Determining Medical Fitness To Operate Motor Vehicles: CMA Driver's Guide
Determining Medical Fitness To Operate Motor Vehicles: CMA Driver's Guide
Determining Medical Fitness To Operate Motor Vehicles: CMA Driver's Guide
medical fitness
to operate
Dr. Katherine Kohle
Practicing physician
motor vehicles
CMA Driver’s Guide
9th edition
We have a leadership
course for that
As a physician, you are faced with many day-to-day
challenges in your role as a care-giver, collaborator,
leader. From communicating difficult information to
leading change in the health care system, you have
endless reasons to make your development a priority.
cma.ca/pli
Martin Roos
PLI participant
CMA member
© Joule Inc. 2017
Please note that Joule Inc. is a member of Access Copyright, The Canadian Copyright Licensing Agency
(formerly known as CANCOPY). As such, we have an agreement in place with ACCESS to grant to
organizations and individuals, on our behalf, permission to make photocopies from our publications.
Should you wish to pursue this request, we ask that you contact ACCESS COPYRIGHT, THE CANADIAN
COPYRIGHT LICENSING AGENCY, 320 - 56 Wellesley Street West, Toronto ON M5S 2S3;
tel 416 868-1620; 800 893-5777; fax 416 868-1621 or visit: www.accesscopyright.ca.
Disclaimer: This guide is not a substitute for medical diagnosis, and physicians are encouraged to
use their best clinical judgment to determine a patient’s medical fitness to drive. The naming of any
organization, product or alternative therapy in this book does not imply endorsement by Joule Inc. or
the Canadian Medical Association, nor does the omission of any such name imply disapproval by Joule
Inc. or the Canadian Medical Association. Neither Joule Inc. nor the Canadian Medical Association
assumes any responsibility for liability arising from any error in or omission from the book, or from
the use of any information contained in it.
Contents
Acknowledgements . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . xiv
Scientific Editorial Board . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . xiv
Contributing authors . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . xiv
Contributors . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . xv
CMA staff . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . xv
Joule staff and contractors . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . xv
Section 1: Introduction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1
1.1 A guide for physicians . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1
1.2 Functional assessment . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1
1.3 Medical standards for fitness to drive . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2
1.4 Methods . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2
1.5 The physician’s role . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3
1.6 Public health . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 4
1.7 Levels of medical fitness required by the motor vehicle licensing authorities . . . . . . . . . . . . . 4
1.8 Driver’s medical examination report . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 5
1.9 Physician education on driver evaluation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 6
1.10 Payment for medical and laboratory examinations . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 6
1.11 Classes of drivers’ licences and vehicles . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 6
1.12 Contact us . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 7
Section 2: Functional assessment — emerging emphasis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 8
2.1 Overview . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 8
2.2 Standards . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 8
2.3 Assessment . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 9
2.3.1 Office assessment . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 9
2.3.2 Functional assessment . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 9
Section 3: Reporting — when and why . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 11
3.1 Overview . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 11
3.2 Reporting . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 13
3.3 Patient’s right of access to physician’s report . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 13
Section 4: Driving cessation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 16
4.1 Overview . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 16
4.2 Voluntary driving cessation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 16
Contents v
Section 8: Dementia and mild cognitive impairment . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 35
8.1 Overview . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 35
8.2 Canadian Dementia Guidelines . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 35
8.3 Reporting according to stage of dementia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 36
8.4 Red flags — the 3Rs . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 36
8.5 Assessment of non-cognitive factors . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 37
8.6 Cognitive screening tools . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 37
8.6.1 Use tests in the context of more detailed approaches . . . . . . . . . . . . . . . . . . . . . . . . . . . . 39
8.7 When fitness to drive remains unclear . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 39
8.8 Counselling patients with dementia who can still drive safely . . . . . . . . . . . . . . . . . . . . . . . . . . 40
8.9 Disclosure of unfitness to drive . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 40
8.10 Follow-up after loss of licensure . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 40
8.11 Countermeasures . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 40
Section 9: Sleep disorders . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 41
9.1 Overview . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 41
9.2 Assessment . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 41
9.3 Obstructive sleep apnea (OSA) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 42
9.3.1 Driving recommendations for patients with OSA . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 43
9.4 Narcolepsy . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 43
9.4.1 Driving recommendations for narcoleptic patients . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 44
9.5 Other sleep disorders . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 44
Section 10: Psychiatric disorders . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 45
10.1 Overview . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 45
10.2 Functional impairment . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 46
10.3 Assessing fitness to drive . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 47
10.4 Specific disorders . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 47
10.4.1 Schizophrenia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 47
10.4.2 Personality disorders . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 48
10.4.3 Depression and bipolar disorder . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 48
10.4.4 Anxiety disorders . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 49
10.4.5 Psychotic episodes . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 50
10.4.6 Attention deficit/hyperactivity disorder (ADHD) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 50
10.4.7 Aggressive driving . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 52
10.5 Psychoactive drugs . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 53
Contents vii
12.4 Exceptional cases . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 66
Addendum 1: Testing procedures . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 66
A1.1 Visual acuity . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 66
Addendum 2: Medical conditions and vision aids for driving . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 68
Section 13: Auditory and vestibular disorders . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 70
13.1 Overview . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 70
13.2 Hearing . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 70
13.2.1 Standards . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 70
13.2.2 Hearing assistive devices . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 70
13.3 Vestibular disorders . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 71
13.3.1 Acute unilateral vestibular dysfunction — single prolonged episode . . . . . . . . . . . . . . 71
13.3.2 Recurrent unilateral vestibular dysfunction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 71
13.3.3 Chronic bilateral vestibular hypofunction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 71
Section 14: Cardiovascular diseases . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 72
14.1 Overview . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 72
14.1.1 Details regarding these and other recommendations can be found
in the full report. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 72
14.2 Coronary artery disease . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 73
14.2.1 Acute coronary syndromes . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 73
14.2.2 Stable coronary artery disease . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 74
14.2.3 Cardiac surgery for coronary artery disease . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 74
14.3 Cardiac rhythm, arrhythmia devices and procedures . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 74
14.3.1 Ventricular arrhythmias . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 74
14.3.2 Paroxysmal supraventricular tachycardia,
atrial fibrillation or atrial flutter . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 75
14.3.3 Persistent or permanent atrial fibrillation or atrial flutter . . . . . . . . . . . . . . . . . . . . . . . 75
14.3.4 Sinus node dysfunction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 75
14.3.5 Atrioventricular and intraventricular block . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 75
14.3.6 Permanent pacemakers . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 76
14.3.7 Implantable cardioverter defibrillators . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 77
14.3.8 Other . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 78
14.4 Syncope . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 78
14.5 Valvular heart disease . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 79
14.5.1 Medically treated valvular heart disease . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 79
14.5.2 Surgically treated valvular heart disease . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 80
Contents ix
18.1 Overview . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 96
18.2 Assessment . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 96
18.3 Chronic obstructive pulmonary disease (COPD)
and other chronic respiratory diseases . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 96
18.4 Permanent tracheostomy . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 97
Section 19: Endocrine and metabolic disorders . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 98
19.1 Overview . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 98
19.2 Diabetes mellitus . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 98
19.3 Non-diabetic renal glycosuria . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 99
19.4 Non-diabetic hypoglycemia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 99
19.5 Thyroid disease . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 100
19.6 Parathyroid disease and other calcium disorders . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 100
19.7 Pituitary disease . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 100
19.7.1 Posterior deficiency . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 100
19.7.2 Anterior deficiency . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 100
19.7.3 Acromegaly . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 100
19.7.4 Pituitary tumour . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 100
19.8 Adrenal disease . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 101
19.8.1 Cushing’s syndrome . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 101
19.8.2 Addison’s disease . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 101
19.8.3 Pheochromocytoma . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 101
Section 20: Renal diseases . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 102
20.1 Overview . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 102
20.2 Dialysis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 102
20.2.1 Hemodialysis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 103
20.2.2 Peritoneal dialysis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 104
20.3 Renal transplant . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 104
Section 21: Musculoskeletal disabilities . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 105
21.1 Overview . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 105
21.2 Assessment . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 105
21.2.1 Injury to or immobilization of a limb . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 106
21.2.2 Loss of limbs, deformities and prostheses . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 107
21.2.3 Arthritis, other musculoskeletal pain and ankylosis . . . . . . . . . . . . . . . . . . . . . . . . . . . . 108
21.2.4 Injury to or immobilization of the spine . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 108
21.2.5 Post-orthopedic surgery . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 109
Contents xi
26.8.1 Blood pressure . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 122
26.8.2 Valvular heart disease . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 122
26.8.3 Congenital heart disease (CHD) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 122
26.8.4 Cardiac arrhythmia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 122
26.9 Cerebrovascular disorders . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 123
26.10 Other vascular disorders . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 123
26.11 Nervous system . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 123
26.12 Respiratory diseases . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 124
26.13 Endocrine and metabolic disorders . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 124
26.14 Renal system . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 125
26.15 Musculoskeletal system . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 125
26.16 Psychiatric disorders . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 125
26.17 Tumours . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 126
26.18 HIV infection and AIDS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 126
26.19 Drugs . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 126
26.20 Contacts . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 127
Section 27: Railway . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 129
27.1 Overview . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 129
27.2 Railway Safety Act . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 130
27.3 Reporting . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 130
27.4 Medical fitness . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 130
27.5 General considerations . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 130
27.6 Specific issues . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 132
27.7 Resources . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 132
27.8 Contacts . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 132
Appendix A
Bibliography . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 134
Appendix B
Fitness to drive issues and risk management
Message from the Canadian Medical Protective Association (Revised 2012) . . . . . . . . . . . . . . . . . 151
Appendix C
The CAGE questionnaire . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 154
Appendix D
Alcohol use disorders identification test: Interview Version (AUDIT) . . . . . . . . . . . . . . . . . . . . . . . 155
Contents xiii
Acknowledgements
Scientific Editorial Board
Dr. Jamie Dow, Editor-in-Chief, Quebec
Dr. Christopher Simpson, Kingston, Ontario
Dr. Frank Molnar, Ottawa, Ontario
Dr. Ian Gillespie, Victoria, British Columbia
Contributing authors
Canadian Cardiovascular Society (Cardiovascular diseases)
Canadian Medical Protective Association (Reporting, Appendix B)
Canadian Ophthalmological Society (Vision)
Dr. Dan Bergeron (Vision)
Dr. Edward Brook (Aviation)
Dr. François Cabana (Musculoskeletal disabilities)
Dr. Bonnie Dobbs (Driving cessation)
Dr. Jamie Dow (Introduction, Functional assessment, Anesthesia and surgery, Seatbelts
and airbags, Motorcycles and off-road vehicles, Miscellaneous conditions)
Dr. Hillel Finestone (Cerebrovascular diseases [including stroke])
Dr. Serge Gauthier (Nervous system)
Dr. Charles George (Sleep disorders)
Dr. Ian Gillespie (Alcohol, Drugs, Psychiatric illness, Traumatic brain injury)
Dr. Roger Goldstein (Respiratory diseases)
Dr. Raju Hajela (Alcohol, Drugs)
Dr. George Lambros (Railway)
Dr. Thomas Lindsay (Vascular diseases)
Dr. Shawn Marshall (Traumatic brain injury)
Dr. Frank Molnar (Aging, Dementia and mild cognitive impairment)
Dr. Lorne Parnes (Auditory and vestibular disorders)
Dr. Mark Rapoport (Dementia and mild cognitive impairment)
Rebecca Taylor (Dementia and mild cognitive impairment)
Dr. David Salisbury (Aviation)
Dr. Sabin Shurraw (Renal diseases)
Contributors
Dr. Russell Barkley (Psychiatric illness)
Dr. Laurence Jerome (Psychiatric illness)
CMA staff
Jean Nelson, Senior Legal Counsel
Acknowledgements xv
Section 1:
Introduction
1.1 A guide for physicians
Following the example set by the Canadian Medical Association (CMA) guide on the
evaluation of fitness to drive since publication of the first edition in 1974, this 9th edition
continues to provide current, practical information for health professionals involved in
the determination of medical fitness to drive.
This edition incorporates the Diagnostic and Statistical Manual of Mental Disorders, 5th
edition (DSM-5) in the sections on alcohol, drugs and psychiatric disorders. The section
on dementia and mild cognitive impairment has been completely revised, and most of
the other sections have had minor changes. The revisions reflect the aim to maintain the
guide’s currency as the physician’s principal source of up-to-date information on medical
fitness to drive.
The authors have continued to reinforce the scientific basis for the guide’s
recommendations by using CMA’s and their own resources to search the literature for the
most recent information on the effects of medical conditions on driving fitness. One result
of this effort is greater discussion of attention deficit/hyperactivity disorder (ADHD) in the
section on psychiatric disorders. A new element is the effect of ADHD on crash risk, which
has been the subject of several articles since the publication of the 8th edition.
Adopting levels of evidence for these practice guidelines is proving to be a bigger
challenge than we believed to be the case when we described our intention to do so
in the introduction to the 8th edition. Consequently, we are proceeding on a section-
by-section basis. In this edition the sections on psychiatric disorders and on dementia
and mild cognitive impairment were the subject of intensive literature reviews. Other
sections will follow in subsequent editions, although all of the section authors have
conducted literature searches and provided bibliographies in Appendix A.
Like the 8th edition, the 9th edition will continue to be primarily a digital document.
Consequently, if you are using a printed version of the guide more than a year after its
publication, you are advised to check the online version for updates.
1.4 Methods
A Scientific Editorial Board composed of 3 member physicians and a physician editor-in-
chief continued the work they had begun with the production of the 8th edition. Where
possible, an evidence-based approach was used, although medical standards for driving
will always contain some consensus-based recommendations, since some situations do
not lend themselves to an evidence-based approach. For example, the vision section
remains consensus-based, as no cutoff points for visual acuity or visual fields based on
crash risk have been established.
However, the evidence for medical factors in crash risk is improving. The Scientific
Editorial Board was aided in the preparation of this guide by a review of recent scientific
reports for each section. Interested readers are referred to a study undertaken by the
Monash University Accident Research Centre, entitled Influence of Chronic Illness on
Crash Involvement of Motor Vehicle Drivers, 2nd edition, November 2010, which is the
most complete and detailed review of the evidence supporting medical standards for
Introduction 2
drivers at the time of publication of this guide. The 2009 National Highway Traffic Safety
Administration's publication Driver Fitness Medical Guidelines is another useful publication
that contains both extensive references and an analysis of the literature. In addition, a
“risk of harm” formula that was introduced in the 7th edition, to support the Canadian
Cardiovascular Society recommendations on fitness to drive (section 14), has been
retained in this edition. However, the recommendations remain mainly empirical and
reflect the fact that the guidelines presented here are based on the consensus opinion of
an expert panel supported by a careful review of the pertinent research and examination
of international and national standards, as well as the collected experience of a number
of specialists in the area. They are intended to impose no more than common sense
restrictions on drivers with medical disabilities. This guide is not a collection of hard-and-
fast rules, nor does it have the force of law.
Introduction 4
The motor vehicle licensing authorities require a higher level of fitness for commercial
drivers who operate passenger-carrying vehicles, trucks and emergency vehicles. These
drivers spend many more hours at the wheel, often under far more adverse driving
conditions, than drivers of private vehicles. Commercial drivers are usually unable to select
their hours of work and cannot readily abandon their passengers or cargo should they
become unwell while on duty. Commercial drivers may also be called upon to undertake
heavy physical work, such as loading or unloading their vehicles, realigning shifted loads
and putting on and removing chains. In addition, should the professional driver suffer
a collision, the consequences are much more likely to be serious, particularly when the
driver is carrying passengers or dangerous cargo. People operating emergency vehicles
are frequently required to drive under considerable stress because of the nature of their
work. Inclement weather, when driving conditions are less than ideal, is often a factor.
This group should also be expected to meet higher medical standards than private drivers.
It should also be borne in mind that operators of heavy machinery, such as front-end
loaders, may hold a Class 5 (private vehicle) licence, rather than the higher classes of
licence normally required for commercial drivers. Alternatively, a patient with this class
of licence may be a commercial traveller who drives thousands of kilometres a week
in an automobile.
Introduction 6
1.12 Contact us
This guide is produced as a service to CMA members. However, the CMA and Joule does
not have the capacity to comment on or respond to questions related to clinical issues
arising from the work of the content experts.
Physicians who have comments and suggestions about the guide’s recommendations
are invited to contact the CMA and Joule at driversguide@cma.ca or toll free
at 888-855-2555.
