Pharmacy Preceptors Guild of The Philippines: Jonathan B. de Guzman OLFU - Valenzuela Section 8
Pharmacy Preceptors Guild of The Philippines: Jonathan B. de Guzman OLFU - Valenzuela Section 8
Pharmacy Preceptors Guild of The Philippines: Jonathan B. de Guzman OLFU - Valenzuela Section 8
Objective:
Case:
A 20-year-old man, height 5.8 ft and weight 65 kg, with no past medical history presented to a primary
stroke center with sudden left sided weakness and imbalance followed by decreased level of
consciousness. Head CT scan showed no hemorrhage, no acute ischemic changes, and a hyper-dense
basilar artery. The CT angiography shoed a mid-basilar occlusion. Physician order to start 3% Sodium
Chloride 1 Liter with the dose of 1ml/kg/hr via peripheral line.
Activity:
1. Determine how many mL of 0.9% Sodium Chloride and Sodium Chloride 50 mEq/20ml are
needed to make 3% Sodium Chloride 1 liter. Show your computation.
1000 ml of 3% NaCl
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Pharmacy Preceptors Guild of the Philippines
HOSPITAL PHARMACY VIRTUAL INTERNSHIP PROGRAM
CLINICAL PHARMACY – Compounding and Drug Calculation
ACTIVITY ASSIGNMENT – 22
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3. Is 3% Sodium Chloride infusion recommended to be infused via peripheral line? Please provide
reference for your answer.
- Three percent sodium chloride (3% NaCl) is a hyperosmolar agent that can be lifesaving for
patients . 3% Sodium Chloride infusion are usually recommended via central lines and not
through peripheral IV lines. However, in case CVAD is not available, several studies reveals
that it is safe to administer via peripheral vein in cases of hyponatremia in situations in
which a delay in therapy could result in neurologic complications. But still Infusions of 3%
sodium chloride is highly recommended to be given via Central IV lines. A growing number of
studies have reported relatively safe administration of 3% NaCl through a peripheral vein.
Reference: Metheny, N.A. (2021 April). Administration of 3% Sodium Chloride Via a Peripheral Vein A
Literature Review. Journal of Infusion Nursing. 44(2); 94-102. DOI: 10.1097/NAN.0000000000000420
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