New Scientist - 27 06 2020 PDF
New Scientist - 27 06 2020 PDF
New Scientist - 27 06 2020 PDF
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News Features
12 Rise of the dinosaurs 28 Your thinking body
Did surging sea levels help News When it comes to consciousness,
the giant reptiles dominate? your brain isn’t the whole story
Views
The back pages
21 The columnist
Graham Lawton on Black Lives 53 Puzzles
Matter’s environmental justice Cryptic crossword and the quiz
24 Culture 54 Cartoons
Sci-fi’s suggestions for how Life through the lens of
to avoid a techno-apocalypse Tom Gauld and Twisteddoodles
25 Culture 55 Feedback
NASA/JPL-CALTECH/MSSS
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on New Scientist
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The leader
THE UK has three, the US 11 and Australia That these symptoms don’t tally to a shortlist of common symptoms
14. What are these? Covid-19 symptoms. with information published by official was arguably the most effective way
That is according to advice from each guidelines is problematic. Not only to identify and act on new cases.
country’s health body. How can the same does it leave thousands of people who But now we have evidence that
disease affect people so differently in are ill with little or no help and support, symptoms can be varied and we must
each country? The answer is: it doesn’t. it also jeopardises our efforts to contain make sure we help those who are still
The disparity is a reflection of the spread of the virus. ill weeks or even months after being
how little we have known about the infected. Crucially, unless we officially
symptoms of covid-19, until now. “Strange symptoms include recognise – and publicise – all symptoms
What we initially thought of as a exhaustion, numbness, brought on by the coronavirus, we don’t
respiratory disease is in fact a much extreme weight loss, stand a chance of identifying those
more formidable enemy. It can kill brain fog and rashes” who may have caught it, in order to
via a two-pronged attack, through test them and trace their contacts.
provoking our immune systems When people started sharing unusual As the UK attempts to use its faltering
and disrupting blood clotting (page 8). symptoms on forums at the start of the test and trace scheme to prevent
And for some people, covid-19 outbreak, it is understandable that they a second wave of cases (see page 7),
results in symptoms that can be strange, were dismissed by some. People were it seems ill-advised that the country
debilitating and long-lived (see page 34). in a state of hypervigilance about their still officially lists just three symptoms.
The list includes exhaustion, numbness, health, and few were getting tested – in Effective contact tracing will require
diarrhoea, extreme weight loss, brain the UK at least – especially not those listening to those who are sick, to
fog, muscle pain and rashes. with odd-sounding complaints. Sticking protect others from a similar fate. ❚
News Coronavirus
Social distancing
instructions on the
streets of Watford, UK
News Coronavirus
Treatments
and clots. I think we are pretty cases they overreact, pumping out Peter Horby at the University of
close to working it all out.” too many cytokines – chemicals Oxford, in a statement.
The coronavirus enters our that recruit yet more immune The finding is good news, but
body through cells lining the cells in a vicious circle known as a isn’t enough on its own. Other
nose or mouth by latching on to cytokine storm. “There is fluid and groups are looking for ways to
a molecule on their surface called inflammatory cells flooding into tackle the way covid-19 leads to
Briefing
bear the ACE2 receptor, argued TESTS for coronavirus Home swab tests can reveal
Peter Carmeliet at KU Leuven antibodies vary in accuracy and if you are currently infected
in Belgium in a review article may not be useful for everyone. with the coronavirus
last month (Nature Reviews Here’s what you need to know.
Immunology, doi.org/dz55). in the UK and the rest of Europe.
Part of the problem is that ACE2 What can a coronavirus But that doesn’t mean there has
receptors on blood vessel cells test tell me? been independent validation
normally regulate hormones There are two main kinds of these tests. “There’s no
that affect clotting, and this is of tests. One looks for the virus scrutiny,” says Jon Deeks at
JULIAN CLAXTON/ALAMY
prevented by the virus binding to in nose or throat swabs, which the University of Birmingham,
them. The virus also kills blood can reveal if you are currently UK. What’s more, he says many
vessel cells. “That’s a very strong infected. In many countries, clinics offering antibody tests
stimulus to the formation of tests for active infections are don’t reveal which specific
blood clots,” says Carmeliet. free, so there is no need to pay. test they use. Many countries,
Most people in intensive care The other type looks in your including the US and Australia,
are already given low doses of the blood for the antibodies your others. Plus, your test results have stricter regulations.
blood-thinning drug heparin, as immune system makes to attack might not be correct.
being immobile and having a lot the coronavirus. This can reveal Do we know how accurate
of medical procedures raises the if you were infected but have How do I get an antibody test? any of the tests are?
risk of clots forming. Now, many since recovered. It can take In the UK, your only option is Public Health England has
hospitals are increasing the several weeks to produce to have a blood sample taken evaluated five tests developed
amount of heparin given to antibodies, so there is little by a qualified healthcare worker by Roche, Abbott, Euroimmun,
their covid-19 patients, as well point in doing antibody tests and then sent off for testing. DiaSorin and Ortho Clinical.
as monitoring the “stickiness” during or soon after an illness Some private doctors and clinics These tests have a sensitivity
of their blood so the dose can you suspect could be covid-19. will send someone to your of around 70 per cent or higher
be finely adjusted. home to take the sample. after about 14 days of infection,
This is now standard practice Can an antibody test tell me if meaning 30 per cent or fewer
at University Hospitals Leuven in I’m immune to the coronavirus? Aren’t there home testing kits? results are false negatives and
Belgium, says intensive care doctor No. “A positive result may not The antibody tests designed to wrongly identified as not having
Geert Meyfroidt. He believes this mean a person is immune,” be done at home haven’t proved
is behind the relatively low death says the UK’s Medicines and reliable so far. In the UK, it is “A positive antibody
rate for the hospital’s covid-19 Healthcare products Regulatory illegal to sell them but some test may not mean a
patients of less than 25 per cent. Agency (MHRA). People who companies still do. “We strongly person is immune to
Other strategies are being have recovered should be discourage organisations and the coronavirus“
investigated worldwide against immune for a while, but we individuals from purchasing
both blood clotting and cytokine don’t know how long immunity unvalidated antibody tests,” the virus. The tests have a
storms, in the hope that the death against this coronavirus lasts says a UK Department of Health specificity of about 98 per cent
rate can be lowered further still. yet. With other coronaviruses, and Social Care spokesperson. or more – so less than 2 per cent
Beyond these, alternative studies show people can be of results are false positives.
approaches include using reinfected as soon as six months Can I take a blood sample myself?
antibodies from recovered after the initial infection. Some companies were sending If I get a positive test result, how
covid-19 patients and antiviral out self-testing kits that use sure can I be that it is correct?
drugs like remdesivir, which has What use are antibody tests? a drop of blood from a finger This depends on your likelihood
been found to shorten the time For policy-makers, it is useful to prick. However, on 29 May, the of having been infected, says
people spend in hospital or know what percentage of people MHRA ordered companies to Babak Javid at Tsinghua
require extra oxygen. have been infected. But until we stop until it has been shown University in China. If you live
One problem in some European find out more about immunity that antibody tests work with in London and recently had a
countries, such as Belgium, is that to coronavirus, antibody tests blood samples taken this way. severe respiratory infection,
they now have so few new cases of are less useful for individuals. a positive result is likely to be
coronavirus, it is hard to carry out You shouldn’t alter your Which antibody test is best? correct. But if you have been
trials for potential treatments, says behaviour based on a positive So far, 219 antibody tests have shielding in Cornwall with no
Meyfroidt. “But when it comes antibody test. You risk getting a CE certification mark, which symptoms, it could well be
back, we need to be ready.” ❚ infected again, or infecting means they can legally be offered wrong, says Javid. ❚
News Coronavirus
South America
NEW ZEALAND has been widely Baker was inspired by the The country has recorded only
praised for its aggressive response World Health Organization’s 1515 covid-19 cases and 22 deaths
to covid-19. As New Scientist report from its joint mission to date, and hasn’t had any new,
went to press, the country had to China in February, which locally acquired cases since 22 May.
just 10 active cases. But Michael documented how the country The current active cases are all
Baker, the doctor who formulated largely contained covid-19 when citizens in supervised quarantine
New Zealand’s elimination it was already in full flight. This after returning from overseas.
strategy, says that even some of convinced Baker that New Zealand On 8 June, New Zealand lifted
his colleagues initially thought it could also stop the virus from all its restrictions except for
UNIVERSITY OF OTAGO
was too radical a plan and resisted spreading and even wipe it out its border control measures.
its implementation. “Some likened entirely if it implemented a strict “There was this amazing
it to using a sledgehammer to kill a lockdown as soon as possible. sense of relief,” says Baker.
flea,” he says. Other experts, however, He is proud of New Zealand’s
The first case of covid-19 in argued that New Zealand success, but says it is important
New Zealand was recorded on should take a lighter approach Profile not to become complacent or
28 February. Like most countries, like Sweden, which never fully Michael Baker is a professor of smug. Baker warns that other
it initially planned to gradually locked down. Many believed the public health at the University of countries that have seemingly got
tighten its control measures as spread of covid-19 was inevitable Otago, New Zealand, and an adviser on top of the virus, such as China
the virus gained momentum. But and that an elimination strategy to the government of New Zealand. and South Korea, have experienced
Baker, a public health expert at the would “never work”, says Baker. subsequent outbreaks.
University of Otago who is on the Others thought that locking down exchange programme, which Last week, New Zealand
government’s covid-19 advisory the country would lead to mass has meant that rates of HIV was shaken by the news that
panel, believed that this was the unemployment, poverty and among injecting drug users two women had tested positive
wrong approach. “I thought we suicide, which would outweigh the in New Zealand are some for covid-19 after returning from
should do it in the reverse order benefits of containing the virus. of the lowest globally. the UK and being allowed to leave
and throw everything at the The government ultimately On 25 March, when New Zealand quarantine early to visit a dying
pandemic at the start,” he says. decided to go with Baker’s advice, had only 205 covid-19 cases and relative. Extensive contact tracing
possibly because of his public no deaths, the government is now under way.
