MULTIPLE CHOICE QUESTIONS (PHARMACEUTICS)

!!JAY AMBE!!

MULTIPLE CHOICE QUESTIONS

(PHARMACEUTICS)

I
ED
PREPARED BY

IV
DR. NAITIK D. TRIVEDI,
M. PHARM, PH. D
TR

I
&
LECTURER AT GOVERNMENT AIDED,

ED
A. R. COLLEGE OF PHARMACY & G. H. PATEL INSTITUTE OF
D

IV
PHARMACY, VALLABH VIDYANAGAR, ANAND.
IK

Mobile: +91 - 9924567864

TR
E-mail: mastermindnaitik@gmail.com
IT

N.
NA

&
A
.

DR. UPAMA N. TRIVEDI,

AM
DR

M. PHARM, PH. D
UP

ASSOCIATE PROFESSOR & HoD (Pharm.D),

INDUBHAI PATEL COLLEGE OF PHARMACY AND RESEARCH
.

CENTRE, DHARMAJ.
DR

E-mail: ups.aasthu@gmail.com

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 MULTIPLE CHOICE QUESTIONS (PHARMACEUTICS)

PHARMACEUTICS (MCQ)

1. Which of the following gelatine concentration is used to determine the viscosity of gelatine used
for the preparation of soft gelatine capsules?
A. 6 2/3 %
B. 7 2/3%
C. 5 2/3 %
D. 6 3/4%

I
Ans. A

ED
2. Department of Transport Test (DOT) is performed for which of the following?
A. Aerosols

IV
B. Glass containers
C. Capsules TR
D. None

I
&
Ans. A

ED
3. Measurement of particle size in pharmaceutical aerosol is by
D

(P) Cascade impactor (Q) Light scatter decay (R) K-F method (S) IR

IV
A. Q, R
B. R, S
IK

C. P, S

TR
D. P, Q
IT

Ans. D
N.
4. According to Drugs and Cosmetics act, List of substances that should be sold by retail only on
NA

prescription of registered medical practitioner is given in which of the following Schedule?

A. Schedule 'H'
B. Schedule 'V'
A

C. Schedule 'X'
.

D. Schedule 'Q'
AM
DR

Ans. A
UP

5. Identify the correct non-flammable propellant

A. Dichloro monofluoro methane
B. Trichloro monofluoro methane
C. Di methyl ether
.

D. Di fluoro methane
DR

Ans. B

6. The first aerosol insecticide was developed by

A. Good-hue & Sullivan
B. Good-hue
C. Sullivan
D. Franklin
Ans. A

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 MULTIPLE CHOICE QUESTIONS (PHARMACEUTICS)

7. The first pharmaceutical aerosol was developed in the year of

A. 1945
B. 1955
C. 1949
D. 1960
Ans. B

I
8. Which drug is formulated as first pharmaceutical aerosol?

ED
A. Epinephrine
B. Codeine
C. Chloropromazine

IV
D. Probenecid
Ans. A TR

I
&
9. The dip tube in an aerosol container is made from one of the following

ED
A. Poly propylene
B. Glass
D

C. Al

IV
D. Stainless steel
Ans. A
IK

TR
10. Which one of the following device is used to increase the efficiency of drug delivery via aerosols?
IT

A. Tube spacers
B. Metered valves
N.
C. Actuator
NA

D. Pressure valve
Ans. B
A

11. To dispense inhalation aerosols, which containers are used?

.

A. Stain less steel containers

AM
DR

B. Tin plate containers

C. Glass containers
UP

D. Al containers
Ans. A

12. The valve body /housing in a aerosol bottle valve assembly, is made from one of the following
.

A. Poly propylene
DR

B. Poly ethylene
C. Nylon
D. Stain less steel
Ans. C

13. Among the propellants used in aerosols, one of the following is used for topical pharmaceutical aerosols
A. Tri chloro monofluoro methane
B. Di chloro difluoro methane

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 MULTIPLE CHOICE QUESTIONS (PHARMACEUTICS)

C. Di chloro tetrafluoro ethane

D. Propane
Ans. D

14. Which one of the following propellant is used in the aerosol for oral use
A. Propane
B. Oxygen
C. Trichloro monofluoro methane

I
D. Methane

ED
Ans. C

15. The identification of propellants in pharmaceutical aerosols is carried out by

IV
(P) Gas chromatography (R) Pycnometer (Q) Tag open cup apparatus (S) IR spectrophotometer
A. P,Q TR
B. P,S

I
&
C. Q, R

ED
D. R, S
Ans. B
D

IV
16. Aerosol packaging container mustresist pressure of
A. 500 psig
IK

B. 140-180 psig

TR
C. 40 psig
IT

D. 20 psig
Ans. B
N.
NA

17. Gasket is made up of

A. Bure-N
B. Neoprene rubber
A

C. Both
.

D. Non of above
AM
DR

Ans. C
UP

18. Manufacturing of aerosol involves

A. Gas filling
B. Pressure filling
C. Compressed gas filling
.

D. All the above

DR

Ans. C

19. The nature of propellant is determined by

A. R-F method
B. Gas Chromatography
C. UVD.
D. None
Ans. B

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 MULTIPLE CHOICE QUESTIONS (PHARMACEUTICS)

20. Viscosity enhancer in ophthalmic preparation is

A. Poly vinyl alcohol
B. Povidone
C. Dextran
D. Macrogol
Ans. D

I
ED
21. Ph of human tear is
A. 7.6
B. 4.5

IV
C. 7.2
D. 9 TR
Ans. A

I
&

ED
22. Opthalmic solution is sterilized by
A. Autoclave
D

B. Hot air oven

IV
C. Membrane filter
D. Bacterial filters
IK

Ans. A

TR
IT

23. Which of the following one is used to adjust the isotonicity

A. Dextrose
N.
B. Boric acid
NA

C. NaCl
D. All the above
Ans. D
A
.

24. The ability of a substance dissolves in a given solvent system is depends on

AM
DR

A. Nature and intensity of the forces present in the solute

B. Nature and intensity of the forces present in the solvent
UP

C. Interactions between solute and solvent

D. All the above
Ans. A
.

25. Which of the following substances having poor water solubility

DR

A. Weak electrolytes
B. Non-polar molecules
C. Both
D. None
Ans. C

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 MULTIPLE CHOICE QUESTIONS (PHARMACEUTICS)

26. How co-solvents increase the solubility of poorly soluble drugs?

A. By reducing the interfacial tension between the predominant aqueous solution and
hydro- phobic solute
B. By reducing the interfacial tension between solute and solvent
C. Both
D. None
Ans. A

I
27. The solubility of weak electrolytes &non-polar substances can be increased by

ED
adding water miscible solvents. This process is known as
A. Co-solvency
B. Complexation

IV
C. Both
D. None TR
Ans. A

I
&
28. Which of the following co – solvents are used to increase the solubility of a drug

ED
A. Ethanol
D

B. Sorbitol

IV
C. Glycerin
D. All the above
IK

Ans. D

TR
IT

29. Which of the following co – solvent is accepted as a co – solvent in

parenteral products, but its use in oral liquids is limited
N.
A. Glycerol formal
NA

B. Glycerol
C. Dimethyl acetamide
D. None
A

Ans. C
.

