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Meclizine

Meclizine is an antihistamine used to treat and prevent vertigo, nausea, vomiting and dizziness associated with motion sickness. It works by reducing sensitivity of the inner ear and blocking cholinergic synapses in the brain. Common side effects include drowsiness, dry mouth and blurred vision. As a nurse, responsibilities include ensuring the drug is chewed or crushed before swallowing with liquid, supervising ambulation due to drowsiness, and assessing effectiveness in treating vertigo and instructing patients to report any side effects.

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Gwyn Rosales
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1K views

Meclizine

Meclizine is an antihistamine used to treat and prevent vertigo, nausea, vomiting and dizziness associated with motion sickness. It works by reducing sensitivity of the inner ear and blocking cholinergic synapses in the brain. Common side effects include drowsiness, dry mouth and blurred vision. As a nurse, responsibilities include ensuring the drug is chewed or crushed before swallowing with liquid, supervising ambulation due to drowsiness, and assessing effectiveness in treating vertigo and instructing patients to report any side effects.

Uploaded by

Gwyn Rosales
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as DOCX, PDF, TXT or read online on Scribd
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Nursing

Name of Drug Classification Mechanism of Action Indication Contraindication Side Effects


Responsibilities
Generic Name: Pharmacologic Class: Pharmacodynamics General Indication: - Hypersensitivity to CNS: Dizziness, Before Drug
Meclizine Piperazine derivative or Mechanism of  To prevent and meclizine or its drowsiness, euphoria, Administration
Hydrochloride Action: treat vertigo components excitement, fatigue, - The drug can be
Therapeutic Class: May inhibit nausea and  Management of - GI obstruction hallucinations, given without regard to
Trade/Brand Name: Antivertigo, vomiting by reducing nausea, vomiting, headache, insomnia, meals.
Antivert, Bonamine Antiemetic sensitivity of and dizziness nervousness,
(CAN), Bonine, labyrinthine apparatus associated with restlessness, vertigo During Drug
Dizmiss, Dramamine Pregnancy Category: and blocking motion sickness Administration
II, Meclicot, B cholinergic synapses in CV: Hypotension, - Ensure that chewable
Medivert, Meni-D the brain’s vomiting Patient’s Indication: palpitations, tablets are chewed or
center To treat patient’s vertigo tachycardia crushed before being
Minimum dose: which is associated with swallowed with a
25 mg/day Pharmacokinetics: diseases affecting EENT: Blurred vision; liquid.
Absorption: Readily vestibular system diplopia; dry mouth, - Supervision of
Maximum dose: absorbed from GI tract. nose, and throat; ambulation since drug
100 mg/day tinnitus may cause drowsiness.
Onset: 1 h.
Patient’s Dose: GI: Abdominal pain, After Drug
25 mg PO TID PRN Duration: 8–24 h. anorexia, constipation, Administration
for vertigo diarrhea, nausea, - Assess effectiveness
Distribution: Crosses vomiting of drug and inform
Route: placenta. prescriber when
PO GU: Urinary frequency prescribed for vertigo.
Elimination: Primarily and hesitancy, urine - Instruct patient to
Frequency: in feces. retention report blurred vision or
TID PRN for vertigo drowsiness.
Half-Life: 6 h. RESP: Bronchospasm, - Caution patient to
thickening of avoid hazardous
Availability: respiratory secretions activities until drug’s
Tablet- 25-100 mg CNS effects are
Capsule SKIN: Jaundice, rash, known.
urticaria
Content:
Meclizine
hydrochloride; corn
starch; dibasic calcium
phosphate; magnesium
stearate; polyethylene
glycol; sucrose

References:

Vallerand, A., Sanoski, C., & Deglin, J. (2017). Drug Guide for Nurses. 15th Ed. FA Davis Company: Philadelphia

Schull, P. D. (2013). McGraw-Hill nurses drug handbook. New York: McGraw-Hill Medical.

JONES & BARTLETT LEARNING. (2018). Nurses Drug Handbook. SUDBURY.

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