Sex Determination (Class-12)

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ARMY PUBLIC SCHOOL GOPALPUR

CLASS-XII Science SUBJECT – BIOLOGY

CHAPTER–5 PRINCIPLES OF INHERITANCE AND VARIATION

NOTES

Characteristic of Linked Genes


Genes on different chromosomes assort independently giving a 1: 1: 1: 1 test cross ratio. Linked
genes do not assort independently but tend to stay together in the same combination as they
were in the parents.

Types of Linkage
Morgan and his co-workers by their investigation on the Drosophila found two types of linkage

1. Complete linkage and
2. Incomplete linkage.

Complete Linkage
 The complete linkage is the phenomenon in which parental combinations of characters
appear together for two or more generations in a continuous and regular fashion.
 In this type of linkage genes are closely associated and tend to transmit together.

Incomplete Linkage
 The linked genes which are widely located in chromosomes and have chances of
separation by crossing over are called incompletely linked genes and the phenomenon
of their inheritance is called incomplete linkage.
 The linked genes do not always stay together because homologous non-sister
chromatids may exchange segments of varying length with one another during meiotic
prophase. This sort of exchange of chromosomal segments in between homologous
chromosomes is known as crossing over.
Example - The incomplete linkage has been reported in female Drosophila and various other
organisms such as tomato, maize, pea, mice, poultry and man, etc.
Significance of Linkage
The phenomenon of linkage has one of the great significance for the living organisms in that it
reduces the possibility of variability in gametes unless crossing over occurs.

Sex Determination by chromosomes:-


Those chromosomes which are involved in the determination of sex of an individual are called
sex chromosomes while the other chromosomes are called autosomes.

Sex determination

Male Heterogamy Female heterogamy

XX - XY XX-XO ZZ-ZW ZZ-ZO


Female male female male male female male
female

1) XX – XY type: In most insects including fruit fly Drosophila and mammals including human
beings the females possess two homomorphic sex chromosomes, named XX. The males contain
two heteromorphic sex chromosomes, i.e., XY. Hence the males produce two types of gametes
/ sperms, either with X-chromosome or with Y-chromosome, so they are called Heterogamety.

X Y (male)

X XX XY
X XX XY

2) ZZ – ZW type: In birds and some reptiles, the males are represented as ZZ


(homogamety) and females are ZW (heterogamety).
Z W (female)
Z ZZ
Z ZW

Z ZZ
Z ZW

3) XX – XO type: In round worms and some insects, the females have two sex chromosomes,
XX, while the males have only one sex chromosomes X. There is no second sex chromosome.
Therefore, the males are designated as XO. The females are homogametic because they
produce only one type of eggs. The males are heterogametic with half the male gametes
carrying X-chromosome while the other half being devoid of it.
X O (male)
XX XO
X
XX XO
X

4)ZZ –ZO type - Type in butterfly and moth the female have only one sex chromosome Z, there
is no second sex chromosome therefore female are designated as ZO. The female is
heterogametic while the male have two ZZ sex chromosome

Z O (female)

ZZZ ZO

ZZZ ZO

Sex determination in Humans:


Human beings have 22 pairs of autosomes and one pair of sex chromosomes. All the ova
formed by female are similar in their chromosome type (22+X). Therefore, females are
homogametic. The male gametes or sperms produced by human males are of two types,
(22+X) and (22+Y). Human males are therefore, heterogametic. The two sexes produced in the
progeny is 50:50 ratios.

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