AM
DR

30. Due to which factor, dimethyl aceta-mide is not been used as a co-solvent in oral liquids
A. Due to objectionable odor
UP

B. Due to objectionable taste

C. Both
D. None
Ans. C
.
DR

31. Thiomersal is belongs to which category preservative

A. Acidic
B. Mercurial
C. Neutral
D. Quaternary ammonium compounds
Ans. B

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 MULTIPLE CHOICE QUESTIONS (PHARMACEUTICS)

32. Which of the following are widely used and excellent preservatives
A. Quaternary ammonium compounds
B. Mercurial
C. Both
D. Acidic
Ans. A

33. Benzalkonium chloride is categorized as

I
A. Acidic preservative

ED
B. Neutral preservative
C. Mercurial preservative
D. Quaternary ammonium compounds

IV
Ans. D
TR
34. At which concentration, phenol act as preservative

I
A. 0.2 – 0.5

&
B. 0.5 – 0.8

ED
C. 0.05 – 0.1
D

D. None

IV
Ans. A
IK

35. Which of the following sugar has bitter taste

TR
A. Glucose
IT

B. Sucrose
C. Saccharine
N.
D. None
NA

Ans. C

36. Which of the following is a synthetic sweetener

A

A. Glucose
.

B. Sucrose
AM
DR

C. Sorbitol
D. Aspartame
UP

Ans. D

37. To increase the viscosity of liquid, which of the following agents are used
A. PVP
.

B. Methyl Cellulose
DR

C. Sodium Carboxy Methyl Cellulose

D. All the above
Ans. D

38. Which of the following agents are used as flavoring agents

A. Menthol
B. Chloroform
C. Both

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 MULTIPLE CHOICE QUESTIONS (PHARMACEUTICS)

D. None
Ans. C

39. Most widely used flavoring agent in food industry

A. Menthol
B. Chloroform
C. Mono sodium glutamate
D. None

I
Ans. C

ED
40. Which of the following flavor is not responsible for sour taste
A. Citrus flavors

IV
B. Liquorice
C. Raspberry TR
D. Mint spice

I
&
Ans. D

ED
41. The filling method of a pharmaceutical liquid depends on the following factors
D

A. Viscosity of the liquid

IV
B. Surface tension of the liquid
C. Compatibility with the materials used in the construction of the filling machine D. All the above
IK

Ans. D

TR
IT

42. Which of the following methods are generally used in liquid filling
A. Gravimetric
N.
B. Volumetric
NA

C. Constant level method

D. All the above
Ans. D
A
.

43. In the formulation of suspensions, generally which types of drugs areselected?

AM
DR

A. Hydrophilic
B. Hydrophobic
UP

C. Both
D. None
Ans. B
.

44. In the formulation, to facilitate the wetting of insoluble solids, which of the following agents
DR

used
A. Suspending agents
B. Wetting agents
C. Flavoring agents
D. None
Ans. B

45. How surfactants will facilitate or aid wetting of hydrophobic materials in liquid

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 MULTIPLE CHOICE QUESTIONS (PHARMACEUTICS)

A. By decreasing the solid-liquid interfacial tension

B. By increasing the solid-liquid interfacial tension
C. Both
D. None
Ans. A

46. The stability of suspensions can be evaluated by

A. Sedimentation volume

I
B. Degree of flocculation

ED
C. Re-dispersibility
D. All
Ans. D

IV
47. To identify the emulsion type, which of the following tests are conducted?
TR
A. Dilution test

I
&
B. Dye test

ED
C. Conductivity test
D. All
D

Ans. D

IV
48. Stoke’s equation is expressed as
IK

A. V = 2r2(d1–d2)g/18η

TR
B. V = 2r2(d1–d2)g/9η
IT

C. Both
D. None
N.
Ans. B
NA

49. The temperature at which the inversion occurs depends on emulsifier concentration is known
as
A

A. Phage temperature
.

B. Inversion temperature
AM
DR

C. Phase inversion temperature

D. All
UP

Ans. D

50. Which of the following mechanical equipment can be used for emulsification?
A. Homogenizers
.

B. Mechanical stirrers
DR

C. Ultrasonifiers
D. All
Ans. D

51. Which of the following is not used as a emulsifying agent?

A. Surfactant
B. Hydrophilic colloids
C. Electrolytes

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 MULTIPLE CHOICE QUESTIONS (PHARMACEUTICS)

D. Finely divided solids

Ans. C

52. HLB system was developed by

A. Griffin
B. Stock’s
C. Dalla Valle
D. None

I
Ans. A

ED
53. Gum Arabic is a
A. Anionic polysaccharide

IV
B. Cationic polysaccharide
C. Neutral polysaccharide TR
D. None

I
&
Ans. C

ED
54. Which of the following is not a semisolid dosage form
D

A. Paste

IV
B. Creams
C. Ointments
IK

D. Suspensions

TR
Ans. D
IT

55. Generally pastes contain

N.
A. High percentage of insoluble solids
NA

B. Low percentage of insoluble solids

C. Both
D. None
A

Ans. A
.

AM
DR

56. Most widely used hydrocarbon in semisolid dosage forms

A. Petrolatum
UP

B. Mineral oil
C. Both
D. None
Ans. C
.
DR

57. Which of the following hydrocarbon waxes are employed in the manufacture of creams and
ointments?
A. Paraffin wax
B. Ceresin
C. Both
D. None
Ans. C

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 MULTIPLE CHOICE QUESTIONS (PHARMACEUTICS)

58. Which of the following is not a vegetable oil

A. Peanut oil
B. Almond oil
C. Olive oil
D. Petrolatum
Ans. D

59. Which of the following fatty acid used in water removable creams as emulsifier?

I
A. Palmitic acid

ED
B. Stearic acid
C. Both
D. None

IV
Ans. B
TR
60. Combination of a surfactant with oil-soluble auxiliary emulsifier is known as

I
&
A. Simple emulsifier system

ED
B. Mixed emulsifier system
C. Both
D

D. None

IV
Ans. B
IK

61. Promulgen means

TR
A. Anionic emulsifiers composed of fatty alcohols & their ethoxylates
IT

B. Non-ionic emulsifiers composed of fatty alcohols & theirethoxylates

C. Cationic emulsifiers composed of fatty alcohols & their ethoxylates
N.
D. All the above
NA

Ans. B

62. Promulgen D contains

A

A. Cetyl alcohol & Ceteareth-20

.

