Assessing and Managing Suicide
Assessing and Managing Suicide
Assessing and Managing Suicide
Author manuscript
Med Clin North Am. Author manuscript; available in PMC 2018 May 01.
Author Manuscript
cDepartment of Epidemiology, College of Public Health, The University of Iowa, Iowa City, IA, USA
dAbboud Cardiovascular Research Center, The University of Iowa, Iowa City, IA, USA
eSchool of Health Sciences, University of Nottingham, Nottingham, UK
SYNOPSIS
The assessment of suicide risk is a daunting, but increasingly frequent task for the outpatient
practitioner. Guidelines for depression screening identify more individuals at risk for treatment
and mental health resources are not always easily accessible. For those patients identified as in
need of a formal risk assessment, this article reviews established risk and protective factors for
suicide and provides a framework for the assessment and management of individuals at risk of
Author Manuscript
suicide. The assessment should be explicitly documented with a summary of the most relevant
risk/protective factors for that individual with a focus on interventions that may mitigate risk such
as means restriction, psychotherapy and pharmacotherapy for psychiatric disorders or substance
use, hospitalization, and safety planning.
Keywords
Depression; Mental Health; Prevention; Primary Health Care; Risk Assessment; Suicide
INTRODUCTION
Suicide is a complex personal and sociological phenomenon accounting for 1.6% of all
Author Manuscript
deaths in the US. According to the Centers for Disease Control and Prevention (CDC), there
were 42,773 suicides reported in the United States in 2014 (a rate of 13.4/100,000), which
represents a 24% increase since 1999. Suicide is the 10th leading cause of death in all age
groups with approximately 50% of those deaths involving firearms. Firearms account for
55% of suicides in males while poisoning is the most common means of suicide in females.
f
Corresponding Author: J. G. Fiedorowicz, jess-fiedorowicz@uiowa.edu.
Publisher's Disclaimer: This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our
customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of
the resulting proof before it is published in its final citable form. Please note that during the production process errors may be
discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.
Weber et al. Page 2
For those aged 10–34, suicide remains the second leading cause of death behind
Author Manuscript
unintentional injury. For those aged 35–54, it is the fourth leading cause of death in the
United States, killing more people than liver disease, diabetes, stroke, or infection.1
While suicide remains the most common psychiatric emergency encountered by mental
health providers, its management and risk factors are more commonly treated by primary
care providers. Over 90% of individuals who complete suicide will present to their primary
care provider within weeks to months of their death.2–5 A primary care provider with a
practice of approximately 2,000 patients will, on average, lose a patient to suicide every 3
years.6 Growing requirements for depression screening in primary care render screening,
assessing, and managing suicidal ideation and behaviors a more common element of
practice. Yet, a majority of providers fail to screen for suicidal ideation and feel unprepared
to do so. When evaluating standardized patients presenting with depressive symptoms, only
36% of providers screened for suicidal ideation with many potential barriers identified.7
Author Manuscript
Over 40% of patients who present to primary care are hesitant to discuss their depressive
symptoms, noting stigma, belief that depression is not a primary care problem, and belief
that they should be able to control their own symptoms.8 Many providers lack the time,
space, access to subspecialty care, and mental health training to appropriately assess and
manage suicidal patients.9,10 In a study of 50 primary care providers who lost a patient to
suicide, 88% of these patients endorsed suicidal ideation at their last visit, but such
comments were at times felt to be attention-seeking or not significantly different from
baseline. Providers also struggled with limited access to mental health services for their
patients.5 This challenge is also described when working with adolescent populations where
risk factors are often interpreted as attention-seeking or part of normal development. In
younger populations, open communication can be difficult and involving a support system
can be more challenging.11
Author Manuscript
The aforementioned challenges make the process of assessing for suicide risk a daunting
task for the busy practitioner. The purpose of this article is to cogently summarize the latest
evidence and guidelines for suicide risk assessment and management with a focus for
application in busy outpatient settings.
CHALLENGE
Suicidal ideation and behaviors, akin to the symptoms of an acute coronary syndrome or
stroke, require immediate attention. Unlike their vascular emergency counterparts, however,
no evidence-based algorithms exist to reliably assess, manage, and prevent suicide.12 The
low frequency of suicide is partly responsible for this difficulty. Suicides accounted for 1.6%
of all deaths in the US in 2014. Even in higher risk demographic, such as older men, the
Author Manuscript
overall prevalence of suicide is very low, particularly within a narrow time frame. Even
when protocols have been applied to an inpatient psychiatric population with a higher
baseline risk for suicide, positive predictive values remain less than 11%.13 Adding to the
complexity, the impact many of the variables associated with suicide at a population level
may have varied impact at the level of the individual. For instance, marriage is generally
protective of suicide,14 but for a given patient it may be a key stressor driving suicidal
thoughts, the primary reason to not act on suicidal thoughts, and everything in between. This
Med Clin North Am. Author manuscript; available in PMC 2018 May 01.
Weber et al. Page 3
necessitates a contextual model of clinical decision making in what has been called the
“quintessential clinical judgment.”15
Author Manuscript
While our ability to predict suicide may seem grim, there has been increasing evidence that
education of primary care providers, population-based suicide prevention strategies (such as
media desensationalization and gun reform), and collaborative care models can reduce the
rate of suicide through the identification and modification of certain risk factors and limiting
access to lethal means.
