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+ pulse - pulse
S. tach
2 min cpr 2 min cpr
Arrhythmia nsr
s. brady
afib/flutter
+
IVF vt/vf epi + amio + epi + amio + -
o2
Dig
βb
ccb
sxs?
monitor
pea
asystole epi - absent - epi - absent - -
amio +
chf
+ chf stable sysbp<90
cp
cpr
sob
ams
stable unstable
drugs electricity
fast+wide: amio fast=shock
fast+nar ro w : aden os in e
slow=pace
slow=atropine
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USMLE e e r m h nne s
Me est i e s: https://t.me/USMLEMe est
K p n ssr m i e s: https://t.me/USMLEK p n
Ph se i e s: https://t.me/USMLEPh se
Pi ri e i e s: https://t.me/USMLEPi ri e
P th m i e s: https://t.me/USMLEP th m
nA i s i h it : https://t.me/USMLE nA i s
Am ss r p: https://t.me/USMLEAm ss
Le t ri nk: https://t.me/USMLELe t ri
L E Me E : https://t.me/USMLE n ineMe E
KissPrep: https://t.me/USMLEKissPrep
Osmosis: https://t.me/USMLEOsmosis
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USMLE e e r m h nne s
Me est i e s: https://t.me/USMLEMe est
K p n ssr m i e s: https://t.me/USMLEK p n
Ph se i e s: https://t.me/USMLEPh se
Pi ri e i e s: https://t.me/USMLEPi ri e
P th m i e s: https://t.me/USMLEP th m
nA i s i h it : https://t.me/USMLE nA i s
Am ss r p: https://t.me/USMLEAm ss
Le t ri nk: https://t.me/USMLELe t ri
L E Me E : https://t.me/USMLE n ineMe E
KissPrep: https://t.me/USMLEKissPrep
Osmosis: https://t.me/USMLEOsmosis
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USMLE e e r m h nne s
Me est i e s: https://t.me/USMLEMe est
K p n ssr m i e s: https://t.me/USMLEK p n
Ph se i e s: https://t.me/USMLEPh se
Pi ri e i e s: https://t.me/USMLEPi ri e
P th m i e s: https://t.me/USMLEP th m
nA i s i h it : https://t.me/USMLE nA i s
Am ss r p: https://t.me/USMLEAm ss
Le t ri nk: https://t.me/USMLELe t ri
L E Me E : https://t.me/USMLE n ineMe E
KissPrep: https://t.me/USMLEKissPrep
Osmosis: https://t.me/USMLEOsmosis
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USMLE e e r m h nne s
Me est i e s: https://t.me/USMLEMe est
K p n ssr m i e s: https://t.me/USMLEK p n
Ph se i e s: https://t.me/USMLEPh se
Pi ri e i e s: https://t.me/USMLEPi ri e
P th m i e s: https://t.me/USMLEP th m
nA i s i h it : https://t.me/USMLE nA i s
Am ss r p: https://t.me/USMLEAm ss
Le t ri nk: https://t.me/USMLELe t ri
L E Me E : https://t.me/USMLE n ineMe E
KissPrep: https://t.me/USMLEKissPrep
Osmosis: https://t.me/USMLEOsmosis
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USMLE e e r m h nne s
Me est i e s: https://t.me/USMLEMe est
K p n ssr m i e s: https://t.me/USMLEK p n
Ph se i e s: https://t.me/USMLEPh se
Pi ri e i e s: https://t.me/USMLEPi ri e
P th m i e s: https://t.me/USMLEP th m
nA i s i h it : https://t.me/USMLE nA i s
Am ss r p: https://t.me/USMLEAm ss
Le t ri nk: https://t.me/USMLELe t ri
L E Me E : https://t.me/USMLE n ineMe E
KissPrep: https://t.me/USMLEKissPrep
Osmosis: https://t.me/USMLEOsmosis