B. Stearyl alcohol & Ceteareth-20

AM
DR

C. Both
D. None
UP

Ans. A

63. Promulgen G contains

A. Cetyl alcohol & Ceteareth-20
.

B. Stearyl alcohol & Ceteareth-20

DR

C. Both
D. None
Ans. B

64. With promulgen D, which type of emulsion generally obtained?

A. Liquid emulsion
B. Thick consistency emulsion
C. Both

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 MULTIPLE CHOICE QUESTIONS (PHARMACEUTICS)

D. None
Ans. B

65. With promulgen G, which type of emulsion generally obtained?

A. Liquid emulsion
B. Thick consistency emulsion
C. Both
D. None

I
Ans. A

ED
66. Which of the following polyols used as humectants in creams
A. Glycerine

IV
B. Propylene glycol
C. Sorbitol 70% TR
D. All the above

I
&
Ans. D

ED
67. The choice of humectants is based on
D

A. Rate of moisture exchange

IV
B. Viscosity and texture of preparation
C. Both
IK

D. None

TR
Ans. C
IT

68. Which of the following is more hygroscopic at low concentration?

N.
A. Sorbitol 70%
NA

B. Glycerine
C. Both
D. None
A

Ans. A
.

AM
DR

69. Water number means

A. Maximum amount of water that can be added to 100 g of a base at given temperature
UP

B. Maximum amount of water that can be added to 10 g of a base at given temperature

C. Maximum amount of water tha tcan be added to 5 g of a base at given temperature
D. All
Ans. A
.
DR

70. Lanolin is which type of base

A. Hydrocarbon base
B. Absorption base
C. None
D. Both
Ans. D

71. In the preparation of vanishing creams, which types of bases are used generally?

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 MULTIPLE CHOICE QUESTIONS (PHARMACEUTICS)

A. Absorption bases
B. Water removable bases
C. Hydrocarbon bases
D. None
Ans. B

72. In the preparation of cold creams, which types of bases are used generally?
A. Absorption bases

I
B. Water removable bases

ED
C. Hydrocarbon bases
D. None
Ans. A

IV
73. Water soluble bases are also known as
TR
A. Greasy ointment bases

I
&
B. Greaseless ointment bases

ED
C. Both
D. None
D

Ans. B

IV
74. In pastes, the concentration of insoluble powder substances in
IK

A. 20%-50%

TR
B. 50%-100%
IT

C. 50%-75%
D. None
N.
Ans. A
NA

75. Jellies are generally

A. Water-soluble bases
A

B. Water-insoluble bases
.

C. Both
AM
DR

D. None
Ans. A
UP

76. As per USP XX, the term “object ionable” means

A. An organism can cause disease or the presence may interrupt the function of the drug or lead to
deterioration of the product
.

B. Pathogens if they produce disease or infection, in the newborn or debilitated persons

DR

C. Organisms or their toxins that are responsible for human disease or infection
D. None
Ans. A

77. A suppository is generally intended for use in

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 MULTIPLE CHOICE QUESTIONS (PHARMACEUTICS)

A. Rectum
B. Vagina
C. Urethra
D. All the above
Ans. D

78. Vaginal suppositories also called as

A. Pessaries

I
B. Simple suppositories

ED
C. Bougies
D. None
Ans. A

IV
79. “Oleum theobromae” was first recom-mended by
TR
A. A. B. Taylor

I
&
B. Griffin
C. Stocks’s

ED
D. None
D

Ans. A

IV
80. Weight of rectal suppository for adults is
IK

A. 1 g

TR
B. 2 g
IT

C. 5 g
D. None
N.
Ans. B
NA

81. Weight of rectal suppository for children is

A. 1 g
A

B. 2 g
.

C. 5 g
AM
DR

D. None
Ans. A
UP

82. Urethral suppositories also called as

A. Pessaries
B. Bougies
.

C. Both
DR

D. None
Ans. B

83. Urethral suppositories having which shape

A. Oviform shape
B. Torpedo shape
C. Pencil shape
D. None

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 MULTIPLE CHOICE QUESTIONS (PHARMACEUTICS)

Ans. C

84. Weight of urethral suppository for males & females respectively

A. 4 & 2
B. 2 & 4
C. 4 & 6
D. 6 & 4
Ans. A

I
ED
85. Shape of vaginal suppositories is
A. Oviform shape
B. Torpedo shape

IV
C. Pencil shape
D. None TR
Ans. A

I
&

ED
86. Rectal suppositories mainly used for the treatment of
A. Constipation
D

B. Hemorrhoids

IV
C. Both
D. None
IK

Ans. C

TR
IT

87. The number of milligrams of KOH required neutralizing free acids & saponify the esters
contained in 1 g of fat is known as
N.
A. Iodine value
NA

B. Saponification value
C. Water number
D. Acid value
A

Ans. B
.

AM
DR

88. The number of grams of iodine that reacts with 100 g of fat is known as
A. Iodine value
UP

B. Saponification value
C. Water number
D. Acid value
Ans. A
.
DR

89. The number of milligrams of KOH required neutralizing free acids in 1g of fat is known as
A. Iodine value
B. Saponification value
C. Hydroxil value
D. Acid value
Ans. D

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 MULTIPLE CHOICE QUESTIONS (PHARMACEUTICS)

90. The number of milligrams of KOH required neutralize the acetic acid used to acetylate 1 g of
fat is known as
A. Iodine value
B. Saponification value
C. Hydroxil value
D. Acid value
Ans. C

I
91. Which of the following method is used to manufacture suppositories

ED
A. Hand molding
B. Compression molding
C. Pour molding

IV
D. All the above
Ans. D TR

I
&
92. Which of the following is most commonly used suppository base

ED
A. Cocoa butter
B. PEG 1000
D

C. PEG + Hexanetriol

IV
D. None
Ans. A
IK

TR
93. Cocoa butter available in following forms
IT

A. α-form
B. β-form
C. γ-form
N.
NA

D. All
Ans. D
A

94. The solidification point of cocoa butterlies between

.

A. 12 – 13oC
AM
DR

B. 20 – 30oC
C. 5 – 10oC
UP

D. None
Ans. A

95. Which of the following method is simple & oldest method of preparation of suppositories?
.

A. Pour molding
DR

B. Hand molding
C. Compression molding
D. All the above
Ans. B

96. Most commonly used method for producing suppositories on both a small & large scale is
A. Hand molding
B. Compression molding

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 MULTIPLE CHOICE QUESTIONS (PHARMACEUTICS)

C. Pour molding
D. All the above
Ans. C

97. Which formula can be used to calculate the amount of base that is replaced by active
ingredients?
A.100 (G–E)f=+1(G) (X)
B.100 (E–G)f=+100(G) (X)

I
C. 100 (E–G)f=+1(G) (X)

ED
D.100 (E–G)f=+10(G) (X)
Ans. C

IV
98. Rancidity generally results from
A. Auto oxidation TR
B. Decomposition of unsaturated fats

I
&
C. Both

ED
D. None
Ans. C
D

IV
99. Which of the following is not antioxi-dant
A. BHT
IK

B. BHA

TR
C. Tocopherol
IT

D. Theobroma oil
Ans. D
N.
NA

100. Suppositories are generally evaluated by

A. Melting range test
B. Breaking test
A

C. Liquefaction
.

D. All the above

AM
DR

Ans. D
UP

101. Which of the following materials are used in pharmaceutical packaging?

A. Glass
B. Plastic
C. Metal
.

D. All the above

DR

Ans. D

102. Which of the following packaging material is protect the drug content against light
A. Plastic containers
B. Amber colored glass containers
C. Both
D. None
Ans. B

