Case Scenario Typhoid Fever
Case Scenario Typhoid Fever
Case Scenario Typhoid Fever
College of Nursing
West Ave., Molo. Iloilo City
NCM 107 RLE
VII. DRUG STUDY
Prescribed Drug Classification & Mechanism of Indication Contraindication Side Effects/Adverse Reaction Nursing Responsibility
Action
Generic Name: Classification: Used in the management Contraindications: Side Effect: Frequent: ● Check doctor’s order
Tetracycline and treatment of variety Hypersensitivity to Dizziness, light-headedness, ● Ensure medicines are
PHARMACOTHERAPEUTIC:
of infectious disease; tetracycline diarrhea, nausea, vomiting, monitored and administered
Tetracycline
Brand Name: Treatment of susceptible abdominal cramps, correctly.
Cautions: Sun, ultraviolet
Tetracap CLINICAL: Antibiotic infections due to photosensitivity (may be ● Question for history of
light exposure (severe
Rickettsiae, M. severe). Occasional: allergies, esp. tetracyclines,
Mechanism of Action: Inhibits photosensitivity reaction).
Dosage: 250 mg, 500 pneumoniae, C. Pigmentation of skin or mucous sulfite.
bacterial protein synthesis by Renal, hepatic
mg trachomatis, C. psittaci, membranes, anal/genital ● Assess skin for rash.
binding to ribosomes. impairment. Avoid use
H. ducreyi, Yersinia pruritus, stomatitis, ● Monitor daily pattern of
Route:PO during tooth development
Therapeutic Effect: pestis, Francisella discoloration of teeth. bowel activity, stool
(children 8 yrs or
Frequency: q12h Bacteriostatic. tularensis, Vibrio consistency
younger). Do not use Adverse Reaction:
cholerae, Brucella spp.; ● Monitor food intake,
Timing: 8:00-8:00 during pregnancy Superinfection (esp. fungal),
tolerance.
anaphylaxis, elevated
● Be alert for superinfection
intracranial pressure (ICP) may
(diarrhea, stomatitis,
occur. Bulging fontanelles
anal/genital pruritus).
occur rarely in infants.
● Monitor B/P, level of
consciousness (potential for
elevated ICP).
Prescribed Drug Classification & Mechanism Indication Contraindication Side Effects/Adverse Reaction Nursing Responsibility
of Action
ILOILO DOCTORS’ COLLEGE
College of Nursing
West Ave., Molo. Iloilo City
NCM 107 RLE
Generic Name: Classification: Particularly effective History of Side Effect: ● Check doctor’s order
CHLORAMPHENICOL ANTIINFECTIVE; ANTIBI against Salmonella typhi and hypersensitivity or Hypersensitivity, angioedema, dy ● Ensure medicines are monitored and
OTIC other Salmonella sp, Streptoc toxic reaction to spnea, administered correctly.
Brand Name: occus pneumoniae, chloramphenicol, fever, anaphylaxis, superinfectio ● Monitor blood studies.
Chloromycetin Mechanism of Action: Neisseria, meningeal ns, Gray syndrome
pregnancy (category Chloramphenicol should be
Believed to act by binding to infections caused by H.
C); lactation. History or discontinued upon appearance of
Dosage: 250 mg the 50S ribosome of bacteria influenzae, and infections GI: Nausea, vomiting, diarrhea,
family history of drug- leukopenia, reticulocytopenia,
and thus interfering with involving Bacteroides perianal irritation, enterocolitis,
induced bone marrow thrombocytopenia, or anemia.
Route:PO protein synthesis. fragilis and other anaerobic glossitis, stomatitis, unpleasant
depression, ● Check temperature at least q4h.
organisms, Rickettsia taste, xerostomia.
Frequency: q6h Usually chloramphenicol is
rickettsii (cause of Rocky Adverse Reaction: discontinued if temperature remains
Timing: 12:00-6:00 Mountain spotted fever) and including blood problems and normal for 48 h.
other rickettsiae, the eye problems. Symptoms of the ● Monitor I&O ratio or pattern: Report
lymphogranuloma-psittacosis blood problems include pale any appreciable change.
group (Chlamydia), and Myco skin, sore throat and fever, ● Lab tests: Perform bacterial culture
plasma. unusual bleeding or bruising, and and susceptibility tests prior to first
unusual tiredness or weakness dose and periodically thereafter.
● Observe the patient closely, because
blood studies are not always reliable
predictors of irreversible bone marrow
depression.