Drug Study
Drug Study
Drug Study
CALCIUM
INDICATION to treat or prevent low calcium levels
Calcium carbonate is a calcium supplement, Vitamin D3 is a fat-soluble
ACTION sterol, it aids in the regulation of calcium and phosphate homeostasis and
bone mineralization.
FOLIC ACID
INDICATION treatment of megaloblastic anemias of pregnancy
Stimulates production of RBCs, WBCs, and platelets in patients with
ACTION megaloblastic anemias. Include improved symptoms of glossitis, diarrhea,
constipation, weight loss, irritability, fatigue, restless legs, diffuse muscular
pain, insomnia, forgetfulness, mental depression, pallor.
Folic acid alone for pernicious anemia or other vitamin B 12 deficiency states;
CONTRAINDICATIO normocytic, refractory, aplastic, or undiagnosed anemia.
N
may antagonize effects of folate therapy; phenytoin metabolism may be
DRUG increased, thus decreasing its levels in folate-deficient patients.
INTERACTIONS
Although doses up to 5 mg daily have been safely used in some research,
ADVERSE doses of folic acid greater than 1 mg daily might cause abdominal cramps,
REACTION diarrhea, rash, sleep disorders, irritability, confusion, nausea, stomach upset,
behavior changes, skin reactions, seizures, gas, excitability, and other side
effects.
- Obtain a careful history of dietary intake and drug and alcohol usage
NURSING prior to start of therapy. Drugs reported to cause folate deficiency
RESPONSIBILITIES include oral contraceptives, alcohol, barbiturates, methotrexate,
phenytoin, primidone, and trimethoprim. Folate deficiency may also
result from renal dialysis.
- Keep physician informed of patient's response to therapy.
- Monitor patients on phenytoin for sub therapeutic plasma Levels.