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 MULTIPLE CHOICE QUESTIONS (PHARMACEUTICS)

103. Major disadvantages of glass as a packing material are

A. Fragility
B. Weight
C. Both
D. None
Ans. C

I
104. Composition of glass is

ED
A. Sand
B. Soda ash
C. Lime stone & Cullet

IV
D. All the above
Ans. D TR

I
&
105. Soda ash also known as

ED
A. Pure silica
B. Sodium carbonate
D

C. Lime stone

IV
D. Calcium carbonate
Ans. B
IK

TR
106. Which of the following one is a broken glass & acts as fusion agent
IT

A. Cullet
B. Soda ash
N.
C. Lime stone
NA

D. Sand
Ans. A
A

107. Which of the following methods are used in the production of glass
.

A. Blowing
AM
DR

B. Drawing
C. Pressing & casting
UP

D. All the above

Ans. D

108. To produce molten glass, which of the following method is used

.

A. Blowing
DR

B. Drawing
C. Pressing
D. Casting
Ans. A

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 MULTIPLE CHOICE QUESTIONS (PHARMACEUTICS)

109. To protect the contents of a bottle from the effects of sunlight by UV rays, which glass is
used?
A. Amber glass
B. Red glass
C. Both
D. None
Ans. C

I
110. To evaluate the chemical resistance of glass, which of the following tests areconducted?

ED
A. Powder glass
B. Water attack test
C. Both

IV
D. None
Ans. C TR

I
&
111. Which of the following test is performed on crushed grains, to evaluate the chemical

ED
resistance of glass?
A. Powder glass
D

B. Water attack test

IV
C. Both
D. None
IK

Ans. A

TR
IT

112. Which of the following test is performed on whole container?

A. Powder glass
N.
B. Water attack test
NA

C. Both
D. None
Ans. B
A
.

113. Type I glass is also known as

AM
DR

A. Borosilicate glass
B. Regular soda-lime glass
UP

C. Treated soda-lime glass

D. None
Ans. A
.

114. The advantages of plastic containers over glass containers are

DR

A. Easy formation
B. Resistance to breakage
C. Freedom of design
D. All the above
Ans. D

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 MULTIPLE CHOICE QUESTIONS (PHARMACEUTICS)

115. Plastic containers are generally made from the following material
A. Polyethylene
B. Polypropylene
C. Polystyrene
D. All the above
Ans. D

116. Which of the following ingredients are present in rubber stopper?

I
A. Vulcanizing agent

ED
B. Softner
C. Antioxidant
D. All the above

IV
Ans. D
TR
117. Which of the following packaging systems are identified by the FDA?

I
&
A. Blister pack

ED
B. Strip pack
C. Bubble pack
D

D. All the above

IV
Ans. D
IK

118. Which of the following packaging is commonly used for packaging of tablets & capsules?

TR
A. Blister pack
IT

B. Strip pack
C. Both
N.
D. None
NA

Ans. B

119. Which of the following materials offer moisture barrier properties?

A

A. Aclar
.

B. Cellophane
AM
DR

C. Polyester
D. All the above
UP

Ans. D

120. Which of the following mechanism is responsible for release of encapsulated core materials?
A. By disrupting the coating by pressure
.

B. By offering permeability facilities

DR

C. By leaching of permanent fluid

D. All the above
Ans. D

121. Pre - formulation studies mainly focuson

A. Physical properties of new compound
B. Chemical properties of new compound
C. Physicochemical properties of new compound

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 MULTIPLE CHOICE QUESTIONS (PHARMACEUTICS)

D. None
Ans. C

122. Which of the following information is helpful in designing the pre-formulation evaluation of
a new drug?
A. Structure of a compound
B. Formula & molecular weight of a compound
C. Therapeutic indication of a new compound

I
D. All the above

ED
Ans. D

123. Which of the following problems commonly encountered in evaluating salt forms are

IV
A. Poor crystallinity
B. Hygroscopicity TR
C. Instability

I
&
D. All the above

ED
Ans. D
D

124. Which of the following salts generally used in pharmaceutical products?

IV
A. Acetate
B. Gluconate
IK

C. Lactate

TR
D. All the above
IT

Ans. D
N.
125. Description of the outer appearance of a crystal is known as
NA

A. Crystal habit
B. Internal structure
C. Both
A

D. None
.

Ans. A
AM
DR

126. Which of the following techniques used to prepare amorphous forms?

UP

A. Rapid precipitation
B. Lyophilization
C. Rapid cooling
D. All the above
.

Ans. D
DR

127. Amorphous forms generally having

A. Low thermodynamic energy &low solubility
B. High thermodynamic energy &high solubility
C. Both
D. None
Ans. B

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 MULTIPLE CHOICE QUESTIONS (PHARMACEUTICS)

128. Which of the following compound possess high aqueous solubility’s?

A. Hydrates
B. Anhydrates
C. Both
D. None
Ans. B

129. Which of the following properties may change with changing of the internal structure of a

I
solid?

ED
A. Melting point
B. Density
C. Optical properties

IV
D. All the above
Ans. D TR

I
&
130. Which of the following methods generally used for studying solid forms?

ED
A. DSC
B. XRD
D

C. TGA

IV
D. All the above
Ans. D
IK

TR
131. Which of the following methods generally used to measure heat loss orgain within a sample?
IT

A. DSC
B. DTA
N.
C. Both
NA

D. None
Ans. C
A

132. Which of the following co-solvent

.

can be used to increase the solubility of poor soluble drugs?

AM
DR

A. Ethanol
B. Propylene glycol
UP

C. Glycerin
D. All the above
Ans. D
.

133. Partition co-efficient generally measures

DR

A. Drug’s lipophilicity
B. Ability of drug to cross cell membrane
C. Both
D. None
Ans. C

134. Dissolution of a drug particle is described by

A. Stock’s equation

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 MULTIPLE CHOICE QUESTIONS (PHARMACEUTICS)

B. Noyes-Whitney equation
C. Drag’s equation
D. None
Ans. B

135. The effect of temperature on drug stability can be described by

A. Noyes-Whitney equation
B. Stock’s equation

I
C. Arheneous equation

ED
D. None
Ans. D

IV
136. Unequal distribution of color on a tablet, refers to
A. Picking TR
B. Mottling

I
&
C. Capping

ED
D. Sticking
Ans. B
D

IV
137. Which of the following one is responsible for sticking?
A. Excessive moisture
IK

B. Low moisture

TR
C. Both
IT

D. None
Ans. A
N.
NA

138. If the dose of a drug is inadequate, the nit generally requires the following one, to make up
its bulk
A. Binders
A

B. Disintegrants
.

C. Lubricants
AM
DR

D. Diluents
Ans. D
UP

139. Which of the following mixer is a first high shear powder blender/mixer
A. Diosna mixer
B. Plow mixer
.

C. Littleford lodige mixer

DR

D. Gral mixer
Ans. C

140. The first and most widely used diluents in tablet formulation is
A. Dextrose
B. Lactose
C. MCC
D. Starch

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 MULTIPLE CHOICE QUESTIONS (PHARMACEUTICS)