Alert
Medical standards for drivers often cannot be applied without considering the functional
impact of the medical condition on the individual.
All Canadian jurisdictions have policies in place that allow individuals the opportunity to
demonstrate that they are capable of driving safely despite the limitations implied by a
diagnosis. Criteria may vary among jurisdictions.
2.1 Overview
Historically, determining medical fitness to drive was based solely on a medical office
examination and a diagnosis. However, recent court decisions have recognized that a
driver’s ability to accommodate and function with a given medical condition varies with
the individual.
These court decisions have also established the right of individuals to be assessed
individually for their ability to drive safely. A functional assessment, which is a structured
assessment of the individual’s ability to perform the actions and exercise the judgment
necessary for safe driving, often including a road test, takes this individual variation into
account. Functional assessments are usually administered by occupational therapists,
although some jurisdictions may have driving rehabilitation specialists who can perform
on-road assessments. Some jurisdictions perform their own on-road assessments of
driving fitness but these tests are usually less comprehensive than those performed
by occupational therapists. In particular, only occupational therapists can assess the
requirements for modifications to vehicles that are needed to accommodate drivers with
a physical disability.
A driver with a medical condition that can compromise cognitive or motor skills may
require a functional assessment to determine fitness to drive. Any compromise of the
ability to perform daily activities or of the driver’s autonomy should trigger some sort of
functional driving assessment.
Functional assessments may be available only in urban centres and may be difficult to
arrange for patients in rural areas.
2.2 Standards
Canadian jurisdictions are working to develop and apply standards that permit individual
assessment of f unctional capabilities of drivers with medical conditions that may
affect driving.
_____________________________________________________________________________
* https://www.find-an-ot.ca/
2.3 Assessment
2.3.1 Office assessment
Physicians in a medical office setting can assess their patients’ fitness to drive
when the patients are clearly either capable or incapable of driving. This guide
provides information to assist with those decisions. In less clear-cut situations,
it may be necessary for the physician to employ other means of testing to
perform a functional assessment. This usually involves on-road testing.
It should be emphasized that, with the exception of temporary restrictions
for short-term medical situations, the physician is not required to determine
whether a licence will be granted or suspended. The physician’s responsibility is
to describe the situation, and the licensing authority will make a decision based
on the physician’s observations, other available information (such as police
reports) and its interpretation of the regulations.
Alert
Physicians have a statutory duty to report patients whom they believe to be unfit to
drive to the relevant provincial or territorial motor vehicle licensing authority. This duty
may be mandatory or discretionary, depending on the province or territory involved.
This duty to report is owed to the public and supersedes the physician’s private duty
with regard to confidentiality.
3.1 Overview
All provinces and territories impose a statutory duty on physicians relating to the
reporting of patients deemed unfit to drive. This duty may be mandatory or discretionary,
depending on the jurisdiction (Table 1).† The duty to report prevails over a physician’s
duty of confidentiality. Section 35 of the CMA Code of Ethics affirms the notion that
physician–patient confidentiality may be breached when required or permitted by law:
Disclose your patients’ personal health information to third parties only with their
consent, or as provided for by law, such as when the maintenance of confidentiality
would result in a significant risk of substantial harm to others or, in the case of
incompetent patients, to the patients themselves. In such cases take all reasonable
steps to inform the patients that the usual requirements for confidentiality will
be breached.
_____________________________________________________________________________
*This section is meant for educational purposes, as a guide to physicians on reporting of patients assessed to be unfit
to drive. It is not meant to replace legal counsel. Unless specified, this section refers to fitness to drive motor vehicles.
†Pilots, air traffic controllers and certain designated railway workers are governed by federal legislation that requires
the reporting of certain individuals in these transportation industries who have a medical condition rendering them
unfit to perform their duties. These reporting obligations are discussed in separate sections of this guide (sections 26,
Aviation and 27, Railway). The marine working environment is challenging, with safety-critical responsibilities and
the presence of many hazards including a strenuous workplace, unique living conditions, unpredictable weather and
potential emergency duties. Seafarers must be able to live and work in close contact with each other for long periods.
The difficulties of this environment can be magnified when medical care is not immediately accessible when needed.
For this and other reasons, since 2001, the Canada Shipping Act requires physicians and optometrists to report to
Transport Canada Marine Safety and Security without delay when they have reasonable grounds to believe that a
seafarer has a medical or optometric condition that is likely to constitute a hazard to maritime safety.
This same law requires certificated seafarers to inform their caregivers of their safety critical role. Further
information can be found online at www.tc.gc.ca/eng/marinesafety/mpsp-training-examination-certification-
medical-2058.htm or contact Marine Medicine at 866 577-7702 for assistance.
* Used with the permission of the Canadian Medical Protective Association (CMPA)
†Information in this column is subject to the access-to-information legislation of the respective province or territory.
‡Pending legislation in British Columbia will change the province from a mandatory reporting province to a hybrid
mandatory/discretionary reporting province.
Note: MD = physician.
Driving cessation
Alert
4.1 Overview
Driving plays a central role in the daily lives of many people, not only as a means of
meeting transportation needs, but also as a symbol of autonomy and competence.
The prerogative to drive often is synonymous with self-respect, social membership and
independence.
Driving cessation can result from a gradual change in driving behaviour (i.e., restrictions
leading to driving cessation), a progressive illness (e.g., dementia) or a sudden disabling
event (e.g., a stroke). Some drivers voluntarily stop driving; for others, driving cessation
is involuntary. Gradual, voluntary driving cessation is more common than sudden driving
cessation. However, the decision to stop driving is often complex and affected by a
number of factors.
Driving cessation 16
• Transportation support — drivers who have transportation support (i.e., from family,
friends, organizations) are more likely to stop driving than drivers without
such support.
These general factors can assist physicians in anticipating who may be more comfortable
giving up driving privileges when it becomes medically advisable to stop driving.
Driving cessation 18
misses) can be helpful. Discuss the risks of continuing to drive with the patient and
family members.
• Emphasize the need to stop driving, using the driving assessment, if available, as the
appropriate focus.
• Often the patient will talk about his or her past good driving record. Acknowledge
that accomplishment in a genuine manner, but return to the need to stop driving.
Sometimes saying “medical conditions can make even the best drivers unsafe” can
help to refocus the discussion.
• It is common for drivers, especially those who are older, to talk about a wide range of
accomplishments that are intended, somehow, to show that there could not be a
problem now. Again, acknowledge those accomplishments, but follow with “Things
change. Let’s not talk about the past. We need to focus on the present” to end that
line of conversation and refocus the discussion.
• Ask how the person is feeling and acknowledge his or her emotions. Avoid lengthy
attempts to convince the person through rational explanations. Rational arguments
are likely to evoke rebuttals.
• It is likely that emotions and feelings of diminished self-worth represent a real issue
behind resistance to accept advice or direction to stop driving. Explore these feelings
with empathy. A focus on the feelings can deflect arguments about the evaluation
and the stop-driving directive.
• Ask the patient what he or she understands from the discussion. It may be important
to schedule a second appointment to further discuss the patient’s response and
explore next steps.
• Document all discussions about driving in the patient’s chart.
• To assist patients in staying mobile, have them create a “mobility account,” using the
money that they would have used to own and operate their own vehicle. For example,
the 2012 edition of the Canadian Automobile Association (CAA) Driving Costs bro-
chure indicates that it costs $13,654 to own and operate a mid-sized car, based on
32,000 km driven per year. The purpose of the mobility account is to have funds set
aside to cover the costs of alternative transportation. Patients and their families
can access the form for calculating driving costs by visiting the CAA Website
(www.caa.ca).
4.6 Compliance
An important consideration with involuntary driving cessation is compliance. Research
indicates that as many as 28% of people with dementia continue to drive, despite failing
an on-road assessment. Family members play a pivotal role in monitoring and managing
compliance with a stop-driving directive. Families have tried numerous methods to
ensure that a family member stops driving. Numerous suggestions have been made
to assist family members in getting a patient to stop driving, including hiding the keys,
disabling the car, cancelling the insurance or selling the car. However, evidence of the
success of these interventions is largely anecdotal.
Alcohol
Alert
5.1 Overview
Alcohol is a depressant drug that has both sedative and disinhibitory effects. It also
impairs a driver’s judgment, reflex control and behaviour toward others. Impairment
from alcohol use is the single most common risk factor for motor-vehicle-related crashes
and injury.
People charged by police for impaired driving will have their driving privileges restricted
according to provincial legislation. The guidelines provided here are not meant to conflict
with such legislation.
In some people who are regular users of alcohol, withdrawal from alcohol may trigger
seizures. For seizures induced by alcohol withdrawal, see section 11.4.7.
5.2 Assessment
5.2.1 Clinical history
Researchers have identified a group of drivers (often referred to as “hard-core
drinking drivers”) who drive with blood alcohol levels averaging twice the
legal limit, have previous driving convictions and licence suspensions, may
drive without a valid driving licence and likely need treatment for an alcohol
use disorder.
A number of clinical “red flags” have been identified, which may indicate
ongoing alcohol use that will impair ability to drive safely. These indicators
include
• driver with at least 1 previous driving offence, especially an alcohol- or
drug-related offence
• driver arrested with blood alcohol concentration of 32.6 mmol/L (equivalent
to 0.15% or 150 mg/100 mL) or more (the low risk of detection implies that
they have probably driven in this condition previously)
Alcohol 20
• clinical diagnosis of alcohol dependence or abuse
• resistance to changing drinking-and-driving behaviour, often associated with
antisocial tendencies such as aggression and hostility
• concomitant use of illicit drugs (e.g., alcohol and marijuana or alcohol
and cocaine in combination; when ingested concomitantly, the latter
combination leads to the formation of cocaethylene, a dangerous, longer-
lasting toxic metabolite)
• male gender
• age 25–45 years
• education level: high school or less
• history of prior traffic or other criminal offences
• risk-taking behaviour in situations other than driving
• evidence of poor judgment in situations other than driving
• evidence of aggression in situations other than driving
• lifestyle associated with fatigue and lack of sleep
• intoxication at the time of a routine office visit.
People demonstrating drinking-and-driving behaviour, those showing evidence of
driving while impaired and those assessed as having a high probability of driving
while impaired should not drive any motor vehicle until further assessed.
Physicians are encouraged to use screening tools, such as the Alcohol
Screening, Brief Intervention and Referral tool (previously known as the Alcohol
Risk Assessment and Intervention tool; www.sbir-diba.ca) made available by
the College of Family Physicians of Canada (CFPC) for identifying problems
and helping their patients to reduce the risks of alcohol-related harm. More
comprehensive assessment and the facilitation of behavioural changes require
asking open-ended questions and engaging individuals in reflective dialogue
to enhance their awareness of ongoing problems. Willingness to participate in
self-reflection and to honestly face personal issues and dysfunctional emotional
responses and a commitment to change are critical to the sustained action
required to maintain recovery.
Physicians need to be familiar with the signs and symptoms that would raise
concerns about drinking and driving. Screening and assessment for appropriate
referrals need to be considered, in addition to reporting patients to the
provincial ministry of transport, in accordance with applicable provincial
legislation. Physicians should be aware that reporting drinking-and-driving
behaviour to licensing authorities in some jurisdictions might lead to immediate
suspension of the person’s licence pending further assessment.
Any level of alcohol use disorder warrants diagnostic evaluation and
treatment planning to reduce driving risk. Treatment may include referral to a
rehabilitation program, attendance at mutual-support groups (e.g., Alcoholics
Anonymous) or both. Continuing care and biological monitoring to ensure
remission must be considered to ensure fitness to drive.
Alcohol 22
The National Institute on Alcohol Abuse and Alcoholism has a fact sheet
comparing the changes in the diagnostic criteria for alcohol use disorder
in the Diagnostic and Statistical Manual of Mental Disorders, 5th edition
(DSM-5, published in 2013) with those in the previous edition, DSM-IV (2000)
(pubs.niaaa.nih.gov/publications/dsmfactsheet/dsmfact.pdf). Although the
Medical Council of Canada has adopted DSM-5 for examination purposes
(mcc.ca/2014/01/transition-to-dsm-5/), many physicians, especially addiction
medicine and occupational medicine specialists, remain critical of the loss of
clear differentiation between the definitions of abuse and of dependence.
This differentiation has been important in the workplace; dependence is
considered a workplace disability that requires a duty to accommodate,
whereas abuse does not require the same duty. As well, the presence of an
alcohol dependence has additional implications for treatment.
Alcohol-related problems must also be considered in the context of the latest
definition of addiction, as established by the American Society of Addiction
Medicine (ASAM) in 2011 and adopted by the Canadian Society of Addiction
Medicine (Appendix G). Addiction includes substance dependence, whereas
substance abuse is a term that is better avoided. Hazardous use (episodic) and
harmful use (regular) that are below threshold for a diagnosis of addiction are
the preferred terms, as defined by ASAM. The ASAM Standards of Care for the
Addiction Specialist Physician (adopted January 29, 2014; www.asam.org/docs/
default-source/publications/standards-of-care-final-design-document.pdf)
are also a useful resource, as is ASAM’s work on the ASAM Criteria: Treatment
Criteria for Addictive, Substance-Related, and Co-occurring Conditions, 3rd
edition, and CONTINUUM,TM The ASAM Criteria Decision Engine (www.asam.
org/quality-practice/guidelines-and-consensus-documents/the-asam-criteria).
Drugs
Alert
6.1 Overview
Patients taking illicit, non-prescription or prescription drugs known to have
pharmacologic effects or side effects that can impair the ability to drive should be
advised not to drive until their individual response is known or the side effects no longer
result in impairment (e.g., patients stabilized on chronic opioid therapy for chronic pain
or opioid dependence). Keep in mind that drugs can have unexpected adverse effects as
well, which may affect ability to drive.
There is growing concern that there is significant impairment among commercial drivers
due to alcohol, cannabis (marijuana or hashish) and its derivatives, and stimulants. Alcohol
and cannabis are well known to deteriorate driving performance. Although stimulants
are sometimes used for fatigue management by truck drivers on long hauls, studies have
shown that stimulant users were found to engage in more risky driving behaviours, to
show poorer compliance with traffic and driving regulation, and to be at greater risk
of falling asleep and of crashes. Studies of motor vehicle accidents and impairment
after taking medications have demonstrated increased risk with antidepressants,
benzodiazepines and Z-drugs, which are commonly prescribed as sleep aids. Although
Z-drugs, such as zopiclone, are marketed as non-benzodiazepines, they act on the
benzodiazepine receptor complex and are clearly sedative-hypnotics. The effects of
zopiclone 7.5 mg have been found to be equivalent to blood alcohol concentrations of
Drugs 24
0.5–0.8 mg/mL. Residual effects that led to lane weaving and speed variability while
driving have been found to persist at least 11 hours after the nighttime dose.
Concomitant use of several drugs (e.g., alcohol combined with antihistamines,
benzodiazepines or Z-drugs) may intensify side effects. In the elderly, increasing the
number of prescribed medications, regardless of type, may be associated with increased
risk of driving impairment due to cognitive side effects and drug interactions, especially
when 5 or more medications were dispensed.
Appropriate patient assessment is essential, including consideration of substance
dependence, to ensure that the risk of impairment while driving is not compounded.
Since the last edition of this guide, the Diagnostic and Statistical Manual of Mental
Disorders, 4th edition (DSM-IV; APA, 2000) has been replaced by the 5th edition (DSM-5;
APA, 2013). As discussed in section 5, Alcohol, although the Medical Council of Canada
has adopted DSM-5 for examination purposes (mcc.ca/2014/01/transition-to-dsm-5/),
many physicians, especially addiction medicine and occupational medicine specialists,
remain critical of the loss of clear differentiation between the definitions of abuse and
of dependence. This differentiation has been important in the workplace; dependence
is a workplace disability that requires a duty to accommodate, whereas abuse does
not require the same duty. As well, the presence of a drug dependence has additional
implications for treatment.
Patients with a diagnosis of substance use disorder with dependence need specialized
treatment. They must not drive until sufficient stability is achieved in recovery (see
section 6.4, Addiction).
Continuing effects of prescribed medications (e.g., chronic opioid therapy for chronic
pain or opioid dependence) do not result in impairment affecting driving. Keep in mind
that medications taken as directed or prescribed can have unexpected adverse effects
as well.
Care and biological monitoring to ensure remission must be considered to ensure fitness
to drive. It is important for primary care physicians to monitor patient compliance with
treatment recommendations and recovery, as the risk of relapse remains for the duration
of the person’s life. Clinical judgment is required in assessing the risk of using drugs and
driving. Consultation with an addiction medicine physician should be considered if the
primary care physician has any degree of uncertainty about the individual’s recovery.