Wellington, New Zealand, health track record. In the 1980s, implemented one of the strictest To guard against a second
in May as restrictions for example, he helped establish lockdowns in the world, only wave in New Zealand, Baker thinks
began to be eased the world’s first national needle permitting people to leave their masks should be worn on public
homes for essential reasons like
buying food and going to the “I thought we should
doctor. This followed the closure do it in the reverse order
of New Zealand’s borders to and throw everything at
non-nationals on 19 March. the pandemic at the start”
Baker felt “very moved” by the
government’s decision, but also transport, aircraft and at border
anxious, because he didn’t know control and quarantine facilities.
if it would work. “As a scientist, you For him, one positive thing
feel very worried if you’re giving to come out of the pandemic is
advice when the evidence base that it has shown how proactive
isn’t totally there yet, particularly government measures can protect
when it’s something that could the public from avoidable hazards.
be harmful to people,” he says. Baker hopes this will inspire more
MARTY MELVILLE/AFP VIA GETTY IMAGES
News
Space
SPARKS may be flying on Mars. surface. To do this, they used the researchers were able to problem for the electronics
The grains of dust there can rub bursts of carbon dioxide in a detect them with an antenna embedded in the suits, she says.
together and become electrically low-pressure chamber to create (arxiv.org/abs/2006.01978). Electric charges could also
charged, which could cause a fountain of artificial Mars dust This build-up of electric cause chemical reactions in
chemical reactions that would and measured the electrical effects charge could be an issue for Martian dust. Wang and her
make it difficult to spot signs of the particles rubbing together. human exploration of Mars. colleagues have found that small
of life on the surface. The charges had about the “We are eventually going to electric discharges like the ones
When grains of dust rub same strength that you can send humans to Mars, and all this demonstrated in Méndez Harper’s
together, they can build up typically get from rubbing static electricity will be pretty hard experiments could be key to the
an electric charge in the same two materials together to create to deal with for a human mission,” reactions that release chlorine
way that shuffling your feet on static electricity. The sparks says Alian Wang at Washington from other compounds on the
the carpet can build up static produced weren’t visible, but University in Missouri. Moon Martian surface.
electricity. Those grains can then dust collected in the creases of They have also found that those
release the charge in sparks. The surface of Mars the Apollo astronauts’ suits: if same reactions generate highly
Experiments have hinted that might be crackling Mars dust collects that way too, reactive particles that could
the red dust coating the surface with static electricity the sparks it releases could be a drastically affect the surface
of Mars could be electrified like chemistry of the Red Planet,
this, but for the most part those including destroying the
experiments have included chemicals that are considered
other factors that could have signs of possible life (Journal
influenced the accumulation of Geophysical Research: Planets,
of electric charge. For instance, doi.org/dzs8).
if dust particles touch the walls “If each storm and each dust
of the experiment’s containers, devil induces lots of chemical
they could build up charge. reactions, then searching for
Joshua Méndez Harper at the signs of life would be very hard,”
University of Oregon and his says Wang. “We could go to Mars
NASA/JPL-CALTECH/MSSS
Palaeontology
Rising sea levels may In 2019, researchers led by were replaced by more swamp-like seabed, such as rising underwater
Tore Klausen, then at the University plants, says Klausen, before the mountains, were responsible
have led to global of Bergen in Norway, reported area became marine. (Terra Nova, doi.org/dzpw).
dinosaur domination that in the late Triassic there was The floods were caused by rising The huge floods must have
a vast river delta in what is now the seas. Today, the seas are rising had a big impact on land animals,
VAST floods caused by sea level Barents Sea between Norway and because the water is warming and says Klausen, which could explain
rise may have helped dinosaurs Russia. The floodplain was 10 times expanding, and because ice caps how dinosaurs came to dominate.
take over the planet. the size of the Amazon delta. are melting, but in the Triassic, the Klausen suggests that other
The first dinosaurs evolved Klausen and his colleagues have climate was consistently warm reptiles were specialised in
early in the Triassic period, about now found that most of this area and there were no ice caps to melt. floodplain environments and
245 million years ago, but it took flooded and became a shallow Instead, Klausen says “global became marginalised when this
about 20 million years for them sea about 227 million years ago. tectonic events” that changed the habitat was drowned. In contrast,
to dominate land ecosystems. Sediments characteristic of land dinosaurs may have been better
Palaeontologists are unsure were replaced by traces of wetlands “The huge floods must have able to cope with hills and deserts.
why the dinosaurs came to be so and then seabed. Fossil pollen affected land animals, “They were occupying niches
numerous and diverse, when other revealed that the plants also perhaps explaining the gradually,” says Klausen. ❚
reptile groups like crocodiles didn’t. changed: those adapted to dry land rise of dinosaurs” Michael Marshall
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News Insight
Racial bias
SOLSTOCK/GETTY IMAGES
striking over racism in their fields.
They have good reason: the odds
of succeeding in science are still
overwhelmingly stacked against
black people and those from other
ethnic minority groups.
In the UK, around 7 per cent Healthcare biochemists Osman thinks economics and so put up a shield whenever
of undergraduate students are at work at a research mental health are two big reasons people talk about it,” he says.
black, matching the percentage of facility in London why there aren’t more black Funding figures highlight
black people aged 18 to 24. But the people in science. “There’s a further structural barriers
number plummets when you look mental health impact to being in science. In the UK, senior
at PhD students at top universities, black,” she says. “Knowing your researchers from an ethnic
according to figures the UK’s history comes from slavery and minority are half as likely to have
Higher Education Statistics colonialism, and then being success with a research funding
Agency provided to New Scientist. in white spaces and having to application as their white peers,
For the past five years, the
proportion of black PhD students
at Russell Group universities – seen
as the UK’s most prestigious – has
7%
Undergraduate students in
pretend that it doesn’t matter.
It’s exhausting.”
Daniel Akinbosede at the
University of Sussex in the UK
according to figures from UK
Research and Innovation (UKRI)
for the financial year 2018-2019.
And if they succeed, they get
stagnated at around 2 per cent. the UK who are black says the cost of doing a PhD may £564,000 on average, versus
The figures are even lower at some be a luxury that some black people £670,000 for white researchers.
2%
institutions: the five-year average can’t afford. One of the main
for UK-born black students at the reasons he applied to do a PhD
University of Oxford is 1.3 per cent, was because an academic of
Funding disparities
for example. Black PhD students at the UK’s Indian descent encouraged him. These figures reveal the racial
The story is similar in the US, most prestigious universities He thinks white academics discrepancies in funding from
where African Americans make up often overlook black, Asian and the UK’s seven main research
6.5%
nearly 13 per cent of the population, minority ethnic (BAME) students, councils, but also obscure
but win only 6.5 per cent of and so black students are less disparities among people
doctorates earned, according likely to consider pursuing a of different ethnic groups.
to the latest statistics from the Doctorates earned in the US career in science. “Scientists think The figures bundle all BAME
National Science Foundation. by African Americans they’re too smart to be racist and researchers together. “The stats
look terrible. But they also funding bodies. Students who By comparison, an equivalent universities with roles at senior
aggregate, because they’d look have finished their PhD and are scheme to recognise universities management level – categorised
even worse otherwise,” says looking to apply for a fellowship removing barriers for BAME as managers, directors and senior
Michael Sulu at University College need to be put forward by their staff and students has seen just officials – less than 5 per cent
London, who is a member of The institution, as part of internal 14 universities receive an award for identify themselves as Asian,
Inclusion Group for Equity in competition. “In some their efforts. All 14 achieved only mixed or other. None is black. Out
Research in STEMM (TIGERS). administrations it’s robust, in the “bronze” award for the Race of 21,520 professors, 0.65 per cent
One defence deployed against many it’s a tap on the shoulder,” Equality Charter. None has hit identify as black, 6.3 per cent as
separating out the figures is that Hussain says of the process, “silver” and the standards to meet Asian and 1.2 per cent as mixed.
though he says he hasn’t for “gold” aren’t even laid out yet. “If you don’t see people like you
“Scientists think they’re too experienced that personally. “The scheme doesn’t have any in a system, you are less likely to
smart to be racist and so “There is gatekeeping.” incentive, it’s more of a marketing choose that path,” says Hussain.
put up a shield whenever One fundamental problem is a tool. Ethnicity problems are where
people talk about it” lack of incentives for universities gender problems were 20 years
to do better. Equality on funding ago,” says Hussain. Outright racism
there might be so few people from for female researchers in the UK The lack of ethnic minorities Then there is the problem of
a particular ethnic minority got a huge boost in 2011 when Sally among staff in the universities of outright racism in academia, says
applying to a certain funding Davies, then the UK government’s many countries, and the resulting Sulu. A freedom of information
body – a single British Bangladeshi chief medical adviser, linked loss of the mentoring and role request last year found that only
researcher, for example – that funding from the National modelling they could have 37 per cent of formal complaints
they would be identifiable. Institute for Health Research to provided, is a big deterrent for on racism at UK universities in
“They have been using this universities achieving a specific BAME students continuing five previous years were upheld.
argument for decades now. But standard for a gender equality a career in science. The problem There are many other barriers
if you don’t break things down scheme. Universities fell over is worst at the top. that add up. One is micro-
to a granular level, we will never themselves to meet the standard. Of the 540 people across UK aggressions, where people are
know if there is a problem,” says treated differently just because
Tanvir Hussain at the University of their ethnicity. Sulu gives the
of Nottingham in the UK, who How do we address the problem? personal example that visitors
is also a member of TIGERS. at University College London
A workaround would be to Paulette Williams at Leading 26 per cent of roles it filled in are often surprised to see him
publish most of the breakdown Routes, an initiative to help those sectors in the UK in the in his department.
apart from where issues of more black students into UK past year went to people who Some students, such as
identification and disclosure arose universities, has said there is no self-identify as black, Asian or Akinbosede, are cynical about
because numbers were so low, quick fix to solve the problem of minority ethnic. But only 10.5 per universities’ efforts on racism.
says Sulu. In such cases, the figures racism in universities and science. cent of the scientific workforce “Universities want the perception
could be withheld and the reason In a 2019 report, she and her is BAME, figures from the UK of anti-racism, without actually
publicly acknowledged, he says. colleagues offered actions such Royal Society reveal. Tying doing any anti-racism,” he says.