Ans. B

141. Anhydrous lactose has the advantage over hydrous lactose

A. Improved flow
B. Absence of millard reaction
C. Improved compressibility
D. High microbial load
Ans. B

I
ED
142. Which of the following is not a commercially available starch product?
A. Sta-Rx 1500
B. Celutab

IV
C. Emdex
D. Sugar tab TR
Ans. D

I
&

ED
143. Which of the following is a synthetic adhesive?
A. PVP
D

B. MC

IV
C. HPMC
D. HPC
IK

Ans. A

TR
IT

144. Which of the following is a water soluble lubricant?

A. Stearic acid
N.
B. Mineral oil
NA

C. PEG
D. Magnesium stearate
Ans. C
A
.

145. Find out the correct statements regarding a sweetener, saccharin

AM
DR

(P) It is 500 times sweeter than sucrose, but it is carcinogenic

(Q) It is 500 times sweeter than sucrose, but it has bitter taste
UP

(R) It is sweeter than sucrose, but itis safe

(S) It is sweeter than sucrose, but it is unstable
A. P, S
B. P, R
.

C. P, Q
DR

D. R, S
Ans. C

146. Aerosil is used as

A. Glidant
B. Lubricant
C. Antiadherant
D. None

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 MULTIPLE CHOICE QUESTIONS (PHARMACEUTICS)

Ans. A

147. What is the pH of duodenum?

A. 2-3
B. 7-8
D. 10
C. 4-6
Ans. D

I
ED
148. Tablets, which are placed between cheek and teeth, are known as
A. Buccal
B. Sublingual

IV
C. Lozenges
D. Troches TR
Ans. A

I
&

ED
149. Which statement is not correct?
A. Buccal routes avoids first pass metabolism
D

B. Parenteral route avoids first pass metabolism

IV
C. Sublingual route avoids first pass metabolism
D. Oral route avoids first pass metabolism
IK

Ans. D

TR
IT

150. Enteric coating is achieved by using

A. HPMC
N.
B. CMC
NA

C. CAP
D. Povidine
Ans. C
A
.

151. The disintegration time for sugarcoated tablets is

AM
DR

A. 30 minutes
B. 45 minutes
UP

C. 60 minutes
D. 75 minutes
Ans. C
.

152. Flow rate of granules from the hopper can be improved by adding
DR

A. Disintegrant
B. Glidant
C. Binder
D. Lubricant
Ans. B

153. Given below are equipment used in the manufacture of following products P-T.
Match them and find out correct answer

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 MULTIPLE CHOICE QUESTIONS (PHARMACEUTICS)

1. Zenasi (P) Tablet granules

2. Hepa filter (Q) Tablet coating
3. Chilsonator (R) Emulsion
4. Accela cota (S) Injectables (T) Capsule
A. 1-T, 2-S, 3-P, 4-Q
B. 1-P, 2-Q, 3-S, 4-R
C. 1-T, 2-R, 3-Q, 4-P
D. 1-S, 2-R, 3-P, 4-Q

I
Ans. A

ED
154. Match the ingredients according to their purpose in the formulation and find out correct set
1. Film coating (P) Sodium benzoate

IV
2. Syrups (Q) Ethyl cellulose
3. Emulsification (R) Eudragit TR
4. Enteric coating (S) Sucrose (T) Sodium oleate

I
&
A. 1-P, 2-Q, 3-R, 4-S

ED
B. 1-R, 2-S, 3-T, 4-Q
C. 1-T, 2-P, 3-S, 4-Q
D

D. 1-R, 2-S, 3-Q, 4-T22.

IV
Ans. B
IK

155. Sub coating is given to the tablets

TR
A. To increase the bulkiness
IT

B. To avoid deterioration due tomicrobial attack

C. To prevent the solubility in acidicmedium
N.
D. To avoid stickness
NA

Ans. D

156. The following ingredients are commonly used as coating agents for film coating except
A

A. CAP
.

B. Carnauba wax
AM
DR

C. HEC
D. Sodium CMC
UP

Ans. B

157. The courster process can be used to

A. Coat tablets
.

B. Determine the disintegration time

DR

C. Gas sterilize parenteral solution

D. Automatic filling of capsules
Ans. A

158. Which of the following is the first process that must occur before a drug can become available
for absorption from a tablet dosage form?
A. Dissolution of the drug in GI fluids
B. Dissolution of the drug in epithelium

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 MULTIPLE CHOICE QUESTIONS (PHARMACEUTICS)

C. Ionization of the drug

D. Disintegration of the drug
Ans. D

159. Tablets are placed into coating chamber & hot air is introduced through the bottom of the
chamber. Coating solution is applied through anatomizing nozzle from the upper end of the
chamber. This technique is called
A. Sealing before sugar coating

I
B. Coating by air suspension

ED
C. Spray-pan coating
D. Chamber coating
Ans. B

IV
160. A synthetic sweetening agent which is approximately 200 times sweeter than sucrose & has
TR
no taste is

I
&
A. Saccharin

ED
B. Aspartame
C. Cyclamate
D

D. Sorbitol

IV
Ans. B
IK

161. Shellac is used the purpose of coating tablets as

TR
A. Polishing agent
IT

B. Film coating agent

C. Enteric coating agent
N.
D. Sub-coating agent for sugarcoating
NA

Ans. C

162. Dose dumping is a problem in the formulation of

A

A. Compressed tab
.

B. Suppository
AM
DR

C. Soft gelatin capsules

D. Controlled release drug products
UP

Ans. D

163. Select the equation that gives the rate of drug dissolution from a tablet
A. Fick’s law
.

B. Henderson-Hasselbatch equation
DR

C. Noyes-Whitney equation
D. Michelis Menton equation
Ans. C

164. Which of the following substance is used as mucoadhesive

A. Acacia
B. Sodium CMC
C. Burnt sugar

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 MULTIPLE CHOICE QUESTIONS (PHARMACEUTICS)

D. Saccharin
Ans. B

165. In the preparation of multi layer tablets, one of the following is used for hydrophilic matrix
coating
A. Shellac
B. CMC
C. Stearyl alcohol

I
D. Bees wax

ED
Ans. A

166. The diameter of the mesh aperture in the I.P. disintegration apparatus is given below. Choose

IV
the correct size
A. 2 mm TR
B. 4 mm

I
&
C. 1mm

ED
D. 1.50 mm
Ans. A
D

IV
167. Diclofenac tablet with CAP has been administered to a patient. Where do you expect the
drug to be released?
IK

A. Stomach

TR
B. Oral cavity
IT

C. Small intestine
D. Liver
N.
Ans. C
NA

168. Which of the following flavor is used in a formulation containing sour taste?
A. Wild cherry
A

B. Vanilla
.

C. Citrus
AM
DR

D. Chocolate
Ans. C
UP

169. Durability of a tablet to combined effects of shock & abrasion is evaluated by using
A. Hardness tester
B. Disintegration test apparatus
.