Patients experiencing a reaction to withdrawal from psychoactive or psychotropic
medications may be temporarily impaired in their driving ability and should be advised
to refrain from driving until the acute symptoms have abated.
6.3.3 Opioids
Euphoria, depression or inability to concentrate can follow the use of opiates
Drugs 26
such as codeine (prescription or OTC), heroin, morphine and synthetic opioids
such as meperidine and fentanyl. Patients should be assessed for side effects,
as well as frequency of use, tolerance and dependence. Patients on long-term
prescribed opioid analgesic therapy should be monitored for side effects,
especially drowsiness.
Patients on a formal opioid agonist maintenance program of methadone
or buprenorphine prescribed by a physician are usually eligible for Class 5
and 6 drivers’ licences. A waiting period following initiation of an agonist
maintenance program is recommended before resumption of driving, and
clinical monitoring for concomitant use of other drugs is recommended (e.g.,
by urine drug screening). Patients in opioid agonist treatment programs may
also be eligible for certain commercial licences. Assessment and follow-up
monitoring need to be tailored to the individual.
6.3.5 Hallucinogens
Drugs such as cannabis (marijuana or hashish) and its derivatives, lysergic
acid diethylamide (LSD) and methylenedioxymethamphetamine (MDMA)
alter perception. Driving is contraindicated if any of these drugs is causing
impairment. Patients using medicinal marijuana must be assessed on an
individual basis to determine safety related to driving. It is illegal to drive a
motor vehicle while under the influence of any drug that causes impairment of
the driver’s ability to safely operate a motor vehicle, regardless of whether the
drug has been prescribed by a physician.
6.3.6 Inhalants
Inhalants, such as solvents, glue and gasoline, are toxic to the central nervous
system. Use of these inhalants may also result in substance dependence and
impairment of the ability to operate a motor vehicle during acute intoxication
or because of chronic damage to the brain.
6.3.8 Anticonvulsants
Some of the drugs used to control epileptic seizures can cause drowsiness
in certain patients, particularly when first prescribed or when the dose is
increased. Patients should be closely observed and warned not to drive while
this side effect persists. Patients taking these drugs may also be restricted
from driving because of the underlying seizure disorder. Patients should be
advised of the risk of seizure activity and the potential for driving restriction
that may occur with dose adjustments. Please see section 11, Nervous system
in this guide, specifically the Alert Box at the beginning of the section, and
subsection 11.4, Seizures.
6.3.11 Anticholinergics
Anticholinergics frequently cause sedation and delirium (acute onset of
cognitive deficits often associated with hallucinations and fluctuating levels of
consciousness), especially in older people. Patients (and their families) should
be warned that people who experience these side effects should not drive.
Examples of drugs with possible anticholinergic effects include
antidepressants, antipsychotics, antihistamines and antipruritics,
antiparkinsonian agents, antispasmodics, and anti-emetics.
Drugs 28
evident with the newer dopamine agonists (ropinirole and pramipexole).
Patients requiring these medications must be cautioned about this risk and
advised not to drive if they experience daytime drowsiness or any episodes
of falling asleep without warning or in unusual settings (e.g., during a
conversation or a meal). Medication adjustment or treatment of an associated
sleep disorder may allow safe return to driving after a period of observation.
6.4 Addiction
Drug-related problems must be considered in the context of the latest definition of
addiction, as established by the ASAM in 2011 and adopted by the Canadian Society of
Addiction Medicine (Appendix G). Addiction includes substance dependence, whereas
substance abuse is a term that is better avoided. Hazardous use (episodic) and harmful use
(regular) that are below threshold for a diagnosis of addiction are the preferred terms,
as defined by ASAM. The ASAM Standards of Care for the Addiction Specialist Physician
(adopted January 29, 2014; www.asam.org/docs/default-source/publications/standards-
of-care-final-design-document.pdf) are also a useful resource, as is ASAM’s work on the
ASAM Criteria: Treatment Criteria for Addictive, Substance-Related, and Co-occurring
Conditions, 3rd edition, and CONTINUUM,TM The ASAM Criteria Decision Engine (www.
asam.org/quality-practice/guidelines-and-consensus-documents/the-asam-criteria).
Drugs 30
Section 7:
Aging
Alert
7.1 Overview
Most of the health-related conditions listed in this guide that affect driving are more
prevalent in older age groups. Older drivers may be involved in crashes because of the
accumulation of medical illnesses and/or medications that affect function.
Unfortunately, the standard physical examination does not directly assess functional
skills such as the ability to drive. At best, it can be used to detect the presence of
medical conditions and to evaluate their severity and related complications, which may
allow the physician to make judgments regarding possible effects on functions, such as
fitness to drive.
Despite the above limitations of the standard physical examination, most Canadian
provinces and territories require that physicians report patients who have medical
conditions that may make it unsafe for them to drive (see section 3: Reporting – when
and why). Even where such reporting is not mandatory, physicians may still be found
liable if they fail to report a patient who is later determined to have caused harm to
others as a result of medical impairment affecting fitness to drive.
When involved in motor vehicle crashes, older drivers suffer higher rates of morbidity and
mortality than younger drivers. Accurate assessments of fitness to drive allow physicians
to help their patients avoid disabling injury or death. Such assessments also help patients
and their families avoid the grief and legal repercussions associated with contributing to
the injuries or deaths of other road users or bystanders. Thus, assessing fitness to drive
represents a form of preventive health care that benefits not only one’s patients but also
the public. The reality is that, although physicians cannot completely assess all aspects
of fitness to drive, they can make significant contributions to this assessment that will
prevent unnecessary trauma to their patients and to the general public. While physicians
therefore represent a major part of the solution, it is unrealistic to expect them to be
able to detect all issues affecting fitness to drive in all situations. It should also be noted
that physicians do not determine licence status. Rather, physicians provide accurate,
timely and relevant data to allow licensing authorities to make the most appropriate
licensure decisions.
Aging 32
For cases in which physicians and family members are concerned but the CANDRIVE
fitness to drive assessment mnemonic does not yield any identifiable medical domains
where physicians can focus their diagnostic skills and for cases in which the functional
effects are too subtle to determine whether they represent a significant risk to fitness
to drive, physicians should consider referral to specialized driving assessment programs,
many of which provide on-road evaluation (Appendix E).
* Reprinted, with permission, from Molnar FJ, Simpson CS. Approach to assessing fitness to drive in patients
with cardiac and cognitive issues. Can Fam Physician 2010;56(11):1123–1129 (http://www.cfp.ca/content/
cfp/56/11/1123.full.pdf).
Aging 34
Section 8:
Alert
8.1 Overview
Current demographic trends predict major increases in the number of older drivers
over the next 20 years. Given that the prevalence of dementia increases with age, this
indicates that the number of older drivers with dementia will increase significantly.
Cognitive problems often have a direct effect on ability to drive safely. Physicians
must therefore not neglect any indications of possible cognitive compromises of fitness
to drive.
The term “dementia” encompasses a group of diseases (i.e., different types of dementia)
that may have different effects on the functional skills required for safe driving. It is
known that patients with Alzheimer’s dementia show a predictable decline in cognition,
with the decline in driving abilities over time being steep but less predictable (Duchek
et al., 2003). However, to date, no longitudinal studies of declines in driving ability
have been conducted for other forms of dementia. Nonetheless, certain characteristics
of these dementias may have implications for fitness to drive. For example, vascular
dementia can present with abrupt periods of worsening associated with the
accumulation of vascular lesions. Parkinson’s dementia and Lewy Body dementia are
often associated with motor, executive and visuospatial dysfunction, any of which can
be hazardous on the road. Furthermore, some frontotemporal dementias are associated
with early executive dysfunction and behavioural changes (e.g., anger control issues)
that may render driving hazardous. Finally, all people with dementia are more prone to
delirium, with unpredictable and sudden cognitive decline. Ultimately, then, progression
to unsafe driving status is unpredictable for patients with dementia.
8.8 Counselling patients with dementia who can still drive safely
If a patient with dementia is found to be still safe to drive, the patient and the family
should be made aware that this is a temporary situation and that, in time, the patient
will need to cease driving. This conversation regarding eventual retirement from driving
should be held as early as possible. Patients and families should also be advised that if
there is any significant worsening of cognition (including symptoms of delirium such as
slow mentation, decreased attention and focus, fluctuation or hallucinations) the patient
should stop driving immediately and should see his or her physician. When assisting
a patient with dementia to plan for future driving cessation, physicians can consider
providing the patient and family with a copy of the Driving and Dementia Toolkit: For
Patients and Caregivers (www.rgpeo.com/en/health-care-practitioners/resources/driving.
aspx). The patient’s fitness to drive should be reassessed every 6 to 12 months, or more
frequently if the cognitive impairment progresses. For further information on driving
cessation, see section 4.
8.11 Countermeasures
There is little data to support the safety of restricted licensing, co-piloting, or other
countermeasures for persons with dementia (Iverson, 2010)*.
_____________________________________________________________________________
* Iverson DJ, Grosneth GS, Reger MA, et al: Practice parameter update: Evaluation and management of driving risk
in dementia: Report of the Quality Standards Subcomittee of the American Academy of Neurology. Neurology 2010;
74:1316-132
Sleep disorders
Alert
9.1 Overview
Somnolence (sleepiness), with its associated reduction in vigilance, is an important
contributor to driver error and motor vehicle crashes. Somnolence can be due to lifestyle
issues, a sleep disorder or both.
The 2nd edition of the International Classification of Sleep Disorders outlines 8 categories
of sleep disorders: insomnias, sleep-related breathing disorders, hypersomnias of central
origin, circadian rhythm sleep disorders, parasomnias, sleep-related movement disorders,
unclassified disorders and other sleep disorders.
The recommendations that follow relate primarily to obstructive sleep apnea (OSA)
and narcolepsy, the 2 sleep disorders for which there is a reasonably clear association
between the disorder and the risk of a motor vehicle crash.
9.2 Assessment
Patients reporting excessive somnolence should be questioned in detail about the
adequacy and regularity of their sleep–wake cycle, as attention to this may improve
symptoms and reduce driving risk.
The following are some risk factors for sleep-related crashes:
• holding multiple jobs
• working a night shift
• nighttime driving (between midnight and 6 am)
• less than 6 hours of nighttime sleep
• long-duration driving or driving after being awake for more than 15 hours
• past history of drowsy driving
• daytime sleepiness
• recent (within a year) at-fault motor vehicle crash.
Patients with various sleep disorders may also have 1 or more of these risk factors and, as
a result, have varying levels of sleepiness. This may partly explain observed differences in
Sleep disorders 42
9.3.1 Driving recommendations for patients with OSA
The following recommendations should be made only when OSA has been
diagnosed by physicians familiar with the interpretation of sleep studies and/or
portable monitoring.
• Regardless of apnea severity, all patients with OSA are subject to sleep
schedule irregularities and subsequent sleepiness. Because impairment
from OSA, sleep restriction and irregular sleep schedules may be interactive,
all patients should be advised about the dangers of driving when drowsy.
• Patients with mild OSA without daytime somnolence who report no
difficulty with driving are at low risk for motor vehicle crashes and should be
safe to drive any type of motor vehicle.
• Patients with OSA, documented by a sleep study, who are compliant with
CPAP (defined as at least 4 hours per day of use on 70% of days over at least
a 30-day period within the previous 90 days; Ayas et al., 2014) or who have
had successful upper airway surgery should be safe to drive any type of
motor vehicle.
• Patients with moderate to severe OSA, documented by a sleep study, who
are not compliant with treatment and are considered at increased risk for
motor vehicle crashes by the treating physician should not drive any type
of motor vehicle.
• Patients with a high apnea–hypopnea index, especially if associated with
right heart failure or excessive daytime somnolence, should be considered
at high risk for motor vehicle crashes.
• Patients with OSA who are believed to be compliant with treatment but
who are subsequently involved in a motor vehicle crash in which they were
at fault should not drive for at least 1 month. During this period, their
compliance with therapy must be reassessed. After the 1-month period,
they may or may not drive depending on the results of the reassessment.
9.4 Narcolepsy
Narcolepsy is characterized by recurrent lapses into sleep that are often sudden and
irresistible and that typically last 10–15 minutes. Narcolepsy may be accompanied by
cataplexy (sudden bilateral loss of muscle tone) during wakefulness, sleep paralysis
(generalized inability to move or to speak during the sleep–wake transition) and vivid
hallucinations at sleep onset.
Although there is a clear association between crash risk and narcolepsy, this association is
not as well studied as that between crash risk and OSA.
Up to 40% of people with narcolepsy may report sleep-related motor vehicle crashes.
Their risk for crashes is about 4 times that of control groups. Patients with cataplexy
and sleep paralysis are believed to be at greatest risk for crashes, based on the relative
unpredictability of these symptoms. In a study of narcoleptic patients with cataplexy, 42%
reported having experienced cataplexy while driving and 18% reported sleep paralysis
while driving. There is little information on the effect of treatment on risk for crashes.
Sleep disorders 44
Section 10:
Psychiatric disorders
Alert
10.1 Overview
The term “psychiatric disorders” encompasses numerous cognitive, emotional and
behavioural conditions. Determining fitness to drive in a patient with a psychiatric
disorder is often complex. There is a great deal of individual variation among patients
with psychiatric disorders, particularly in the critical area of insight, and multiple
conditions often coexist. Many psychiatric disorders are chronic and subject to relapse; as
a consequence, ongoing monitoring is required.
The adverse effects of treatment or medication may pose a hazard to driving ability (see
section 6, Drugs). However, individuals with psychiatric disorder(s) may well be safer
drivers with psychotropic drugs than without them.
Although driving-risk researchers have focused on the major clinical psychiatric disorders,
physicians need also to consider substance use disorders (see section 5, Alcohol, and
section 6, Drugs) and personality disorders, the effects of psychosocial stressors, and the
patient’s functional capacity when assessing fitness to drive in a patient with a psychiatric
disorder. Factors such as sleep deprivation, fatigue, stress or high trait anxiety may
aggravate existing problems.
Psychiatric disorders 46
Insight is critical to enable drivers to drive within their limitations and to know how
and when these limitations change. Poor insight in patients with psychiatric disorder(s)
may be evidenced by non-adherence to treatment, trivialization of the driver’s role in a
crash, or repeated involuntary admissions to hospital (often as a result of discontinuing
prescribed medication).
A driver’s ability to be aware of any cognitive limitations should be assessed, along with
his or her willingness to adapt his or her driving to these limitations.
Psychiatric disorders 48
Most treatment of depression is with newer-generation drugs rather than the
older tricyclic agents. Tricyclic antidepressants have been associated with an
increased risk of motor vehicle crashes, especially at higher doses or if multiple
agents are used. While, theoretically, selective serotonin reuptake inhibitors
and other newer-generation antidepressants have a pharmacological profile
associated with lower risk of cognitive impairment, the literature is less clear.
Some epidemiological studies have suggested an increased risk of collision also
associated with these newer medications, but interpretation of this research
is limited by indication and channelling bias. The general principles outlined in
this chapter and especially the alert box should be of foremost consideration.
Electroconvulsive therapy (ECT) may induce sustained confusion in 1 of every
200 patients. Those receiving outpatient ECT need to comply with standard
guidelines for not driving after anesthesia and should take extra time to
recover before returning to driving if they are experiencing any memory
problems after ECT.
Rapid-rate transcranial magnetic stimulation (rTMS) is reported to produce
no evidence of cognitive impairment when used for treatment of depression.
In fact, Turriziani et al. (2012) reported greater memory improvement among
patients with mild cognitive impairment relative to healthy controls after
administration of rTMS to the dorsolateral prefrontal cortex.
Aduen et al. (2015) contrasted the driving risks associated with adult attention
deficit/hyperactivity disorder (ADHD) and those associated with depression
relative to those of a typical peer control group. Depression, but not ADHD,
predicted increased risk for self-reported injury following collisions (OR = 2.4)
(see also section 10.4.6, Attention deficit/hyperactivity disorder).
Because of very frequent comorbidity, patients diagnosed with mood or
anxiety disorders should also be screened for ADHD.
Psychiatric disorders 50
Some of these adverse outcomes are also linked to and exacerbated by
comorbidity with oppositional defiant disorder, conduct disorder or antisocial
personality disorder.