Previously, the national figures as better data collection and more funding to institutions being more A spokesperson for
also masked how some research diverse interview panels, amid inclusive would be another route. representative body Universities
funders are more regressive than the more seismic change needed. Change must also come from UK says: “Universities have a vital
others. More than half a year after Another idea is name-blind researchers educating themselves role to promote a safe and inclusive
promising to make more detailed applications. While Michael Sulu on the barriers that some people environment in which students
data available, UKRI told New at University College London says face due to the colour of their and staff of all backgrounds and
Scientist that it plans to publish they are “borderline impossible” skin, says Tanvir Hussain at the ethnicities can flourish. The sector
a council-by-council breakdown in academia because of the need University of Nottingham, UK. is clear that there is no place for
on 24 June. to show publications, they may “One of the key problems we have racism on a university campus,
The group says it is also have a role in hiring for careers in academia is we’ve fostered the nor anywhere else.”
undertaking an in-depth analysis in science, engineering, maths, idea it’s a true meritocracy. But Akinbosede, like Osman, is
on ethnicity to underpin new medicine and technology. it’s not,” he says. “The only way still actively working to make
action on inequalities. Kate Glazebrook at Applied, we can challenge that narrative his university more welcoming
For BAME academics in the UK, a recruitment platform that tries is letting people be aware and to BAME students. He says: “It feels
the obstacles begin even before to remove hiring bias, found that read more widely about it.” like I am doing two PhDs: one in
they have to start dealing with biochemistry and one in race.” ❚
News
Palaeontology Exoplanets
them lost it during geological out when they originated might might create friction that dissipates
history,” says Delarue. be to estimate when the key heat inside the planet. Modelling
He says the appendages genes responsible for mobility will be needed to understand this
could be the earliest evidence first evolved, says Bosak. ❚ further, says Thorngren. ❚
News In brief
Humans
Really brief
Did Stone Age rulers in
Ireland practice incest?
A MAN buried at the heart of
the 5000-year-old Newgrange
passage tomb in Ireland was
born from an incestuous union,
EIJIRO MIYAKO
DNA sequencing has revealed.
Daniel Bradley and Lara
Cassidy at Trinity College Dublin
sequenced the genome of remains
found in a burial chamber in the Soap bubbles can
200,000-tonne tomb. “People pollinate flowers
have said it is the Irish equivalent
of the pyramids,” says Bradley. “It Mix pollen grains with soap
required a lot of muscle to build.” and load the blend into a
The man’s parents were either bubble gun, and you have
brother and sister or parent and a way to fertilise flowers
offspring (Nature, doi.org/dzr5). without bees, whose
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Signal Boost
Welcome to our Signal Boost project. In these difficult times, we are offering
charitable organisations the chance to take out a page in New Scientist, free
of charge, so that they can get their message out to a global audience.
Today, a message from Greenpeace
Views
Letters Culture Culture Aperture
Can we create a computer Sci-fi’s suggestions How Disney became The caterpillar that
simulation that includes for how to avoid a a massive research wears its old heads as
conscious entities? p22 techno-apocalypse p24 organisation p25 an elaborate hat p26
Columnist
I
Graham Lawton is a staff WANTED to join the recent Much has been made of the link finds that people who are Hispanic,
writer at New Scientist and Black Lives Matter protests between today’s racial injustices African American or from other
author of This Book Could Save in London, but I also didn’t and historical slavery. According minority ethnic groups are more
Your Life. You can follow him want to be in close proximity to to Elizabeth Yeampierre, co-chair concerned than people who are
@grahamlawton thousands of other people for of the Climate Justice Alliance in white about environmental issues.
hours on end. My fear of catching Washington DC, environmental BLM rests on the simple idea
the coronavirus won out and so I injustices also began with slavery. that if the people who are affected
demoted myself to social justice The rapacious exploitation of by racial injustice come together
warrior (armchair division) and humans enabled the rapacious and say “no more”, the pressure
watched on TV. exploitation of the environment, to change will be irresistible.
The protests are principally a and just as the legacy of slavery Environmental justice works in
fight for social justice. But I also endures in racism, so it endures in a similar way. If the people most
view them through another lens. affected by environmental
Black Lives Matter may not look “Black Lives Matter degradation fight back, it becomes
Graham’s week
like an environmental movement, may not look like harder for destructive industries
but I think deep down it is one, an environmental to make and conceal their messes
What I’m reading too. If – when – it achieves its in places where the wealthy and
movement, but I
London’s Street Trees: A objectives, the world will not only powerful elites don’t go.
field guide to the urban be more socially just, but more think deep down That is the direct line between
forest by Paul Wood. sustainable, as well. it is one, too” BLM and the battle for the
Feeding my obsession The causes of social and environment. They are one and
with the city’s wildlife environmental justice first crossed the economic model that regards the same. You could also bundle in
paths in the US in the 1970s when the environment as a resource to the health disparities that have led
What I’m watching activists from both camps realised be plundered, not preserved. to covid-19’s disproportionate
Season 2 of the deadpan that they were fighting many of Since the 1970s, environmental death toll on poor and minority
vampire comedy What the same battles. Pollution and injustices have only widened. The ethnic communities.
We Do in the Shadows other forms of environmental effects of climate change are now BLM activist Zellie Imani
degradation disproportionately kicking in, and guess what: they acknowledged that he and his
What I’m working on affected certain sections of society: disproportionately affect people fellow protesters were taking
Yet more covid-19 poorer people, working class who are unable to escape from health risks – both personal and
coverage people, people of colour, Native extreme weather events. Consider public – by assembling in large
Americans and immigrants. how Hurricane Katrina laid crowds, but said that this historic
Their neighbourhoods also lacked waste to the poorer districts of cause was more important. “Going
green space and access to nature. New Orleans in 2005, and how outside may kill us because of the
It isn’t hard to fathom why Hurricane Maria did the same pandemic, but going outside as a
this link exists. It is another in Puerto Rico in 2017. Black person in America has been
manifestation of the unequal This disparity hasn’t gone killing us for over 400 years,” he
distribution of wealth and power unnoticed in the communities told Sky News.
in society. Rich people can afford it affects. Concern about the The pandemic has been
to buy their way out of degraded environment is often dismissed widely flagged as a chance to
This column appears neighbourhoods, and have as a self-indulgent pursuit for build a more sustainable society.
monthly. Up next week: the political clout to resist the wealthier (i.e. white) people. But It is also an opportunity to build
Annalee Newitz incursion of polluting industries. it isn’t: polling in the US regularly a fairer one, too. ❚
covid-19 can cause serious illness On the trail of the desire, in this lockdown hell,
Editor’s pick and even death, the regulatory to experience vigilance and
missing dark matter
bodies wouldn’t be unreasonable amazement.
We won’t survive long 6 June, p 30
in taking a cautious approach. I They cite as an example being
enough to simulate reality would like to suggest a possible From Stephen Graham, able to watch the daily life of a
6 June way to reduce this dilemma. Ottery St Mary, Devon, UK family of falcons unfold through a
From Mike McGrath, Perhaps plasma from vaccinated Your fascinating articles about dark webcam, and say that this reflects
Leeds, West Yorkshire, UK subjects could be given to people matter, in particular “Have we got a need to vicariously experience
In “Is reality a simulation?” by with mild to moderate covid-19. the universe right?” by Jim Peebles, natural processes over time.
Nick Bostrom, republished as an If these people show a reduction prompt me to suggest that we I am growing borlotti beans
extract from your Essential Guide: in the development of serious should consider more closely how in my little front garden, and
The Nature of Reality, he ponders illness, this may indicate that the much mass has been drawn into it occurred to me as I read the
the question posed in the headline. antibodies from the vaccinated black holes since their inception article that this is exactly what
To answer yes, it would person’s plasma are effective and what has happened to it. I am doing: watching through
have to be possible to create a in reducing disease severity. Some scientists suspect that my front window as they grow,
computer simulation that includes Not only would the ethical dark matter is at the centres of night and day, the fragile tendrils
self-conscious entities. It may be difficulties for the regulatory galaxies, where some or most of spiralling up their canes to the sky.
possible, if extraordinarily difficult, bodies be reduced, but the the black holes seem to be. Could The only difference is that
to replicate the physical matrix shortage of plasma from it be that the suggestion that dark Newitz doesn’t (I hope!) look
of the brain, but achieving the recovered patients would matter came into being about forward to drying, storing, then
emergent quality of consciousness also potentially be alleviated: 6 billion years ago defines the cooking and eating the falcons
from this seems very unlikely. a win-win situation. point at which black holes became in a stew later in the year.
Bostrom considers various significant enough in size or mass
propositions that might answer the to exert the effect on the universe From Ian Simmons,
There are other ways
simulation question. The first is that that we are trying to explain by Thorpe Bay, Essex, UK
“almost all civilisations at our level to keep shipping safe postulating “dark matter”. The oddly satisfying videos that
of development become extinct 13 June, p 19 Can I have my PhD now please? Newitz enjoys brought to mind
before becoming technologically From Jørn Hovmand Larsen, videos that are said to provoke
mature”, which would rule out a Greve, Denmark From Julian Higman, an autonomous sensory median
simulation if true. I would say this In your online story about Wantage, Oxfordshire, UK response (ASMR).
is likely to be correct, given our spoofing the Automatic Peebles is correct to say that The audio and tactile triggers
trashing of our essential biosphere. Identification System (AIS) of physics is incomplete. It probably in ASMR footage that apparently
This would mean, of course, ships, you state: “There haven’t always will be. So, have we got the give some people a pleasurable
that Bostrum’s final proposition, been any known accidents due to universe right? sensation leave me cold, but I
“You are almost certainly living in the spoofing, but ships rely on AIS Well, the short answer must do get something close to that
a computer simulation”, is almost to avoid collisions, so there is the be that we don’t know. But there from looking at things like
certainly not true. potential for major disaster.” are good reasons for suspecting robots making very precise
As a merchant ship captain, that we haven’t, and that the big movements and repetitive
❚ The editor writes I can say that AIS, which includes bang theory is wrong. As we get production line processes.