C. Friabilat or
DR

D. Screw guage
Ans. C

170. A retardant material that forms a hydrophilic matrix in the formulation of matrix tablets is
A. HPMC
B. CAP
C. Polyethylene
D. Carnauba wax

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 MULTIPLE CHOICE QUESTIONS (PHARMACEUTICS)

Ans. A

171. A water soluble substance used as coating material in microencapsulation process is

A. Polyethylene
B. Silicone
C. HEC
D. Paraffin
Ans. C

I
ED
172. One of the following is used as a Ph Dependant controlled release excipient
A. Carnauba wax
B. HPMCP

IV
C. MC
D. Glyceryl mono stearate TR
Ans. D

I
&

ED
173. In the tablet coating process, inadequate spreading of coating solution before drying causes
A. Orange peel effect
D

B. Sticking effect

IV
C. Blistering effect
D. Picking effect
IK

Ans. A

TR
IT

174. Crown thickness of a tablet is measured by

A. Micrometer
N.
B. Pychnometer
NA

C. Hydrometer
D. All the above
Ans. B
A
.

175. Friabilator is operated at

AM
DR

A. 100 RPM
B. 75 RPM
UP

C. 50 RPM
D. 25 RPM
Ans. D
.

176. Enteric coated tablet disintegrate in……hours in simulated intestinal fluid

DR

A. 1
B. 2
C. 3
D. 4
Ans. A

177. In dissolution test, flask is maintained at

A. 37oC ± 0.5oC

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 MULTIPLE CHOICE QUESTIONS (PHARMACEUTICS)

B. 41oC ± 1oC
C. 39oC ± 0.6 oC
D. 40oC ± 1oC
Ans. A

178. Capping is prevented by using one of the following punches

A. Flat
B. Circular

I
C. Square

ED
D. Rectangular
Ans. A

IV
179. Plating of punch faces are done by
A. Chromium TR
B. Zinc

I
&
C. Iron

ED
D. All
Ans. A
D

IV
180. Sta-Rx-1500 contains ……% of moisture
A. 15
IK

B. 10

TR
C. 18
IT

D. 50
Ans. B
N.
NA

181. Acacia trgacanth is used in the concentration of

A. 10%-25 %
B. 60%-70 %
A

C. 40%-50 %
.

D. 90%
AM
DR

Ans. A
UP

182. Starch on heating hydrolyze into

A. Glucose
B. Fructose & Sorbose
C. Fructose & Mannose
.

D. Dextrin & Glucose

DR

Ans. D

183. PH of the small intestine is

A. 1-2
B. 3-4
C. 6
D. 7-8
Ans. D

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 MULTIPLE CHOICE QUESTIONS (PHARMACEUTICS)

184. Aqua coat is a

A. 30% w/v of ethyl cellulose dispersion
B. Solution of HPMC
C. 2% w/v of methyl cellulose dispersion
D. None
Ans. B

I
195. Lozenges were originally named as

ED
A. Capsule
B. ODT
C. Pastillies

IV
D. Sustained axn tab
Ans. C TR

I
186. Implantation tab are NMT……..mm in length

&

ED
A. 20
B. 100
D

C. 40

IV
D. 8
Ans. C
IK

TR
187. Seal coating is done by using
IT

A. Shellac
B. Acacia
N.
C. Gelatin
NA

D. None
Ans. A
A

188. Sub coating is done to

.

A. Round the edges

AM
DR

B. Increase the bulk of tablet

C. Both a & b
UP

D. Make water resistant

Ans. C

189. CAP dissolves at PH

.

A. Above 6
DR

B. Below 6
C. 4
D. 2
Ans. A

190. Which of the following one is used as opacifier

A. TiO2

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 MULTIPLE CHOICE QUESTIONS (PHARMACEUTICS)

B. Mgo
C. Siliactes
D. All of the above
Ans. A

191. Green bone is a source of

A. Type A Gelatin
B. Type B Gelatin

I
C. Both

ED
D. None
Ans. B

IV
192. Empty capsule has moisture content in the range of
A. 60% TR
B. 12%-15 %

I
&
C. 50%- 70%

ED
D. 30%
Ans. C
D

IV
193. Which treatment is used for solubility of gelatin
A. Heat
IK

B. Formalin

TR
C. Water
IT

D. Alcohol
Ans. B
N.
NA

194. Which of the following is used to fill powdered dry solid into soft gelatin capsule
A. Aceo gel
B. Rotobil
A

C. Rotosort
.

D. Rotoweigh
AM
DR

Ans. A
UP

195. Sealing of capsule is achieved by

A. 100 oC
B. 20 oC
C. 37 oC - 40 oC
.

D. 70 oC
DR

Ans. C

196. Moisture content is determined by

A. K-F Method
B. Gas Chromatography
C. Both
D. None
Ans. A

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 MULTIPLE CHOICE QUESTIONS (PHARMACEUTICS)

197. Foam stability is measured by

A. IR Spectroscopy
B. UV Spectroscopy
C. Rotational viscometers
D. All
Ans. C

I
198. Particle size is determined by

ED
A. Gas Chromatography
B. Cascade impactor
C. Light scatter decay

IV
D. Both b & c
Ans. D TR

I
&

ED
199. Chewable tablet contains the following base
A. Manitol
D

B. Glucose

IV
C. Lactose
D. None
IK

Ans. A

TR
IT

200. Which of the following is not added inlozenges?

A. Sweetener
N.
B. Binder
NA

C. Disintegrant
D. All
Ans. C
A
.

201. Enteric coated tablet is disintegrated in

AM
DR

A. Stomach
B. Liver
UP

C. Intestine
D. Mouth
Ans. C
.

202. Micromeritics is the study of

DR

A. Big particles
B. Small particles
C. Both
D. None of these.
Ans. B

203. The size and surface area of a particles in ………….?

A. Physical

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 MULTIPLE CHOICE QUESTIONS (PHARMACEUTICS)

B. Chemical
C. Pharmacologic properties of products
D. All of these.
Ans. D.

204. Particle size of product can affect its release from dosage forms administered orally by
A. Medically
B. Clinically

I
C. Both

ED
D. None of these.
Ans. B

IV
205. Frequency distribution curve is obtained when
A. Number of particles is plotted against the mean size range
TR
B. Mean size range is plotted against the number of particles

I
&
C. Number of particles and the mean size are on x-axis

ED
D. Both A and B
Ans. D
D

IV
206. Methods for determining particle size include
A. Optical microscopy
IK

B. Sieving

TR
C. Sedimentation
IT

D. All of these
Ans. D
N.
NA

207. Ordinary microscope can measure the particle size between range
A. 0.2 to 100 m
B. 0.2 to 100 mm
A

C. 0.2 to 100 µm
.

d) 0.2 to 100 nm
AM
DR

Ans. C
UP

208. The size of particle is measured by microscope with the help of

A. Eye-piece
B. Micro-meter
C. Eye-piece fitted with micro-meter
.

d) None
DR

Ans. C

209. Sieving method uses a series of standard sieves calibrated by the

A. National Bureau of standards
B. IUPAC
C. Any of these
D. None
Ans. A

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 MULTIPLE CHOICE QUESTIONS (PHARMACEUTICS)

