Lo Week 5 (2) 1. Classification of MSK Infection

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LO WEEK 5 (2)

1. Classification of MSK infection


 Duration (acute- subacute- chronic) and mechanism (haematogenous
contagious focus of infection) Lewand Waldvogel
 Affected portion of bone, Host status and local environment (stage 1
medullary, 2 superficial,3 localized, 4 diffuse) Cierny and mader

Other types of bone infections


a. Garre Sclerosing Osteomyelitis
 Garré, in 1893, described a rare form of non- suppurative osteomyelitis
which is characterized by marked sclerosis and cortical thickening.
 There is no abscess, only a diffuse enlargement of the bone at the
affected site – usually the diaphysis of one of the tubu- lar bones or the
mandible.
b. Multifocal non-suppurative osteomyelitis
 1) it is not as rare as initially suggested; (2) it comprises several different
syndromes which have certain fea- tures in common; and (3) there is an
association with chronic skin infection, especially pustular lesions of the
palms and soles (palmo-plantar pustulosis) and pustular psoriasis.
c. Infantile Cortical Hyperostosis (Caffey’s Disease)
Infantile cortical hyperostosis is a rare disease of infants and young children. It
usually starts during the first few months of life with painful swelling over the
tubular bones and/or the mandible. The child may be feverish and irritable,
refusing to move the affected limb. Infection may be suspected but, apart from
the swelling, there are no local signs of inflammation. The ESR, though, is usually
elevated.

d. Acute suppurative arthritis


(1) direct invasion through a penetrating wound, intra-articular injection or
arthroscopy; (2) direct spread from an adjacent bone abscess; or (3) blood
spread from a distant site. In infants it is often difficult to tell whether the infec-
tion started in the metaphyseal bone and spread to the joint or vice versa.

2. How is the drainage of the sinus is done


 Local spread of the infection within the medullary cavity further
compromises the internal circulation
 The resultant area of bone necrosis eventually becomes separated from
the living bone, therefore forming sequestra.
 Bacteria are able to survive and continue multiply within the tiny haversian
canals and canaliculi of this island of avascular bone
 The surrounding pond of pus prevents revascularization of the
sequestrum and thereby protects its bacterial inhabitants not only from the
living leucocytes but also from the action of circulating antibiotics
 Extensive new bone formation from the deep layer of elevated periosteum
produces an enveloping bony tube (involcrum), which maintains the
continuity of the involved bone
 To remove the sequestra, there is natural process of spontaneous
extrustion through an opening in the involcrum and hence through a sinus
tract to the exterior.
 This leads to chronic phase of the disease

3. Saucerization and muscle flap transfer
4. How is IV done in osteomyelitis

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