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    Drug Mechanism of Action/side Effects Indication/ Contraindication Nursing Responsibilities

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    Sheryhan Tahir Bayle
    Cefuroxime (Zinacef) is a second-generation cephalosporin antibiotic used to treat susceptible infections caused by streptococci, pneumococci, staphylococci, and other bacteria. It works by binding to bacterial cell membranes and inhibiting cell wall synthesis. Common side effects include discomfort with intramuscular injections, oral thrush, mild diarrhea, and abdominal cramping. Nurses monitor patients for signs of infection, renal impairment, and gastrointestinal issues while on cefuroxime therapy.

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    Drug Mechanism of Action/side Effects Indication/ Contraindication Nursing Responsibilities

    Uploaded by

    Sheryhan Tahir Bayle
    76 views2 pages
    Cefuroxime (Zinacef) is a second-generation cephalosporin antibiotic used to treat susceptible infections caused by streptococci, pneumococci, staphylococci, and other bacteria. It works by binding to bacterial cell membranes and inhibiting cell wall synthesis. Common side effects include discomfort with intramuscular injections, oral thrush, mild diarrhea, and abdominal cramping. Nurses monitor patients for signs of infection, renal impairment, and gastrointestinal issues while on cefuroxime therapy.

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    cefuroxine

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    Cefuroxime (Zinacef) is a second-generation cephalosporin antibiotic used to treat susceptible infections caused by streptococci, pneumococci, staphylococci, and other bacteria. It works by binding to bacterial cell membranes and inhibiting cell wall synthesis. Common side effects include discomfort with intramuscular injections, oral thrush, mild diarrhea, and abdominal cramping. Nurses monitor patients for signs of infection, renal impairment, and gastrointestinal issues while on cefuroxime therapy.

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    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd
    Download as docx, pdf, or txt
    76 views2 pages

    Drug Mechanism of Action/side Effects Indication/ Contraindication Nursing Responsibilities

    Uploaded by

    Sheryhan Tahir Bayle
    Cefuroxime (Zinacef) is a second-generation cephalosporin antibiotic used to treat susceptible infections caused by streptococci, pneumococci, staphylococci, and other bacteria. It works by binding to bacterial cell membranes and inhibiting cell wall synthesis. Common side effects include discomfort with intramuscular injections, oral thrush, mild diarrhea, and abdominal cramping. Nurses monitor patients for signs of infection, renal impairment, and gastrointestinal issues while on cefuroxime therapy.

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    © All Rights Reserved
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    Download as docx, pdf, or txt
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    Drug Mechanism of action/Side effects Indication/ Nursing responsibilities

    Contraindication
    Brand name: Action Indication Baseline assessment:
    Treatment of susceptible infections due to
    Zinacef group B streptococci, pneumococci, Obtain CBC, renal function tests. Question
    staphylococci, H. influenzae, E. coli, Contraindication for history of allergies, particularly
    Enterobacter, Klebsiella, including cephalosporins, penicillin.
    Generic name:
    acute/chronic bronchitis, gonorrhea, History of
    Intervention/evaluation:
    impetigo, early Lyme disease, otitis media, hypersensitivity/anaphylactic
    Cefuroxime
    pharyngitis/tonsillitis, sinusitis, skin/skin
    reaction to cefuroxime, Assess oral cavity for white patches on
    structure, UTI, perioperative prophylaxis. mucous membranes, tongue (thrush). Monitor
    Classification: Binds to bacterial cell membranes, inhibits cephalosporins.
    daily pattern of bowel activity, stool
    cell wall synthesis. consistency.
    PHARMACOTHERAPEUTIC: Therapeutic Effect: Bactericidal. Cautions: Severe renal
    Mild GI effects may be tolerable (increasing
    Side Effects impairment, history of penicillin severity may indicate onset of antibiotic-
    Second-generation allergy. Pts with hx of colitis, GI associated colitis).
    Frequent: Discomfort with IM Monitor I&O, renal function tests for
    malabsorption, seizures.
    cephalosporin administration, oral candidiasis (thrush), nephrotoxicity.
    mild diarrhea, mild abdominal cramping, Be alert for super infection: fever, vomiting,
    vaginal candidiasis. diarrhea, anal/genital pruritus, oral mucosal
    CLINICAL: Antibiotic. changes (ulceration, pain, erythema).
    Occasional: Nausea, serum sickness–like
    reaction (fever, joint pain; usually occurs Patient/family teaching
    Route: after second course of therapy and resolves • Discomfort may occur with IM injection. •
    Doses should be evenly spaced.
    after drug is discontinued).
    Dosage: 40mg/kg/day • Continue antibiotic therapy for full length of
    Rare: Allergic reaction (rash, pruritus,
    treatment.
    urticaria), thrombophlebitis (pain, redness, • May cause GI upset (may take with food,
    Frequency: q8 swelling at injection site). milk).

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