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    MMC 1

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    Sigit Adi
    This supplementary appendix provides additional data to support the findings of the main document. It includes 4 figures (A-D) comparing the immunogenicity of the mRNA BNT162b2 vaccine and the inactivated CoronaVac vaccine. Figures A and B show RBD ELISA and sVNT responses before and after the first and second doses of each vaccine. Figures C and D show PRNT50 and PRNT90 titers at the same timepoints.

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    MMC 1

    Uploaded by

    Sigit Adi
    35 views2 pages
    This supplementary appendix provides additional data to support the findings of the main document. It includes 4 figures (A-D) comparing the immunogenicity of the mRNA BNT162b2 vaccine and the inactivated CoronaVac vaccine. Figures A and B show RBD ELISA and sVNT responses before and after the first and second doses of each vaccine. Figures C and D show PRNT50 and PRNT90 titers at the same timepoints.

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    This supplementary appendix provides additional data to support the findings of the main document. It includes 4 figures (A-D) comparing the immunogenicity of the mRNA BNT162b2 vaccine and the inactivated CoronaVac vaccine. Figures A and B show RBD ELISA and sVNT responses before and after the first and second doses of each vaccine. Figures C and D show PRNT50 and PRNT90 titers at the same timepoints.

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Download as pdf or txt
    35 views2 pages

    MMC 1

    Uploaded by

    Sigit Adi
    This supplementary appendix provides additional data to support the findings of the main document. It includes 4 figures (A-D) comparing the immunogenicity of the mRNA BNT162b2 vaccine and the inactivated CoronaVac vaccine. Figures A and B show RBD ELISA and sVNT responses before and after the first and second doses of each vaccine. Figures C and D show PRNT50 and PRNT90 titers at the same timepoints.

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    Supplementary appendix

    This appendix formed part of the original submission. We post it as supplied by the
    authors.

    Supplement to: Lim W, Mak L, Leung GM, Cowling BJ, Peiris M. Comparative
    immunogenicity of mRNA and inactivated vaccines against COVID-19. Lancet Microbe
    2021; published online July 15. https://doi.org/10.1016/S2666-5247(21)00177-4.
    A RBD ELISA
    B sVNT
    5 100%
    RBD ELISA (OD450 value)

    4 80%

    sVNT inhibition (%)


    3 60%

    2 40%

    1 20%

    0 0%
    BNT162b2 CoronaVac BNT162b2 CoronaVac BNT162b2 CoronaVac BNT162b2 CoronaVac BNT162b2 CoronaVac BNT162b2 CoronaVac

    Pre-vaccination After After Pre-vaccination After After


    first dose second dose first dose second dose

    C PRNT50 D PRNT90

    ≥320 ≥320
    160 160
    PRNT50 titer

    PRNT90 titer

    80 80
    40 40
    20 20
    10 10
    <10 <10
    BNT162b2 CoronaVac BNT162b2 CoronaVac BNT162b2 CoronaVac BNT162b2 CoronaVac BNT162b2 CoronaVac BNT162b2 CoronaVac

    Pre-vaccination After After Pre-vaccination After After


    first dose second dose first dose second dose

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