List of bestselling drugs

List of bestselling drugs

The following is a list of the top 200 pharmaceutical products ranked by sales in U.S. dollars for 2006.
Rank 2006 Brand Name(s) Generic Name Sales 2006 Change (USDmillions) from 2005 14,385 6,129 Company(ies) Disease/Medical Use First Approval Date Dec-1996 Aug-2000 Patent Expiration [1] [2] Date Nov-2011 Mar-2012

1 2

Lipitor Advair, Seretide Plavix, Iscover

Atorvastatin Fluticasone + Salmeterol Clopidogrel

7% Pfizer 12% GlaxoSmithKline

Cholesterol Asthma

6,057

-5% Bristol-Myers Squibb/Sanofi-Aventis 12% AstraZeneca

Thrombotic events

Nov-1997

Nov-2011

Nexium

Esomeprazole

5,182

Gastrointestinal disorders Hypertension Crohn's disease, Rheumatoid arthritis

Mar-2000

Sep-2007

5 6

Norvasc Remicade

Amlodipine Infliximab

4,866 4,428

3% Pfizer 23% Johnson & Johnson, Schering-Plough, Mitsubishi Tanabe Pharma 20% Amgen 4% Eli Lilly and Company 15% Novartis 18% Johnson & Johnson 26% Amgen 16% Roche, Genentech, Biogen Idec, Chugai Pharmaceutical 8% Wyeth

Jul-1992 Aug-1998

Jul-2006 n/a

7 8 9 10 11 12

Enbrel Zyprexa Diovan Risperdal Aranesp Rituxan, MabThera

Etanercept Olanzapine Valsartan Risperidone Darbepoetin alfa Rituximab

4,379 4,364 4,223 4,183 4,121 3,861

Rheumatoid arthritis Psychosis Hypertension Psychosis Anemia Non-Hodgkins lymphoma, Rheumatoid arthritis Depression, Anxiety disorders Gastrointestinal disorders

Nov-1998 Sep-1996 Dec-1996 Dec-1993 Jun-2001 Nov-1997

Oct-2012 Jun-2013 Jul-2011 Dec-2007 Mon-20XX Mon-20XX

13

Effexor

Venlafaxine

3,722

Dec-1993

Dec-2007

14

Protonix, Pantozol, Pantoloc Singulair Seroquel Prevacid, Takepron Procrit, Eprex

Pantoprazole

3,621

4% Wyeth, Altana, Solvay

Feb-2000

Mon-20XX

15 16 17

Montelukast Quetiapine Lansoprazole

3,579 3,560 3,425

20% Merck & Co. 23% AstraZeneca 3% TAP Pharmaceuticals, Takeda Pharmaceutical -4% Johnson & Johnson 4% Merck & Co. -2% Merck & Co. 83% Roche, Genentech, Chugai Pharmaceutical 14% Sanofi-Aventis

Asthma Schizophrenia Gastrointestinal disorders Anemia Hypertension Osteoporosis Breast cancer

Feb-1998 Sep-1997 May-1995

Feb-2012 Sep-2011 May-2009

18 19 20 21

Erythropoietin

3,180 3,163 3,134 3,134

Dec-1990 Apr-1995 Sep-1995 Sep-1998

Mon-20XX Mon-20XX Mon-20XX Mon-20XX

Cozaar, Hyzaar Losartan Fosamax Herceptin Alendronate Trastuzumab

22

Lovenox, Clexane Avandia, Avandamet, Avandaryl

Enoxaparin

3,059

Deep-vein thrombosis Type 2 diabetes

Mar-1993

Dec-2004

23

Rosiglitazone

3,043

26% GlaxoSmithKline

May-1999

Sep-2011

List of bestselling drugs

2
Pioglitazone 2,880 25% Takeda Pharmaceutical, Type 2 diabetes Eli Lilly and Company -36% Merck & Co. 19% Teva Pharmaceutical Industries, Sanofi-Aventis -4% Eisai, Johnson & Johnson 18% Amgen 16% Forest Laboratories, H. Lundbeck 18% Novartis Cholesterol Multiple sclerosis Jul-1999 May-2007

24

Actos

25 26

Zocor Copaxone

Simvastatin Glatiramer

2,803 2,757

Dec-1991 Dec-1996

Dec-2005 Mon-20XX

27

AcipHex, Pariet Neulasta Lexapro, Cipralex Gleevec, Glivec Ambien, Stilnox Aricept Epogen Zyrtec, Cirrus