Recently, a multi-site study using large general population samples (Aduen
et al., 2015) contrasted the driving risks associated with adult ADHD and with
depression relative to those of a peer control group. Diagnoses of ADHD and
depression were based on norm-referenced questionnaires, resulting in 275
adults identified with ADHD, 251 with depression, and a healthy control group
of 1,828 adults. Primary outcomes included self-reported traffic collisions,
moving violations, collision-related injuries and collision fault (in previous 3
years). Accounting for demographic differences, ADHD but not depression was
associated with about twice the risk for multiple violations (OR = 2.3), multiple
collisions (OR = 2.2), and collision fault (OR = 2.1). The authors concluded that
adult ADHD is uniquely linked to increased adverse driving outcomes that are
not evident in depression and are clearly greater than risks seen in general
population healthy adults. Identification of the specific mechanisms underlying
this risk will be critical to designing effective interventions to improve long-
term functioning for drivers with psychiatric disorder(s) associated with a
higher risk of collision.
Texting on cell phones while driving markedly worsens the driving performance
of teens both with ADHD and without the disorder (Narad et al., 2013; Kingery
et al., 2015; Llerena et al., 2015).
A case–control study (n = 205 + 200) conducted by Safiri et al. (2013) in Iran
found an association between adult ADHD and motorcycle traffic injuries.
ADHD scores in all 4 subscales of the DSM-IV diagnostic criteria were
significantly higher in the case (motorcycle injury) than in the control study
group (noting that many motorcycle crashes may result in death or brain injury
and the role of ADHD will remain unknown). The authors recommend a role for
psychological screening and, if required, consultation with respect to ADHD
during the motorcycle licensing process.
Chang et al. (2014) studied the association between ADHD and the risk of
serious motor vehicle collision (MVC) (identified as an emergency hospital visit
or death due to MVC) and explored whether ADHD medication influences this
risk among patients with ADHD. Through the Karolinska Institute, a total of
17,408 patients with a diagnosis of ADHD were observed from January 1, 2006,
through December 31, 2009, for serious motor vehicle collisions documented in
Swedish national registers. To study the effect of ADHD medication, the authors
compared the risk of MVC during a period when medication was used with the
risk during a period without medication among the same patients. Compared
with individuals without ADHD, male and female patients with ADHD had an
increased risk of MVC. In male patients with ADHD, medication was associated
with a 58% risk reduction (hazard ratio, 0.42; 95% CI, 0.23 to 0.75), but there
Psychiatric disorders 52
Redelmeier et al. (2010) conducted a population-based case–control study in
Ontario to examine the amount of road trauma involving teenage male youth
that might be explained by prior “disruptive behaviour disorders” (specifically,
ADHD, conduct disorder and oppositional defiant disorder). A history of
disruptive behaviour disorders was significantly more frequent among trauma
patients than controls, equal to a one-third increase in the relative risk of road
trauma. The risk explained about 1 in 20 crashes, was apparent years before
the event, extended to those who died, and persisted among those injured
as pedestrians.
With the present state of knowledge, it seems reasonable to refer aggressive
drivers with insight for specialized CBT groups, where available. Those
without insight will likely only be dealt with by court-ordered treatment and
administrative prohibitions from driving, although motivational interviewing
strategies may be of some benefit.
Nervous system
Alert
11.1 Overview
Safe driving requires concentration, a reasonable level of intelligence and maturity,
complete control over all muscle movements and freedom from the distracting influence
of severe pain. In addition, a safe driver must always be alert, fully conscious and capable
of quickly appreciating and responding to changing traffic and road conditions.
A driver with a history of any type of seizures, due to epilepsy or any other cause, is
generally fit to drive a private vehicle if there have been no seizures during the previous
6 months. For certain types of seizures that do not affect the level of consciousness and
with symptoms that do not affect driving, the seizure-free period may be waived if the
seizure pattern has remained constant for at least 12 months.
This section lists and discusses the most common neurologic conditions that can
adversely affect driving ability.
11.3 Syncope
A single occurrence of syncope that is fully explained and, given the etiology, is unlikely
to recur may require no more than close observation. However, patients with a history of
Nervous system 54
several fainting spells or repeated unexplained falls should not drive until the cause has
been determined and successful corrective measures taken. See section 14.4, Syncope.
11.4 Seizures
As for all conditions, in all instances where a temporal recommendation is made, the time
period should be considered a general guideline. Individual circumstances may warrant
prolonging or reducing the time period suggested.
The recommendations for seizures are presented in both tabular (Table 2) and
text format.
Seizures only • Drive after 1 year from initial • No driving commercial vehicles
in sleep or seizure if drug levels are for at least 5 years
immediately on therapeutic
wakening
Medication withdrawal or change:
Initial • No driving for 3 months from • No driving for 6 months from
withdrawal or the time medication is discon- the time medication is discon-
change tinued or changed tinued or changed
If seizures • Resume driving if seizure free • Resume driving if seizure free
recur after for 3 months for 6 months (Recommenda-
withdrawal or tions for individual patients
change may differ on an exceptional
basis.)
Long-term • Drive any vehicle if seizure free off medication for 5 years with no
withdrawal and epileptiform activity within previous 6 months on waking and sleep
discontinuation EEG
of medication
Auras (simple Drive if: Drive if:
partial seizures)
• Seizures are unchanged for at • Seizures remain benign for at
least 12 months least 3 years
• No generalized seizures • No generalized seizures
• Neurologist approves • Neurologist approves
• No impairment in level of • No impairment in level of
consciousness or cognition consciousness or cognition
• No head or eye deviation with • No head or eye deviation with
seizures seizures cont'd
Nervous system 56
cont'd from previous page
Nervous system 58
11.4.5 Withdrawal of seizure medication or medication change
The following recommendations do not apply to voluntary cessation of
antiseizure medication by the patient or instances of missed doses of
prescribed medication.
Initial withdrawal or change: Some patients with fully controlled seizures
whose antiseizure medication is withdrawn or changed have a recurrence of
their seizures. Because the relapse rate with drug withdrawal is at least 30%–
40%, patients must not drive for 3 months from the time their medication is
discontinued or changed. Such patients should always be cautioned that they
could have further seizures and should be counselled as to the risk factors for
seizure recurrence.
The same concerns and conditions apply to commercial drivers as to private
drivers. However, the period of observation before resuming driving is 6
months, and a normal EEG, preferably both awake and asleep, should be
obtained during this time. If the evaluation is being done in the context of
medication withdrawal, the EEG should be done when serum drug levels are
non-measurable.
If seizures recur: If seizures recur after a physician has ordered
discontinuation of or a change in antiseizure medication, patients can resume
driving, provided they take the previously effective medication according to
the physician’s instructions. Private drivers must be seizure free for 3 months
and commercial drivers for 6 months before resuming driving.
Long-term withdrawal or discontinuation: Patients with epilepsy whose
anticonvulsant medication has been discontinued may drive any class of
vehicle once they have been seizure free off medication for 5 years, with no
epileptiform activity being recorded during a waking and sleep EEG obtained in
the 6 months before resumption of driving.
Nervous system 60
11.6 Severe pain
Severe pain from such causes as migraine headache, trigeminal neuralgia or lesions of
the cervical or lumbar spine can decrease concentration or limit freedom of movement
to a degree that makes driving extremely hazardous. This is a particular concern for
commercial drivers, whose responsibilities or working conditions may prevent them from
stopping work even if the pain becomes disabling.
In addition, prescription and over-the-counter painkillers may interfere with a person’s
ability to drive safely. However, some patients may be rendered capable of driving
despite their pain by the use of these medications. Patients who experience frequent,
chronic and incapacitating pain should be advised to avoid driving while incapacitated.
The underlying condition causing the pain may affect the person’s fitness to drive, and a
functional evaluation may be indicated.
Nervous system 62
Section 12:
Vision
Alert
*Some jurisdictions (e.g., Quebec) have different requirements for private drivers (i.e., field less than 100° along the
horizontal meridian and 10° continuous above and 20° below fixation, with at least 30° on each side of the vertical
meridian, with both eyes open and examined together).
12.1 Overview
The following recommendations are based in large part on the work of the Canadian
Ophthalmological Society’s expert working group on driving and vision standards.
When a patient is visually impaired, the physician should inform the patient of the
nature and extent of the visual defect and, if required, report the problem to the
appropriate authorities.
When minor visual defects are not accompanied by cognitive defects or neglect, most
drivers are capable of compensating for the defects. For example, most people adapt
to the loss of an eye within a period of several months. Recent studies indicate that
experienced drivers can compensate for a loss of visual acuity if they are in familiar
surroundings and they limit their speed. In these circumstances, functional assessments
are indicated.
This section presents information about the recommended visual acuity and visual field
needed for safe driving (section 12.2, Recommended visual functions). Actual standards
for these functions are set by provincial or territorial licensing authorities and may vary
among jurisdictions, as well as differing from the recommendations in this section,
*Some jurisdictions require an acuity higher than 20/400 (6/120) in the worse eye. For example, some jurisdictions
have a standard of 20/100 (6/30) or better in the worse eye for commercial licences. Other jurisdictions, such as
Quebec, no longer have requirements for the worse eye.
Vision 64
12.2.3 Diplopia
Diplopia (double vision) within the central 40° (i.e., 20° to the left, right, above
and below fixation) of primary gaze is incompatible with safe driving for all
classes of licence. Individuals who have uncorrected diplopia within the central
40° of primary gaze should be referred to an ophthalmologist or optometrist
for further assessment. If the diplopia can be completely corrected with
a patch or prisms to meet the appropriate standards for visual acuity and
visual field, the individual may be eligible to drive. Before resuming driving
with a patch, there should be an adjustment period of 3 months or a period
sufficient to satisfy the treating ophthalmologist or optometrist that adequate
adjustment has occurred.
Vision 66
or contact lenses) that they will use for driving. The examiner should assess visual acuity
under binocular (both eyes open) or monocular conditions, as required by the relevant
standard. It is recommended that visual acuity be assessed using a Snellen chart or
equivalent at the distance appropriate for the chart under bright photopic lighting
conditions of 275–375 lux (or greater than 80 candelas/m2). Charts that are designed to
be used at 3 m (9.8 ft) or greater are recommended.
Visual field: When a confrontational field assessment is carried out to screen for visual
field defects, the following procedure is recommended, at a minimum:
1. The examiner is standing or seated approximately 0.6 m (2 ft) in front of the
examinee, with eyes at about the same level.
2. The examiner asks the examinee to fixate on the nose of the examiner with both
eyes open.
3. The examiner extends his or her arms forward, positioning the hands halfway be-
tween the examinee and the examiner. With arms fully extended, the examiner asks
the examinee to confirm when a moving finger is detected.
4. The examiner should confirm that the ability to detect the moving finger is continu-
ously present throughout the area specified in the applicable visual field standard.
Testing is recommended in an area of at least 180° horizontal and 40° vertical,
centred around fixation.
If a defect is detected, the individual should be referred to an ophthalmologist or
optometrist for a full assessment.
When a full assessment is required, the binocular visual field should be assessed using
a III/4e Goldmann-type target or the closest equivalent. The Esterman functional vision
test on the Humphrey visual field analyzer or kinetic perimetry with static exploration for
scotomata on the Goldmann perimeter is recommended. When binocular assessments
are not possible, monocular assessments will be considered.
Some automated testing devices used in driver testing centres have a procedure for
assessing visual field. However, these tests are often insensitive to many types of visual
field defect, and none tests greater than 140° in the horizontal median. Thus, they may
not be adequate for screening purposes.
Diplopia: Anyone reporting double vision should be referred to an ophthalmologist or
optometrist for further assessment.
Contrast sensitivity: Assessment of contrast sensitivity is recommended for those who
are referred to an ophthalmologist or optometrist for vision problems related to driving.
Contrast sensitivity may be a more valuable indicator of visual performance in driving
than Snellen chart visual acuity. Increased use of this test is encouraged as a supplement
to visual acuity assessment.
Contrast sensitivity can be measured with a number of commercially available tools.
Examples* include the Pelli-Robson letter contrast sensitivity chart, either the 25% or the
11% Regan low-contrast acuity chart, the Bailey-Lovie low-contrast acuity chart and the
_____________________________________________________________________________
* This list may not be exhaustive and does not constitute an endorsement.
Vision 68
There are many other conditions that may cause vision problems. If a vision problem is
suspected as a result of a medical condition, it is recommended that the individual be
referred to an ophthalmologist or optometrist for further assessment of visual function.
Night driving: When assessing a driver’s ability to drive at night, the following factors
should be considered: mesopic visual acuity, glare sensitivity, contrast sensitivity and the
presence of pathology such as cataracts, retinitis pigmentosa, corneal scarring and
retinal diseases.
Vision aids and driving: Telescopic spectacles (bioptic devices), hemianopia aids and other
low-vision aids may enhance visual function. The problems associated with their use while
driving can include loss of visual field, magnification causing apparent motion and the
illusion of nearness. Although expert opinion does not support their use by low-vision
drivers, recent Canadian legal decisions oblige licensing authorities to evaluate their use
on an individual basis for drivers whose vision does not meet the established standards.
These aids cannot be used to enable the user to meet the visual standards for testing
by the licensing authority. Consequently, a driver must demonstrate that the use of the
low-vision aid permits him to drive safely despite failure to meet the established visual
standard. An on-road test is the usual means of functional assessment in these cases. It
should be noted that drivers using telescopic lenses look through the lenses only 5%–
10% of the time that they are driving. Consequently, some jurisdictions assess the driver
without the lenses to evaluate fitness to drive under the conditions that will prevail for
90% of the time behind the wheel.
Alert
13.1 Overview
There are few data to indicate that hearing impairment affects driving ability. In certain
circumstances, meeting certain standards of hearing is recommended. Vestibular
dysfunction causing vertigo may affect ability to drive.
To date there is no conclusive evidence linking drivers’ hearing loss with an increased
risk of motor vehicle crashes. However, people with severe hearing loss will have limited
ability to detect emergency sirens and other roadside sounds (e.g., train horns and
crossings) and, where applicable, should be encouraged to wear hearing assistive devices
while driving.
13.2 Hearing
13.2.1 Standards
There are no hearing standards for private drivers in Canada.
The following standards, as applied to the person’s better ear, are
recommended for commercial drivers.
If a hearing-impaired person drives a Class 2 or 4 vehicle, he or she should first
undergo audiography performed by an audiologist or otolaryngologist. Drivers
with Class 2 or 4 licences should have a corrected hearing loss of no more than
40 dB averaged at 500, 1000 and 2000 Hz and a corrected word recognition
score of at least 50%–60%.
Drivers of Class 1 and 3 vehicles who wish to drive in the United States must
meet the same standards as outlined above for drivers of Class 2 and 4
vehicles. Although no hearing standards apply for holders of Class 1, 3, 5 or 6
licences in Canada, drivers transporting dangerous goods, regardless of the
class of vehicle, should meet the standards for Class 2 and 4 licences as noted
in the previous paragraph.
Cardiovascular diseases
Alert
Unstable cardiac patients who require admission to hospital or intensified follow-up should
cease driving immediately until they can be shown to be at an acceptably
low risk.
14.1 Overview
These recommendations are based on the report of the Canadian Cardiovascular Society’s
2003 Consensus Conference, Assessment of the Cardiac Patient for Fitness to Drive and
Fly. They are intended to assist decision-makers in assessing the fitness of cardiac patients
to drive and are not intended to diminish the role of the physician’s clinical judgment in
individual cases.
Recommendations are presented in tabular form. For definition of terms, see section 14.10.
Details regarding these and other recommendations can be found in the full report.*
Please note:
• There are no prospective, controlled studies in which patients have been randomly
chosen to be permitted or proscribed the driving privilege, nor are there any studies in
which patients have been randomly chosen to receive or not to receive physician advice
not to drive.
• The defined standard of risk (see the “risk of harm” formula, Appendix F), while sensibly
derived, is arbitrary and is not based on any evidence other than what has been accept-
able historically.
• Given that all recommendations for driving eligibility are based on comparison with this
arbitrary standard, they are based on expert
opinion only.
• Application of the “risk of harm” formula throughout this section creates internal
consistency among recommendations based on cardiovascular disorders, but does not
imply consistency with recommendations based on other conditions or disorders,
either in this guide or elsewhere.
• Wherever possible, best evidence was used to calculate the risks of driving, but the
evidence itself does not support or deny licence restrictions for cardiac patients nor the
mandatory reporting of such patients by their physicians.
_____________________________________________________________________________
*Assessment of the cardiac patient for fitness to drive and fly: final report. Ottawa : Société canadienne de cardiologie;
2003. Available: https://www.ccs.ca/images/Guidelines/Guidelines_POS_Library/DF_CC_2003_ES.pdf (accessed May
4th, 2017).