Essential Guide: The Nature of GPS data, has without doubt more and more telescopes of I thought it was just me, but
Reality, a compilation of the best increased safety at sea because varying kinds up into orbit, not it seems that Newitz and others
New Scientist writing on this ships are transmitting identity just around Earth but around experience something similar.
subject, is available now and destination. This resolves a lot the sun too, the picture will
of potential problems. However, become clearer.
To train a lie-detecting AI,
AIS isn’t a recognised system for
Is there a route to make just feed it some politics
collision avoidance – radar and
vaccine trials safer? Newitz’s falcons are Letters, 6 June
visual observation usually are.
6 June, p 10 Yes, GPS can be spoofed, and this my borlotti beans From Sam Edge,
From William Cole, can create issues if you rely solely 6 June, p 21 Ringwood, Hampshire, UK
Bishop’s Stortford, Hertfordshire, UK on GPS. But with the proliferation From David Aldred, Dwight Hines suggests that
You report that there are already of satellite navigation systems Elloughton, East Yorkshire, UK court transcripts could be a
26,000 potential volunteers besides GPS, it will become more Annalee Newitz wrote source of training material
willing to take part in a “human difficult to spoof ship locations. interestingly about our general for a linguistically based
challenge” trial for a covid-19 lie-detection algorithm.
vaccine, in which they would I offer the pronouncements
be exposed to the virus post- Want to get in touch? of our top politicians and
vaccination to test its efficacy. Send letters to letters@newscientist.com; their aides with respect to the
However, as indicated, ethical see terms at newscientist.com/letters pandemic and to climate change
concerns are likely to prevent Letters sent to New Scientist, 25 Bedford Street, as a much richer seam of data
or delay such trials. Given that London WC2E 9ES will be delayed to mine for this purpose. ❚
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Mad hatterpillar
Gege Li
Body
consciousness
When it comes to consciousness, your brain
isn’t the whole story, finds Laura Spinney
P
ARTS of Ann Arbor bring The Truman others to a surprising conclusion: that the
Show to mind, with their wood-frame body helps to generate our sense of self and
houses and white picket fences. Home is a key part of consciousness. This idea has
to the University of Michigan, the city oozes practical implications in assessing people
middle-class prosperity and security. So, who show little sign of consciousness. It may
while doing research there a decade ago, also force us to reconsider where we draw the
Sarah Garfinkel was shocked to discover line between life and death, and provide a
that young veterans of wars in Iraq and new insight into how consciousness evolved.
Afghanistan felt terrified even in Ann Arbor. It has long been known that our internal
“It broke my heart,” she says. And it changed organs have lives of their own. They generate
the course of her career. electrical activity, which is conveyed by
Garfinkel was in Michigan to study the neurons to the brain. As a result, signals from
brain circuitry involved in persistent fear. your heartbeat, your breathing, the slow,
But working with traumatised veterans, she regular pulses of your stomach and the state
realised two things. First, a safe environment of your muscles are all represented in the
didn’t help them feel less fearful. And second, brain’s electrical activity. The brain, in turn,
their fear was physical as well as mental: regulates these functions. In other words,
their hearts were constantly racing, their there is a neuronal loop in which nerve cells
pupils dilated, their palms sweaty. “It seemed carry information from the organs up to the
to me that what their bodies were doing was brain, and commands down to the organs.
meaningful, but I was just scanning their However, in the 20th century,
brains,” she says. So she set out to understand neuroscientists tended to ignore the body.
the body-mind connection. They associated mental life exclusively
Garfinkel, now at the University of Sussex, with the brain – an approach epitomised
UK, discovered that our bodies have more by the “brain in a vat” thought experiment,
influence over our minds than you might in which a disembodied brain continues to
imagine. “Our thoughts, feelings and have normal conscious experiences.
behaviours are shaped in part by the internal Things began to change at the turn of
signals that arise from our body,” she says. this century, when neuroscientist Antonio
But it goes beyond that. It is leading her and Damasio at the University of Southern >
play a big role in that continuity of self.” biggest HEP at the moment of choice gave
Catherine Tallon-Baudry, a neuroscientist answers that were most in line with their
at the Ecole Normale Supérieure in Paris, original ratings. Their choices were truest
France, has a different conception of how to themselves when their brains were
the body contributes to self-consciousness. listening most closely to their hearts.
The brain is constantly bombarded by signals Blanke’s notion of a bodily self and Tallon-
from inside and outside the body and as a Can a robot ever be Baudry’s notion of bodily consciousness may
result of its own cognitive processes. The conscious without a not be too far apart. Indeed, they can imagine
signals are processed by different brain heart, lungs and gut? hitting on an overarching model of the
circuits. She thinks that rhythmic signals embodied self that reconciles their findings.
from the organs impose a unified frame consciousness, but says there is no need to But how does Garfinkel’s research fit in?
of reference on the brain. This allows us to conclude that the self is involved. To address
perceive all that incoming information from this issue, Tallon-Baudry and her group
the perspective of a single, subjective “I”. devised another study. This time, they homed Emotional me
“I think of consciousness as a property that is in on the distinction between “I” and “me”. She has been exploring two connected
generated by the brain once it has integrated Tallon-Baudry says “I” captures the most ideas: that bodily signals influence emotions
information from the whole organism,” she basic aspect of self – the aspect that comes and that emotions shape our sense of self
says. And a series of experiments supports before thought, the unified entity that does through memory and learning. Working
her contention, she believes. the thinking. It is fundamentally different with people with autism, she has concluded
In 2014, Tallon-Baudry and Park, who from the kind of reflection about “me” that the problems they often encounter
worked in her lab before he moved to that implies monitoring different bodily relating to others stem from their brains
Blanke’s, began by exploring how the HEP functions without that sense of unity. being overwhelmed with the visceral inputs
might influence our conscious experience of To see if they could show that the brain associated with their own and others’
things. They asked people to fix their gaze on treats those two concepts differently too, emotion. Building on the idea of an
a central point and to say whether they could Tallon-Baudry’s team asked people who were overactive body-brain axis, Garfinkel’s
see a faint ring around that point. The bigger having their brain scanned to fixate on a point research has now come right back to what
a person’s HEP just before showing them the and then let their mind wander. Every now haunted those traumatised war veterans:
ring, the more likely they were to perceive it. and then, they were interrupted and asked fear. In her most recent study, she has
“The heartbeat behaves like an extra piece whether – at that precise moment – they adapted a classic psychology paradigm
of visual information,” says Tallon-Baudry. were thinking about “me” or “I”, which they called fear conditioning, in which volunteers
It also provides the intrinsic “mineness” of had been trained to recognise. Depending learn to associate neutral stimuli with
the conscious experience. “In the person’s on which they reported, the HEP occurred negative consequences. She measured
response – ‘I saw something’ – there is that in different parts of the brain: a region near people’s heartbeats and their skin’s electrical
element of ‘I’,” she says. “We shouldn’t ignore the front for “me” thoughts and one further conductivity, which increases when we feel
that element of ‘I’ in perception.” back for “I” thoughts. This showed for the fearful. Her volunteers showed more fear
Blanke sees this study as a beautiful first time that the brain does indeed discern when stimuli were presented as their heart
demonstration of the threshold of between the two concepts. was contracting than when it was relaxing. >
Signal Boost
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Features
The enduring
grip of covid-19
Contrary to medical expectation, many people with
covid-19 are still experiencing symptoms weeks or even
months later. Linda Geddes investigates what’s going on
W
ITHIN 24 hours of asking an online in two months. Others reported fatigue, were dealing with a respiratory infection that
covid-19 support group if anyone headaches, tingling fingertips and brain fog. had symptoms similar to flu, and that while a
had been experiencing prolonged As the months tick by since the start of the minority of people would develop pneumonia
or unusual symptoms, I had been messaged coronavirus pandemic and we learn more and need breathing support, most would
by 140 people. The list was mind-boggling and about covid-19, it is becoming increasingly experience a mild illness characterised
deeply upsetting. “I feel like I’m in the middle evident that even mild cases can have by a cough, fever and shortness of breath,
of a waking nightmare,” said Zoe Wall, who distressing and long-lasting effects. “There’s which would be over in a couple of weeks.
was previously fit and healthy. Two months clearly something going on here. It is not Some of the first clues that the coronavirus
after developing covid-19-like symptoms, their imagination or hypochondria. It doesn’t behind covid-19, SARS-CoV-2, might trigger
she was still experiencing chest pains and even seem to be linked to how severely they more widespread disease began to emerge
“fatigue beyond description”. had the disease, as far as I can see,” says in February, when the outbreak in the
Harry’s symptoms started with a terrible Danny Altmann, an immunologist at Chinese city of Wuhan was at its peak and
headache and itchy body, followed by Imperial College London. All this means we doctors in the Lombardy region of Italy
shortness of breath. He was still experiencing need to rethink how we diagnose and treat were also experiencing a surge in cases.
breathing difficulties, chest pain, numbness covid-19. The long list of symptoms also As their emergency department colleagues
in his arm and bloating 10 weeks later. Jenn seems to suggest there might even be several fell sick, doctors like Sebastiano Recalcati,
had had no sense of smell or taste since subtypes of the disease, which could help us a dermatologist at Alessandro Manzoni
testing positive for covid-19 on 31 March. predict which cases will become serious. Hospital in Lecco, Italy, began taking over
Abbi had minimal respiratory symptoms, When the pandemic was announced in the care of those hospitalised with covid-19.
but very bad gastric ones and lost 19 kilograms early March, the prevailing view was that we He noticed skin problems in around 10 per
ROBERTO CIGNA
cent of the covid-19 patients he encountered. That was just the start. By mid-March, the
Some symptoms, like a flat red rash on virus had spread across Europe and many
people’s torsos, could have had other causes “Hardly countries were announcing lockdowns.
besides the virus, but others were more As epidemiologist Tim Spector packed up
specific: some patients developed small anyone’s his lab at King’s College London, he pondered
blisters on their torso or around their how he might continue his research, on
mouth – similar to those seen in chickenpox, symptoms are the health differences between twins,
except that they weren’t itchy. from home. Together with the technology
Since then, he and others have the same the company Zoe, Spector developed an app
documented other skin symptoms, to allow the twins in his study – and maybe
including a reddish-purple rash, whole way the general population – to log and track any
caused by tiny clots in blood vessels, potential covid-19 symptoms they developed,
and chilblain-like lesions on the toes. through” so they could be monitored over time.
