Drug Study

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Name Of Drug Drug Classification Indications Nursing Considerations

Generic Name: Olanzapine -Antipsychotic -Treatment of schizophrenia. - Assess for history of allergy to
-Dopaminergic blocker -Treatment of acute mixed or manic olanzapine.Monitor for the many possible
Trade Name: Zyprexa episodes associated with bipolar 1 disorder drug interactions.
and maintenance of bipolar 1 disorder as
Milligrams: 600mg monotherapy,or combined with lithium or -Encourage patients to void before taking
valproate. the drug to help decrease anticholinergic
Frequency: BID effects of urinary retention.

-Take this drug exactly as prescribed; do


not change dose without consulting your
healthcare provider.

-Urge the client to stop smoking; may


increase drug clearance.

-Urge clients to stop drinking alcohol; may


Contraindications: increase CNS effects.
- Contraindicated with allergy to
olanzapine, myeloproliferative disorders,
severe CNS depression, comatose states,
lactation.-Use cautiously in elderly or
debilitated patients, or with CV or
cerebrovascular disease, dehydration,
seizure disorders, Alzheimer’s disease,
prostate enlargement, narrow-angle
glaucoma, history of paralytic ileus.
Name of Drug Drug Classification Indications Nursing Considerations

Generic Name: Haloperidol -Conventional Antipsychotics -Haloperidol is indicated for a number of -Risk of sudden death, torsades de pointes,
conditions including for the treatment of and prolonged QT interval from off-label IV
Trade Name: Apo-Haloperidol Haldol schizophrenia, for the manifestations of administration of higher than recommended
Haldol Decanoate Haldol LA Peridol psychotic disorders, for the control of tics dose: monitor ECG if administering
and vocal utterances of Tourette’s Disorder intravenously (IV).
Milligrams: 0.5-5 mg in children and adults, for treatment of
severe behaviour problems in children of -Conditions or drugs that prolong QT
Frequency: BID or TID combative, explosive hyperexcitability interval, congenital long QT syndrome.
(which cannot be accounted for by
immediate provocation). -Safety of prolonged administration of 100
mg/day orally not established.

-Avoid use in narrow-angle glaucoma, bone


marrow suppression, and severe
hypotension.

Contraindications: -FDA warning regarding off-label use for


-Severe toxic central nervous system dementia in elderly.
depression or comatose states from any
cause. -Leukopenia/neutropenia and
agranulocytosis were reported; possible
-Hypersensitivity to this drug – risk factors include pre existing low white
hypersensitivity reactions have included blood cell (WBC) count and history of
anaphylactic reaction and angioedema. drug-induced leukopenia/neutropenia.

-Dementia with Lewy bodies. -Severe neurotoxicity manifesting as rigidity


or inability to walk or talk may occur in
patients with thyrotoxicosis also receiving
antipsychotics
Name of Drug Drug Classification Indications Nursing Considerations

Generic Name: Biperiden -Anticholinergic -Parkinsonian syndrome especially to -Monitor Vital signs.
counteract muscular rigidity and tremor;
Trade Name: Akineton, Akidin, Apiden extrapyramidal symptoms. -Avoid activities that require alertness, may
cause dizziness, drowsiness and blurring of
Milligrams: 1mg vision.

Frequency: PRN -Caution patient to rise slowly from sitting


or recumbent position to minimize
orthostatic hypotension.

-Teach patients to use gum, hard candy,


and frequent sips of water to decrease dry
Contraindications: mouth.
Hypersensitivity to biperiden Untreated
narrow-angle glaucoma, mechanical -Reassess patient’s condition when the
stenoses in the GI tract, paralytic medication is expected to take effect.
ileus,megacolon, prostatic adenoma and
diseases that can lead to perilous
tachycardia.

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