MANAGEMENT GOALS
Management of suicide includes screening for suicidal ideation or behaviors, performing an
assessment of the individual’s current risk of imminent harm, and creating a treatment plan
in collaboration with the patient and any involved supports. This process needs to be
Author Manuscript
Screening Goals
The goal of suicide screening is to determine if an actionable risk is present. In a primary
care setting, this screen should be efficient, easily completed by a front-office staff, and have
high sensitivity (or low false negative rate).16
How to Screen
The Patient Health Questionaire-9 (PHQ-9) is a quick, subjective reporting scale that can
be incorporated into the medical record. Affirmative responses to item 9 regarding thoughts
of death or self-harm have a hazard ratios of 10 and 8.5 for attempts and deaths in a
Author Manuscript
community setting, respectively.17 It is in the public domain and available with instructions
through the Substance Abuse and Mental Health Services Administration (SAMSHA)
website (www.integration.samhsa.gov/images/res/PHQ%20-%20Questions.pdf). While
many clinics defer to the PHQ-2 for depression screening, the cut-off for further depression
assessment is typically three and can miss 50–60% of patients who would otherwise endorse
suicidal ideation on item 9 of the extended version.18
The Columbia Suicide Severity Rating Scale (C-SSRS) is a public forum questionnaire
that can help screen for suicide and form a detailed account of an individual’s suicidal
ideations or behaviors. It is easy to administer with minimal training, available in multiple
languages, and easily included in an electronic medical record. In studies, it has reported
sensitivity of 67%, specifically of 76%, positive predictive values of 14%, and negative
Author Manuscript
Table 1 includes types of screening questions that can help identify current suicide risk
factors and depressive symptoms while enabling the general practitioner to discuss sensitive
topics in an honest and comfortable environment.21
Med Clin North Am. Author manuscript; available in PMC 2018 May 01.
Weber et al. Page 4
Who to Screen
Author Manuscript
There is no current consensus on who should be screened for suicidal ideation or plans. The
World Health Organization (WHO) currently recommends that all individuals over the age
of 10 with any mental health disorder, epilepsy, interpersonal conflict, recent severe life
event, or other risk factor for suicide should be asked about thoughts or plans to self-harm or
attempt suicide.20 Similarly, the Joint Commission recommends that all individuals with a
behavioral or emotional disorder be screened for suicide.22 In an updated review, the United
States Protective Task Force (USPTF) found insufficient evidence to recommend suicide
screening for the general population, noting that routine screening does not identify
individuals at risk for suicide more than screening individuals with mental health disorders,
emotional distress, or a history of suicide attempts.23 Only the CDC currently recommends
that all primary physicians screen the general population for both depression and suicide.22
Author Manuscript
• Anxiety or agitation26,27
• Sleep complaints24
Despite concerns reported by both patients and general practitioners, a systematic review
found no significant increase in suicidal ideation or behaviors when patients were asked
about suicide, regardless of age, current level of depression, or history of suicidal behaviors.
31,32
Author Manuscript
Assessment Goals
After screening has identified an individual at risk, a formal suicide risk assessment should
occur with the following goals: identify modifiable and fixed risk factors, identify protective
factors, clarify the current level of suicidal intent and planning, and estimate the current risk
as low, moderate, or high to guide treatment and disposition.
Med Clin North Am. Author manuscript; available in PMC 2018 May 01.
Weber et al. Page 5
How to Assess
Interviews between care providers and suicidal patients need to maintain or enhance the
therapeutic alliance. All assessments should be conducted with curiosity, concern, calmness,
and acceptance of the individual’s current emotional and cognitive state.34 Patients with
Author Manuscript
suicidal ideation may feel hopeless, desperate, or cognitively overwhelmed, interfering with
their ability to comprehend and convey these thoughts to others. Clinicians should stay
attuned to their own reactions that may be non-therapeutic, such as hostility, avoidance of
negative feelings, or the blurring of professional roles, possibly as a way to take on a savior
role.34
Charles Walker Memorial Trust, an interactive, case-based toolkit entitled “The CWMT GP
Toolkit – The Mental Health Consultation (With a Young Person)” is available publicly
and online (http://www.cwmt.org.uk/wp-content/uploads/2014/01/GPToolkit2013.pdf).
Risk Factors
One challenge with suicide risk factor assessment is that many risk factors are static, not
modifiable, and are limited in helping determine who needs higher level of care. In a 1983
study, 30 suicides were documented in 803 veterans considered at high risk based on risk
factors, but another 37 suicides were also completed in those not considered to be high risk
by risk factors.13
In contrast, some risk factors may be more acute or sub-acute in nature, indicating a
Author Manuscript
heightened risk for suicide in the near term.36 Some of these more acute risk factors, referred
to as “warning signs,” were identified by a consensus panel formed by the American
Association of Suicidology (AAS) to help clinicians appreciate what the patient is doing or
saying in the present moment that may acutely increase their risk.37 There is concern that
even in the setting of significant protective factors, acute risk factors can significantly elevate
an individual’s risk for suicide.38
Med Clin North Am. Author manuscript; available in PMC 2018 May 01.
Weber et al. Page 6
Table 3 includes validated risk factors for suicide, separated by those associated with more
Author Manuscript
acute suicide risk. Risk factors with asterisks represent factors that are potentially modifiable
in the immediate clinical setting.
• Prior suicide attempt remains the strongest predictor of future attempts and
completions.39 There is increasing correlation between suicidal ideation and
behaviors, especially for those presenting in an emergency room setting.40,41
Although most individuals who self-harm do not go on to commit suicide,
repeated self-harm even without intention to end life is a predictor of suicide and
is typically present within the 12 months preceding suicide in young people.42,43
It should be noted, though, that over 90% of suicides are completed on the first
or second attempt.44
of means to perform the action, increasing discussion about death, and rehearsal
behaviors.37 There is no documented difference between passive or active
suicidal ideation in suicide course or outcome; as such, both should hold weight
in suicide assessment.45,46
• Stressful life events must be considered within the circumstance and age of the
patient. Common adolescent events include bullying (either as victim or
perpetrator), disciplinary actions, legal issues, school difficulties, romantic break-
ups, assaults, or problems relating to home-life.47,48 For adults, financial
difficulties, relationship losses, unemployment, and intimate partner violence all
increase the risk for suicide attempts.23,49–51 These events may ultimately
resolve with time and action, but during a visit with a primary care provider, they
Author Manuscript
• All psychiatric disorders, with the exception of intellectual disability and later
course dementias, are associated with an increased risk of suicidal ideation,
attempts, and completions.39,52,53 This risk is significantly greater during active
periods of illness and correlates with severity of illness.48,54 Hopelessness in the
setting of depression increases the risk for suicide and is typically modifiable
with treatment of the mental health disorder.25,40
global quality of life assessment scores, and suffer from more physical
impairment.29,53 Similar risk for depression and suicide is also found in
adolescent populations with chronic physical illnesses.56 While some illnesses
cannot be cured, the amount of disability or functioning may be modifiable with
therapy.