Cardiovascular diseases 72
14.2 Coronary artery disease
Most patients with coronary artery disease (CAD) pose a low risk to other road users
while driving. However, certain conditions require careful evaluation and judgment. It
seems fair to conclude on both clinical and physiologic grounds that the cardiovascular
workload imposed by driving a vehicle is very light, and the risk that driving will provoke
a recurrent acute coronary syndrome incident causing incapacitation is extremely small.
Although a small percentage of acute coronary syndromes will present with sudden
cardiac incapacitation, it is not possible with contemporary risk stratification to select
these patients in a meaningful way.
*Minor LV damage is classified as an MI defined only by elevated troponin with or without ECG changes
and in the absence of a new wall motion abnormality. Significant LV damage is defined as any MI that is
not classified as minor.
Notwithstanding any of the above recommendations, angiographic demonstration of 50% or greater reduction in
the diameter of the left main coronary artery should disqualify the patient from commercial driving, and 70% or
greater should disqualify the patient from private driving, unless treated with revascularization.
*Examples include, but are not limited to, VF within 24 hours of myocardial infarction, VF during coronary
angiography, VF with electrocution, VF secondary to drug toxicity. Reversible cause VF recommendations overrule the
VF recommendations if the reversible cause is treated successfully and the VF does not recur.
Note: ICD = implantable cardioverter defibrillator; LVEF = left ventricular ejection fraction; VF = ventricular
fibrillation; VT = ventricular tachycardia.
Cardiovascular diseases 74
14.3.2 Paroxysmal supraventricular tachycardia,
atrial fibrillation or atrial flutter
Private driving Commercial driving
With impaired level of Satisfactory control Satisfactory control
consciousness
cont'd
Note: AV = atrioventricular; LBBB = left bundle branch block; RBBB = right bundle branch block.
Cardiovascular diseases 76
14.3.7 Implantable cardioverter defibrillators
Private driving Commercial driving
Primary prophylaxis; NYHA 4 weeks after implant Disqualified*
Classes I–III
*ICDs may sometimes be implanted in low-risk patients. Individual cases may be made for allowing a commercial
driver to continue driving with an ICD provided the annual risk of sudden incapacitation is felt to be 1% or less.
†The 6-month period begins not at the time of ICD implant, but rather at the time of the last documented episode of
sustained symptomatic VT, or syncope judged to be likely due to VT or cardiac arrest.
Note: ATP = antitachycardia pacing; ICD = implantable cardioverter defibrillator; NYHA = New York Heart
Association; VF = ventricular fibrillation; VT = ventricular tachycardia.
For patients who have a bradycardia indication for pacing as well, the additional criteria
under section 14.3.6 also apply.
All patients must be followed from a technical standpoint in a device clinic with
appropriate expertise.
*Inherited heart diseases may sometimes be identified to pose a very low risk to patients. Individual cases may be
made for allowing a commercial driver to continue driving despite the diagnosis of one of these diseases, provided
the annual risk of sudden incapacitation is felt to be 1% or less.
14.4 Syncope
Most episodes of syncope represent vasovagal syncope, which can usually be diagnosed
by history and do not warrant further investigation. When syncope is unexplained,
further testing is necessary to arrive at a diagnosis and direct possible therapy. Because
there is a small risk of recurrence and incapacitation during driving, consideration of
restriction of privileges is intuitive, to protect both the patient and the public.
A patient with structural heart disease (reduced ejection fraction, previous myocardial
infarction, significant congenital heart disease) is potentially at high risk and should
undergo driving restriction pending clarification of underlying heart disease and etiology
of syncope. It is well known that syncope, a previous aborted cardiac arrest, one or more
episodes of sustained ventricular tachycardia (VT) and a history of sudden death in young
family members are strong indicators of a high risk of sudden death.
Cardiovascular diseases 78
cont'd from previous page
Recurrent episode of
unexplained syncope (within Wait 3 months Wait 12 months
12 months)
Syncope due to documented
tachyarrhythmia, or
Refer to section 14.3.1
inducible tachyarrhythmia
at EPS
*No restriction is recommended unless the syncope occurs in the sitting position, or if it is determined that there may
be an insufficient prodrome to pilot the vehicle to the roadside to a stop before losing consciousness. If vasovagal
syncope is atypical, the restrictions for “unexplained” syncope apply.
Note: AVA = aortic valve area; EF = ejection fraction; NYHA = New York Heart Association.
Cardiovascular diseases 80
Private driving Commercial driving
NYHA Class I No restriction EF ≥ 35%
NYHA Class II No restriction EF ≥ 35%
NYHA Class IV
Receiving intermittent
outpatient or home Disqualified
inotropes
Heart transplant • 6 weeks after discharge • 6 months after discharge
• NYHA Class I or II • Annual assessment
• On stable • EF ≥ 35%
immunotherapy • NYHA Class I
• Annual assessment • Annual non-invasive test
of ischemic burden
showing no evidence of
active ischemia
14.10 Definitions
NYHA functional classification:
• Class I: Patients with cardiac disease but without resulting limitation of physical
activity. Ordinary physical activity does not cause undue fatigue, palpitation, dyspnea
or anginal pain.
• Class II: Patients with cardiac disease resulting in slight limitation of physical activity.
They are comfortable at rest. Ordinary physical activity results in fatigue, palpitation,
dyspnea or anginal pain.
• Class III: Patients with cardiac disease resulting in marked limitation of physical
activity. They are comfortable at rest. Less than ordinary activity causes fatigue,
palpitation, dyspnea or anginal pain.
• Class IV: Patients with cardiac disease resulting in inability to carry on any physical
Cardiovascular diseases 82
activity without discomfort. Symptoms of heart failure or anginal syndrome may be
present even at rest. If any physical activity is undertaken, discomfort increases.
Waiting period: The time interval following onset of a disqualifying cardiac condition,
initiation of a stable program of medical therapy or performance of a therapeutic
procedure (whichever is applicable) during which driving should generally be disallowed
for medical reasons.
• Recurrence of the disqualifying condition or circumstance during this time resets the
waiting period.
• If more than one waiting period would apply, the longer one should be used, except
where stated otherwise.
Satisfactory control (for supraventricular tachycardia, atrial fibrillation or atrial flutter,
which are associated with cerebral ischemia):
• Supraventricular tachycardia — Successful radiofrequency ablation of the substrate,
plus an appropriate waiting period (see section 14.3.2), or a 3-month waiting period
on medical therapy with no recurrence of SVT associated with cerebral ischemia
during this time.
• Atrial fibrillation or atrial flutter — A 3-month waiting period after appropriate
treatment during which there are no recurrences of symptoms associated with
cerebral ischemia. If atrial fibrillation is treated with AV node ablation and pacemaker
implantation, or if atrial flutter is treated successfully with an isthmus ablation (with
proven establishment of bidirectional isthmus block), then the waiting periods in
section 14.3.2 apply.
• Sustained ventricular tachycardia with a left ventricular ejection fraction greater than
or equal to 40% and no associated cerebral ischemia — Successful ablation of the
substrate plus a 1-week waiting period, or pharmacologic treatment plus the waiting
period specified in section 14.3.1.
Sustained ventricular tachycardia: Ventricular tachycardia having a cycle length
of 500 ms or less and lasting 30 seconds or more or causing
hemodynamic collapse.
Nonsustained ventricular tachycardia: Ventricular tachycardia ≥ 3 beats, having a cycle
length of 500 ms or less and lasting less than 30 seconds, without hemodynamic collapse.
14.11.2 Hypotension
Hypotension is not a contraindication to the operation of any type of motor
vehicle unless it has caused episodes of syncope. If syncope has occurred, the
patient should discontinue driving. If it is possible to prevent further attacks
by treatment, it is then safe to resume driving a private vehicle, but not heavy
transport or commercial vehicles.
14.12 Anticoagulants
Although the use of anticoagulant drugs is not by itself a contraindication
to driving any class of motor vehicle, the underlying condition that led to
prescribing the anticoagulant may be incompatible with safe driving.
Cardiovascular diseases 84
Section 15:
Alert
Patients who have experienced either a single or recurrent transient ischemic attack or
are experiencing residual symptoms from a probable stroke should not drive a motor
vehicle until a medical assessment is completed.
15.1 Overview
Cerebrovascular disease can cause physical, visuospatial or cognitive symptoms that can
lead to unsafe driving. A detailed history and thorough physical examination, including
an assessment of cognition, insight and judgment, are important. If a problem that
may affect driving is suspected, a comprehensive driver evaluation is the most practical
method of determining fitness to drive.
Where resources are available, assessment by a trained occupational therapist would be
optimal. An on-road test administered by the motor vehicle licensing authority can also
be helpful in assessing functional capacity to drive; however, such testing cannot always
be relied upon to reveal the true extent of the disability, given the examiner’s inability to
evaluate all potentially related physical (e.g., hemiparesis), visuospatial (e.g., visual field
deficits) and cognitive (e.g., dementia) issues.
15.3.2 Stroke
Patients who have had a stroke should not drive for at least 1 month. During
this time, they require assessment by their regular physician. They may resume
driving if
• the physician notes no clinically significant motor, cognitive, perceptual or
vision deficits during the general and neurologic examinations
• any underlying cause has been addressed with appropriate treatment
• a seizure has not occurred in the interim.
Any available information from the patient’s treating nurse, occupational
therapist, psychologist, physiotherapist, speech pathologist or social worker
should be reviewed to assist with the determination of deficits that may not be
visible or detected during an office visit.
Where there is a residual loss of motor power, a driving evaluation at a
designated driver assessment centre may be required (Appendix E). The driver
assessment centre can make recommendations for driving equipment or
vehicle modification strategies, such as use of a steering wheel “spinner knob”
or left-foot accelerator. Training in the safe use of the equipment should
be provided.
The physician should take particular care to note any changes in personality,
alertness, insight (executive functions), and decision-making ability, however
subtle and inconsistent, in patients who have had a stroke as these types of
changes could significantly affect driving ability. The physician may be assisted
by reports from reliable family members in discerning whether the patient’s
judgment and awareness are altered in day-to-day activities.
Patients with a right-brain stroke are usually verbally intact but very much
impaired with regard to their insight, judgment and perceptual skills. Such
15.4 Counselling
Support and counselling should be offered to patients who are unsafe to drive or who
resist giving up driving or being tested. Patients may find it difficult to deal with the loss
of their perceived independence. In addition, obtaining alternative transportation may
be challenging and time-consuming. The physician should point out to patients that they
may place themselves and others at risk for injury by driving. Referral to social services
will help patients to identify and apply for community resources. Stroke survivors with
physical disabilities may require door-to-door van service, for which medical justification
may be needed, and the physician should expect requests for documentation when
patients apply for such assistance.
15.5 Summary
Driving after stroke is possible, but patients must recognize that it is a privilege, not a
right. Evaluation of the patient must take into account any possible residual physical,
cognitive or perceptual impairment that might affect safe driving.
In general, if there is uncertainty about the patient’s ability to drive, a formal driving
evaluation, including an on-road assessment, should be performed.
Better screening tools and training methods to allow a return to driving after a stroke
are being developed, but they do not supplant the need for a comprehensive
medical evaluation.
87 CMA Driver’s Guide — 9th Edition
Section 16:
Alert
16.1 Overview
In cases of traumatic brain injury (TBI), the apparent severity of the original event may
not correlate with the degree of persisting cognitive dysfunction. There is also often
great variability in recovery: people with severe injury may have minor persisting deficits,
whereas those with apparently mild brain injury may have significant persisting deficits.
Although the term “mild traumatic brain injury” is clearly defined and widely used in the
medical literature, recent knowledge suggests that there is nothing mild about TBI, in
terms of its prevalence, the lack of adequate clinical attention it receives and, sometimes,
its enduring effects on functional capacity. Multiple cognitive and physical impairments,
including changes in reaction time and visual-motor processing, commonly occur after TBI
and can impair the ability to drive. The same is true for acquired brain injuries resulting
from anoxia, encephalitis, the effects of tumours or other cerebral insults. Common
causes of concussion may target frontal lobe areas that are involved in insight, decision-
making and impulse control.
Even with the increasing number of published articles on mild TBI and concussion,
there is very little evidence-based material on which to base recommendations.
A comprehensive effort to improve this situation includes 71 specific recommendations
for the assessment and treatment of patients with persisting symptoms after a brain
injury (Marshall et al., 2012).
Internationally, efforts are under way to develop a better understanding of and care for
patients “with our most complex disease in our most complex organ” while recognizing
the limitations of randomized controlled trials’ contribution to the research methodology
used (Tenovuo et al., 2012).
16.5 Counselling
Support and counselling should be offered to patients who are unsafe to drive or who
resist giving up driving or being tested. Finding alternative transportation may be
challenging and time consuming. TBI is often complicated by comorbid depression, and
the loss of driving privileges may contribute to the risk of depression. The physician
should advise patients that they may place themselves, family and others at risk for injury
by driving.
16.6 Summary
Driving after brain injury may be possible. Evaluation of the patient must take into account
any residual physical, cognitive or perceptual impairment to safe driving. Reporting
requirements will vary according to the jurisdiction where the physician practises.
In general, if there is uncertainty about a patient’s ability to drive, a formal driving
evaluation, including an on-road assessment by a professional experienced in driving
rehabilitation, should be performed.
It is anticipated that baseline cognitive screening and periodic re-testing will become more
widespread. Having such objective information will assist physicians in dealing with these
complex situations while more research is being done to inform guidelines for clinical care
and rehabilitation.
Better screening tools and training methods to allow a return to driving after TBI or ABI
are being developed, but they do not supplant the need for a comprehensive medical
evaluation.
Vascular diseases
Alert
17.1 Overview
The presence of an aortic aneurysm or deep venous thrombosis is the main concern with
respect to fitness to drive.
Vascular diseases 94
Following successful endovascular or open AAA repair, the patient may drive once he or
she has recovered, assuming that no other medical contraindication exists.
Thoracic and thoracoabdominal aneurysm rupture is also related to aneurysm size.
Prospective data comparing early surgery with conservative follow-up are not available.
The threshold for repair of thoracic and thoracoabdominal aneurysms is influenced by
size, extent and location of these aneurysms. Therefore, definitive recommendations
await prospective data.
Respiratory diseases
Alert
18.1 Overview
Some respiratory diseases may, if severe enough, interfere with the safe operation of a
motor vehicle. A decrease in the provision of oxygen to the brain could impair judgment,
reduce concentration and slow response times. Marked dyspnea may also limit physical
ability to operate a motor vehicle. It is important to note that suboptimal oxygenation
could destabilize respiratory illness, and the resulting insufficient cerebral oxygenation
could compromise driver fitness. Advanced respiratory disease, as well as morbid
obesity, may lead to decreased ventilation, and the resulting hypercapnia could lead to
psychomotor symptoms that may affect fitness to drive.
18.2 Assessment
Impairment associated with dyspnea can be characterized as
• Mild — Dyspnea when walking quickly on level ground or when walking uphill; ability
to keep pace with people of same age and body build walking on level ground, but not
on hills or stairs.
• Moderate — Shortness of breath when walking for a few minutes or after 100 m
walking on level ground.
• Severe — Too breathless to leave the house, breathless when dressing; presence of
untreated respiratory failure.
Respiratory diseases 96
physician has any doubt. Oxygen equipment must be safely secured in the vehicle. Please
refer to Table 4 for recommendations for patients with chronic respiratory d
isease.
Alert
• In severe cases, many endocrine and metabolic diseases, treated or untreated, may
impair judgment, motor skills or level of consciousness. In addition, metabolic or elec-
trolyte abnormalities may occur. If these factors are present or are likely to occur, then
the patient should be advised not to drive until the medical condition is stabilized.
• In an individual with diabetes who is using insulin or insulin secretagogues, the occur-
rence of symptoms of hypoglycemia severe enough to cause lack of judgment or loss of
consciousness, or to require the intervention of a third party, is an immediate contrain-
dication to driving.
19.1 Overview
Disturbances in the functioning of the endocrine glands may be the source of many
symptoms with a wide range of severity. Patients with suspected or confirmed endocrine
disorders should always be carefully evaluated to make certain that their symptoms do
not make them unsafe drivers. The endocrine and metabolic conditions discussed below
are among the most common ones that physicians may be called on to assess because of
their potential for interfering with driving safety. Fitness to drive must be assessed on a
case-by-case basis, as the range of signs and symptoms is highly variable.
19.7.3 Acromegaly
Patients with acromegaly who have started to develop muscle weakness,
pain, easy fatiguing, significant neurologic symptoms, visual disturbances,
cardiac enlargement, sleep disorders or intractable headaches should
discontinue all driving. After treatment, and if vision is satisfactory and other
symptoms do not significantly affect function, they should be able to resume
all driving safely.