Rabeprazole

2,729

Gastrointestinal disorders Neutropenia Depression, Anxiety disorders Leukemia

Aug-1999

May-2013

28 29

Filgrastim Escitalopram

2,710 2,696

Jan-2002 Aug-2002

Mon-20XX Sep-2011

30

Imatinib

2,554

May-2001

Jan-2015

31

Zolpidem

2,545

33% Sanofi-Aventis

Insomnia

Dec-1992

Oct-2006

32 33 34

Donepezil Erythropoietin Cetirizine

2,519 2,511 2,377

24% Pfizer 2% Amgen 9% Pfizer, UCB, Daiichi Sankyo 13% Sanofi-Aventis, Bristol-Myers Squibb

Alzheimers disease Anemia Allergic rhinitis

Nov-1996 Jun-1989 Dec-1995

Nov-2010 Mon-20XX Jun-2007

35

Avapro, Aprovel, Avalide Avastin Taxotere Eloxatin, Eloxatine Zoloft

Irbesartan

2,372

Hypertension

Sep-1997

Sep-2011

36 37 38

Bevacizumab Docetaxel Oxaliplatin

2,364 2,201 2,127

78% Roche, Genentech 9% Sanofi-Aventis 8% Sanofi-Aventis

Colorectal cancer Cancer Colorectal cancer

Feb-2004 Oct-1995 Aug-2002

Mon-20XX May-2010 Aug-2016

39

Sertraline

2,110

-35% Pfizer

Depression, Anxiety disorders Influenza

Dec-1991

Dec-2005

40

Tamiflu

Oseltamivir

2,096

69% Roche, Chugai Pharmaceutical, Hetero Drugs 37% Sanofi-Aventis

Oct-1999

Mon-20XX

41

Lantus

Insulin analog

2,093

Type 2 diabetes and type 1 diabetes Cholesterol Rheumatoid arthritis Osteoarthritis and rheumatoid arthritis Seizures Pneumococcal disease Cholesterol

Apr-2000

Dec-2011

42 43 44

Crestor Humira Celebrex

Rosuvastatin Adalimumab Celecoxib

2,049 2,044 2,039

61% AstraZeneca, Shionogi 46% Abbott Laboratories 18% Pfizer

Nov-2002 Dec-2002 Dec-1998

Jan-2016 Dec-2016 Mon-20XX

45 46

Topamax Prevnar

Topiramate vaccine

2,027 1,961

21% Johnson & Johnson 30% Wyeth

Dec-1996 Feb-2000

Sep-2008 Jan-2007

47

Vytorin

Ezetimibe + Simvastatin Ezetimibe

1,955

90% Merck & Co., Schering-Plough 38% Merck & Co., Schering-Plough

Jul-2004

Mon-20XX

48

Zetia

1,929

Cholesterol

Oct-2002

Oct-2016

List of bestselling drugs

3
Bupropion 1,926 26% GlaxoSmithKline, Biovail Depression, Seasonal affective disorder (SAD) Psychosis, Depression Seizures Hypertension Aug-2003 May-1994

49

Wellbutrin

50

Abilify

Aripiprazole

1,900

1% Otsuka Pharmaceutical, Bristol-Myers Squibb 19% GlaxoSmithKline 3% AstraZeneca

Nov-2002

Oct-2014

51 52

Lamictal Toprol, Seloken NeoRecormon, Epogin Atacand, Blopress Spiriva

Lamotrigine Metoprolol

1,843 1,795

Dec-1994 Jan-1992

Jul-2008 Mon-20XX

53

Erythropoietin

1,777

-1% Roche, Chugai Pharmaceutical

Anemia

Jul-1997

Mon-20XX

54

Candesartan

1,768

8% Takeda Pharmaceutical, Hypertension AstraZeneca 45% Boehringer Ingelheim Chronic obstructive pulmonary disease Multiple sclerosis

Oct-1997

Jul-2012

55

Tiotropium

1,735

Apr-2002

Jan-2018

56

Avonex

Interferon beta-1a Sildenafil Telmisartan

1,707

11% Biogen Idec

May-1996

Mon-20XX

57 58

Viagra Micardis

1,657 1,645

1% Pfizer 35% Boehringer Ingelheim, Astellas Pharma -4% Procter & Gamble, Sanofi-Aventis