Med Clin North Am. Author manuscript; available in PMC 2018 May 01.
Weber et al. Page 7
associated dysfunction, and increasing suicidal ideation may lead to a more acute
suicide risk compared to a previous baseline level of use.37
Protective Factors
Similar to risk factors, most individuals have both modifiable and non-modifiable protective
factors that may be enhanced during periods of acute distress to help prevent against suicide.
The following questions can help elicit these factors:36,61
Author Manuscript
4. What or who do you rely on for support during times like these?
Similar to risk factors, protective factors have to be considered within the context of the
patient. For example, social obligation to a spouse is protective against suicide, but the
presence of high-conflict or violence within the relationship significantly increases suicide
Author Manuscript
remains the leading cause of maternal death in industrialized countries and vigilance in
assessing for ante- and post-partum depression and anxiety cannot be overemphasized.
61,63,64
Suicidal Evaluation
Part of a suicide risk assessment is gaining a very clear understanding of the individual’s
desire to complete suicide, their capability to do so, and their current suicidal intent. Some
questions that can help elicit this information are included below.36,61,65
3. On a scale of 1–10, where would you rate your seriousness or wish to die?
4. Have you tried out any particular method or taken steps in rehearsal for suicide?
Med Clin North Am. Author manuscript; available in PMC 2018 May 01.
Weber et al. Page 8
The overall goal at this point is that the primary care provider has been able to adequately
identify key risk factors, both modifiable and acute, and protective factors in order to rate the
individuals current risk of suicide. This acute, current risk may differ from the patient’s
chronic level of suicide risk, the latter of which is typically based on static demographic
factors that are not modifiable.66 There can be ambiguity around risk factors and what may
define a chronic and hard to manage risk versus an acute risk that must be dealt with
immediately, necessitating clinical judgement. As many assessment and screening tools do,
we propose that overall risk be defined as a manageable three levels (low, medium, or high).
Individuals at the lowest and highest risk may be easiest to identify and those at more
moderate levels of risk may require greater assessment to discern the most appropriate
management strategy.65
Author Manuscript
While most providers may feel the primary purpose of a risk assessment is to determine
disposition (home versus hospital), it should also be used to help guide other interventions,
both pharmacologic and non-pharmacologic, and regardless of setting.
NON-PHARMCOLOGIC INTERVENTIONS
Author Manuscript
Safety Plan
Safety plans are prioritized lists of coping strategies and sources of support used during or
preceding a suicidal crisis.69 Steps in creating a safety plan include:
Med Clin North Am. Author manuscript; available in PMC 2018 May 01.
Weber et al. Page 9
Ideally, these steps should be detailed, written, kept in a personal spot, and followed in a
step-wise fashion until the crisis resolves.70 Safety plans have been shown to reduce suicide
attempts, completions, depressive symptoms, anxiety, and hopelessness within 3 months
compared to interventions without safety plans.71 Safety plans should not be confused with
so called “no-harm” or contracts for safety, which have not been shown to reduce suicide or
suicidal behavior, offering only false reassurance to the provider.47 An example template for
a safety plan can be found online at http://www.sprc.org/sites/default/files/
Brown_StanleySafetyPlanTemplate.pdf
Means Restriction
Access to lethal means of suicide remains a significant risk factor for all age groups and
interventions that minimize these means remain the most impactful form of primary
Author Manuscript
prevention against suicide.47,72 Firearms are of specific importance, as they remain the most
common suicidal method and account for over 50% of suicide-related deaths, following by
suffocation, hanging, poisoning, and overdose.73 If guns remain in the home, they should be
unloaded, locked, and stored separately from ammunition.74 Restricting access to drugs and
alcohol has also been shown to reduce suicide rates, especially when substance abuse is
considered a risk factor or warning sign for the individual.75
Psychotherapy
In a pooled sample of 11 trials, psychotherapy regardless of methodology was shown to
reduce suicide attempts by over 30%.73,76 The most robust literature exists for the ability of
cognitive behavior therapy, dialectical behavioral therapy, and problem-solving therapy to
reduce self-harm, suicide behavior, and suicidal ideation.77–80
Author Manuscript
Follow-up Care
Intensive management that includes weekly follow-up and assertive outreach by clinic
personal after missed appointments has been shown to significantly reduce suicide rates in
the United Kingdom.82 Other follow-up interventions, such as telephone calls, letters, and
post-cards have shown some benefit for reducing repeat suicide attempts.20,83
Author Manuscript
National crisis lines are also effective at reducing an individual’s sense of crisis, confusion,
helplessness, and suicidality. This effect is improved when a standardized suicide risk
assessment algorithm has been implemented.84
Med Clin North Am. Author manuscript; available in PMC 2018 May 01.
Weber et al. Page 10
health providers when they are past their comfort level, following failed response to
Author Manuscript
treatment trials for the psychiatric disorder, if the patient’s suicidal thoughts are persistent, if
there is suspicion for current psychotic symptoms (hallucinations, delusions, disorganized
thinking), or when hospitalization may be warranted.65,85,86
Collaborative care models, which place mental health services within the primary care
setting, also reduce suicidal ideation and depression within primary care populations.87
These models have been shown to be cost-effective and should be advocated for by primary
physicians when possible as they have not been disseminated as widely as evidence would
warrant.
