Gas Exchange and Smoking XI312 RAMA

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XI312 Maheswara Mahirataqi GAS EXCHANGE & SMOKING

Movement of gases into & out of an


Structure of the human Diseases
gas exchange system
Definition organisms body across a gas exchange
surface

• breathing movements, which draw air • Chronic obstructive pulmonary disease (COPD) This
from outside the body into the lungs, is a condition in which a person has chronic bronchitis
and then push it out again, this maintains and emphysema. it is difficult to get sufficient oxygen
a relatively high concentration of oxygen into the blood to support activity.
Gas Exchange at the and low concentration of carbon dioxide
alveolar surface in the alveoli • Chronic bronchitis Various components of cigarette
smoke including tar cause goblet cells to increase
• blood flow past the alveolus, which mucus production and cilia to bear less strongly. This
brings deoxygenated blood and carries causes mucus to build up. which may partially block
away oxygenated blood alveoli This makes gas exchange more difficult, as the
diffusion distance between the air in the alveoli and the
blood in the capillaries is greater. The mucus may
become infected with bacteria, causing bronchitis
Smokers often have chronic (long-lasting) bronchitis.

• Emphysema the Smoking causes inflammation in the


lungs. This involves the presence of increased numbers
of white blood cells, some of which secrete chemicals
that damage elastic fibres. This makes the alveoli less
elastic They may burst, resulting in larger air spaces.

• Lung cancer Various components of tar can cause


changes in the DNA in body cells, including the genes
• Cartilage in the walls of the trachea and bronchi that control cell division, which can cause cancer. These
provides support and prevents the tubes collapsing substances are therefore carcinogens. Cancers caused
when the air pressure inside them is low. by cigarette smoke are most likely to form in the lungs
but may form anywhere in the gas exchange system,
• Ciliated epithelium is found lining the trachea, bronchi and also in other parts of the body.
and some bronchioles. It is a single layer of cells whose
outer surfaces are covered with many thin extensions • Atherosclerosis is a thickening and loss of elasticity in
(cilia), which are able to move. They sweep mucus the walls of arteries. It is caused by build-up of plaques
• TAR a mixture of substances including
upwards towards the mouth, helping to prevent dust in the blood vessel wall. The plaques contain
various chemicals that act as
particles and bacteria reaching the lungs. cholesterol and fibres.
carcinogens.
• Goblet cells are also found in the ciliated epithelium. • Etc.
• Nicotine an addictive substance that
They secrete mucus, which traps dust particles and
affects the nervous system by binding
bacteria. Cigerate contains
receptors on neurones (nerve cells) in
the brain and other parts of the body.
• Smooth muscle cells are found in the walls of the
trachea, bronchi and bronchioles. This type of muscle
• Carbon Monoxide can reduce the
can contract slowly but for long periods without tiring.
amount of haemoglobin available to
When it contracts, it reduces the diameter of the tubes.
combine with oxygen.
During exercise it relaxes, widening the tubes so more
air can reach the lungs.

• Elastic fibres are found in the walls of all tubes and


between the alveoli. When breathing in, these fibres
stretch to allow the alveoli and airways to expand When
breathing out, they recoil, helping to reduce the volume
of alveoli and expel air out of the lungs

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