Unlike the earlier rashes and blisters that The Covid Symptom Tracker app launched
Recalcati spotted, which seem to strike at on 23 March – the start of the UK’s own
the time of infection, these additional lockdown. Within 36 hours, it had been
symptoms occur several weeks later. downloaded by 1 million people, and by
“We think they may be a delayed immune 29 March they had 1.5 million users, of whom
response, whereas the other types of rash 1702 reported having been tested for covid-19.
may be a direct viral response,” he says. “That’s when we started to see this lack of >
smell coming up as the top feature, present in The list of unexpected symptoms doesn’t
60 per cent of people who had positive tests,” stop there. Other covid-19-associated
says Spector. This is higher than fever or
cough, in predictive terms, he says, because
“The extreme gastrointestinal problems, such as diarrhoea,
nausea and vomiting, have been reported
some of those who tested negative for the
coronavirus also had fever or cough. Studies
fatigue is like by researchers in California and Hong Kong,
and many doctors are reporting neurological
in China and Italy have also found loss of
smell and taste to be quite common in people
being hit over symptoms ranging from headaches and
dizziness to seizures and hallucinations.
with covid-19. As a result, loss of smell and
taste are now recognised as a key symptom
the head with There have also been reports of covid-19
patients being discharged from hospital,
by several health bodies including the NHS.
Other predictors currently being
a cricket bat” only to return several weeks later with a deep
vein thrombosis or blood clot on the lung,
investigated are severe muscle pain, which says James O’Donnell, director of the Irish
seems to differ from the general aches and Centre for Vascular Biology in Dublin.
pains you get with the flu – “it can be very Some relatively young and healthy people
acute and very painful”, says Spector – and with mild covid-19 are having heart attacks
loss of appetite, which may be connected or strokes with unusual features. “The strokes
to the loss of taste or smell. Spector seem to involve multiple different parts of
himself lost 3 kilograms within a week the brain, and some of them are occurring
of developing relatively mild covid-19. and progressing despite patients being on
standard blood thinners,” says O’Donnell. working with coronaviruses since the early immune cells encounter an invader, they
“This started off as a respiratory illness, but 90s, including the one that causes MERS. release signalling molecules called cytokines
within the space of a couple of months we’ve “Nothing that we are seeing with this to rally further immune help. Some of these
now got this kind of multi-system phenotype coronavirus has not been seen with other cross into the brain and trigger further
that we don’t really understand very well.” coronaviruses,” he says. “We know from cytokine secretion and inflammation.
Then there is the extreme fatigue. Paul animal studies that the same coronavirus can “People who get infected with this new
Garner, who had to stop working after cause many different types of clinical disease. coronavirus often have this hyper-intense
coming down with covid-19 in mid-March, We also know from our experience with SARS inflammatory reaction and being in such an
likens the feeling to being hit over the head and MERS that some people are fine, whereas inflamed state will have a negative impact on
with a cricket bat. “Calling it post-viral fatigue others are worse off.” brain health,” says Bullmore. Specifically, it
isn’t helpful because the fatigue has been can damage nerve cells in areas of the brain
there from day one, and runs alongside responsible for emotion regulation.
some quite nasty, life-threatening Immune reset Inflammation may persist long after
conditions,” he says. “It also implies we The same applies to longer-term health SARS-CoV-2 has been cleared from the body.
know what’s happening and that the virus issues. Around 28 per cent of people who had “The healthy response to this virus is to
has gone – but we don’t know any of this stuff SARS were still experiencing impaired lung have massive immune cell activation,” says
really.” Now, three months later, he can only function 18 months after SARS symptoms Altmann. “It would not at all surprise me if
work for 20 minutes at a time before needing started, affecting their ability to exercise and that could slightly reset the set point of your
to lie down, and will soon return to work for their overall quality of life. And a recent meta- immune response in a slightly pathological
an hour a day. Garner says his symptoms are analysis suggested that depression, anxiety, and chronic way.”
the same as chronic fatigue syndrome, with insomnia and fatigue were all found in about Exhaustion could also be linked to vascular
one difference – CFS is defined as not having 10 to 20 per cent of patients in the months symptoms, such as blood clots, which may be
a cause. “This clearly has a cause,” he says. following recovery from SARS. “If covid-19 caused by the immune system or by the virus
Garner speaks with authority. A professor plays out anything like SARS and MERS, there infiltrating the cells that line blood vessels.
of infectious diseases at Liverpool School of will be quite a bit of this longer-term mental Microclots in the lungs could reduce oxygen
Tropical Medicine, he has experienced many illnesses and fatigue,” says Ed Bullmore, a supply by restricting the movement of
of the diseases he studies first-hand. The only neuroscientist at the University of oxygenated blood through the lungs. “We
one that is vaguely comparable, he says, is Cambridge and author of The Inflamed Mind. think we’ve probably got a positive feedback
dengue – a mosquito-borne illness This isn’t just about the psychological loop going on where we’ve got pneumonia
characterised by bouts of exhaustion long trauma of being seriously ill. According to followed by micro-clots in the lungs, followed
after the virus clears. “The weird thing with Bullmore, it is a product of our immune by low blood oxygen, and those things go
covid-19 is how it sort of goes away, and you system’s response to infection. When our round and round in a circle,” says O’Donnell. >
feel a bit muggy and a little bit drained and
then you feel a bit better and then, whack, it
comes at you again from another direction.”
It is this persistent nature of some cases Public health
of covid-19 that troubles many of those who messaging in
contacted me via the online support group. England and Wales
A big frustration is the sense that because on symptoms
they don’t require hospital treatment, their doesn’t fit with
symptoms aren’t taken seriously, and they the way many
are largely left to fend for themselves. “We people experience
keep being dismissed as anxious people who covid-19
haven’t yet given their bodies time to heal,”
said Wall. This lack of medical support really
STU FORSTER/GETTY IMAGES
It is unclear whether microclots are occurring how long these can be expected to last. Here,
in people with mild cases of covid-19, but if Spector has some insights. Having now
the body isn’t getting enough oxygen, this tracked some 2000 people with positive tests,
could cause many of the long-term symptoms he has found that the median duration of
people are experiencing, such as shortness symptoms was 10 days, but they sometimes
of breath, headache and exhaustion. endured for extended periods. One in
ISABEL INFANTES/EMPICS ENTERTAINMENT/PA IMAGES
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Episode 22 out Friday 26 June
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Features
PAUL WILLIAMS/NATURE PL
W
EAVING through the sweaty particles – things like dust, pollen, sea salt and
tangles of a Panamanian forest, smoke – to form droplets and clouds. As they
Steve Yanoviak is hunting a rise and cool further, these droplets turn to ice.
killer. Its prey isn’t the monkeys, bats or Lighter ice particles rise to the top of the cloud
multicoloured birds that cram the branches, and tend to lose electrons, becoming
but the foundations of the forest itself – its positively charged, while heavier falling
trees. Each day, this killer strikes thousands particles tend to gain electrons and become
of times around the world, but leaves no negatively charged. The electric potential
evidence behind. “Tropical trees die standing. between the two mounts until giant sparks
They bear no scars,” says Yanoviak. form within the cloud to restore balance.
Catching it in the act takes monumental When sparks really fly, however, is when
effort. That’s because the likely culprit isn’t the negatively charged base of the cloud
a living organism, but instead a familiar starts inducing a positive charge on nearby
force of nature: lightning. bits of ground, concentrating it in protruding
Yanoviak, an ecologist at the University objects such as trees, spires or people. When
of Louisville, Kentucky, is just one of many those two oppositely charged areas are close
researchers around the globe confronting enough, a lightning bolt can make contact
the profound, underappreciated effects that with the ground.
lightning has on the natural world. It ignites For most of us, the destructive potential of a
wildfires that reset ecosystems. It can boost lightning strike is best marvelled at through a
greenhouse gases, and unleashes other window. Though the data is patchy, strikes are
pollutants in an instant. And in the tropics, estimated to kill up to 24,000 people a year
it is the grim reaper that singles out the globally and injure 10 times that number. The
most magnificent of ancient forest trees effects are disproportionately concentrated
for destruction. in lower income countries, where often
What’s more, lightning is probably “there is absolutely nowhere for anybody
on the increase, and that’s because of us. to go”, says Ron Holle, co-author of the book
Climate change seems to be driving up Reducing Lightning Injuries Worldwide. In
the frequency of strikes, while population Bangladesh, for example, lightning killed
growth and changes in land use are 64 people within just four days in 2016. In a
exacerbating their effects. The toll on recent study, Holle highlighted how lightning
both the human and natural spheres strikes in the country peak in April and May,
has sparked a new urgency in getting to exactly the time of year when farmers have
grips with this everyday phenomenon. to harvest their rice.