19.8.3 Pheochromocytoma
Hyperfunction of the adrenal medulla due to the development of a
pheochromocytoma with headache, dizziness, tachycardia or blurred vision is
a contraindication to the operation of any type of motor vehicle, unless these
symptoms are significantly relieved by treatment.
Renal diseases
Alert
• A substantial proportion of dialysis patients may be unfit to drive or may have episodes
when they are temporarily unfit to drive (especially after dialysis treatments).
• Screening questionnaires are available that may help to identify patients who are at
risk for being unfit to drive and who might benefit from more detailed evaluation.
However, evidence is insufficient to mandate the routine use of these questionnaires
in clinical practice.
• Dialysis patients who are concerned about their ability to drive should be encouraged to
speak to a physician and avoid driving until their concern has been addressed.
• Medical and paramedical personnel should consider seat-belt pressure points when
implanting invasive medical devices (e.g., central venous catheters or peritoneal
dialysis catheters).
20.1 Overview
This section reviews issues associated with dialysis and renal transplantation. Patients
with end-stage renal disease may be treated with facility-based or home hemodialysis or
with home peritoneal dialysis. Most patients can continue to drive safely after adjusting
to a stable dialysis regimen.
Patients on dialysis often develop concurrent medical problems or general debility that
can lead to a temporary or permanent inability to drive safely. The attending physician
should counsel the patient appropriately if any problems arise that could make driving
hazardous, including a potentially short-term but serious change in health status, such
as a systemic infection, significant electrolyte abnormality, ischemic coronary event
or symptoms such as weakness or hypotension that occur while adjusting to a new
dialysis regimen.
20.2 Dialysis
Patients with end-stage renal disease maintained on hemodialysis or peritoneal dialysis
can drive any class of motor vehicle, provided they possess adequate cognitive and
sensorimotor ability.
Drivers considering trips must take into account their access to dialysis treatments
and supplies.
20.2.1 Hemodialysis
Patients undergoing facility-based hemodialysis may have multiple
cardiovascular and diabetic comorbidities. In assessing their fitness to drive,
physicians should evaluate these patients individually for the presence of
relevant comorbidities, medications and adverse symptoms associated with
their treatments.
Few studies provide clinicians with validated tools to identify dialysis patients
who may not be fit to drive. A study of 186 patients receiving dialysis in
the United States (87% hemodialysis, 12% peritoneal dialysis) revealed
that 40% of surveyed patients were “not comfortable driving” (Vats and
Duffy, 2010). However, 42% of this group still drove, with 48% reporting
accidents. Approximately three-quarters of patients who admitted to feeling
uncomfortable driving reported 1 or more symptoms of weakness, dizziness or
difficulty with coordination after a hemodialysis session.
Varela et al. (2015) analyzed the accuracy of an instrument developed by the
American Automobile Association and the American Medical Association to
assess the safety of geriatric drivers, as applied specifically to 106 dialysis
patients (72% hemodialysis, 34% peritoneal dialysis). The “Am I a Safe Driver?”
checklist asks patients to answer 24 specific questions (1 was omitted).
The authors concluded that answering “YES” to 2 or more questions on the
checklist was potentially useful for identifying patients at high risk for driving
impairment (84% sensitivity, 58% specificity) but required confirmation
by other methods, as nearly half of “screen-positive” patients may still be
considered safe to drive.
These studies suggest that (1) a substantial proportion of patients receiving
dialysis (especially hemodialysis) may have episodes when they are not fit
to drive, especially after dialysis sessions; and (2) the “Am I a Safe Driver?”
checklist may be useful for identifying patients who require further evaluation.
However, data are insufficient to mandate regular screening of dialysis patients
with this instrument or available alternatives.
Dialysis staff may consider asking patients how they plan to return home in
the event of a highly symptomatic hemodialysis session and discussing
alternative arrangements for patients who had planned to drive but do not
appear well enough.
Musculoskeletal disabilities
Alert
21.1 Overview
Musculoskeletal injury or disability can often have an impact on a patient’s driving
ability. In assessing a patient, it is important to establish from the start whether the
patient drives a vehicle with manual or automatic transmission and whether the injury or
disability is temporary or permanent.
All jurisdictions have established procedures to evaluate drivers whose medical condition
is incompatible with medical standards, but who claim to be able to compensate and
drive safely despite their condition. In addition to adapting one’s driving technique (e.g.,
by lowering speed or keeping a greater distance between vehicles), there are many ways
to adapt a vehicle for various types of physical disability. A driver in this s ituation, who is
able to demonstrate that his or her driving remains safe, may be granted an exemption
by the licensing authority. Periodic checks may be required by the licensing authority to
validate the driver’s maintenance of the ability to drive safely. A change in the driver’s
medical condition may necessitate a new evaluation.
21.2 Assessment
Musculoskeletal conditions differ in etiology and the severity of physical impairment.
However, all can have an impact on physical function, which may in turn have a negative
impact on driving.
Safe driving requires both hands to be firmly on the steering wheel, except as required
to operate other controls, and the ability to solidly grip the manual gear shift, when and
where applicable. It also requires the ability to use the lower right leg to operate the
accelerator pedal appropriately and to operate the brake pedal with sufficient speed and
force to brake in an emergency, and the lower left leg to the same degree to operate the
clutch, in the case of a vehicle with manual transmission.
Few studies have investigated the relation between specific musculoskeletal conditions
and the risk of motor vehicle crashes or their impact on driving ability. Most of these
22.1 Overview
There are a number of medical conditions that may influence driver fitness that have not
been discussed in detail in previous sections of this guide. This section lists some of these
conditions meriting special attention.
22.2 Obesity
Although most patients with obesity will be able to continue driving, morbid obesity may
be incompatible with driving certain vehicles. For example, a professional truck or bus
driver must perform certain tasks associated with the vehicle’s security that may involve
clambering on or under the vehicle, tasks that a person with morbid obesity will be
unable to accomplish.
Many patients with obesity report that they are unable to wear seat belts; however, most
vehicles can accommodate seat belt extensions. For patients with severe obesity, it may
be necessary to consider deactivating the airbags to avoid inadvertently deploying the
airbag and thereby causing injury.
22.3 Delirium
Delirium, a rapid-onset change in cognition, may be associated with many of the
conditions reviewed elsewhere in this guide. Delirium can present with obvious
symptoms, such as hallucinations, and altered level of consciousness, often of fluctuating
degree. Delirium can also present with more subtle subsyndromal symptoms, such as
poor concentration and slow mentation. As patients recover from the obvious symptoms
of delirium, they may temporarily experience a phase of more subtle symptoms that may
still be pertinent to their ability to resume driving. The hypoactive subtype of delirium is
commoner than the hyperactive type and is often overlooked.
For more information on the criteria on delirium see the article by David K. Conn and
Susan Lieff. Diagnosing and managing delirium in the elderly. Canadian Family Physician,
January 2001. Available: www.ncbi.nlm.nih.gov/pmc/articles/PMC2014716/
To screen for delirium, some clinicians employ the Confusion Assessment Method https://
consultgeri.org/try-this/general-assessment/issue-13.pdf.
Miscellaneous conditions that may affect fitness to drive fitness to drive 112
Consequently, it is important for physicians and allied health care professionals to include
counselling on driving in their routine advice to such patients. This is especially true for
chronic conditions such as diabetes mellitus, where continuing to live a relatively normal
life is possible, if reasonable precautions are observed. Unfortunately, unless patients are
counselled on how to compensate for their condition, they may engage in behaviour that
is incompatible with safe driving.
More generally, physicians are reminded that an evaluation of fitness to drive (in
accordance with the principles discussed in section 2, Functional assessment — emerging
emphasis) is essential for any patient, regardless of age, who is manifesting difficulty in
maintaining activities that were part of the daily routine before the medical condition
arose. In this context, the physician should consider not only the standard activities
of daily living but also additional activities that the patient previously enjoyed and has
abandoned because of the medical condition, such as model making, reading, embroidery
and knitting.
Alert
Any advice to the patient with respect to driving should be noted in the medical record.
23.1 Overview
Both anesthesia and surgery can have a significant, although temporary, effect on
driving ability.
23.3 Procedures
Any outpatient surgical or diagnostic procedure may render patients temporarily unfit to
drive. Instructions to patients should include the necessity to provide a means to return
home and the advisability of avoiding driving until all the effects of the procedure have
resolved. Patients who do not have a means to return home should not undergo the
planned procedure until arrangements have been made.
Alert
There are no medical circumstances that justify exemption from wearing a seat belt.
24.1 Overview
All provinces and territories have legislation that requires every occupant of a vehicle to
wear a seat belt. All children (including infants) must be secured in appropriate
child seats.
Airbags are safety devices that supplement the protection provided by seat belts. They
are installed in the steering wheel and front passenger console of most newer-model
cars, although there are still vehicles without them. If airbags are present in a vehicle,
infants and children age 12 and under should sit only in the back seat of the vehicle. In
cars without airbags, the back seat is still safest in the event of a crash, as it is likely to be
furthest from the point of impact.
A consumer can choose to have the airbag(s) in a vehicle deactivated if the consumer,
or a user of the vehicle, is in one of the circumstances listed in section 24.3. Physician
documentation of the circumstance is not required. The applicant must indicate on
the form that he or she has read the airbag deactivation brochure and understands
the benefits and risks of deactivating the airbag. An application form for deactivation
of airbag(s) is available from Transport Canada (see “How to obtain a ‘Declaration of
Requirement for Air Bag Deactivation’ Form” at http://wwwapps.tc.gc.ca/Corp-Serv-
Gen/5/forms-formulaires/download/13-0140_BO_PD.
24.4 Literature
The literature on the use of seat belts and airbags is vast. Research establishing the
beneficial effects of seat belts was conducted mainly over the period 1970–1985. Airbag
research is more recent but has followed the same progression. The benefits of restraint
systems for vehicle occupants is now taken for granted, and current research is oriented
toward improving the restraints and persuading non-users to buckle up (“click it or ticket”
initiatives). For further information, contact: Road and Motor Vehicle Safety, Transport
Canada. www.tc.gc.ca/roadsafety
Alert
25.1 Overview
Operating a motorcycle (Class 6) or an off-road vehicle, including a snowmobile, demands
a higher level of physical fitness and different driving skills than driving a private
passenger vehicle.
As long as off-road vehicles are not driven on provincial roads, they do not need licence
plates, and their use is not subject to any regulation.
Nevertheless, drivers of motorcycles and off-road vehicles should be advised to wear
protective helmets at all times. There are no valid medical reasons for a driver or a
passenger not to wear a helmet. A person who is incapable of wearing a helmet should
be encouraged to find another mode of transportation.
25.2 General
Motorcycle operators should be expected to meet the medical standards for private
vehicle (Class 5) drivers in every respect. Medical disabilities that might be safely
overlooked for a private vehicle driver may be incompatible with the safe operation
of a motorcycle.
Driving a motorcycle requires the full use of all 4 limbs and good balance. A motorcycle
driver must be able to maintain a strong grip with both hands, as this is required for the
use of handlebar controls. A driver must keep both hands on the handlebars.
25.3 Specific
• Angina: Exposure to cold and cold winds can trigger an angina attack in
susceptible patients.
• Asthma: Exposure to cold and cold winds may trigger “cold” anaphylaxis and
bronchoconstriction.
• Carotid sinus sensitivity: This condition is dangerous because the tight restraining
straps on most protective headgear may place pressure on the carotid sinus.
• Cervical spine: Motorcycle drivers with a history of cervical spine injuries or instability
should be assessed for the ability to maintain a safe riding posture without neurologic
compromise.
• Permanent tracheostomy: Drivers with a permanent tracheostomy should have some
form of protection from the effects of the air stream.
117 CMA Driver’s Guide — 9th Edition
Section 26:
Aviation*
Alert
Physicians are required by law to report to regional aviation medical officers of Transport
Canada any pilots, air traffic controllers or flight engineers with a medical condition that
could affect flight safety. Common conditions requiring mandatory reporting are listed in
this section.
26.1 Overview
For the purpose of this guide, all references to “pilots” will apply equally to air traffic
controllers and flight engineers, unless otherwise stated. As well, “pilots” includes airline
transport pilots, commercial pilots, private pilots, student pilots, recreational pilots, etc.
The types of aircraft they may fly include fixed-wing planes (jet and propeller-driven),
helicopters, balloons, gliders, ultra-lights and gyroplanes.
Pilots are all holders of Canadian aviation documents that impose standards of medical
fitness. Regulation of pilots is under federal legislation (not provincial, as is the case for
motor vehicle drivers).
Periodic examinations of pilots are performed by physicians (civil aviation medical
examiners) appointed by the minister of transport. Episodic care of pilots is often by
community physicians.
Before being examined, all pilots must inform the physician that they hold an aviation
licence or permit. When pilots are informed that they have a condition (or are prescribed
treatment) that might make it unsafe for them to perform their duties, they must
“ground” themselves temporarily.
A physician diagnosing a condition that might affect flight safety must report the
condition to the medical advisors of Transport Canada.
Aviation* 118
safety, inform a medical adviser designated by the Minister forthwith of that opinion
and the reasons therefor.
2. The holder of a Canadian aviation document that imposes standards of medical or
optometric fitness shall, prior to any medical or optometric examination of his/her
person by a physician or optometrist, advise the physician or optometrist that he/she
is the holder of such a document.
3. The Minister may make such use of any information provided pursuant to subsection
(1) as he considers necessary in the interests of aviation safety.
4. No legal, disciplinary or other proceedings lie against a physician or optometrist for
anything done by him in good faith in compliance with this section.
5. Notwithstanding subsection (3), information provided pursuant to subsection (1) is
privileged and no person shall be required to disclose it or give evidence relating to it
in any legal, disciplinary or other proceedings and the information so provided shall
not be used in any such proceedings.
6. The holder of a Canadian aviation document that imposes standards of medical or
optometric fitness shall be deemed, for the purposes of this section, to have con-
sented to the giving of information to a medical adviser designated by the Minister
under subsection (1) in the circumstances referred to in that subsection.
The relevant section of the Aeronautics Act (R.S.C., 1985, c. A-2) is “Medical and
Optometric Information,” available online at: www.laws-lois.justice.gc.ca/eng/acts/A-2/
page-20.html#h-25
26.3 Reporting
If uncertain whether a condition might affect flight safety, the physician can discuss the
case with a regional aviation medical officer (RAMO), as listed in section 26.20. At this
stage, the physician need not identify the pilot.
If certain that a condition might affect flight safety, the physician must
• Advise the pilot.
• Report by phone to a RAMO at a civil aviation medicine regional office (see section
26.20). The report will be confidential, physician-to-physician and privileged.
• Confirm information in writing (by facsimile). This report is confidential and privileged.
Once a report under section 6.5 of the Aeronautics Act has been made, it is the RAMO’s
responsibility to take further action. Although Transport Canada may use the reported
information as necessary to ensure aviation safety, the report itself cannot be used as
evidence in any legal, disciplinary or other proceedings.
Physicians may wish to contact the CMPA for advice should they have questions about
their reporting obligation.
Aviation* 120
26.6 Vision
Conditions where visual impairment is temporary or vision is temporarily affected by the
use of medications need not be reported. Pilots should be warned not to fly until normal
vision has returned.
Reporting the following conditions is mandatory:
• diplopia
• monocularity
• visual fields — including partial loss of a visual field or significant scotomata
• eye injuries or retinal detachment
• cataract surgery
• surgical correction of myopia following radial keratotomy, photorefractive keratecto-
my, laser-assisted in-situ keratomileusis or other refractive eye surgery.
Aviation* 122
• sinus node dysfunction or sick sinus syndrome — symptomatic bradycardia
or sinus node dysfunction
• heart block and bundle branch blocks — second- or third-degree heart block
or the development of a new right or left bundle branch block
• pacemakers — pilots requiring a pacemaker or automatic implantable
defibrillation devices.
Aviation* 124
• type 2 diabetes — treated with oral or injected hypoglycemic drugs and/
or insulin therapy; changes in type or dose of medication; hypoglycemic attacks
requiring treatment
• thyroid and parathyroid disease — initial diagnosis of these conditions; once the
condition is stable, only significant changes in treatment
• pituitary disease — initial diagnosis and investigation; any mass compromising the
optic chiasm must be reported
• adrenal disease — initial diagnosis and investigation
• anabolic steroids.
26.17 Tumours
Reporting of the following is mandatory:
• any tumour that limits the ability of a pilot to perform safely
• tumours that may metastasize to the brain.