210. Order of sieves in sieving is

A. Coarse, moderately coarse, moderately fine, fine, very fine
B. Moderately coarse, coarse, moderately fine, fine, very fine
C. Moderately coarse, coarse, fine, moderately fine, very fine
D. Coarse, moderately coarse, fine, moderately fine, very fine
Ans. A

I
211. Sieving errors can arise by factors including

ED
A. Sieve loading & duration
B. Intensity of agitation
C. A & b

IV
D. None
Ans. C TR

I
&
212. The particle size in sub sieve range can be found by gravity sedimentation as expressed in
A. Van’t hoff factor

ED
B. Ohm’s law
D

C. Graham’s law

IV
D. Stoke’s law
Ans. D
IK

TR
213. Andreasen Apparatus works under the principle of
IT

A. Microscopy
B. Sedimentation
N.
C. Sieving
NA

D. All of above
Ans. B
A

214. Any instrument used for measuring volume of particle is……..

.

A. Andreasen apparatus
AM
DR

B. Coulter counter
C. Fisher sub sieveseizer
UP

D. None
Ans. B

215. Granulators are used for

.

A. Making particles longitudinal

DR

B. Cuboidal
C. Spherical
D. Elliptical
Ans. C

216. The specific surface is the ……….

A. Surface area per unit volume
B. Surface area per unit weight

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 MULTIPLE CHOICE QUESTIONS (PHARMACEUTICS)

C. Both A and B
D. None of these
Ans. C

217. Methods for determining surface area are

A. Absorption method
B. Adsorption method
C. Air permeability method

I
D. B & C

ED
Ans. D

218. The adsorbed layer in adsorption method is monomolecular at

IV
A. Very low pressure
B. Low pressure TR
C. High pressure

I
&
D. Very high pressure

ED
Ans. B
D

219. The adsorbed layer in adsorption method is multimolecular at

IV
A. Very low pressures
B. Low pressures
IK

C. Higher pressures

TR
D. All of above
IT

Ans. C
N.
220. An instrument used to calculate the surface area of particles is
NA

A. Quantasorb QS-16
B. Quanta-adsorb QD-16
C. Boyton apparatus
A

D. Quanta-apparatus
.

Ans. A
AM
DR

221. In adsorption method the particle whose surface area is to be measured is taken as
UP

A. Adsorbate
B. Adsorbent
C. Any of above
D. Both of above
.

Ans. B
DR

222. Particle size of colloids ………….,

A. 1 nm to 0.5µm
B. 1 µm to 0.5mm
C. 1 mm to 0.5m
D. 1 m to 0.5mm
Ans. A
.

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 MULTIPLE CHOICE QUESTIONS (PHARMACEUTICS)

223. The process which it consisted of at least two phases with one or more disperse phase in a
single dispersion medium is called
A. Disperse phase
B. Dispersion medium
C. Dispersion
D. All of these
Ans. C

I
224. How many types of dispersion?

ED
A. 1
B. 2
C. 3

IV
D. 4
Ans. C (molecular dispersion, colloidal dispersion, coarse dispersion)
TR

I
&
225. Molecular dispersion ranges from.........

ED
A. 1 to 500nm
B. ‹500nm
D

C. ‹1nm

IV
D. None of these
Ans. C
IK

TR
227. The increasing trend of diameter is
IT

A. Molecular dispersion, Colloidal dispersion, Coarse dispersion.

B. Colloidal dispersion, coarse dispersion, molecular dispersion.
N.
C. Corse dispersion, molecular dispersion, colloidal dispersion.
NA

D. All of these
Ans. A
A

228. The dispersion medium in blood is

.

A. Platelets
AM
DR

B. Serum
C. Plasma
UP

D. Oxygen
Ans. C

229. The best example of all dispersion is..........

.

A. Oxygen
DR

B. Blood
C. Proteins
D. All of these
Ans. B

230. Molecular dispersion easily passes through.........

A. Electron microscope

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 MULTIPLE CHOICE QUESTIONS (PHARMACEUTICS)

B. Ultra filtration
C. Filter paper
D. All of these
Ans. D

231. No diffusion takes place in

A. Molecular dispersion
B. Colloidal dispersion

I
C. Coarse dispersion

ED
D. None of these
Ans. C

IV
232. Osmoses cannot formed when particles are in......
A. Equilibrium state TR
B. Random state

I
&
C. Both A and B

ED
D. None of these
Ans. A
D

IV
233. Microscopic particles can be separated by
A. Ultra filtration
IK

B. Filtration

TR
C. Dialysis
IT

D. All of above
Ans. B
N.
NA

234. Colloids are

A. Can’t be observed by ordinary microscope
B. Detected under ultra microscope
A

C. Both A and B
.

D. None
AM
DR

Ans. C
UP

235. Colloids can pass through

A. Filter paper
B. Semi-permeable membrane
C. Both A and B
.

D. None
DR

Ans. A

236. Colloids can’t pass through

A. Filter paper
B. SEMI-permeable
C. Both a and b
D. None of these
Ans. B

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 MULTIPLE CHOICE QUESTIONS (PHARMACEUTICS)

237. Diffusion of colloids is

A. Very slow
B. Slow
C. Fast
D. Very fast
Ans. A

I
238. Cheese is an example of

ED
A. Molecular dispersion
B. Colloidal
C. Coarse

IV
D. All of above
Ans. B TR

I
&
239. Example of colloidal dispersion is

ED
A. Oxygen molecules
B. Milk
D

C. None

IV
D. All
Ans. B
IK

TR
240. …………. is not an example of colloidal dispersion
IT

A. Cheese
B. Milk
N.
C. Synthetic polymers
NA

D. RBC’s
Ans. D
A

241. Scattering of light form colloidal particles is ………..

.

A. Faraday Tyndall effect

AM
DR

B. Van’t hoff factor

C. Van’t hoff dispersion
UP

D. None
Ans. A

242. Faraday Tyndall effect is observed by………

.

A. Light microscopy
DR

B. Ultramicroscope
C. Radiography
D. None
Ans. B

243. Who invented ultra microscope………..

A. Zsigmonday

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 MULTIPLE CHOICE QUESTIONS (PHARMACEUTICS)

B. Faraday
C. Tyndall
D. Ohm
Ans. A

244. As a result of Tyndall effect………..

A. Dark spots
B. Bright spots are formed

I
C. Both A and B

ED
D. Any of A and B
Ans. B

IV
245. The process in which dispersed phase is mix in a suitable solvent the process is known as
A. Salvation TR
B. Dehydration

I
&
C. Hydration

ED
D. All of these
Ans. A
D

IV
246. The instrument which is use to reduce the particle size is called………
A. Size reduction
IK

B. Milling

TR
C. Mold
IT

D. All of above
Ans. B
N.
NA

247. The process in which we converted coarse particles into colloidal then it is called
A. Milling
B. Size reduction
A

C. Size oxidation
.

D. None of these
AM
DR

Ans. B
UP

248. Any type of chemical compound that posses two distinct regions that is hydrophilic and
hydrophobic portion within same molecule is called
A. Amphiphyllic
B. Electrophyle
.