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USMLE e e r m h nne s
Me est i e s: https://t.me/USMLEMe est
K p n ssr m i e s: https://t.me/USMLEK p n
Ph se i e s: https://t.me/USMLEPh se
Pi ri e i e s: https://t.me/USMLEPi ri e
P th m i e s: https://t.me/USMLEP th m
nA i s i h it : https://t.me/USMLE nA i s
Am ss r p: https://t.me/USMLEAm ss
Le t ri nk: https://t.me/USMLELe t ri
L E Me E : https://t.me/USMLE n ineMe E
KissPrep: https://t.me/USMLEKissPrep
Osmosis: https://t.me/USMLEOsmosis
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mom wants
Aneuploidy screen 1st tri
u/s nuchal trans..<3mm
path: - +
screen papp-a
Down’s Drinking 21
low high hcg
Edwards Election 18 risk risk
Patau’s pg-13 13 stop 2nd tri
-
invasive
triple quad
risk = maternal (35) +
hcg afp estriol inhibin-a
prevalence=younger women generic downs
dz
Pt: asx screen terminate edward’s
• maternal age patau
• aneuploidy
cell-free DNA 1st tri + 2nd tri
Dx: screening tool (non) combined
screen sensitivity
fetal dna
confirm test (invasive) options
maternal blood
Tx: termination - 2nd tri
sequential
genetics screen 1st tri
Cf: whites options +
hgbss: blacks invasive
invasive= fetal loss
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>20wks access-transfuse
pubs <34wks
fetal anemia
hgb
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thyroid htw
u/f/d
u/f/d path: hyper: fetal demise path: bp <140/<80
asx hypo: cretinism
screen
fevers
cva tender
pt: α -methyldopa
pt: hyper: -labetalol
+ pyelo hypo: raiu -hydralazine
sxs u/a + wbc casts
+ u/a dx: hyper: tsh, ft4 acei, arb, ccb
+ u/a + sxs + u/a hypo: tsh, ft4 diuretics
asx ptu pregnancy
tx: hyper: 2nd surg tight eclampsia
cystitis pyelo screening
bacteriuria
radio i2
ceftriaxone hypo: levothyroxine DM
* amoxicillin f/u tsh q4wks
nitrofurantoin reassess f/u: tbg, levothyroxine -before pregnancy
tmp-smx a1c <7%
cipro improved seizure
diet+exercise
path: all aed teratogens
rescreen pyelo abscess pt: epilepsy orals->insulin
u/a 10d abx 14d abx dx: clx
drain -during
ct scan tx: levetiracetam=lamotrigine
requirement insulin
u/s basal-bolus
valproate (x)
post-prandial
culture, sensitivity phenytoin (o) a1c
nitrites carbamazepine (o)
leuk esterase epi cells -post-delivery
balance
lots of wbc
>100,000 colonies insulin macrosomic
bacteria f/u: phenobarb pregnancy transposition shoulder dystocia
folate
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USMLE e e r m h nne s
Me est i e s: https://t.me/USMLEMe est
K p n ssr m i e s: https://t.me/USMLEK p n
Ph se i e s: https://t.me/USMLEPh se
Pi ri e i e s: https://t.me/USMLEPi ri e
P th m i e s: https://t.me/USMLEP th m
nA i s i h it : https://t.me/USMLE nA i s
Am ss r p: https://t.me/USMLEAm ss
Le t ri nk: https://t.me/USMLELe t ri
L E Me E : https://t.me/USMLE n ineMe E
KissPrep: https://t.me/USMLEKissPrep
Osmosis: https://t.me/USMLEOsmosis
