H

155.16
137.14
His PERIODIC CHART OF AMINO ACIDS D
133.10
115.09
Asp
C6H9N3O2
www.bachem.com C4H7NO4

Histidine Aspartic Acid

R
174.20
156.19
C6H14N4O2
Arg F
165.19
147.18
C9H11NO2
Phe A
89.09
71.08
C3H7NO2
Ala C
121.16
103.14
C3H7NO2S
Cys G
75.07
57.05
C2H5NO2
Gly Q
146.15
128.13
C5H10N2O3
Gln E
147.13
129.11
C5H9NO4
Glu

Arginine Phenylalanine Alanine Cysteine Glycine Glutamine Glutamic Acid

K
146.19
128.17
C6H14N2O2
Lys L
131.18
113.16
C6H13NO2
Leu M
149.21
131.20
C5H11NO2S
Met N
132.12
114.10
C4H8N2O3
Asn S
105.09
87.08
C3H7NO3
Ser Y
181.19
163.17
C9H11NO3
Tyr T
119.12
101.10
C4H9NO3
Thr

Lysine Leucine Methionine Asparagine Serine Tyrosine Threonine

I
131.18
113.16
C6H13NO2
Ile W
204.23
186.21
C11H12N2O2
Trp P
115.13
97.12
C5H9NO2
Pro V
117.15
99.13
C5H11NO2
Val Basic
Non-polar
(hydrophobic)
1-Letter Amino
Acid Code

Relative
S
105.09
87.08
Ser 3-Letter Amino
Acid Code

Polar, uncharged Molecular Mass C3H7NO3

Acidic M r H20
Chemical
Molecular Structure
Formula

Serine Chemical
Isoleucine Tryptophan Proline Valine Name

Common Fmoc-Strategy SPPS* Protecting Groups Absorption and Emission Characteristics of Chromophores and Fluorophores Common Boc-Strategy SPPS* Protecting Groups

FLUOROPHORE Excitation
Wavelength
Emission
Wavelength
Boc
Abz 320 nm 420 nm
Fmoc t-Butyloxycarbonyl
(2-Aminobenzoyl or Anthraniloyl)
9-Fluorenylmethyloxy- M r = 101.13
carbonyl N-Me-Abz 340 - 360 nm 440 - 450 nm
M r = 223.25 (N-Methyl-anthraniloyl)
AFC 395 - 400 nm 495 - 505 nm
(7-Amido-4-trifluoromethylcoumarin)
AMC 360 - 380 nm 440 - 460 nm Tos
(7-Amido-4-methylcoumarin) Tosyl
Trt M r = 155.20
Trityl Dansyl 342 nm 562 nm
M r = 243.32 (5-(Dimethylamino)naphthalene-1-
sulfonyl)
EDANS 340 nm 490 nm
(5-[(2-Aminoethyl)amino] naphthalene- Mbzl
1-sulfonic acid) 4-Methylbenzyl
FITC 490 nm 520 nm M r = 105.16
Pmc (Fluorescein isothiocyanate)
2,2,5,7,8-Pentamethyl-
Mca 325 nm 392 nm
chroman-6-sulfonyl
((7-Methoxycoumarin-4-yl)acetyl)
M r = 267.37
4MNA 335 - 350 nm 410 - 440 nm Bom
(4-Methoxy--naphthylamide) Benzyloxymethyl
NA 320 - 340 nm 410 - 420 nm M r = 121.16
EP 0 293 073 B1 (-Naphthylamide)
US Patent 4,946,971
Trp 280 nm 360 nm
owned by Bachem
(Tryptophan)
2-Chloro-Z
2-Chlorobenzyloxy-

CHROMOPHORE Extinction
Wavelength
Molar Extinction
Coefficient
carbonyl
M r = 169.59
pNA 405 nm 405 nm = 9450 M-1cm-1
tBu (p-Nitroanilide) 410 nm 410 nm = 8800 M-1cm-1
t-Butyl For
M r = 57.12 Values listed are as reported in the literature *SPPS = Solid Phase Peptide Synthesis
Formyl
M r = 29.02
2002899 published by Global Marketing, Bachem Group, March 2016
Copyright by Bachem AG, Switzerland. Reproduction forbidden without permission.

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