It all begins harmlessly enough, with But the effects of lightning on human
moisture-laden hot air that rises from the health and well-being can be more insidious.
warm surface of Earth. As it cools, water In a few microseconds, it can heat a sliver of
vapour condenses around microscopic air to 30,000 °C, leading to rapid chemical >
Unlucky strikes
One of lightning’s most profound impacts
on natural ecosystems, however, might have
been overlooked had ecologist Lucy Rowland
at the University of Exeter, UK, not had a
spooky encounter in the Amazon rainforest.
She had poked needles into a few trees to test
the flow of sap up and down their trunks,
before retiring to the safety of her camp.
Then, lightning struck. When Rowland
returned, her instruments were smouldering
and ruined, but the tree showed no signs of
damage itself. A few months later, however,
it and its neighbours were dead.
EVAN GORA
This is odd. When lightning strikes a tree
in temperate climes, the damage is generally
obvious. Electrical current is thought to
run down the moist layer inside the bark, In the rainforests
which expands explosively under the high of Barro Colorado
temperatures, sending chunks of bark flying. Island, Panama,
No one knows why tropical trees escape this lightning causes half
fate, though it is possible that they somehow of all large tree deaths
distribute the current differently.
This silent destruction got Rowland’s
colleague Tim Hill, also at the University of
Exeter, thinking. With a back-of-the-envelope
calculation using satellite lightning data and
tree censuses, he concluded that, if every
tree had an equal chance of being struck,
lightning would be insignificant for the fate
of the forest because most trees are small and
unimportant. But if the biggest trees were to
be struck more often, says Hill, that would
change everything. Larger, older trees
NASA
1,000,000
100,000
10,000
1000
The Geostationary
Lightning Mapper
100
is helping build a
picture of lightning’s
true frequency in
the US
are keystone structures of the forest: they that die in the forest, what fraction are dying they tally with the data we have – and
are biodiversity hotspots, bug hotels and from lightning, I might have said maybe 5 per this could indicate potentially severe
generally play a major part in its survival cent,” says Yanoviak. “We’re now beginning consequences, not least for forest ecosystems.
and well-being. They also disproportionately to understand that lightning is far more Sander Veraverbeke at Vrije University in
contribute to the storage of water and carbon important than anyone expected.” Amsterdam, the Netherlands, has been
dioxide. “The top few per cent can store Our basic ignorance about lightning runs studying the incidence of lightning across
50 to 60 per cent of the carbon,” says Hill. deep. We don’t even know how much of it the spruce and pine forests of northern
Figuring out whether they are is happening globally, because it is mostly Canada and Alaska, and has found that
preferentially struck by lightning could monitored by local ground-based systems. lightning-ignited fires in these boreal
therefore be of huge consequence. “It’s a “Tying them together in some kind of a forests have risen relentlessly by 2 to
potentially important effect that no one patchwork is very difficult,” says Jochen 4 per cent a year for the past 40 years.
really thinks about,” says Hill. That is hardly Grandell at the European Organisation for In unpublished work, Veraverbeke has
surprising. Determining lightning’s impact the Exploitation of Meteorological Satellites. collaborated with Romps and others and
on tropical trees turns out to be incredibly Our best estimate is that there are about found a similar trend for the entire ring
difficult when the killer strikes randomly 1.4 billion flashes worldwide each year. But of boreal forests – in Canada, Alaska,
and unpredictably, when there are hundreds as the planet heats up and the atmospheric Scandinavia and Siberia – as well as for the
of thousands of potential victims and when convection necessary to create lightning Arctic. “We expect quite significant increases
there is no sign of the kill for weeks. increases, there are good indications that in lightning – not only more, but it moves
Hill is now equipping 20,000 tropical these numbers are on the rise. further north,” he says.
forest trees in Nigeria and Ghana with coils In 2014, David Romps at the University of In these forests, as in warmer climes,
of wire. When lightning strikes, its current California, Berkeley caused a stir with a new lightning strikes and attendant wildfires
induces a magnetic field in the coil, which clear patches to allow new growth. They
is instantly logged to identify exactly which are essential for the reproduction of some
tree was struck. “Our best estimate species, such as black spruce. But the more
Yanoviak is taking a different approach. wood that burns, the more carbon is
Since 1996, when lightning struck a tree is that 1.4 billion released – and more clear patches means
terrifyingly close to him during a storm over
a forest on Barro Colorado Island in Panama,
lightning flashes more sunshine can penetrate the permafrost.
That is troubling because of the huge amount
he has been working to catch it in the act.
Working together with his colleague Evan
occur each year” of trapped carbon that could be released into
the atmosphere as the permafrost melts.
Gora, also at the University of Louisville, he It could even be a damaging feedback loop,
has now installed a system of surveillance model that predicted lightning would increase says Veraverbeke. “Because of warming, you
cameras above the Panamanian forest as the planet warmed. It was tricky work: have more lightning. Because of lightning,
canopy, as well as meters on the ground large-scale global climate models operate at you have more fire. Because of fire, you have
below that can detect an electrical surge. such low resolution that they can’t portray more emissions. Because of emissions, you
Algorithms triangulate this data so Gora the behaviour of small and fickle phenomena have higher temperatures.”
knows where to search, with the help of a such as clouds and thunderstorms. Not everyone agrees that climate change
drone, for signs of tree death by lightning. The assumptions he had to make led to is driving up the incidence of lightning. Last
They are still collecting data, but a model that even Romps calls naive, but it year, Declan Finney at the University of Leeds,
so far their results indicate that, to their correlates with the lightning incidence in UK, argued that Romps’s model failed to
astonishment, half of the deaths of large modern records. It predicts that, for every consider how much evaporated water actually
tropical trees are down to lightning – not least 1°C rise in global temperature, there will turns to ice in clouds – an essential ingredient
because it seems a single strike can bounce be a 12 per cent hike in lightning incidence for lightning. His own model, which took
off one tree to affect an average of five others. over the US. Projecting forward to the end this effect into account, predicted a fall in
Assuming that other tropical forests respond of the century, that means business-as-usual lightning incidence. Late last year, Romps
in a similar way, lightning might kill about greenhouse gas emissions would lead to a published a second paper that played with
190 million tropical trees each year globally, 50 per cent increase in lightning strikes in his and Finney’s approaches. It concluded that
and damage half a billion others. the country. they both pointed to an increase in lightning
“If you had asked me, of all the large trees These numbers may sound dramatic, but in the US, while disagreeing with each >
Stormy future
These records do show increases in
thunderstorms over the past century in to plant, says Guy Midgley at Stellenbosch Farmers ploughing
places ranging from south-east Brazil to the University in South Africa. He is still upset flat, watery terrain
UK and from Japan to Alaska. Since 1970, “we about fatal fires that broke out in pine and are very vulnerable
see a dramatic rise”, says Price, adding that eucalyptus plantations after lightning strikes to lightning strikes
the trend goes on for too long to be the result in the country’s Western Cape in 2017. These
of natural climate cycles, such as El Niño. He non-native plantations and escaped trees lightning storms on the east and west coasts
then found a correlation between a warming growing in surrounding grasslands have was transformed by the launch of the
climate across the African continent and increased the fuel load. The combination Geostationary Lightning Mapper satellite
the number and size of thunderstorms – of increasing drought, fire-prone species and in 2016. Europe aims to launch an even more
a thought-provoking 40 per cent increase more frequent lightning raises increasingly ambitious version, the Lightning Imager, in
for every 1°C rise. “It’s difficult to say that important questions about the sense of such 2022. Grandell predicts that in a decade, such
that’s causing the increase, but they are tree-planting schemes, he says. He isn’t alone. information will trickle through to all. People
fairly well-correlated,” says Price. Researchers recently concluded that such fishing on Lake Victoria in East Africa, for
If the correlation holds, the consequences climate-related changes were risky enough for example, will be warned by SMS message
could be severe for tropical forests, with the plantations in California that the land would that lightning is sweeping in and that they
death rate of the biggest trees increasing by absorb more carbon if it was left as grassland. should return to the shore.
a fifth by the end of the century. That is likely If lightning is really set to strike more, Meanwhile, the work to establish the
to have repercussions. Most obviously, the one key to staving off the worst effects on consequences for the ecosystems we rely on,
death and decay of these forest giants will the natural world, as well as protecting in Panama and elsewhere, continues. The true
release carbon that has been locked away human life and property, will be an improved complexity and power of an awesome natural
in them over decades into the atmosphere, ability to spot lightning coming. Big storms phenomenon is only now being revealed. ❚
changing our climate models in ways that can be forecast days ahead, but smaller ones
could take years to comprehend. can whip up, unnoticed, in a few hours Aisling Irwin is a freelance writer
In more recently planted forests, an anywhere when the conditions are right. based in Oxfordshire, UK
increase in lightning needs to be factored Fortunately, the tech is now arriving.
in to decisions about where, how and what In the US, the “nowcasting” of imminent
Q2 / 2020
AN INDEPENDENT SUPPLEMENT FROM MEDIAPLANET WHO TAKE SOLE RESPONSIBILITY FOR ITS CONTENTS This article is sponsored by Arecor
Life Sciences
drugs to market quickly
Reformulating existing therapies
to better suit patient need can
Full campaign on businessandindustry.co.uk boost outcomes, slash drug
development timelines, and
facilitate affordable medicine.
Tackling crises with digital health technologies
F
“ ast-acting insulin, heat stable
vaccines, and ready-to-use
Faced with a global crisis, we
safely, are central too. liquid drug products are just a Dr Sarah Howell
have seen the best of digital
Get this right and the NHS can few examples of how advanced CEO, Arecor
technologies. The challenge
become a living laboratory for the product reformulation techniques are
now is keeping these advances
best of digital, bringing benefits to being used to improve outcomes.
in place and building on the
patients and the system. Approved combinations of advanced excipients can
momentum achieved.
T
Digital technologies have also enhance the properties of existing therapies to better suit
he development, shown great value in enabling new patient need and reduce the need for time-consuming
Andrew Davies implementation and use care solutions to relieve system safety trials,” said Arecor CEO Dr Sarah Howell.