PHARMACOLOGIC INTERVENTION
Because over 90% of patients who complete suicide had a mental health diagnosis at their
Author Manuscript
time of death, aggressive, evidence-based treatment of mental health disorders should also
be discussed during treatment planning.88 Despite concerns about increased suicide risk with
antidepressant medications, which primarily reflects acute increases in suicidal ideation and
attempts in trials of pediatric samples,89 multiple studies have found them protective against
suicidal thoughts, behaviors, and attempts in all age groups, most strongly and consistently
in adults, especially older adults, when used to treat mood and anxiety disorders.90–96
Selective serotonin-reuptake inhibitors (SSRIs) are preferred over tricyclic antidepressants
(TCAs) in suicidal patients due to lower risk in overdose. TCAs and other medications with
elevated risk in overdose should be prescribed in limited supplies while acute suicide risk
remains elevated.20 When indicated, there is evidence supporting a reduction in risk of
suicide for those treated with clozapine or lithium.97 As with psychotherapy, there is
evidence that suicide attempts are increased in the month before treatment, the month after
Author Manuscript
treatment, after discontinuation of medications, and after any dose change. Close follow-up
and monitoring are warranted during treatment.98
Some pharmacologic interventions may be harmful. After adjusting for mental health
diagnoses, a current prescription for any sedative or hypnotic was associated with a four-fold
increase in suicide risk, especially in patients greater than 65 years old.99,100
DOCUMENTATION
Once a suicide risk assessment and treatment plan have been completed, it is important to
document this plan in detail for the protection of both the patient and the healthcare team.
Documentation should include:34
Med Clin North Am. Author manuscript; available in PMC 2018 May 01.
Weber et al. Page 11
• Review of treatment plan agreed upon with the patient, including why this plan
Author Manuscript
provides the safest treatment in the least restrictive environment. Treatment plan
may include:
d. Safety plan creation (make a copy and scan into medical record)
f. Hospitalization
Author Manuscript
• Include plan for follow-up (next appointment, any follow-up phone calls or other
planned out-of-clinic contacts)
The goal of documentation is to clarify the clinical reasoning behind the assessment with a
plan that logically follows. From a medicolegal perspective, physicians cannot be expected
to predict suicide outcomes, in which high risk individuals may not act and low risk
individuals complete suicide.13,101 While legal standards of care vary, a documented suicide
risk assessment that captures the clinical decision makings should suffice.102 Given the
aforementioned need to contextualize the risk assessment within the story of a particular
patient, the assessment need not list every risk and protective factor, but can highlight those
key risk and protective factors deemed most relevant for the case. Examples of documented
suicide risk assessment can be found in Box 1.
Author Manuscript
FUTURE CONSIDERATIONS/SUMMARY
Suicide risk assessment is distinct from assessing risk for other conditions, such as
Author Manuscript
cardiovascular risk. There are a multitude of factors that must be considered without a clear
algorithm that exists or can be developed. This can prove daunting for many clinicians
without some template for stratification of risk from which to tailor the appropriate
management, but this process is not unlike the many decisions the clinician must make on a
daily basis for which clinical judgement is paramount. Suicide risk assessment similarly
requires the clinician to exercise their clinical judgement and to weigh the relevance of
evidence-based risk and protective factors for the assessment of a particular patient’s risk.
Med Clin North Am. Author manuscript; available in PMC 2018 May 01.
Weber et al. Page 12
Interventions can have a positive impact97 and this review is dedicated to the cadres of
Author Manuscript
clinicians willing to make the effort to save the lives of those suffering so profoundly as to
take their own, at times not even knowing which lives were spared.
References
1. Injury Prevention and Control. 2016
2. Ahmedani BK, Simon GE, Stewart C, et al. Health care contacts in the year before suicide death. J
Gen Intern Med. Jun; 2014 29(6):870–877.
3. Luoma JB, Martin CE, Pearson JL. Contact with mental health and primary care providers before
suicide: a review of the evidence. Am J Psychiatry. Jun; 2002 159(6):909–916. [PubMed:
12042175]
4. Pearson A, Saini P, Da Cruz D, et al. Primary care contact prior to suicide in individuals with mental
illness. Br J Gen Pract. Nov; 2009 59(568):825–832. [PubMed: 19861027]
5. Saini P, Chantler K, Kapur N. General practitioners’ perspectives on primary care consultations for
Author Manuscript
suicidal patients. Health Soc Care Community. May; 2016 24(3):260–269. [PubMed: 25661202]
6. Diekstra RF. Epidemiology of suicide. Encephale. Dec; 1996 22(Spec 4):15–18.
7. Feldman MD, Franks P, Duberstein PR, Vannoy S, Epstein R, Kravitz RL. Let’s not talk about it:
suicide inquiry in primary care. Ann Fam Med. Sep-Oct;2007 5(5):412–418. [PubMed: 17893382]
8. Bell RA, Franks P, Duberstein PR, et al. Suffering in silence: reasons for not disclosing depression
in primary care. Ann Fam Med. Sep-Oct;2011 9(5):439–446. [PubMed: 21911763]
9. Leahy D, Schaffalitzky E, Saunders J, et al. Role of the general practitioner in providing early
intervention for youth mental health: a mixed methods investigation. Early Interv Psychiatry. Dec.
2015
10. Saini P, Windfuhr K, Pearson A, et al. Suicide prevention in primary care: General practitioners’
views on service availability. BMC Res Notes. 2010; 3:246. [PubMed: 20920302]
11. Michail M, Tait L. Exploring general practitioners’ views and experiences on suicide risk
assessment and management of young people in primary care: a qualitative study in the UK. BMJ
Open. 2016; 6(1):e009654.
Author Manuscript
12. Cornette MM, Schlotthauer AE, Berlin JS, et al. The public health approach to reducing suicide:
opportunities for curriculum development in psychiatry residency training programs. Acad
Psychiatry. Oct; 2014 38(5):575–584. [PubMed: 24923779]
13. Pokorny AD. Prediction of suicide in psychiatric patients. Report of a prospective study. Archives
of general psychiatry. Mar; 1983 40(3):249–257. [PubMed: 6830404]
14. Smith JC, Mercy JA, Conn JM. Marital status and the risk of suicide. American journal of public
health. Jan; 1988 78(1):78–80. [PubMed: 3337311]
15. Practice guideline for the assessment and treatment of patients with suicidal behaviors. The
American journal of psychiatry. Nov; 2003 160(11 Suppl):1–60.
