment of rheumatoid arthritis, salicylates provide only:

a. Analgesic effect
b. Analgesic & anti-inflammatory effect
c. Disease modifying effect
d. Immunomodulatory effect
17. Acetaminophen is preferred over aspirin in the following cases Except:

a. Patients taking antiplatelets
b. Young children with high fever (Reye's syndrome)
c. Patients with liver disease
d. Patient with peptic ulcer
18. Which of the following anti-neoplastics is used in rheumatoid arthritis:

a. Methotrexate
b. Cisplatin
c. Vincristine
d. Vinblastine
19. Piroxicam is:

a. Decreases prostaglandin synthesis
b. Taken once daily
c. Usually used as antipyretic
20. Which is not true about naloxone (opoids antagonist)

a. It antagonizes morphine respiratory depressant effect
b. It antagonizes phenobarbitone respiratory depressant effect
c. It precipitates morphine withdrawal symptoms
d. It has a short half life.
21. Oral contraceptives cause all the following S/E except:
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a. Fluid retention
b. Hypertension
c. Constipation
d. Chloasma.
22. Which is not true about Mg(OH)2:

a. It is an antacid
b. It causes constipation
c. It should be given with Al(OH)3
d. It has short duration of action
23. Omeprazole mechanism of action:

a. Proton pump inhibitor H+/K+ pump
b. H2- blocker.
c. Cytoprotective drug (e.g. Sucralfate, carbenoxolone)
d. Prostaglandin analogue (e.g. misoprostol)
24. For mineral oil, which not true:

a. Slowly absorbed from GIT
b. Chronic use may cause deficiency in fat soluble vitamins
c. Used as laxative
d. May decrease contraceptive action of O\C
25. The best for elderly patient with chronic constipation:

a. Stimulant laxative
b. Stool softener
c. Non-pharmacological methods
26. Which drug is used as anthelmentic:

a. Pavomate (Pyruvinium paomate)
b. Metronidazole
c. Secnidazole
d. Amikacin
27. Toxicities of anti-neoplastic chemotherapy include:

a. Alopecia
b. Bone marrow depression
c. Hyperuricaemia
28. Critical period of teratogenecity:

a. The 1st week
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b. 3-8 weeks
c. 3-6 months
d. 6-9 months
29. Calcium sodium edetate is used for:

a. Lead poisoning.
b. Atropine poisoning
c. Cyanide poisoning
d. BDZ overdose
30. BAL (dimercaprol) is an antidote in mercury toxicity due to:

a. Prevent its absorption
b. Formation of ring complex rapidly excreted
c. Antagonize the harmful effects of mercury
31. Which of the following can cause optic nerve damage:

a. Ethanol
b. Methanol
c. Morphine
d. Cannabis
32. The toxicity of methanol is due to:

a. Formation of formaldehyde
b. Formation of acetaldehyde
c. Direct toxic effect
d. adrenergic stimulation
33. Inhalation anaethetics include all of the following except:

a. Halothane
b. Fluothane
c. Midazolam
d. Nitrous oxide
34. Shortest acting barbiturate used as anaethetic:

a. Thiopental
b. Phenobarbitone
c. Phenobarbital
d. Primidone.
35. Drugs which are poorly lipid soluble and ionized at blood pH:
a. Penetrate BBB very rapidly
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b. Can not pass BBB
c. Secreted in high concentration in breast milk
d. Generally are not renally excreted
36. Parkinson disease is characterized by deficiency of:

a. Dopamine in the nigrostriatum
b. Acetylcholine in the basal ganglia
c. Norepinephrine in higher brain centers
d. Serotonin in the reticular formation
37. The action of benztropine in Parkinsonism is:

a. Stimulate dopamine release
b. Anticholinergic effect
c. Dopamine agonist
d. It is converted to dopamine in the brain
38. Drugs that may induce Parkinsonism:
a. Haloperidol
b. Chlorpromazine
c. Benzodiazepines
39. The use of levodopa in Parkinsonism instead of dopamine:
a. Levodopa is more potent than dopamine
b. Levodopa is not susceptible to peripheral degradation
c. Dopamine can not pass BBB
d. Dopamine is not available
40. In status epilepticus, the drug of choice is:
a. Carbamazepine
b. Valproate
c. I.V. diazepam
d. Gabapentin
41. In petit mal epilepsy the drug of choice is:
a. Valproic acid & ethosuximide
b. Phenytoin
c. Phenobarbitone
d. Carbamazepin
42. Shortest acting BDZ:
a. Oxazepam
b. Temazepam
c. Triazolam
d. Diazepam
43. Which antidepressant selectively inhibit serotonin reuptake:
a. Imipramine
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b. Phenelzine
c. Fluvoxamine
d. Alprazolam
44. Which step is not found in phase II metabolism:
a. Glucoronidation
b. Glycine conjucation
c. Sulfoxidation
d. Acetylation
45. Functional group metabolism occurs in:
a. Phase I reaction
b. Phase II reaction
c. Phase III reaction d. Bioactivation
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What are some important considerations when administering drugs that affect blood pressure?

What factors determine a drug's ability to cross the blood-brain barrier?

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Pharmacology MCQs for Evaluating Exam

1. Tranylcypromine with food containing tyramine will cause:

2. Treatment by alpha adrenergic blockers as antihypertensives is limited

3. Large doses of phenylephrine leads to severe hypertension which can be

4. A patient taking minoxidil as antihypertensive may experience:

5. Digitalis toxicity includes all of the following except:

6. The most important cardiotonic compound in digitalis is:

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10. Antihypertensive vasodilators can cause all of the following except:

11. Side effects of HCTZ include all of the following except:

12. Which diuretic may cause systemic acidosis:

13. Sulfinpyrazone has the following effect:

14. Which is true about neurotransmitters:

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15. Pilocarpine which is instilled into the eye will cause:

16. In treatment of rheumatoid arthritis, salicylates provide only:

17. Acetaminophen is preferred over aspirin in the following cases Except:

18. Which of the following anti-neoplastics is used in rheumatoid arthritis:

19. Piroxicam is:

20. Which is not true about naloxone (opoids antagonist)

21. Oral contraceptives cause all the following S/E except:

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22. Which is not true about Mg(OH)2:

23. Omeprazole mechanism of action:

24. For mineral oil, which not true:

25. The best for elderly patient with chronic constipation:

26. Which drug is used as anthelmentic:

27. Toxicities of anti-neoplastic chemotherapy include:

28. Critical period of teratogenecity:

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29. Calcium sodium edetate is used for:

30. BAL (dimercaprol) is an antidote in mercury toxicity due to:

31. Which of the following can cause optic nerve damage:

32. The toxicity of methanol is due to:

33. Inhalation anaethetics include all of the following except:

34. Shortest acting barbiturate used as anaethetic:

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36. Parkinson disease is characterized by deficiency of:

37. The action of benztropine in Parkinsonism is:

Rami Salib 002-012 4024169

Rami Salib 002-012 4024169

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