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Ph se i e s: https://t.me/USMLEPh se
Pi ri e i e s: https://t.me/USMLEPi ri e
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AMS
JVD S3 Dx
PMI 10%
After 10% BNP <100 = CHF >500 = CHF
Xray
R L
LOAD DOE
PND * Echo EF , Dia = HTN
Crackles
LHC
ORTHOPN
Kerley B Ischemic or NOT
Abd Effusions RHC
Body pain
OFF Weight
Gain
JG Peripheral Edema
ON
Ischemic • Diet: <2g Na Ci/ d
PRELOAD Aldo ASA, Statin <2L H2O / d
NYHA
Renin Ang II CLASS <35% AICD • Weight Daily
βB 5lbs / 48 = Diuretic
NYHA ASX I Double
Ace / ARB
Etiology • Avoid NSAIDS
Exertions II Loop Diuretics
EF
BNP Dry
Edema ADLS III Spironolactone 25mg
BiDil
Cr, Hgb, K
@ REST IV
Dry Weight Milrinone
Last Weight Dobutamine LVAD Transplant
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Preload SVR
WARM COLD Diuresis = DOSE
a 2.5x oral as IV
Normal Low-Flow 3L Day 1
DRY -1L / day
Vasodilation
10% ADHF b gtt = Bolus
PL Diuresis
IV Enalapril
Afterload Cardiogenic Vasodilation
WET Overload Shock IV Hydralazine
inotropes
70% ADHF 20% ADHF Dobutamine
inotropes
SVR Milrinone
(wet)
DRY/WET = PRELOAD = VOLUME WARM / COLD = SVR
PRE
LOAD
Afterload (SVR) Hx Phys Hx Phys
DOE * JVD / HJR Fatigue Wrists / Ankles
certain Orthopnea Edema Somnolence Narrow Pulse
PND Crackles AMS Pressure
weight gain Kerley B Pulsus
U/S Alternans
CONT +1 - Abd Pain Effusions
βB? - Xrays
- BNP 90° - 60° - 30° - 0°
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D DM 1
2+ Anti
S CVA/TIA 2
VASC Coagulate
CAD, PVD, etc. 1
Option? Dabigatran
warfarin NOAC Anpixaban
Rivaroxaban
No Bridge No Bridge
Anti Coagulation? Anti Coag x 1 Month INR 2-3 NO Goal
if shocked Labs NO Labs
Diet NO Diet
Reversal NO Reversal
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Identification Treatment
Day 0 1 2 3 4 5
PT: Sputum Steroids
IV
Methylpred
PO
Prednisone
Dyspnea 125 mg x 1 40mg
q4H q6H q6H MDI
ER Tried already Inhalers
Duonebs + PrN PrN
q6H prn
Doxu Po
Abx IV Azithro Abx
Hx: COPD (PFTs) PaO2 < 55
6-min Spo2 < 88%
Pack-years O2 88 - 92 %
walk
Home O2 Chronic
# inhalers Meds X
Intubation Hx
Labs: Co2 (ABG) Bipap
Bicarb (BMP)
pH + Co2 (Baseline) ET
pH + Co2 Exacerbation
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CTEPH
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Ph se i e s: https://t.me/USMLEPh se
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Page 265
T Wide Blocks
ke d QRS Brady
Pea
HYPO K 275 mEq Hyper K EKG K
Magnesium
t
K 0.1 Ig IV
Stabilize IV Calcium
3.0 - 4.0 10 mEq 100 (Mins)
2.5 - 3.0 15 mEq 75 Temporize IV Insulin ( 10 Units)
(4 hrs) +
2.0 - 2.5 20 mEq 100
D50
PIv: 10 mEq/hr (Burns)
CIv: 20 mEq/hr (Die)
Eliminating Diuretics
PO: 20/40, elixir/pill Kayexalate
Dialysis
40 mEq KCl IV q4H x3 (120)
AND
40 mEQ KCl PO QAC x3 (120)
BMP @2:00
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UGIB
Hematemesis
Actions Ng
Lavage?
GI Bleed
Embolize Colon
cirrhotic 6 Octreotide βB
Meh
Melena 7 Ceftriaxone ?