16. Crawford MJ, Thana L, Methuen C, et al. Impact of screening for risk of suicide: randomised
controlled trial. Br J Psychiatry. May; 2011 198(5):379–384. [PubMed: 21525521]
17. Simon GE, Coleman KJ, Rossom RC, et al. Risk of suicide attempt and suicide death following
completion of the Patient Health Questionnaire depression module in community practice. J Clin
Psychiatry. Feb; 2016 77(2):221–227. [PubMed: 26930521]
18. Inagaki M, Ohtsuki T, Yonemoto N, et al. Validity of the Patient Health Questionnaire (PHQ)-9 and
Author Manuscript
PHQ-2 in general internal medicine primary care at a Japanese rural hospital: a cross-sectional
study. Gen Hosp Psychiatry. Nov-Dec;2013 35(6):592–597. [PubMed: 24029431]
19. Mundt JC, Greist JH, Jefferson JW, Federico M, Mann JJ, Posner K. Prediction of suicidal
behavior in clinical research by lifetime suicidal ideation and behavior ascertained by the
electronic Columbia-Suicide Severity Rating Scale. J Clin Psychiatry. Sep; 2013 74(9):887–893.
[PubMed: 24107762]
20. Bolton JM, Gunnell D, Turecki G. Suicide risk assessment and intervention in people with mental
illness. BMJ. 2015; 351:h4978. [PubMed: 26552947]
Med Clin North Am. Author manuscript; available in PMC 2018 May 01.
Weber et al. Page 13
21. Carr-Gregg MR, Enderby KC, Grover SR. Risk-taking behaviour of young women in Australia:
screening for health-risk behaviours. Med J Aust. Jun 16; 2003 178(12):601–604. [PubMed:
Author Manuscript
12797844]
22. Bono V, Amendola CL. Primary care assessment of patients at risk for suicide. JAAPA. Dec; 2015
28(12):35–39.
23. O’Connor E, Gaynes BN, Burda BU, Soh C, Whitlock EP. Screening for and treatment of suicide
risk relevant to primary care: a systematic review for the U.S. Preventive Services Task Force. Ann
Intern Med. May 21; 2013 158(10):741–754. [PubMed: 23609101]
24. Denneson LM, Kovas AE, Britton PC, Kaplan MS, McFarland BH, Dobscha SK. Suicide Risk
Documented During Veterans’ Last Veterans Affairs Health Care Contacts Prior to Suicide.
Suicide Life Threat Behav. Feb.2016
25. Morriss R, Kapur N, Byng R. Assessing risk of suicide or self harm in adults. BMJ. 2013;
347:f4572. [PubMed: 23886963]
26. McDowell AK, Lineberry TW, Bostwick JM. Practical suicide-risk management for the busy
primary care physician. Mayo Clin Proc. Aug; 2011 86(8):792–800. [PubMed: 21709131]
27. Dobscha SK, Denneson LM, Kovas AE, et al. Correlates of suicide among veterans treated in
Author Manuscript
primary care: case-control study of a nationally representative sample. J Gen Intern Med. Dec;
2014 29(Suppl 4):853–860. [PubMed: 25355088]
28. Lemieux AM, Saman DM, Lutfiyya MN. Men and suicide in primary care. Dis Mon. Apr; 2014
60(4):155–161. [PubMed: 24726083]
29. Chock MM, Bommersbach TJ, Geske JL, Bostwick JM. Patterns of Health Care Usage in the Year
Before Suicide: A Population-Based Case-Control Study. Mayo Clin Proc. Nov; 2015 90(11):
1475–1481. [PubMed: 26455886]
30. Owens C, Lambert H, Donovan J, Lloyd KR. A qualitative study of help seeking and primary care
consultation prior to suicide. Br J Gen Pract. Jul; 2005 55(516):503–509. [PubMed: 16004734]
31. Bajaj P, Borreani E, Ghosh P, Methuen C, Patel M, Joseph M. Screening for suicidal thoughts in
primary care: the views of patients and general practitioners. Ment Health Fam Med. Dec; 2008
5(4):229–235. [PubMed: 22477874]
32. Dazzi T, Gribble R, Wessely S, Fear NT. Does asking about suicide and related behaviours induce
suicidal ideation? What is the evidence? Psychol Med. Dec; 2014 44(16):3361–3363. [PubMed:
Author Manuscript
24998511]
33. Bernert RA, Hom MA, Roberts LW. A review of multidisciplinary clinical practice guidelines in
suicide prevention: toward an emerging standard in suicide risk assessment and management,
training and practice. Acad Psychiatry. Oct; 2014 38(5):585–592. [PubMed: 25142247]
34. Fowler JC. Suicide risk assessment in clinical practice: pragmatic guidelines for imperfect
assessments. Psychotherapy (Chic). Mar; 2012 49(1):81–90. [PubMed: 22369082]
35. Sanci L, Young D. Engaging the adolescent patient. Aust Fam Physician. Nov; 1995 24(11):2027–
2031. [PubMed: 8579536]
36. Rudd MD, Berman AL, Joiner TE Jr, et al. Warning signs for suicide: theory, research, and clinical
applications. Suicide Life Threat Behav. Jun; 2006 36(3):255–262. [PubMed: 16805653]
37. Rudd MD. Suicide warning signs in clinical practice. Curr Psychiatry Rep. Feb; 2008 10(1):87–90.
[PubMed: 18269900]
38. Berman AL, Silverman MM. Suicide risk assessment and risk formulation part II: Suicide risk
formulation and the determination of levels of risk. Suicide Life Threat Behav. Aug; 2014 44(4):
432–443. [PubMed: 24286521]
Author Manuscript
39. Harris EC, Barraclough B. Suicide as an outcome for mental disorders. A meta-analysis. Br J
Psychiatry. Mar.1997 170:205–228. [PubMed: 9229027]
40. Wang Y, Bhaskaran J, Sareen J, Wang J, Spiwak R, Bolton JM. Predictors of Future Suicide
Attempts Among Individuals Referred to Psychiatric Services in the Emergency Department: A
Longitudinal Study. J Nerv Ment Dis. Jul; 2015 203(7):507–513. [PubMed: 26053262]
41. Younes N, Melchior M, Turbelin C, Blanchon T, Hanslik T, Chee CC. Attempted and completed
suicide in primary care: not what we expected? J Affect Disord. Jan 1.2015 170:150–154.