Erectile dysfunction Hypertension

Mar-1998 Nov-1998

Mar-2012 Mon-20XX

59

Actonel

Risedronate

1,619

Osteoporosis

Mar-1998

Mon-20XX

60

Lupron, Leuplin TriCor, Lipanthyl Zofran

Leuprolide

1,579

1% Takeda Pharmaceutical, Prostate cancer TAP Pharmaceuticals 38% Abbott Laboratories, Solvay 3% GlaxoSmithKline Cholesterol

Jan-1989

Jan-1996

61

Fenofibrate

1,567

Feb-1998

Mon-20XX

62

Ondansetron

1,567

Nausea and vomiting Herpes Bacterial infections

Dec-1992

Jan-2005

63 64

Valtrex Levaquin, Floxin Arimidex Prograf CellCept

Valaciclovir Levofloxacin

1,563 1,530

24% GlaxoSmithKline 3% Johnson & Johnson

Jun-1995 Dec-1996

Jun-2009 Dec-2010

65 66 67

Anastrozole Tacrolimus Mycophenolate mofetil Latanoprost

1,508 1,499 1,470

28% AstraZeneca 20% Astellas Pharma 8% Roche, Chugai Pharmaceutical 6% Pfizer

Breast cancer Transplant rejection Transplant rejection

Dec-1995 Apr-1993 May-1995

Dec-2009 Apr-2008 May-2009

68

Xalatan, Xalacom Rebif

1,453

Intraocular pressure

Jun-1996

Jul-2006

69

Interferon beta-1a Carvedilol Gemcitabine

1,452

14% Serono

Multiple sclerosis

Feb-1998

Mon-20XX

70 71 72

Coreg Gemzar

1,441 1,408 1,371

38% GlaxoSmithKline 5% Eli Lilly and Company -17% AstraZeneca

Hypertension Cancer Gastrointestinal disorders Hypertension

Sep-1995 May-1996 Sep-1989

Mar-2007 May-2010 Apr-2001

Prilosec, Losec Omeprazole

73

Benicar, Olmetec Lotrel

Olmesartan

1,370

73% Daiichi Sankyo, Forest Laboratories 26% Novartis

Apr-2002

Apr-2016

74

Amlodipine + Benazepril

1,352

Hypertension

Jun-1999

Mon-20XX

List of bestselling drugs

4
Duloxetine 1,316 94% Eli Lilly and Company Depression, Anxiety disorders Migraine Aug-2004 Jun-2013

75

Cymbalta

76

Imitrex, Imigran Depakote

Sumatriptan

1,315

4% GlaxoSmithKline

Dec-1992

Dec-2006

77

Valproate semisodium Insulin analog Fentanyl Budesonide Zoledronate Interferon beta-1b Ramipril Fluticasone

1,308

19% Abbott Laboratories

Seizures

Mar-1983

Mon-20XX

78 79 80 81 82

Humalog Duragesic Pulmicort Zometa Betaseron, Betaferon Delix, Tritace Flovent, Flixotide Neupogen Casodex Pravachol Truvada

1,300 1,295 1,292 1,283 1,245

8% Eli Lilly and Company -18% Johnson & Johnson 11% AstraZeneca 5% Novartis 14% Schering AG

Diabetes Pain Asthma Hypercalcemia Multiple sclerosis

Apr-1996 Aug-1990 Jun-1997 Aug-2000 Jul-1993

Mon-20XX Mon-20XX Mon-20XX Mon-20XX Mon-20XX

83 84

1,227 1,219

-3% Sanofi-Aventis 5% GlaxoSmithKline

Hypertension Asthma

Jul-2000 Mar-1996

Mon-20XX Mon-20XX

85 86 87 88

Filgrastim Bicalutamide Pravastatin Tenofovir + Emtricitabine Budesonide + Formoterol Pegylated interferon alfa-2a Raloxifene

1,213 1,206 1,197 1,194

0% Amgen 7% AstraZeneca -47% Bristol-Myers Squibb 110% Gilead Sciences

Neutropenia Prostate cancer Cholesterol HIV infection

Feb-1991 Oct-1995 Oct-1991 Aug-2004

Mon-20XX Mon-20XX Mon-20XX Mon-20XX

89

Symbicort

1,184

18% AstraZeneca

Asthma

Aug-2000

Mon-20XX

90

Pegasys

1,171

5% Roche, Chugai Pharmaceutical 4% Eli Lilly and Company, Chugai Pharmaceutical 28% Boehringer Ingelheim