Melena ICU? 3pRBC + 1 plt + 1 FFP
• Shock MAP = CO X SVR
• Orthostatics
• Rapid Transfusions HR x SV
Stable Reassuring Velocity PL x CONT
Hematochezia • BUN:Cr > 35
A C
LGIB • Hgb (<10)
• Vital Signs
B D
t
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NovoLog (Aspart)
HumaLog (Lispro) Insulin Insulin Insulin Insulin
Lantus (glargine) bG bG bG bG
l Long Eat Eat Eat Sleep
pr andia Acting
Levenir (Detemir)
Chronic I II III IV
Liver Compensated decompensated Death
DZ Decades Cirrhosis 15 yrs Cirrhotic 1.5 yrs
IV Fulminant Hepatic
Failure
HCC
Acute Liver Dz
Hypersplenism Plt, WBC AAST, ALT 1000s
B = vaccine Synthetic Dysfxn Alb, INR, AST:ALT 2:1
* V iral Hep Hepatopulmonary
Syndrome Muscle Wasting Acetaminophen
C = Cure
Wilson’s Spider Angiomata, palmar erythema Acute Viral Hep
Caput Medusae Autoimmune
H emochromatosis
Portopulmonary Vasodilation
A utoimmune HTN AFlatoxin
Cirrhosis Splanchnic La.
P BC Map Co
A clot (Budd-Chiari)
P SC Hypotension
Liver Dysfxn II Portal HTN Hyperdynamic Circulation
* E tOH Jaundice Hepatic Varices Variceal Hemorrhage III Healthy Liver
* N ASH Encephalopathy Ascites Refractory Ascites INRD 1.5
Hepatorenal Syndrome Hep. Enceph
S omething
else SBP
Transplant
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Ascites Varices
Cirrhosis
EGD Pre
propanolol
Bleed
NO > Small Nadolol
Carvedilol
Portal Alb RAAS q2-3y Small EVL + NSBB
HTN
NSBB Post
H O Preload EVL + NSBB Bleed
Alb <2g NACi/d
TIPS <2L H2O/d NH3 = HE EGD w/i 12 hrs Octreotide
Ceftriaxone
Intra
Spironolactone 100 Varices Bleed
Blakemore Tube
MELD <15 Furosemide 40 NO BB Hgb <7
TIPS - sick
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CR Diag ≥250
ANYTHING fever Tap SBP
Sepsis AMS PMNS
Ceftriaxone
Na T. Bili Pain Dyspnea
INR Fluid Variceal Hemorrhage 2° PPx
* MELD Cr CMP Octreotide No βB
Norfloxacin 500cc 5% Alb
INR q8H Day 1 + Day 3
Ceftriaxone Hgb <7
* Encephalopathy CBC
Intravascular
Total Body 500cc 5% Alb Blakemore Deplete Renin Ang II
Fluid intravascular Early EGD - EVL OFF
Aldo
Variceal Renal
u/A, Umicro Hemorrhage Vaso
ON
Na
CXR HRSI Constriction
I nfxn Pan Cx Blooc CX H2 O
Cr x2 OR SBP ADH
SBp = Diag Tap CrCl 1/2
Bleed CBC, Variceal = GI
And Hyperdynamic Splanchnic UNA < 10
W/i Two weeks Circulation Vasodilation
Med -most common
Compliance -last considered Octreotide
Die FIX Midodrine
EVERYTHING ELSE
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Hep C
Hepatopulmonary HCC Cirrhosis HIV
Hep B
Bubble Study Hep B S Cirrhosis
O2 O2 Screening: U/s + AFP
Small
3-6 = HPS Confirm: triple Phase CT
1-2 = PFO
x
Large = Nrml
C Milan Early Art Late Art Venous
Platypnea 1 <5cm
washout
3 <3cm
Portopulmonary HTN RHC Cure HCC Time
+
vasodilator
Child
A Pugh C
>50 <35
one Hospice
Everything
Else
Excluded Transplanted
small Invasion
Congestive
DIE Sorafenib
Staging
Sildenafil
Hepatopathy Inside
Milan
Outside
Milan
Bosentan Portal Liver
Alprostadil Pressure Rdy? No TACE
yes
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CPAP Bipap
K x [con] x SA
NC Venti
Face Tent NRB ET Tube J=
HFNC t x size
1-6 LPM 6-10 CPM 10-15 LPM 20-40 LPM SA
20%-40% 40-60% 60-80% 100%
O2 FiO2
P CPAP = PEEP P Bipap SpO2 O2 Peep