[PubMed: 25240842]
Med Clin North Am. Author manuscript; available in PMC 2018 May 01.
Weber et al. Page 14
42. Gunnell D, Ho D, Murray V. Medical management of deliberate drug overdose: a neglected area
for suicide prevention? Emerg Med J. Jan; 2004 21(1):35–38. [PubMed: 14734371]
Author Manuscript
43. Hawton K, Houston K, Shepperd R. Suicide in young people. Study of 174 cases, aged under 25
years, based on coroners’ and medical records. Br J Psychiatry. Sep.1999 175:271–276. [PubMed:
10645330]
44. Parra Uribe I, Blasco-Fontecilla H, García-Parés G, et al. Attempted and completed suicide: not
what we expected? J Affect Disord. Sep; 2013 150(3):840–846. [PubMed: 23623420]
45. Schulberg HC, Lee PW, Bruce ML, et al. Suicidal ideation and risk levels among primary care
patients with uncomplicated depression. Ann Fam Med 2005. Nov-Dec;2005 3(6):523–528.
46. Baca-Garcia E, Perez-Rodriguez MM, Oquendo MA, et al. Estimating risk for suicide attempt: are
we asking the right questions? Passive suicidal ideation as a marker for suicidal behavior. Journal
of affective disorders. Nov; 2011 134(1–3):327–332. [PubMed: 21784532]
47. Gray BP, Dihigo SK. Suicide risk assessment in high-risk adolescents. Nurse Pract. Sep; 2015
40(9):30–37. quiz 37–38.
48. Fordwood SR, Asarnow JR, Huizar DP, Reise SP. Suicide attempts among depressed adolescents in
primary care. J Clin Child Adolesc Psychol. Jul-Sep;2007 36(3):392–404. [PubMed: 17658983]
Author Manuscript
49. Cohen A, Chapman BP, Gilman SE, et al. Social inequalities in the occurrence of suicidal ideation
among older primary care patients. Am J Geriatr Psychiatry. Dec; 2010 18(12):1146–1154.
[PubMed: 20808098]
50. Devries KM, Mak JY, Bacchus LJ, et al. Intimate partner violence and incident depressive
symptoms and suicide attempts: a systematic review of longitudinal studies. PLoS Med. 2013;
10(5):e1001439. [PubMed: 23671407]
51. Gallego JA, Rachamallu V, Yuen EY, Fink S, Duque LM, Kane JM. Predictors of suicide attempts
in 3.322 patients with affective disorders and schizophrenia spectrum disorders. Psychiatry Res.
Aug; 2015 228(3):791–796. [PubMed: 26077849]
52. Corson K, Denneson LM, Bair MJ, Helmer DA, Goulet JL, Dobscha SK. Prevalence and correlates
of suicidal ideation among Operation Enduring Freedom and Operation Iraqi Freedom veterans. J
Affect Disord. Jul; 2013 149(1–3):291–298. [PubMed: 23531358]
53. Ashrafioun L, Pigeon WR, Conner KR, Leong SH, Oslin DW. Prevalence and correlates of suicidal
ideation and suicide attempts among veterans in primary care referred for a mental health
Author Manuscript
for bipolar disorder (STEP-BD). Biol Psychiatry. May 1; 2004 55(9):875–881. [PubMed:
15110730]
59. Bjorkenstam C, Andersson G, Dalman C, Cochran S, Kosidou K. Suicide in married couples in
Sweden: Is the risk greater in same-sex couples? European journal of epidemiology. Jul. 2016;
31(7):685–690.
60. Haas AP, Eliason M, Mays VM, et al. Suicide and suicide risk in lesbian, gay, bisexual, and
transgender populations: review and recommendations. Journal of homosexuality. 2011; 58(1):10–
51. [PubMed: 21213174]
Med Clin North Am. Author manuscript; available in PMC 2018 May 01.
Weber et al. Page 15
61. Menon V. Suicide risk assessment and formulation: an update. Asian J Psychiatr. Oct; 2013 6(5):
430–435. [PubMed: 24011694]
Author Manuscript
62. Malone KM, Oquendo MA, Haas GL, Ellis SP, Li S, Mann JJ. Protective factors against suicidal
acts in major depression: reasons for living. Am J Psychiatry. Jul; 2000 157(7):1084–1088.
[PubMed: 10873915]
63. Howard LM, Flach C, Mehay A, Sharp D, Tylee A. The prevalence of suicidal ideation identified
by the Edinburgh Postnatal Depression Scale in postpartum women in primary care: findings from
the RESPOND trial. BMC Pregnancy Childbirth. 2011; 11:57. [PubMed: 21812968]
64. Castro E, Couto T, Brancaglion MY, Cardoso MN, et al. Suicidality among pregnant women in
Brazil: prevalence and risk factors. Arch Womens Ment Health. Apr; 2016 19(2):343–348.
[PubMed: 26189445]
65. Fiedorowicz JG, Weldon K, Bergus G. Determining suicide risk (hint: a screen is not enough). J
Fam Pract. May; 2010 59(5):256–260. [PubMed: 20544044]
66. Bryan CJ, Rudd MD. Advances in the assessment of suicide risk. J Clin Psychol. Feb; 2006 62(2):
185–200. [PubMed: 16342288]
67. Meerwijk EL, Parekh A, Oquendo MA, Allen IE, Franck LS, Lee KA. Direct versus indirect
Author Manuscript
psychosocial and behavioural interventions to prevent suicide and suicide attempts: a systematic
review and meta-analysis. Lancet Psychiatry. Mar.2016
68. Cuijpers P, de Beurs DP, van Spijker BA, Berking M, Andersson G, Kerkhof AJ. The effects of
psychotherapy for adult depression on suicidality and hopelessness: a systematic review and meta-
analysis. J Affect Disord. Jan 25; 2013 144(3):183–190. [PubMed: 22832172]
69. Wilcox HC, Wyman PA. Suicide Prevention Strategies for Improving Population Health. Child
Adolesc Psychiatr Clin N Am. Apr; 2016 25(2):219–233. [PubMed: 26980125]
70. Stanley EY. Safety in action: a practical application. Occup Health Saf. Oct.2012 81(10):52, 54.
71. Wang YC, Hsieh LY, Wang MY, Chou CH, Huang MW, Ko HC. Coping Card Usage can Further
Reduce Suicide Reattempt in Suicide Attempter Case Management Within 3-Month Intervention.
