Problem Set Patterns of Inheritance

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HOLY SPIRIT ACADEMY OF MALOLOS

Bagong Bayan, City of Malolos


SY 2018-2019
Biology 2
Problem Set - Patterns of Inheritance

Name___________________________________Grade and Section __________ Date______Score ________

Instructions: Answer all the questions, explaining all your answers and showing your Punnett squares or
pedigree charts whenever applicable

1. 8 points

A. Is the trait dominant or recessive?

B. What are the most probable genotypes of I-2 and I-3?


C. What is the probability that II-2 is Dd?

D. What is the probability that II-1 and II-2 will have another normal offspring?

2. (10 points) The last Emperor of Russia, Nicolas II, was married to Empress Alexandra, and they had five
children, Olga, Tatiana, Maria, Anastasia, and Alexis. Alexis was the only one who was afflicted with
hemophilia or the royal bleeding disease; all other members were normal.

0 Draw the pedigree diagram

0 Research on this medical condition and determine the mode of inheritance.

0 If only Prince Alexis was afflicted with the disease, determine his genotype.

0 What could be the genotypes of the Emperor and Empress?


0 Is it possible that each daughter could have been a carrier?

3. (10 points) In cattle, coat color is inherited in a co-dominant fashion. Homozygous B1B1 produces black
coat, homozygous B2B2 produces white coat, and the heterozygous B1B2 produces roan coat. Give the
genotypic and phenotypic ratios of the offspring of the following crosses:

A.
B1B1x B1B1

B.
B1B1x B2B2

C.
B1B2x B1B2

D. B1B1x B1B2
E.
B1B2x B2B2

4. (6 points) In guinea pigs, coat color is governed by four alleles that constitute a multiple allelic series, C
(black), cS (sepia), cC (cream), and c (albino) with the following dominance hierarchy: C>cS>cC>c. Determine
the genotypic and phenotypic ratios of the progeny from the following crosses:

A. Cc x CcS

B. CcS x cCc

5. (10 points) A local hospital has sent word to a family of a possible mix up of some of the children with
other families when they were born. To rule out any possible mix up, the hospital obtained the blood types
of every individual in the family, including the surviving maternal grandfather and paternal grandmother.
The results were as follows:

Father: Type O

Mother: Type A
1st child: Type O
2nd child: Type A
3rd child: Type B

Maternal grandfather: Type AB

Paternal grandmother: Type B

Based on the results, is there a possibility that any one of the children is not a biological offspring of the

couple?

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