Digital Health Lead, of digital technologies are pressures from ‘business as usual’ The company’s Arestat™ technology, for example,
Association of British
Healthtech Industries based on two key aspects; demands. The technologies fall into uses patented combinations of formulation excipients to
(ABHI) access to high quality, well curated four interlinked areas: modify the properties of complex proteins and peptides.
1
data sets, and patient ‘buy in’ for the Population management: She said: “We work with pharma and biotech
safe and ethical use of their data. Through large, integrated companies to develop formats of their products that
When rolling out such datasets, we can map regional would otherwise be unachievable.
technologies for use, we trends to identify those at risk in “The excipients we use are already approved for use.
must also consider the unique the population and deliver early That allows us to advance these products with superior
characteristics, culture and interventions. versions to be developed and brought to market very
ethical frameworks of a society. quickly.”
2
Triage and clinical
The need to digitise decision-making systems: Fast-acting insulin
COVID-19 has put digital Utilising machine learning Fast-acting insulin is one example of where these
technologies in the spotlight like to offer ‘clinical decision support’ reformulation techniques could deliver real patient
never before, with the need to technology can fast track patients to benefits, she said.
deliver care in alternative settings, the appropriate clinical pathway. “We have developed a novel formulation of insulin,
as well as contact tracing apps AT247, that accelerates its absorption post-injection.
3
through our smartphones. Digital diagnostics: That’s critical for people living with both type 1 and type
It is therefore critical that a By digitising diagnostics 2 diabetes, as it helps them manage their blood glucose,
comprehensive dialogue is held it becomes possible to particularly around mealtimes, where it rises very
with the public over the significant diagnose patients in the community sharply,” says Sarah.
benefits digital technologies can or home setting, thus speeding up “We’ve done it by taking an existing product, for which
deliver, and the trade-offs the public access to treatment and relieving the safety and effectiveness is known, and modifying its
will need to consider in gaining workforce pressures. properties.
those benefits. “The team now have some fantastic phase one clinical
4
At time of writing, there is Remote services: data to show AT247 performs significantly faster than the
debate over the use of a centralised The management of best-in-class mealtime insulin currently on the market
‘track and trace’ model – the patients becomes possible, for type 1 diabetes,” she says.
outcome and lessons learnt saving the need to visit hospitals, “If we can give people an insulin that works faster after
from which will be central to the clinics or GP practices. they have eaten, we can help them to keep their blood
advancement of this agenda. sugar in a healthy range. In turn, that will help them to
Building on the momentum avoid complications like heart disease, kidney failure,
The opportunity of the NHS’s data pool This is not about replacing limb amputation and eyesight loss.”
As the world’s largest single doctors with robots, rather, digital
health-payer system, the NHS technologies can empower patients, Applications
has a rich data pool. target earlier treatment, and free Other applications for the technology include
Large datasets, utilised up clinical time within stretched reformulating powder products into ready-to-use
effectively, mean three things for healthcare systems. liquids, removing the need for complex reconstitution
care: it can be more predictable, We have seen examples of all and the associated risk of dosing errors.
more personalised and more the above implemented rapidly Developing heat stable versions of drug products
precise. However, a systematic during the COVID-19 crisis. The currently stored and distributed in the cold chain
exercise of data management challenge now is keeping both is also possible.
to ensure usability is needed. the technological advances in “This can be particularly important for vaccines,
Appropriate regulation and the place and the ability to quickly where heat damage can lead to people being vaccinated
right mechanisms to introduce deploy technology to build on the with a product that has no potency,” explained Sarah.
such technologies into the NHS, momentum achieved. “Ultimately, advanced reformulation technologies
can greatly accelerate the path to market for affordable,
@Businessandindustry @MediaplanetUK @MediaplanetUK Please recycle efficacious medicines that tackle unmet patient need,”
she concluded.
Business Development Manager: Kirsty Elliott Email: kirsty.elliott@mediaplanet.com Content and
Production Manager: Kate Jarvis Managing Director: Alex Williams Head of Business Development: Ellie
McGregor Digital Manager: Jenny Hyndman Designer: Thomas Kent Content and Social Editor: Harvey Written by: Find out more at
O’Donnell Paid Media Strategist: Ella Wiseman Mediaplanet contact information: Phone: +44 (0) 203 642 Amanda Barrell arecor.com/
0737 E-mail: uk.info@mediaplanet.com All images supplied by Gettyimages, unless otherwise specified
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T
Global impact, unprecedented
he UK has played a central
challenges, shifting priorities – role in international efforts
these have been hot topics over on COVID-19, drawing on
the recent months. But, a less our inherent strength as the The global race to
world’s third largest biotech cluster.
highlighted topic that should be The sharing of data has been create a vaccine to
recognised, is the rapid rate of Phil Kemp
key to this response, from the generate immunity
sequencing of the very first
innovation and commercialisation Chief Executive,
Bruntwood SciTech COVID-19 genome in China, to in the population,
in the life sciences sector. sharing best practice in COVID-19 is well underway
Steve Bates
Chief Executive, testing strategies.
Reduced production time for new products BioIndustry Association We have seen Sanofi and GSK join manufacture of a COVID-19 vaccine.
New products and services have historically taken years forces, putting aside competition We formed a vaccine
to get from bench to bedside, particularly those in a and combining innovative manufacturing taskforce
clinical setting. technologies to find solutions. that includes companies and
Now, within the first year of a new decade, the brightest It is not just the larger organisations from the public
minds in the country from academia, industry and pharmaceutical companies and private sectors, academia,
clinical care have compressed this journey into a matter making a difference, we are also and universities.1
of weeks, and new innovations are being launched and seeing the likes of Exscientia The group is currently supporting
adopted at an unparalleled pace. using their AI platform to identify the Jenner Institute’s adenovirus
potential drugs and Oxford vaccine candidate and the work
The creation of the biggest testing network in British history Nanopore using their technology of Imperial College London on a
The UK government approached the Medicines to help with viral sequencing. mRNA vaccine.
Discovery Catapult to coordinate the establishment There is a long list of UK The manufacturing taskforce
of the national COVID-19 ‘megalabs’. companies of all sizes pivoting their will consider any COVID-19
Within three weeks, one of three national ‘Lighthouse research to focus on COVID-19. vaccines or therapies that emerge,
Lab’ testing centres had been established regardless of whether they are UK
at Alderley Park. Creation of an industry-led vaccine or internationally based and look
Together, these now make up the biggest network manufacturing taskforce to help where it can.
of diagnostic testing facilities in British history. The global race to create a vaccine The group is working closely with
The laboratory has rapidly become home to over to generate immunity in the the Government and reporting
80 scientists and volunteers, with the capacity to test population is well underway. directly to the Chief Scientific
up to 65,000 samples per day, enabling thousands To get a vaccine up and running Advisor, Sir Patrick Vallance.
of NHS and key workers to return to the frontline. and manufactured at scale, it is
important to bring together the Looking ahead
Increased collaboration between industry and clinical care molecular scientists and large-scale I am pleased to see the UK play such
Within two days of UK lockdown, Yourgene Health, biologics manufacturers. an important role in responding
an international molecular diagnostics company The BIA has built on its work to this health emergency. The
renowned for their expertise in prenatal testing and in response to the Ebola crisis, collaborations and manufacturing
Cystic Fibrosis, used their expertise and knowledge during which we completed a UK capacity developed to tackle the
to help join the early fight against COVID-19. manufacturing capacity audit of pandemic will provide solutions
They partnered with a specialist clinical diagnostics Read more at our members. now and in the future.
company to support the manufacturing of their test businessand We have repeated this exercise to
and set up a COVID-19 test facility at Citylabs, directly industry.co.uk ascertain the capacity to scale-up
surrounded by the NHS Trust hospitals in Manchester.
Yourgene have also developed their own PCR based
SARS-CoV-2 product that focuses on fast turnaround More Info:
and a low false negative rate. 1
Such collaboration has been at the fore. Companies Structure of the BIA’s vaccine
manufacturing taskforce:
such as Stream Bio have been collaborating with MIP Chair of the Industry-led Vaccine
Diagnostics on a rapid diagnostic and mass screening Manufacturing Group: Ian McCubbin
test for COVID-19.
Meanwhile, at Manchester Science Park global 1. Adenovirus vaccine: Cobra Biologics & Cell
molecular diagnostics company QIAGEN, Affinity and Gene Therapy Catapult
2. mRNA vaccine manufacture and formulation: CPI
Biomarker Labs and the University of Manchester have 3. Antibody: Alchemab and Kymab
supported patient testing on automated platforms, 4. Fill Finish: Innovate UK
illustrating the utility of existing high throughput 5. Supply Chain: Fujifilm
6. VMIC: VMIC
PCR and antibody-based testing platforms while 7. Communications: UCL and BIA
demonstrating the commercial potential for new
tests being developed within Greater Manchester. Supported by MHRA, UKRI, GSK and KTN
From testing to tech, one thing is consistent during
these ever-changing times: innovation continues.
Clusters drive global excellence in life sciences To find out more about the innovative
and pioneering work taking place in
London and the Greater South East’s
life sciences cluster please visit:
COVID-19 has driven collaboration on an unprecedented scale. Life sciences clusters are at the www.medcityhq.com
heart of this and need sustained support to thrive, showcase and drive global excellence.