Suicide Life Threat Behav. Feb; 2016 46(1):106–120. [PubMed: 26201436]
72. Mann JJ, Apter A, Bertolote J, et al. Suicide prevention strategies: a systematic review. JAMA. Oct
26; 2005 294(16):2064–2074. [PubMed: 16249421]
73. LeFevre ML, Force USPST. Screening for suicide risk in adolescents, adults, and older adults in
Author Manuscript
primary care: U.S. Preventive Services Task Force recommendation statement. Ann Intern Med.
May 20; 2014 160(10):719–726. [PubMed: 24842417]
74. Jena AB, Prasad V. Primary care physicians’ role in counseling about gun safety. Am Fam
Physician. Nov; 2014 90(9):619–620. [PubMed: 25368919]
75. Wasserman D, Varnik A. Suicide-preventive effects of perestroika in the former USSR: the role of
alcohol restriction. Acta Psychiatr Scand Suppl. 1998; 394:1–4. [PubMed: 9825011]
76. Almeida OP, Pirkis J, Kerse N, et al. A randomized trial to reduce the prevalence of depression and
self-harm behavior in older primary care patients. Ann Fam Med 2012. Jul-Aug;2012 10(4):347–
356.
77. Lai MH, Maniam T, Chan LF, Ravindran AV. Caught in the web: a review of web-based suicide
prevention. J Med Internet Res. 2014; 16(1):e30. [PubMed: 24472876]
78. Watts S, Newby JM, Mewton L, Andrews G. A clinical audit of changes in suicide ideas with
internet treatment for depression. BMJ Open. 2012; 2(5)
79. Tarrier N, Taylor K, Gooding P. Cognitive-behavioral interventions to reduce suicide behavior: a
systematic review and meta-analysis. Behav Modif. Jan; 2008 32(1):77–108. [PubMed: 18096973]
Author Manuscript
80. Linehan MM, Comtois KA, Murray AM, et al. Two-year randomized controlled trial and follow-up
of dialectical behavior therapy vs therapy by experts for suicidal behaviors and borderline
personality disorder. Arch Gen Psychiatry. Jul; 2006 63(7):757–766. [PubMed: 16818865]
81. Simon GE, Savarino J. Suicide attempts among patients starting depression treatment with
medications or psychotherapy. Am J Psychiatry. Jul; 2007 164(7):1029–1034. [PubMed:
17606654]
82. While D, Bickley H, Roscoe A, et al. Implementation of mental health service recommendations in
England and Wales and suicide rates, 1997–2006: a cross-sectional and before-and-after
observational study. Lancet. Mar 17; 2012 379(9820):1005–1012. [PubMed: 22305767]
Med Clin North Am. Author manuscript; available in PMC 2018 May 01.
Weber et al. Page 16
83. Carter G, Reith DM, Whyte IM, McPherson M. Repeated self-poisoning: increasing severity of
self-harm as a predictor of subsequent suicide. Br J Psychiatry. Mar.2005 186:253–257. [PubMed:
Author Manuscript
15738507]
84. Joiner T, Kalafat J, Draper J, et al. Establishing standards for the assessment of suicide risk among
callers to the national suicide prevention lifeline. Suicide Life Threat Behav. Jun; 2007 37(3):353–
365. [PubMed: 17579546]
85. Excellence NIfHaC. , editor. NICE. Depression in adults: Reognition and Management. 2009.
86. Bronheim HE, Fulop G, Kunkel EJ, et al. The Academy of Psychosomatic Medicine practice
guidelines for psychiatric consultation in the general medical setting. The Academy of
Psychosomatic Medicine. Psychosomatics. Jul-Aug;1998 39(4):S8–30. [PubMed: 9691717]
87. Unützer J, Tang L, Oishi S, et al. Reducing suicidal ideation in depressed older primary care
patients. J Am Geriatr Soc. Oct; 2006 54(10):1550–1556. [PubMed: 17038073]
88. Griffiths JJ, Zarate CA Jr, Rasimas JJ. Existing and novel biological therapeutics in suicide
prevention. Am J Prev Med. Sep; 2014 47(3 Suppl 2):S195–203. [PubMed: 25145739]
89. Bridge JA, Iyengar S, Salary CB, et al. Clinical response and risk for reported suicidal ideation and
suicide attempts in pediatric antidepressant treatment: a meta-analysis of randomized controlled
Author Manuscript
bipolar and unipolar disorders. The Journal of clinical psychiatry. Jul; 2014 75(7):720–727.
[PubMed: 25093469]
96. Gibbons RD, Brown CH, Hur K, Davis J, Mann JJ. Suicidal thoughts and behavior with
antidepressant treatment: reanalysis of the randomized placebo-controlled studies of fluoxetine and
venlafaxine. Archives of general psychiatry. Jun; 2012 69(6):580–587. [PubMed: 22309973]
97. Zalsman G, Hawton K, Wasserman D, et al. Suicide prevention strategies revisited: 10-year
systematic review. The lancet. Psychiatry. Jul; 2016 3(7):646–659. [PubMed: 27289303]
98. Valuck RJ, Libby AM, Orton HD, Morrato EH, Allen R, Baldessarini RJ. Spillover effects on
treatment of adult depression in primary care after FDA advisory on risk of pediatric suicidality
with SSRIs. Am J Psychiatry. Aug; 2007 164(8):1198–1205. [PubMed: 17671282]
99. Carlsten A, Waern M. Are sedatives and hypnotics associated with increased suicide risk of suicide
in the elderly? BMC Geriatr. 2009; 9:20. [PubMed: 19497093]
100. Didham R, Dovey S, Reith D. Characteristics of general practitioner consultations prior to
suicide: a nested case-control study in New Zealand. N Z Med J. 2006; 119(1247):U2358.