26.19 Drugs
• Substance abuse: Pilots who abuse or are addicted to alcohol or other chemical
substances must be reported.
• Alcohol: By law, no one may function as a crew member of an aircraft (or work as an
air traffic controller) if he or she has consumed alcohol within the previous 8 hours.
After heavy drinking, even this interval will be too short because alcohol can affect
balance and orientation for up to 48 hours.
• Illicit drugs: Marijuana and other illicit drugs impair judgment and coordination; the
effects may last for prolonged periods.
• Prescription drugs: Discuss in detail the side effects of any medication that is pre-
scribed or recommended to pilots. For example, minor side effects on visual accom-
modation, muscular coordination, the gastrointestinal tract or tolerance to accelera-
tion (increased gravity) may be more serious when they occur in flight. If in doubt, the
physician should discuss the medication with the RAMO.
• Over-the-counter drugs: Generally, pilots are advised to avoid taking any medication
within 12 hours (or, if longer-acting, within about 5 half-lives) before flight if pharma-
cologic effects may affect flying. Although there are exceptions to this rule, caution
is advised.
• Anesthetics (general and local): There is no general rule about how long a pilot should
be grounded after receiving a general anesthetic. It depends on the type of surgery,
Aviation* 126
premedication and the anesthetic agent. Physicians should be aware that the effect
of some anesthetics may take days to wear off, and caution is recommended. A RAMO
can answer enquiries on this subject.
In cases where local anesthetics have been used for extensive procedures, flying should
be restricted for a minimum of 24 hours.
26.20 Contacts
Civil Aviation Medicine headquarters
Civil Aviation Medicine
Transport Canada
330 Sparks St.
Place de Ville, Tower C, Room 617
Ottawa ON K1A 0N8
Tel 613-990-1311
Toll free: 800-305-2059
Fax 613-990-6623
www.tc.gc.ca/CivilAviation/Cam/
Civil Aviation Medicine Branch offices (Regional aviation medical officers RAMO)
See https://tc.gc.ca/eng/civilaviation/opssvs/regions-139.htm for complete list of
branch offices and current contact information.
Atlantic Region – New Brunswick, Prince Edward Island, Nova Scotia, and
Newfoundland & Labrador
PO Box 42
Moncton, New Brunswick
E1C 8K6
Telephone: 1-800-305-2059
E-mail: tc.aviationservicesatl-servicesaviationatl.tc@tc.gc.ca
Quebec Region
700 Leigh Capreol, Zone 4E, NA Dept.
Dorval, Quebec
H4Y 1G7
Ontario Region
4900 Yonge Street, 4th Floor
North York, Ontario
M2N 6A5
Telephone: 1-800-305-2059
Fax: (416) 952-0196 / 1-877-822-2129
Fee Payment: (416) 952-0400 / 1-800-305-2059
E-mail: tc.aviationservicesont-servicesaviationont.tc@tc.gc.ca
Aviation* 128
Section 27:
Railway*
Alert
• “Railway” includes national passenger and freight trains, as well as commuter and
privately owned trains.
• Railway employees in Safety Critical Positions operate or control the movement of
trains.
• Physicians are required by law to notify the railway company’s chief medical officer
if a person in a Safety Critical Position has a medical condition that could affect
railway safety.
• Railway Medical Guidelines to determine medical fitness for duty are available at
www.railcan.ca/publications/rule_handbook
27.1 Overview
This section concerns assessing medical fitness for duty of a person occupying a Safety
Critical Position on a railway. These employees operate or control the movement of
trains. They are required to meet the medical fitness standards of the Railway Medical
Guidelines. Assessments regarding fitness for duty, as well as episodic medical care, are
usually done by community physicians.
A person in a Safety Critical Position must identify himself or herself as such to a physician
before any examination.
The occupations designated as Safety Critical Positions may vary between railways, but
typically include
• locomotive engineer
• conductor
• assistant conductor (brakeperson)
• yard foreman or yardperson
• rail traffic controller (train dispatcher).
In addition, any employee or contractor who is required to perform any of these
functions is considered to occupy a Safety Critical Position.
_____________________________________________________________________________
*Prepared by the Medical Advisory Group of the Railway Association of Canada to facilitate public safety in rail
freight and passenger train operations across Canada.
27.3 Reporting
According to the Railway Safety Act, a physician must notify a railway company’s chief
medical officer if a person occupying a Safety Critical Position has a medical condition
that could be a threat to safe railway operations. Contact information is listed in section
27.8, Contacts.
Physicians may wish to contact the CMPA for advice should they have questions about
their reporting obligation.
Railway* 130
• Cognition. The person must have normal function in terms of
• alertness
• judgment
• concentration
• comprehension of concurrent written, verbal and signal-based communication
• awareness of the environment and other members of the work crew
• vigilance for prolonged periods.
• Special senses
• Vision, including colour perception, must meet railway industry standards. Individu-
als not meeting colour vision testing standards are required to undergo further
assessment by a specific test developed by the railway industry.
• Hearing must meet railway industry standards. Despite noisy environments, railway
workers must be able to receive, comprehend and transmit communications via a
variety of means (e.g., radio, telephone, face to face).
• Ability to tolerate and function in a stressful work environment, which includes a
highly variable work shift.
• Must not be subject to sudden impairment of physical or mental capabilities.
• Medical fitness for duty also takes into consideration medical conditions including
treatment and medications, both past and present, that could result in
• sudden or gradual impairment of cognitive function including alertness, judgment,
insight, memory and concentration
• impairment of senses
• significant impairment of musculoskeletal function
• other impairment that is likely to constitute a threat to safe railway operations.
Note: Railway Medical Guidelines (see section 27.7, Resources) include the following
conditions to assist physicians regarding Safety Critical Positions:
• cardiovascular disorders
• diabetes
• epilepsy or other epileptic seizures
• hearing
• mental disorders
• severe sleep apnea
• substance use disorders
• therapeutic opioids
• vision.
27.7 Resources
A copy of the Canadian Railway Medical Rules Handbook (which includes the current
Railway Medical Guidelines) is available on the Railway Association of Canada website
(www.railcan.ca/publications/rule_handbook).
27.8 Contacts
Railway Association of Canada
Tel 613-564-8088
Railway* 132
Class 1 Railways
Canadian Pacific
Tel 866-876-0879 (toll free)
CN
Tel 514-399-5690
Other Railways
VIA Rail Canada
Tel 888-842-7245
Contact numbers for BNSF and other Regional Short Line Railroads can be obtained from
the Railway Association of Canada.
Tel 613-564-8088
Appendix A 134
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2006;41(3):61-4.
National Highway Traffic Safety Administration (US). Driver fitness medical
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lib/31000/31100/31148/6061_MedicalReviewGuide_10-1_v2a.pdf (accessed 2016 Apr. 7).
Third Canadian conference on diagnosis and treatment of dementia. 146 approved
recommendations – final July 2007. Available: www.cccdtd.ca/pdfs/Final_
Recommendations_CCCDTD_2007.pdf (accessed 2016 Apr. 7).
Section 6 — Drugs
American Psychiatric Association (APA). Diagnostic and Statistical Manual of Mental
Disorders (4th ed., text rev.). Washington (DC): The Association; 2000.
American Psychiatric Association (APA). Diagnostic and Statistical Manual of Mental
Disorders (5th ed.). Washington (DC): The Association; 2013.
American Society of Addiction Medicine (ASAM). Public policy statement: Definition of
addiction. Chevy Chase (MD): The Society; 2011. Available: www.asam.org/docs/publicy-
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(accessed 2016 Apr. 7).
American Society of Addiction Medicine (ASAM). White Paper on State-Level Proposals
to Legalize Marijuana. Chevy Chase (MD): The Society; 2012. Available: www.asam.
org/docs/publicy-policy-statements/state-level-proposals-to-legalize-marijuana-
final2773DD668C2D.pdf (accessed 2016 Apr. 9).
Appendix A 136
BC Ministry of Public Safety and Solicitor General, Office of the Superintendent of Motor
Vehicles. Chapter 29: Psychotropic drugs. In: 2010 BC guide in determining fitness to
drive. Victoria (BC): The Ministry; 2010. p. 364-76. Available: www2.gov.bc.ca/assets/gov/
driving-and-transportation/driving/publications/2010-guide-in-determining-fitness-to-
drive.pdf (accessed 2016 Apr. 7).
Brady JE, Li G. Trends in alcohol and other drugs detected in fatally injured drivers in the
United States, 1999-2010. Am J Epidemiol. 2014;179(6):692-9.
Canadian Council of Motor Transport Administrators. Determining Driver Fitness in
Canada: Part I: A Model for the Administration of Driver Fitness Programs and Part II: CCMTA
Medical Standards for Drivers. Ottawa (ON): The Council; 2015. Available: http://ccmta.ca/
images/publications/pdf/CCMTA_Medical_Standards_Dec_1_2015_final_clean_copy.pdf
(accessed 2016 Apr. 7).
Carr DB, Schwartzberg JG, Manning L, Sempek J. Chapter 9: Medical conditions and
medications that may affect driving. In: Physician’s guide to assessing and counseling older
drivers. 2nd ed. Chicago (IL): American Medical Association; National Highway Traffic
Safety Administration (US); 2010. See section 13, Medications. p. 178-84. Available: www.
nhtsa.gov/staticfiles/nti/older_drivers/pdf/811298.pdf (accessed 2016 Apr. 7).
Chang CM, Wu EC, Chen CY, Wu KY, Liang HY, Chau YL, Wu CS, Lin KM, Tsai HJ.
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Dassanayake T, Michie P, Carter G, Jones A. Effects of benzodiazepines, antidepressants
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Section 7 — Aging
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for action for promoting safe driving among older drivers in Canada.
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• FIND an OT: https://www.find-an-ot.ca/
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Appendix A 142
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memory performance with rTMS in healthy subjects and individuals with mild cognitive
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Section 12 — Vision
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illness on crash involvement of motor vehicle drivers. 2nd ed. Report 300. Victoria, Australia:
Monash University Accident Research Centre; 2010. Available: www.monash.edu.au/miri/
research/reports/muarc300.html (accessed 2016 Apr. 7).
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drivers. Traffic Inj Prev. 2013;14(5):477-85.
Johnson CA, Wilkinson ME. Vision and driving: The United States. J Neuro-Ophthalmol.
2010;30(2):170-6.
Kaleem MA, Munoz BE, Munro CA, Gower EW, West SK. Visual characteristics of elderly
night drivers in the Salisbury Eye Evaluation Driving Study. Investig Ophthalmol Vis Sci.
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McCarthy DP, Mann WC. Process and outcomes evaluation of screening programs for
older drivers: the Assessment of Driving-Related Skills (ADReS) older-driver screening tool.
Washington (DC): National Highway Traffic Safety Administration (US); 2009. Available:
www.nhtsa.gov/DOT/NHTSA/Traffic%20Injury%20Control/Articles/Associated%20
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Owsley C, McGwin G Jr. Vision and driving. Vis res. 2010;50(23): 2348-61.
Yazdan-Ashoori P, Ten Hove M. Vision and driving: Canada. J Neuro-Ophthalmol.
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mild traumatic brain injury and persistent symptoms. Can Fam Physician. 2012;58(3):257-
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Marshall SC, Molnar F, Man-Son-Hing M, Blair R, Brosseau L, Finestone HM, et al.
Predictors of driving ability following stroke: a systematic review. Top Stroke Rehabil.
2007;14(1):98-114.
Preece MH, Horswill MS, Geffen GM. Assessment of drivers’ ability to anticipate traffic
hazards after traumatic brain injury. J Neurol Neurosurg Psychiatry. 2011;82(4):447-51.
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Appendix A 150
Appendix B
Fitness to drive issues and risk management
Message from the Canadian Medical Protective Association (Revised 2012)*
Most Canadians depend on their vehicles and their ability to drive to assist them with
the many activities in their lives. Telling patients that their medical condition may make
it too dangerous for them to drive is a difficult conversation for physicians to have,
and one that is equally difficult for patients to hear.
A report from a physician that results in the loss of the right to operate a vehicle can
provoke strong feelings and have serious personal and financial consequences for the
individuals involved. Physicians need to carefully consider the variety of issues associated
with reporting (or not reporting) a patient with a medical condition to a motor vehicle
licensing authority. The final decision can have implications, some of them serious,
for both the physician and patient.
In most jurisdictions, legislation requires physicians to report any patient who, in their
opinion, has a medical condition that may make it dangerous for the patient to drive.
In a few jurisdictions, reporting is discretionary. The ultimate decision whether to restrict
driving privileges is always made by the provincial or territorial motor vehicle licensing
authority, not by the physician. All jurisdictions include statutory protection from liability
in civil actions for making a report in good faith.
The Canadian Medical Protective Association regularly reviews its experience in assisting
members in matters related to fitness to drive. These reviews have identified 3 principal
themes. The first is allegations in legal actions that a physician failed to report a patient
as unfit to drive because of a medical condition. The second is complaints from a patient
that a report has been made to a motor vehicle licensing authority. The third relates to
patient complaints about the physician’s refusal to support an application to restore
driving privileges.
Failure to report
Following a motor vehicle accident caused by an unfit driver, the allegation may be that
the physician failed to advise the patient not to drive, and/or failed to make a necessary
report to the motor vehicle licensing authority. In these cases, the injured party may
initiate a civil legal action against the patient (driver), the physician, or both. Physicians
have sometimes been found liable for damages under these circumstances.
Physicians should be familiar with the legislative criteria for reporting in their jurisdiction
and assess the patient’s condition in light of those statutory parameters.
_____________________________________________________________________________
* Used with the permission of the Canadian Medical Protective Association (CMPA)
Licence reinstatement
In some cases, patients who have had their license suspended may complain that their
physician did not assist in their request to have their license reinstated. Prior to assisting
patients with such requests, physicians should carefully evaluate whether there has
been significant change in the patient’s clinical condition that led to the original report.
Physicians should only support a patient’s application for license reinstatement if they
feel able to comment based on the available information and their own expertise. It may
be helpful in some cases to consult with a colleague or obtain a functional assessment.
Physicians should document their clinical reassessments in the medical record and, where
appropriate, document and explain to the patient why they are unable to support the
patient’s request for license reinstatement.
Appendix B 152
based on the clinical assessment of risk posed by the patient. Consult with colleagues
and/or obtain functional assessments, if appropriate.
• In keeping with confidentiality and privacy obligations, limit the report to the informa-
tion prescribed by the legislation and that necessary to complete the report.
• It is usually beneficial to discuss your decision to report with the patient, including
the rationale for reporting, the nature of the report and the legal obligation to report.
Talk to the patient about your findings and try to help the patient understand the
safety reasons for your report.
• Irrespective of the duty to report, physicians should advise the patient not to drive
while permanently or temporarily disabled.
• Document your discussions, warnings, and advice to the patient, as well as your
decision about whether or not to make a fitness to drive report.
• Prior to supporting a request to help reinstate a patient’s licence, carry out careful
clinical reassessments, and document your findings and recommendations in the
medical record. Physicians should not feel compelled, and should refrain from, provid-
ing information they do not feel qualified or able to comment on. Consult with
colleagues and/or obtain functional assessments, if appropriate.
The CMPA recommends physicians consult its publications related to reporting on
fitness to drive: “Reporting patients with medical conditions affecting their fitness to
drive” and “When the loss of independence can save a life!”, which are both available on
the CMPA website (www.cmpa-acpm.ca). CMPA members are also encouraged to contact
the Association for advice and guidance from experienced medical officers on their
reporting duties.
Alert
GE questionnaire
• Have you ever felt you should Cut down on your drinking?
• Have people Annoyed you by criticizing your drinking?
• Have you ever felt bad or Guilty about your drinking?
• Have you ever had a drink first thing in the morning to steady your nerves or to get rid of a
hangover (Eye opener)?
Scoring
Item responses on the CAGE are scored 0 or 1, for a total score of 0–4. A patient with a
score of 1 or more requires further assessment. A total score of 2 or greater is considered
clinically significant for having an alcohol use disorder.
Developed by Dr. John Ewing, founding director of the Bowles Center for Alcohol
Studies, University of North Carolina at Chapel Hill, CAGE is an internationally used
assessment instrument for identifying alcoholics. It is particularly popular with primary
caregivers. CAGE has been translated into several languages, and its robustness makes
it a practical tool for screening for problems related to drug use and other addictive
behaviours.