T
he UK life sciences sector University of London have pooled The Advanced Therapies pandemic and the big shared global
has risen to address together to redeploy laboratories, Network for example, aims to bring health and care challenges of today
the challenges of this equipment and scientists. expert communities together, and the future.
extraordinary time by The Alliance’s response on testing leveraging deeper innovation In turn, the need for academic,
instantly refocussing efforts and has fed into the national effort to across regions and societies. industry and health system
resources to tackle the pandemic, tackle COVID-19. With joint funding from alliance, and the UK’s strength in
with innovation and partnership Meanwhile, cross-sector Research England, MedCity and this area, continues to make us a
at the heart of a united collaboration is driving significant the NHSA are also partnering global leader in life sciences.
commitment across clusters developments in treatment. on an international stage, For this legacy to live beyond
and nations worldwide. The OxVent group, comprising promoting inward investment and the pandemic, the Government
scientists, clinicians, engineers partnerships across Japan, South must continue a relentless pursuit
Clusters drive powerful collaboration and medical technology Korea, Israel, the Commonwealth of excellence by investing in
As a cluster, London and the manufacturers from King’s College Alliance and China. UK life science, research and
Greater South East of England London, University of Oxford As the champion for our regional development.
is a world leader in health and and Smith+Nephew mobilised cluster, MedCity acts as an expert, The time is now to secure
life sciences. quickly in response to COVID-19, neutral and non-political vehicle the future of the UK’s vital life
The global pandemic has developing the OxVent ventilator, to facilitate partnerships across sciences clusters
now driven collaboration on an which can be produced at speed the globe. to showcase
unprecedented scale by rapidly and scale, at significantly lower Clusters are uniquely placed and drive this
joining up components of the cost than alternatives. to draw on collective assets world-leading
research ecosystem. Maintaining the UK’s status as a and nurture long-term global excellence,
The London COVID-19 Alliance, global powerhouse for life sciences partnerships that advance particularly as
set up by MedCity with the city’s also relies on teamwork across scientific innovation and we forge new
world-leading universities, research clusters. excellence worldwide. international
institutes and industry, has united Through our close working trade deals.
to offer a collective response. relationship with the Northern Excellence requires investment
Alliance members including Health Science Alliance (NHSA), COVID-19 has accelerated joined
King’s College London, Imperial covering a joint population of 34 up working in the life sciences Neelam Patel
CEO,
College London, University million between us, we forge links community. This is vital to MedCity
College London and Queen Mary’s in specialist fields. successfully tackling both this
Contact us today
We’re looking to engage with
businesses that share our aspirations
to develop the life sciences sector
in Wales. Key areas of development
include, advanced therapies, precision
medicine, digital health and healthy
ageing. Visit our website today to find
out more lshubwales.com
Global industries and local businesses in Wales have been adapting and
innovating at significant pace and scale in response to COVID-19.
T
he Welsh life sciences have been qualified by both Public Repurposing factories to
sector (including medical Health Wales and Public Health manufacture PPE
technologies, testing, England, detect antibodies that Similarly, following an initial
diagnostics and medicine) confirm a previous and recent submission to Life Sciences Hub
and businesses beyond have played COVID-19 infection, letting people Wales, long-standing Welsh
a significant role in supporting know whether they have had the manufacturer BCB International has
health and social care services virus. The new-style blood tests are been working to help NHS Wales get
across Wales. At the end of March, being rolled out across the UK as key supplies to frontline staff.
the First Minister of Wales and part of the national testing strategy. The organisation quickly
Cari-Anne Quinn Life Sciences Hub Wales issued a International manufacturer, converted its factory base in Llanelli
Chief Executive Officer, direct call to industry in support of PerkinElmer also responded to our to make high strength alcohol
Life Sciences
Hub Wales
infection control products, medical industry call with an offer to source sanitiser and PPE first responder
devices and digital solutions. testing kits and lab equipment medical equipment for NHS Wales
This activity led to an required to process them. With and key workers. Since its original
overwhelming response from established bases in Wales and the submission, it has supplied over
businesses across Wales and global UK, PerkinElmer was able to work 500,000 litres of its hand-sanitiser
leaders including PerkinElmer and quickly with its UK customers to to the NHS Wales and continues to
Ortho Clinical Diagnostics. Working requisition technology devices that provide PPE including gowns, gloves,
alongside health and social care could be repurposed for COVID-19 masks and shields.
buyers, Life Sciences Hub Wales testing. These are just a small number
managed the high volume of supply of the companies that we have had
offers received from businesses, Using recyclable material to make PPE the privilege to work with over
enabling them to focus on the most Caerphilly-based Transcend recent months – businesses that are
appropriate offers of support. This Packaging, manufacturers of placing Wales at the forefront of the
activity helped facilitate and deliver sustainable packaging, including life sciences sector whilst driving
critical products to staff on the paper straws for quick serve innovation, development and
frontline. restaurants, became PPE certified delivery at significant pace.
so that they could create millions of Our ambition is to continue
At the forefront of antibody testing protective face shields that are now the acceleration and adoption of
We worked with Ortho Clinical being supplied throughout the UK innovation across health and social
Diagnostics, a global provider of and across the globe. care beyond the current crisis -
testing solutions for a wide range We worked with them to adapt ensuring a more resilient and robust
of diseases and medical conditions production and ensure face shields healthcare system in Wales and
to produce antibody tests at its met all requirements. As a result, across the globe.
state-of-the-art facility in Pencoed, over three million shields have been
Bridgend and is now one of three produced, with over 1.5 million going
companies worldwide to provide a directly into the Welsh NHS supply Read more at
COVID-19 antibody test for the UK. chain, councils, care homes, retailers businessand
industry.co.uk
The made-in-Wales tests, which and factories.
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%$1$1$:,7+&2/'
happens as they decay is accelerated because their
cells’ internal membranes are damaged, releasing
enzymes and other substances. Banana skin can
This is counterintuitive to those of us brought blacken overnight as it softens and breaks down.
up to believe that chilling foodstuffs slows decay,
What’s happening is that the membranes that keep
but a simple experiment will show us if it’s true
the contents of the various compartments inside a
or not. cell separate are essentially two layers of slippery
IDWPROHFXOHVRUOLSLGV&KLOOWKHVHPHPEUDQHVDQG
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fresh banana skins) and other molecules that are normally kept apart
mix and kick off chemical reactions that speed up
** a fridge (and possibly a domestic freezer) the softening of the fruit.
** lemon juice The skin goes black because of the action of an
enzyme called polyphenol oxidase. The enzyme
:+$7'2,'2" encourages the breakdown of smelly compounds
Place one banana in the fridge and leave the other called phenols in the banana skin. This produces
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banana three or four times a day and note the gives human skin and hair its colour. Just as when
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experiment, rub a third banana with lemon juice increases in your skin, giving you a tan, as the
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While many fruits are stabilised by refrigeration,
most tropical and subtropical fruits, and bananas
in particular, just can’t handle the cold.
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The cold itself does not speed up the browning Decay can be slowed by acids, which prevent the
part of the reaction, it just starts it off earlier. release of the polyphenol oxidase enzyme. This is
In fact, once your banana is damaged by the cold why adding lemon juice – which is rich in citric
in the fridge, if you take it out again the browning DFLGbśWRVNLQVFDQVORZWKHEODFNHQLQJSURFHVV
process will speed up because the reaction that A similar slowing of the breakdown process can be
causes the browning, once it is under way, is seen if bananas are coated in wax; this stops
speeded up by heat. oxygen reaching the skin and speeding up decay.
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ACROSS DOWN
1 Gold minerals reported to make up ex-cow (7) 1 Beginning to admire China? Quick
5/15/21 Ex-carnivore’s worn-out boots Maybe Kennedy did (5) Crossword #60
reattached (5-7,3) 2 Predator that follows female
Answers
8 Ex-marsupial designs hat nicely (9) deer, by the sounds (3)
9 Dolphin, turtle and guillemot’s tails may be 3 Ruder word for bottom covered up by ACROSS 1 Stanisław Lem, 10 Aleph,
caught in this (3) carbon monoxide detector, finally (7) 11 Analgesic, 12 Geoduck, 13 Essence,
10 Ex-birds’ note repeated sound at first (5) 4 Migrants such as Jonathan and Taylor? (6) 14 Datum, 16 Lubricant, 19 Paradigms,
12 Isn’t one stressed by this? (7) 5 Firm part of vessel (5) 20 Seoul, 22 Cochlea, 25 Houston,
6 See 13 Across 27 Amygdalin, 28 L-dopa,
13/6 Eccentric botanist recoded
29 Ursula Le Guin
ex-marsupial (6,9) 7 Old metal cat gutted, like many
14 Time to go after half of Earth’s air or less (2,4) creatures found here (7)
DOWN 2 The Doctor, 3 Nehru, 4 Spark
17 Russia and Europe getting into dispute 11 Unfairly depict spy as bad-tempered (9) plug, 5 Agate, 6 Logistics, 7 Meson,
for cargo (7) 13 Shortfall appears somewhat 8 Ancient, 9 Tagged, 15 Mudslides,
19 Remote road beginning to end (5) chaotic if edited in reverse (7) 17 Bisphenol, 18 A fortiori, 19 Pickaxe,
21 See 5 15 See 5 Across 21 Linear, 23 Coypu, 24 Allyl, 26 Uhlig
22 Cardiology department’s head moving 16 Carbohydrate feature: carbon, hydrogen (6)
to the ground (9) 18/23 Ex-bird offering not-so-colourful
24 Unspoken thanks - “cheers” interpreted conversation, they say (5,3)
thus, originally (5) 20 Gas causing trouble in outskirts
25 Physiologist injects pig family of Roehampton (5)
with drop of dye (7) 23 See 18
Our crosswords are
now solvable online
newscientist.com/crosswords
Quick
quiz #57
Answers
R
r
1 Zimbabwe. The
site is now known 5
as Great Zimbabwe
2 The peanut
or groundnut Call the radius of the room R, and
3 Katherine Johnson
the radius of the central pillar r.
The area of the carpet is:
4 The Olduvai πR2 - πr2 = π(R2 - r2 ).
Gorge, one of the But from Pythagoras we know
most famous of all
52 + r2 = R2, and so R2 - r2 = 25
palaeoanthropological
sites So the area of the carpet is 25π,
or roughly 78.5 square metres.
5 The Hayden
Planetarium at the
Rose Center for Earth
and Space
year’s list contains some firm to indulge in a spate of ill-judged mark a turning point in Feedback’s
favourites (note the clever double limerick composition, the fruits of working life. And, perhaps, in Written by Gilead Amit