[PubMed: 17195851]
Author Manuscript
101. Hughes DH. Can the clinician predict suicide? Psychiatric services. May; 1995 46(5):449–451.
[PubMed: 7627668]
102. Simon R, Shuman DW. The standard of care in suicide risk assessment: An elusive concept. CNS
spectrums. Jun; 2006 11(6):442–445. [PubMed: 16816783]
103. Bryan CJ, Corso KA, Corso ML, Kanzler KE, Ray-Sannerud B, Morrow CE. Therapeutic alliance
and change in suicidal ideation during treatment in integrated primary care settings. Arch Suicide
Res. 2012; 16(4):316–323. [PubMed: 23137221]
Med Clin North Am. Author manuscript; available in PMC 2018 May 01.
Weber et al. Page 17
104. Schulberg HC, Block MR, Madonia MJ, et al. Treating major depression in primary care practice.
Eight-month clinical outcomes. Arch Gen Psychiatry. Oct; 1996 53(10):913–919. [PubMed:
Author Manuscript
8857868]
105. Graham RD, Rudd MD, Bryan CJ. Primary care providers’ views regarding assessing and treating
suicidal patients. Suicide Life Threat Behav. Dec; 2011 41(6):614–623. [PubMed: 22145822]
Author Manuscript
Author Manuscript
Author Manuscript
Med Clin North Am. Author manuscript; available in PMC 2018 May 01.
Weber et al. Page 18
KEY POINTS
Author Manuscript
1. Screening tools, including but not limited to the Patient Health Questionnaire
-9 (PHQ-9) and the Columbia Suicide Severity Rating Scale (C-SSRS) may
identify individuals at risk and in need of further assessment.
3. There exist a variety of interventions for which to target risk of suicide that
may be tailored to the individuals risk profile.
Author Manuscript
Author Manuscript
Author Manuscript
Med Clin North Am. Author manuscript; available in PMC 2018 May 01.
Weber et al. Page 19
Box 1
Author Manuscript
The patient is a 67 year-old married, retired male construction worker who with ischemic cardiomyopathy and
recent increased use of alcohol, placing him at a moderate to high risk of suicide. He has no history of suicide
attempts and a strong support system. He had a recent hospitalization for a myocardial infarction, during which
he developed a depressive syndrome and he appears increasingly hopeless about the future, particularly
surrounding his medical bills and debt. While intoxicated last week, he reported having vague and fleeting
suicidal thoughts though denies any past or current intent of acting on these thoughts. His wife is not aware of
any acute evidence of dangerousness and was willing to secure the patients firearms and excess medications. He
was offered hospitalization, but declined. There is insufficient evidence of acute dangerousness to warrant
involuntary hospitalization. Patient agrees to quit drinking and engage in close follow-up for his depression with
referral to a psychiatrist. He verbalizes intent to seek emergent assistance if feeling unsafe.
Author Manuscript
Author Manuscript
Author Manuscript
Med Clin North Am. Author manuscript; available in PMC 2018 May 01.
Weber et al. Page 20
Table 1
Many young people at your age are starting to experiment with cigarettes or alcohol. Have you tried these or other
Drugs drugs like marijuana, injection drugs, or other substances?
How much are you taking and how often?
What sort of things do you do if you are feeling sad, angry, or hurt?
Author Manuscript
Some people who feel really down often feel like hurting themselves or even killing themselves. Have you ever felt
Suicide/safety this way?
Have you ever tried to hurt yourself?
Do you have access to firearms in your home or the home of a friend or family member?
Author Manuscript
Author Manuscript
Med Clin North Am. Author manuscript; available in PMC 2018 May 01.
Weber et al. Page 21
Table 2
Name Source(s)
Practice Parameter for Assessment and Treatment of Children and Adolescents with American Academy of Child and Adolescent
Suicidal Behaviors Psychiatry
Practice Guideline for the Assessment and Treatment of Patients with Suicidal Behaviors American Psychiatric Association (APA)
VADOD Clinical Practice Guidelines for Assessment and Management of Patients at Department of Veterans Affairs, Department of
Risk for Suicide Defense
Assessment and Care of Adults at Risk for Suicidal Ideation and Behavior Registered Nurses’ Association of Ontario
Core Competencies for Assessment and Management of Suicide American Association of Suicidology
National Suicide Prevention Lifeline Suicide Risk Assessment Standards Packet National Suicide Prevention Lifeline, SAMSHA
Suicide Assessment Five-step Evaluation and Triage (SAFE-T) SAMSHA
Suicide Prevention: Saving Lives One Community at a Time American Foundation for Suicide Prevention
(AFSP)
Author Manuscript
Med Clin North Am. Author manuscript; available in PMC 2018 May 01.
Weber et al. Page 22
Table 3
Chronic Acute
Med Clin North Am. Author manuscript; available in PMC 2018 May 01.
Weber et al. Page 23
Table 4
Med Clin North Am. Author manuscript; available in PMC 2018 May 01.
Weber et al. Page 24
Table 5
Characteristics of Level
Acute Risk Level Recommended Response
Protective Factors Acute Risk Factors Suicidal Evaluation
1 Increase frequency/
duration of visits. Repeated
evaluation of need for
hospitalization.
2 Involve family and support
Author Manuscript
system.
3 Means restriction.
4 Review emergency
protocols, such as
Baseline chronic risk Frequent suicidal emergency rooms and
factors. Minimal mood ideation, still limited in crisis services.
Some identifiable
Moderate symptoms. Maintained intensity and duration.
protective factors. 5 Control mood symptoms
self-control. Rare acute May have plan, but no
risk factors. intent. with medications and/or
psychotherapy.
6 Frequent follow-up with
phone calls or nursing
visits (if available).
7 Consider psychiatric
referral and/or
hospitalization, especially
if risk increasing with re-
evaluation.
Author Manuscript
Med Clin North Am. Author manuscript; available in PMC 2018 May 01.