The CAGE questions can be used in the clinical setting using informal phrasing. It
has been demonstrated that they are most effective when used as part of a general
health history and should NOT be preceded by questions about how much or how
frequently the patient drinks (see DL Steinweg and H Worth. Alcoholism: the keys to
the CAGE. American Journal of Medicine 1993;94:520–3). The exact wording that can
be used in research studies can be found in JA Ewing. Detecting alcoholism: the CAGE
questionnaire. JAMA 1984;252:1905–7.
Appendix C 154
Appendix D
_____________________________________________________________________________
*Babor TF, Higgins-Biddle JC, Sanders JB, Monteiro MG. AUDIT — alcohol use disorders identification test:
guidelines for use in primary care. Geneva: World Health Organization. Geneva; 2001. WHO/MSD/MSB/01.6a.
Reprinted with permission.
5. How often during the last year have you failed to do what was normally expected
from you because of drinking?
(0) Never
(1) Less than monthly
(2) Monthly
(3) Weekly
(4) Daily or almost daily
6. How often during the last year have you needed a first drink in the morning to get
yourself going after a heavy drinking session?
(0) Never
(1) Less than monthly
(2) Monthly
(3) Weekly
(4) Daily or almost daily
7. How often during the last year have you had a feeling of guilt or remorse after
drinking?
(0) Never
(1) Less than monthly
(2) Monthly
(3) Weekly
(4) Daily or almost daily
Appendix D 156
8. How often during the last year have you been unable to remember what happened
the night before because you had been drinking?
(0) Never
(1) Less than monthly
(2) Monthly
(3) Weekly
(4) Daily or almost daily
9. Have you or someone else been injured as the result of your drinking?
(0) No
(2) Yes, but not in the last year
(4) Yes, during the last year
10. Has a relative or friend or a doctor or another health worker been concerned about
your drinking or suggested you cut down?
(0) No
(2) Yes, but not in the last year
(4) Yes, during the last year
Record total of items here _________
If total is greater than recommended cut-off, consult User’s Manual available at:
http://www.talkingalcohol.com/files/pdfs/WHO_audit.pdf
ALBERTA
Driver Fitness and Monitoring Branch
Infrastructure and Transportation
Government of Alberta
Main Floor, Twin Atria Building
4999–98 Avenue
Edmonton AB T6B 2X3
Tel (780) 427-8230 (toll free in Alberta 310-0000)
Fax (780) 422-6612
www.transportation.alberta.ca/2567.htm
BRITISH COLUMBIA
Office of the Superintendent of Motor Vehicles
RoadSafetyBC
PO Box 9254, Stn Prov Gov
Victoria BC V8W 9J2
Tel (250) 387-7747
Toll free (855) 387-7747
Fax (250) 387-4891
www2.gov.bc.ca/gov/content/transportation/driving-and-cycling/driver-medical/driver-
medical-fitness
_____________________________________________________________________________
Appendix E 158
Manitoba Public Insurance
Medical Records
Cityplace Service Centre
234 Donald Street
Box 6300
Winnipeg MB R3C 4A4
Tel (204) 985-1900
Toll free (866) 617-6676
Fax (204) 953-4992
www.mpi.mb.ca/en/DL/DL/Outlets/Pages/other-outlets.aspx
NEW BRUNSWICK
Registrar of Motor Vehicles
Department of Public Safety
Motor Vehicle Branch
364 Argyle Street
PO Box 6000
Fredericton NB E3B 5H1
Tel (506) 453-2410
Fax (506) 453-7455
http://www2.gnb.ca/content/gnb/en/services/services_renderer.200814.Motor_Vehicle_
Registration.html
NOVA SCOTIA
Transportation and Infrastructure Renewal, Road Safety Programs
1505 Barrington Street, 9th floor
North Halifax, NS B3J 3K5
Tel (902) 424-5732
Fax (902) 424-0772
novascotia.ca/sns/rmv/licence/medicals.asp
NUNAVUT
Motor Vehicles Division
Department of Economic Development and Transportation
Government of Nunavut
PO Box 10
Gjoa Haven NU X0B 1J0
Tel (867) 360-4615
Fax (867) 360-4619
gov.nu.ca/edt/faq/where-can-i-get-drivers-licence
Appendix E 160
ONTARIO
Driver Improvement Office
Medical Review Section
Ministry of Transportation
77 Wellesley Street
Box 589
Toronto ON M7A 1N3
Tel (416) 235-1773
Toll free (800) 268-1481
Fax (416) 235-3400 or (800) 304-7889
Email: DriverImprovementOffice@ontario.ca
www.mto.gov.on.ca/english/dandv/driver/medical-review/physicians.shtml
QUEBEC
Service de l’évaluation médicale et du suivi du comportement
Société de l’assurance automobile du Québec
333, boul. Jean-Lesage
CP 19600
Québec QC G1K 8J6
Tel (418) 643-5506; outside Quebec (800) 561-2858
Fax (418) 643-4840
www.saaq.gouv.qc.ca
YUKON
Driver Sanctions Coordinator
Government of Yukon
Motor Vehicles Branch (W-22)
Department of Highways and Public
Works
Box 2703
Whitehorse YT Y1A 2C6
Tel (867) 667-3563
Fax (867) 393-6220
Email: motor.vehicles@gov.yk.ca
www.hpw.gov.yk.ca/mv/
Appendix E 162
Appendix F
Canadian Cardiovascular Society’s risk of harm formula*
The risk of harm (RH) to other road users posed by the driver with heart disease is
assumed to be directly proportional to the following:
• time spent behind the wheel or distance driven in a given time period (TD)
• type of vehicle driven (V)
• risk of sudden cardiac incapacitation (SCI)
• the probability that such an event will result in a fatal or injury-producing
accident (Ac).
Expressing this statement as Formula 1:
RH = TD x V x SCI x Ac
Fewer than 2% of reported incidents of driver sudden death or loss of consciousness
have resulted in injury or death to other road users or bystanders.1–4 In Formula 1,
therefore, Ac = 0.02 for all drivers.
There is evidence that loss of control of a heavy truck or passenger-carrying vehicle
results in a more devastating accident than loss of control of a private automobile5.
Truckers are involved in only about 2% of all road accidents but in approximately 7.2%
of all fatal accidents.5 In Formula 1, if V = 1 for a commercial driver, then V = 0.28 for a
private driver.
There is no published standard or definition of what level of risk is considered acceptable
in Canada even through this is crucial in the formulation of guidelines based on the
probability of some event occurring in a defined time period. It was necessary, therefore,
to develop such a standard.
For several years, the guidelines of the Canadian Cardiovascular Society, the Canadian
Medical Association, and the Canadian Council of Motor Transport Administrators have
permitted the driver of a heavy truck to return to that occupation following an acute
myocardial infarction provided that he or she is functional class I with a negative exercise
stress test at 7 metabolic equivalents, has no disqualifying ventricular arrhythmias and
is at least 3 months post-infarct. On the basis of available data, however, such a person
cannot be assigned a risk lower than 1% of cardiac death in the next year. The risk of
sudden death would be lower than this, but would be at least partly offset by the risk
of other suddenly disabling events such as syncope or stroke. For such a person, SCI is
estimated to be equal to 0.01 in Formula 1.
_____________________________________________________________________________
*Excerpt from the Canadian Cardiovascular Society Consensus Conference 2003: Assessment of the cardiac patient
for fitness to drive and fly (final report). Adapted with permission from the Canadian Cardiovascular Society.
Appendix F 164
Appendix G
Definition of Addiction
(American Society of Addiction Medicine, 2011)
Appendix G 166
e. A dysfunctional Emotional response.
The power of external cues to trigger craving and drug use, as well as to increase the
frequency of engagement in other potentially addictive behaviors, is also a characteristic
of addiction, with the hippocampus being important in memory of previous euphoric
or dysphoric experiences, and with the amygdala being important in having motivation
concentrate on selecting behaviors associated with these past experiences.
Although some believe that the difference between those who have addiction, and
those who do not, is the quantity or frequency of alcohol/drug use, engagement in
addictive behaviors (such as gambling or spending)3, or exposure to other external
rewards (such as food or sex), a characteristic aspect of addiction is the qualitative
wayin which the individual responds to such exposures, stressors and environmental
cues. A particularly pathological aspect of the way that persons with addiction pursue
substance use or external rewards is that preoccupation with, obsession with and/or
pursuit of rewards (e.g., alcohol and other drug use) persist despite the accumulation of
adverse consequences. These manifestations can occur compulsively or impulsively, as a
reflection of impaired control.
Persistent risk and/or recurrence of relapse, after periods of abstinence, is another
fundamental feature of addiction. This can be triggered by exposure to rewarding
substances and behaviors, by exposure to environmental cues to use, and by exposure to
emotional stressors that trigger heightened activity in brain stress circuits.4
In addiction there is a significant impairment in executive functioning, which
manifests in problems with perception, learning, impulse control, compulsivity, and
judgment. People with addiction often manifest a lower readiness to change their
dysfunctional behaviors despite mounting concerns expressed by significant others in
their lives; and display an apparent lack of appreciation of the magnitude of cumulative
problems and complications. The still developing frontal lobes of adolescents may both
compound these deficits in executive functioning and predispose youngsters to engage
in “high risk” behaviors, including engaging in alcohol or other drug use. The profound
drive or craving to use substances or engage in apparently rewarding behaviors, which
is seen in many patients with addiction, underscores the compulsive or avolitional
aspect of this disease. This is the connection with “powerlessness” over addiction and
“unmanageability” of life, as is described in Step 1 of 12 Steps programs.
Addiction is more than a behavioral disorder. Features of addiction include aspects
of a person’s behaviors, cognitions, emotions, and interactions with others, including
a person’s ability to relate to members of their family, to members of their community,
to their own psychological state, and to things that transcend their daily experience.
Behavioral manifestations and complications of addiction, primarily due to impaired
control, can include:
a. Excessive use and/or engagement in addictive behaviors, at higher frequencies and/
or quantities than the person intended, often associated with a persistent desire for
and unsuccessful attempts at behavioral control;
Appendix G 168
with functional impairments.
Over time, repeated experiences with substance use or addictive behaviors are not
associated with ever increasing reward circuit activity and are not as subjectively
rewarding. Once a person experiences withdrawal from drug use or comparable
behaviors, there is an anxious, agitated, dysphoric and labile emotional experience,
related to suboptimal reward and the recruitment of brain and hormonal stress
systems, which is associated with withdrawal from virtually all pharmacological classes
of addictive drugs. While tolerance develops to the “high,” tolerance does not develop
to the emotional “low” associated with the cycle of intoxication and withdrawal. Thus,
in addiction, persons repeatedly attempt to create a “high”--but what they mostly
experience is a deeper and deeper “low.” While anyone may “want” to get “high”, those
with addiction feel a “need” to use the addictive substance or engage in the addictive
behavior in order to try to resolve their dysphoric emotional state or their physiological
symptoms of withdrawal. Persons with addiction compulsively use even though it may
not make them feel good, in some cases long after the pursuit of “rewards” is not actually
pleasurable.5 Although people from any culture may choose to “get high” from one or
another activity, it is important to appreciate that addiction is not solely a function of
choice. Simply put, addiction is not a desired condition.
As addiction is a chronic disease, periods of relapse, which may interrupt spans of
remission, are a common feature of addiction. It is also important to recognize that
return to drug use or pathological pursuit of rewards is not inevitable.
Clinical interventions can be quite effective in altering the course of addiction. Close
monitoring of the behaviors of the individual and contingency management, sometimes
including behavioral consequences for relapse behaviors, can contribute to positive
clinical outcomes. Engagement in health promotion activities which promote personal
responsibility and accountability, connection with others, and personal growth also
contribute to recovery. It is important to recognize that addiction can cause disability
or premature death, especially when left untreated or treated inadequately.
The qualitative ways in which the brain and behavior respond to drug exposure and
engagement in addictive behaviors are different at later stages of addiction than in
earlier stages, indicating progression, which may not be overtly apparent. As is the case
with other chronic diseases, the condition must be monitored and managed over time to:
a. Decrease the frequency and intensity of relapses;
b. Sustain periods of remission; and
c. Optimize the person’s level of functioning during periods of remission.
In some cases of addiction, medication management can improve treatment outcomes.
In most cases of addiction, the integration of psychosocial rehabilitation and ongoing care
with evidence-based pharmacological therapy provides the best results. Chronic disease
management is important for minimization of episodes of relapse and their impact.
Explanatory footnotes:
1. The neurobiology of reward has been well understood for decades, whereas the
neurobiology of addiction is still being explored. Most clinicians have learned of
reward pathways including projections from the ventral tegmental area (VTA) of
the brain, through the median forebrain bundle (MFB), and terminating in the
nucleus accumbens (Nuc Acc), in which dopamine neurons are prominent. Current
neuroscience recognizes that the neurocircuitry of reward also involves a rich
bi-directional circuitry connecting the nucleus accumbens and the basal forebrain.
It is the reward circuitry where reward is registered, and where the most
fundamental rewards such as food, hydration, sex, and nurturing exert a strong and
life-sustaining influence. Alcohol, nicotine, other drugs and pathological gambling
behaviors exert their initial effects by acting on the same reward circuitry that
appears in the brain to make food and sex, for example, profoundly reinforcing.
Other effects, such as intoxication and emotional euphoria from rewards, derive
from activation of the reward circuitry. While intoxication and withdrawal are well
understood through the study of reward circuitry, understanding of addiction
requires understanding of a broader network of neural connections involving
forebrain as well as midbrain structures. Selection of certain rewards, preoccupation
with certain rewards, response to triggers to pursue certain rewards, and
motivational drives to use alcohol and other drugs and/or pathologically seek other
rewards, involve multiple brain regions outside of reward neurocircuitry itself.
_____________________________________________________________________________
† See ASAM Public Policy Statement on Treatment for Alcohol and Other Drug Addiction, Adopted: May 01, 1980,
Revised: January 01, 2010 (http://www.asam.org/advocacy/find-a-policy-statement/)
‡ see ASAM Public Policy Statement on The Relationship between Treatment and Self Help: A Joint Statement of
the American Society of Addiction Medicine, the American Academy of Addiction Psychiatry, and the American
Psychiatric Association, Adopted: December 01, 1997 (http://www.asam.org/advocacy/find-a-policy-statement/)
Appendix G 170
2. These five features are not intended to be used as “diagnostic criteria” for
determining if addiction is present or not. Although these characteristic features
are widely present in most cases of addiction, regardless of the pharmacology of
the substance use seen in addiction or the reward that is pathologically pursued,
each feature may not be equally prominent in every case. The diagnosis of addiction
requires a comprehensive biological, psychological, social and spiritual assessment
by a trained and certified professional.
3. In this document, the term "addictive behaviors" refers to behaviors that are
commonly rewarding and are a feature in many cases of addiction. Exposure to
these behaviors, just as occurs with exposure to rewarding drugs, is facilitative
of the addiction process rather than causative of addiction. The state of brain
anatomy and physiology is the underlying variable that is more directly causative of
addiction. Thus, in this document, the term “addictive behaviors” does not refer to
dysfunctional or socially disapproved behaviors, which can appear in many cases of
addiction. Behaviors, such as dishonesty, violation of one’s values or the values of
others, criminal acts etc., can be a component of addiction; these are best viewed
as complications that result from rather than contribute to addiction.
4. The anatomy (the brain circuitry involved) and the physiology (the neuro-transmitters
involved) in these three modes of relapse (drug- or reward-triggered relapse vs.
cue-triggered relapse vs. stress-triggered relapse) have been delineated through
neuroscience research.
Relapse triggered by exposure to addictive/rewarding drugs, including alcohol,
involves the nucleus accumbens and the VTA-MFB-Nuc Acc neural axis (the brain's
mesolimbic dopaminergic "incentive salience circuitry"--see footnote 2 above).
Reward-triggered relapse also is mediated by glutamatergic circuits projecting to
the nucleus accumbens from the frontal cortex.
Relapse triggered by exposure to conditioned cues from the environment
involves glutamate circuits, originating in frontal cortex, insula, hippocampus and
amygdala projecting to mesolimbic incentive salience circuitry.
Relapse triggered by exposure to stressful experiences involves brain stress
circuits beyond the hypothalamic-pituitary-adrenal axis that is well known as the
core of the endocrine stress system. There are two of these relapse-triggering brain
stress circuits – one originates in noradrenergic nucleus A2 in the lateral tegmental
area of the brain stem and projects to the hypothalamus, nucleus accumbens,
frontal cortex, and bed nucleus of the stria terminalis, and uses norepinephrine as
its neurotransmitter; the other originates in the central nucleus of the amygdala,
projects to the bed nucleus of the stria terminalis and uses corticotrophin-releasing
Appendix G 172
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