0
__ 10
__ ABG
PSOP
5 5
5
PEEP
O2 ABG CO2 MV = TV x RR
t Co2 t
t
Assidse Con
CHF PSOP
Mo SIMV trol COPD
Bipap PRVC Mod
e
CPAP VC PRVC
Ppeak / Pplateau
O/5 SBT PC PEEP
ET TUBE Teens
FiO2 Ppeak
Low TV OK 20s
Fi P TV RR
T-piece RR
30s
P xx 40s
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Frank : MAP
< 65 Distributive Sepsis
Shock
MAP = CO x SV R
Anaphylaxis
Occult : Relative
Shock HoTN, Lactate Spinal Trauma
(TONE)
Too Fast Anesthesia
Shock : HR > 1 = Addison’s (Hx)
__
index SYSBP
70 / 60
(ECG) HR x SV Wide pulse pressure
narrow
Too Slow 70 / 20
Sys pulse
pressure
Cold PL x CONT
WARM + Shock
+
Shock (Ivf) vol : D/D/D/H MI BNP
TONE
Whomp CHF TROP
Sys PTX Echo
RV
PT
obst: - TONE = SVR
LV PE DIA
Sys
Distributive
120
___
Cardiogenic 40 TONE
80
Hypovol 80
Obstructive
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Sepsis inoconstrictors
MAP = CO x SVR Spinal
Anesthesia vasoconstrictors
Too HR x SV Anaphylaxis
β1 β2
α1
PL x CONT
Volume VOL : D/D/D/H MI β1
CHF Vasoconstriction inotrope vasodilation
Obst : PTX
inotropes
PT α1 β1 α1 β1 β2
Alleviate PE
Vasoconstrictors inocontstrictor inodilators vasodilator
vasopressin Norepinephrine Milrinone Nicardipine
phenylephrine Dopamine Dobutamine NO
* epinephrine Esmolol
Sepsis CHF
HTN
Energy
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ICU Vasopressors
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2 min
VENT
C C
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Proning
Homogeneity O2 Recruited
Derecruitment
Loss of
Homogeneity
PEEP
Resistance
TNF-α 16:8 Prevent
Derecruitment
IL-1
PAralyze
4-6 cc/kg
Ideal
Body Weight High PEEP =
Low TV = Prevent
Barotrauma
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GI Cocktail
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ABG - RT
met Resp CXR - Rad
acid Alka
12-LEAD - ECG
Bad
No Blood Blood BNP - RN / Lab
“Anemia” Carboxy
Meth
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Epigastric
Pain
Heart Esophagus
RUQ u/s Pericardium Stomach CT
Aorta Pancreas
Somatic Visceral Neuropathic Lung Trachea LUQ
Diaphragm Lung
Liver Diaphragm
Obstructed GB Spleen
Stretched Referred
P B L
Inflamed M A U
D N
C
Obstructive Inflammatory Perforation Ischemia H
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Type Hxt Pt Dx Tx
W asovagal Situat ional Carot id Tilt BB
Viscer al Recur rent Massa ge table
Baror ecepto rs Prodr ome Asysto le, 50
Orthostatics IVS
LOC Psych ogeni c Orthostatic
O rthostatic
Seizur e Syncope VOL : D/D/D/H
Jerk >20 <10 ANS: Old, Parkinson’s Exert ional Murm ur Echo Surge ry
B U
Post
* ictal >5 min <1 min M echanical Sudde n onset - Holte r -
Gradual rapid Cardia c Prodr ome
Prodrome Aura Vasovagal A rrhythmia Loop
Event
N eurogenic rare FND
Carot id u/s u/s
CTA/m ra
Tongu e Biting
Fallin g Face- Palm -
Loss of P sych
Na, Ca
Bowe l/Bla dder E -lyt es -
- - BMP
K, Mg
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CvA
Bleed
LAMBERT-EATON Cancer
Pml MYOSITIS
MS Dermato Statin Infxn
TM Polymyo Fungal TB Bacterial
MYASTHENIA GRAVIS ALS IBmyositis
Trauma
Spinal Stenosis
Spinal Abscess
Polio
West-Nile DM R emote cancer
DlO2 = CO x Hgb x %Sat
A lcohol A utoimmune