C. Both A and B
DR

D. None of these
Ans. A

249. Amphiphyllics are also called

A. Association colloidal
B. Surface active agents
C. Amphipathics
D. All of above

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 MULTIPLE CHOICE QUESTIONS (PHARMACEUTICS)

Ans. D

250. Inter phase is composed of

A. Water phase
B. Air phase
C. Both A and B
D. None of these
Ans. C

I
ED
251. The large phase is called
A. Inter phase
B. Bulk phase

IV
C. Both A and B
D. None of these TR
Ans. B

I
&

ED
252. The point at which bulk phase and air, water inter phase become saturated is called
A. CMC
D

B. Bulk phase

IV
C. Inter phase
D. None of these
IK

Ans. A

TR
IT

253. It is an aggregation of surfactant molecule in a colloidal liquid then it is called

A. CMC
N.
B. Micelles
NA

C. Aggregation number
D. None of these
Ans. B
A
.

254. Dispersed phase and dispersion medium of smoke are

AM
DR

A. Solid and liquid

B. Liquid and liquid
UP

C. Solid and gas

D. Gas and gas
Ans. C
.

255. Light scattering in colloidal system is known as

DR

A. Brownian motion
B. Faraday-Tyndal effect
C. Coagulation
D. Electrophoresis
Ans. B

256. Adsorption is the process of

A. Repulsion

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 MULTIPLE CHOICE QUESTIONS (PHARMACEUTICS)

B. Addition
C. Adhesion
D. None of these
Ans. C

257. Surface on which ions, atoms or molecules accumulate

A. Adsorbent
B. Adsorbate

I
C. Specific surface

ED
D. All
Ans. A

IV
258. Adsorbate are ions, atoms or molecules
A. Which allow accumulation on their surface
TR
B. Which accumulate on a specific surface

I
C. Which don’t accumulate

&

ED
D. Both
Ans. B
D

IV
259. If both adsorption & absorption are going side by side then it is
A. Disorption
IK

B. Desorption

TR
C. Sorption
IT

D. Resorption
Ans. C
N.
NA

260. Reverse of adsorption is called

A. Disorption
B. Desorption
A

C. Sorption
.

D. Resorption
AM
DR

Ans. B
UP

261. Vander-wall adsorption is synonym of

A. Physical adsorption
B. Chemical adsorption
C. Physi-adsorption
.

D. A& C
DR

Ans. D

262. Physi-adsorption is effected by

A. Temperature only
B. Pressure only
C. Temperature and pressure
D. None
Ans. C

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 MULTIPLE CHOICE QUESTIONS (PHARMACEUTICS)

263. Strong bonding is present in

A. Chemical adsorption
B. Physical adsorption
C. Vander-wall adsorption
D. A&C
Ans. A

I
264. Absorption is …………….. phenomenon

ED
A. Bulk
B. Surface
C. Phase difference

IV
D. Bulk & phase
Ans. A TR

I
&
265. Adsorption has

ED
A. Uniformity
B. Non-uniformity
D

C. Bulk uniformity

IV
D. A & C
Ans. B
IK

TR
266. Chemical adsorption involves ……. Bonding
IT

A. Hydrogen
B. Ionic
N.
C. Covalent
NA

D. Ionic & covalent

Ans. B
A

267. Chemical adsorption is

.

A. Reversible
AM
DR

B. Irreversible
C. Mostly reversible
UP

D. Some-times irreversible
Ans. B

268. Disposable syringe made up of

.

A. Polypropylene
DR

B. Transparent polystyrene
C. Glass
D. Poly tetra chloro ethylene
Ans. A

269. Water attack test is used to identify the alkalinity in

A. Type – I Glass
B. Type – II Glass

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 MULTIPLE CHOICE QUESTIONS (PHARMACEUTICS)

C. Type – III Glass

D. All the 3 types
Ans. B

270. As per G.M.P permitted limit of solid contents in water for injection is
A. 100 ppm
B. 1.0 ppm
C. 0.1 ppm

I
D. 10 ppm

ED
Ans. D

271. Sterilization temperature for aqueous solution in autoclave (moist heat) is

IV
A. 72oC
B. 121oC TR
C. 147oC

I
&
D. 160oC

ED
Ans. B
D

272. Sterility test for the material meant for surgical suture required incubation for

IV
A. 7 Days
B. 14 Days
IK

C. 21 Days

TR
D. 28 Days
IT

Ans. B
N.
273. An amphoteric surfactant used in pharmaceutical disperse system is
NA

A. Bile salt
B. Lecithin
C. Sorbitan monolaurate
A

D. Sorbitan monostearate
.

Ans. B
AM
DR

274. An abrasive used in dentifrices is

UP

A. Dicalcium Phosphate
B. Sodium carboxy methyl cellulose
C. Sodium Lauryl Sulphate
D. Dioctyl Sodium sulfosuccinate
.

Ans. A
DR

275. Florentine receiver is used to separate the liquids based on

A. Molecular weight
B. Sedimentation rate
C. Density
D. Freezing point
Ans. C

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 MULTIPLE CHOICE QUESTIONS (PHARMACEUTICS)

276. The official dissolution test apparatus contains cylindrical vessel and the lower edge of the
blade is positioned from inside bottom of the vessel at
A. 18 to 22mm
B. 23 to 27mm
C. 20 to 24mm
D. 25 to 29mm
Ans. B

I
277. As per Drugs and Cosmetics Act and Rules, the Good Manufacturing Practice is included

ED
under Schedule
A. W
B. P

IV
C. S
D. M TR
Ans. D

I
&

ED
278. In multistation punching machine, the upper as well as lower punches are connected by
A. Cams
D

B. Turrets

IV
C. Wire meshes
D. Revolving belts
IK

Ans. D

TR
IT

279. As per the Drugs and Cosmetics Act, the HEPA filters are required to filter the air in the
pharmaceutical manufacturing unit. Grade A filter is used for
N.
A. Aseptic preparation and filling
NA

B. Background room used for preliminary activities

C. Filtering liquid preparations
D. Handling of components after washing
A

Ans. A
.

AM
DR

280. Lyposomes are used as carriers for drugs and macromolecules in pharmaceutical
formulations. They are
UP

A. Phospholipids dispersed gently in aqueous medium to obtain multilamellar vesicles

B. Hydrophilic or lipophilic polymer matrix with a drug reservoir
C. A shallow compartment moulded from a drug impermeable system and rate controlling
polymeric membrane
.

D. Microporous membrane made from ethylene / vinyl acetate polymer

DR

16. Due to which factors, petrolatum is most widely used as a hydrocarbon basic in ointments
A. Its consistency
B. Its neutral characteristics
C. Its ability to spread easily on the skin
D. All
Ans. D

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