Objectives: at The End of This Activity, You Should Be Able To

Download as pdf or txt
Download as pdf or txt
You are on page 1of 3

Laboratory Activity 1: CAPILLARY FRAGILITY TEST

NAME: BALDO, GRYZELLE MAE B. Rating:


Class schedule: FRIDAY 2:00-5:00 (LCA-2) Date submitted:

This test measures the ability of small capillaries to retain blood when subjected to increased
hydrostatic pressure and anoxia. It is a non-specific evaluation to measure capillary weakness and deficiencies
in platelet number and function. Decreased capillary resistance causes the capillaries to rupture which leads to
bleeding and formation of petechiae.

Objectives: At the end of this activity, you should be able to:


▪ properly perform the capillary fragility test (tourniquet); and
▪ discuss the clinical significance of the test in the screening of primary hemostatic disorders.

Materials Needed: Blood pressure cuff (or tourniquet/rubber or cloth strip), timer

Procedure: Rumpel-Leede Tourniquet Test

1. Examine the forearm, hand, and fingers to make certain that no petechiae are present.
2. With a blood pressure cuff, apply 100 mmHg pressure to upper arm.
🢩 To those who do not have a blood pressure cuff, use a tourniquet or rubber/cloth strip instead.
Apply the tourniquet not too tight, not too loose to employ just enough pressure.
3. Maintain pressure for 5 minutes.
4. Release cuff and wait for 5 – 10 minutes before making a final reading.
5. Examine the forearm, hands and fingers for petechiae.

1+ : A few petechiae on the anterior part of the forearm


2+ : May petechiae on the anterior part of the forearm
3+ : Multiple petechiae over the whole arm and back of the hand
4+ : Confluent petechiae on the arm and back of the hand
Note: Disregard any petechiae within ½ inch of the blood pressure cuff (tourniquet)
because this may be due to pinching of the skin by the cuff.

6. Count the number of petechiae and roughly interpret as follows:

Illustrate:
1. Petechiae, purpura, ecchymosis
2. Photo of your individual results.

Enhancement Questions:
Reading Assignment:
1. What are petechiae, ecchymoses, purpura?
2. Enumerate and describe the different vascular disorders that lead to bleeding.
3. Clinical significance of CFT
Research Question: (to be checked using the rubrics)
1. Give the factors affecting the results of the test
2. Give and explain the contraindications of CFT.
Patient 1
Result: 1+ : A few petechiae on the anterior part of the forearm

Patient 2
Result: 1+ : A few petechiae on the anterior part of the forearm
QUESTIONS FOR RESEARCH:

1. Give the factors affecting the results of the test

● Failure to keep the cuff inflated for 5 minutes.


● Elasticity of the skin.
● Premenstrual women experience transient episodes of increased capillary fragility.
● Women especially those with sun damaged skin, can have increased capillary fragility.
● Prolonged use of steroids increased capillary fragility.
● Insufficient intake of Vitamin C
● Use of certain drugs
- Aspirin
- Warfarin
- Sulfonamide and Iodides

References: Mosby’s Candian Manual of Diagnostic and Lab Test; Pagana, K. (2013) page 648
Rodak’s Hematology: Clinical Principle and Applications; Keohane, E.M. et. Al (5th Ed) page 728- 730

2. Give and explain the contraindications of CFT.


CFT is not advisable to perform in presence of any of these diseases:
- Viral infections including enteroviruses and influenza
- Neisseria meningitidis (meningococcal) disease
Other causes of bacteremia including Streptococcus pneumoniae and Haemophilus influenzae
- Other diseases including Henoch Schonlein purpura, ITP and leukaemia
- Illness characterised by vomiting or coughing causing petechiae around the head and neck
Because this diseases ciseases causes petechiae and purpura
Reference. Joly BS, Coppo P, Veyradier A. An update on pathogenesis and diagnosis of thrombotic thrombocytopenic purpura.
Expert Rev Hematol. 2019 Jun;12(6):383-395

You might also like