N utrition, B12 P orphyria
HR x SV
Guillain-Barré I nflammatory
PL x CONT Ng Mg T rauma, Radiculopathy S yphilis
H ereditary, CMT TB
AMS E-Lytes WEAK
E nvironmental, Lead
Ca K
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J=K(H-O) x Ascites
paracentesis
“INFLAMMATION” “HYDROSTATIC” “OSI”
ARDS Sepsis
pancreatitis
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Temp encephalitis
H tn / Hna
epatic
inflam I nfxn UTI
E -lytes ca Porphyria
S epsis
S troke
non T rauma Acidosis bg
inflam Opiates E ndocrine ft4,t sh
P sych addison’s
I ntoxication / wIthdrawal
S eizure
O / co
2 2
U remia
cbc, bmp, lfts, utox, abg, tsh
ct scan
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CXR EGD GI
CT PULM
BRONCH
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Am ss r p: https://t.me/USMLEAm ss
Le t ri nk: https://t.me/USMLELe t ri
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Page 288
inpt fever
- blood cx x 2
- u/a, umicro
- cxr
A bscess 3 thermostat 2 AC 1 environment
thalamic heat stroke - think
e ndocardit n ms
i ndwelling infxn stroke heat exhaustion
o steo dvt/pe thyroid malignant hyperthermia
heat exposure
u TI MI storm Serotonin syndrome
clots CVA
ALI
leukemia
lymphoma the meds
cancer
sle
ra
AI seroneg
monoartic
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1 3 2
Cr
Vol Diurese
Pre-renal
Vol Volume
RAS/FMD
i”
U/S
“OS sis post-renal obstructing
rho is Hydro Foley
Cirphrossis
Ne stro
Ga Hydro
intra-renal
CHF
Vol : D/D/D/H
1 pre = Poor Perfusion 3 GN 2 post = obstruction Call Renal c
AIN Stones - Renal Function
CHF Overload
intra deplete
ATN Cancer - U/A, UMicro
Cirrhosis but overload NEPH- Neurogenic - U creatinine
Vol Depleted NEPHRI- Prostate - U Na, K, Cl
RAS/FMD Special
- Spot Protein
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DAPT
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Laryngo
Dysph agia
ENT
oropharyngeal Initiation
Tumor
oropharyngeal Esophageal
Esophageal
CvA food AND food THEN
GI TM MS
vagus
Liquid Liquid
Endo Speech Therapy
pharyngogram motility Mechanical
Barium Barium
EGD EGD
NG Tube Manometry
PEG Tube GI
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1 1-3 3+
Mono oligo Poly
V
Hep C, HIV
OA gonorrhea I
(A) Trauma (A) Infectious R EBV, CMV
NOT parvo
U
Gout S
High Low (A) crystal pseudo
gout
S ero SLE
Sudden insidious S ero
onset Acuity RA
+ P soriatic S yphilis
Loss of Toxicity Weight A nk Spond S arcoid
fxn Loss Sero I BD S till’s
R eactive (A) S epsis
Fever Temp
Markers Markers
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High Rez CT
CXR OLD = COPD
DPLD PFT
CTEPH WHO
Echo CTA, v/q
EPAP CHF - LV 1:
Echo
R L
OSA
Sleep 2: Pulm Venous
Primary Study High Rez Regular Cardiac Dysfxn
Pulmonary
Boo! vasodilate hypertension
RHC CCB
c CCB
Yay! 3: Intraparencyhmal
ANA, RF, ssA, ssB
Experimental
Bosentan HIV, Hep Panel
4: Pulm Art
Alprostedil TSH Clots
Revatio (Sildenafil)
5: Other
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Cough
CXR
1 fails Asthma
Big 3 GERD 1° Pathology
PND
Pulm
Empire
Tx
All Fail
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KissPrep: https://t.me/USMLEKissPrep
Osmosis: https://t.me/USMLEOsmosis