Hepatitis C

Jun-2002

Mon-20XX

91

Evista

1,159

Osteoporosis

Dec-1997

Mon-20XX

92

Flomax

Tamsulosin

1,158

Benign prostatic hypertrophy Neuropathic pain Depression, Anxiety disorders HIV infection Overactive bladder Benign prostatic hypertrophy Colorectal cancer

Oct-1997

Mon-20XX

93 94

Lyrica Paxil, Seroxat

Pregabalin Paroxetine

1,156 1,147

297% Pfizer 3% GlaxoSmithKline

Jul-2004 Dec-1992

Mon-20XX Mon-20XX

95 96 97

Kaletra Detrol Harnal

Lopinavir Tolterodine Tamsulosin

1,135 1,100 1,085

13% Abbott Laboratories 11% Pfizer -8% Astellas Pharma

Mar-2001 Mar-1998 Jul-1992

Mon-20XX Mon-20XX Mon-20XX

98

Erbitux

Cetuximab

1,075

56% Bristol-Myers Squibb, Merck KGaA -9% MedImmune

Feb-2004

Mon-20XX

99

Synagis

Palivizumab

1,065

Respiratory syncytial virus Bacterial infections Menopausal symptoms

Jun-1998

Mon-20XX

100 101

Augmentin Premarin, Prempro, Premphase Ortho contraceptives

Co-amoxiclav Estrogen

1,055 1,051

-13% GlaxoSmithKline 16% Wyeth

Aug-1984 Nov-1995

Mon-20XX Mon-20XX

102

Estrogen + Progesterone

1,016

-11% Johnson & Johnson

Contraception

Apr-1984

Mon-20XX

List of bestselling drugs

5
Goserelin Imiglucerase Levofloxacin 1,008 1,007 1,002 0% AstraZeneca 8% Genzyme 2% Daiichi Sankyo, Santen Pharmaceutical 36% Schering AG Prostate cancer Gaucher disease Bacterial infections Dec-1989 Apr-1991 Jun-1993 Mon-20XX Mon-20XX Mon-20XX

103 104 105

Zoladex Cerezyme Cravit

106

Yasmin

Drospirenone

998

Prevention of pregnancy Hemophilia

Aug-2000

Mon-20XX

107

Kogenate

Recombinant factor VIII Botulin toxin Terbinafine Lamivudine + Zidovudine

989

19% Bayer

Feb-1993

Mon-20XX

108 109 110

Botox Lamisil Combivir

982 978 977

18% Allergan -14% Novartis -8% GlaxoSmithKline

Cervical dystonia Fungal infections HIV infection

Dec-1989 Dec-1992 Sep-1997

Mon-20XX Mon-20XX Mon-20XX

111 112

Zosyn, Tazocin Piperacillin Cialis Tadalafil

972 971

9% Wyeth 30% Eli Lilly and Company, Lilly Icos 36% UCB 11% Novo Nordisk

Bacterial infections Erectile dysfunction

Oct-1993 Nov-2002

Mon-20XX Mon-20XX

113 114

Keppra NovoSeven

Levetiracetam Factor VII

956 948

Seizures Bleeding due to hemophilia Diphtheria, tetanus, and pertussis Allergic rhinitis HIV infection Attention-deficit hyperactivity disorder Diabetes

Nov-1999 Feb-1996

Mon-20XX Mon-20XX

115

Infanrix, Pediarix Nasonex Reyataz Concerta

vaccine

945

21% GlaxoSmithKline

Jan-1996

Mon-20XX

116 117 118

Mometasone Atazanavir Methylphenidate

944 931 930

28% Schering-Plough 34% Bristol-Myers Squibb 20% Johnson & Johnson

Oct-1997 Jan-2003 Aug-2000

Mon-20XX Mon-20XX Mon-20XX

119

Humulin

Recombinant human insulin Ciclosporin

925

-8% Eli Lilly and Company

Oct-1982

Mon-20XX

120

Neoral, Sandimmun Sandostatin Camptosar Engerix-B, Havrix, Twinrix

918

-4% Novartis

Transplant rejection

Jul-1995

Mon-20XX

121 122 123

Somatostatin Irinotecan vaccine

915 903 886

2% Novartis -1% Pfizer 10% GlaxoSmithKline

Acromegaly Colorectal cancer Hepatitis

Oct-1988 Jun-1996 Aug-1989

Mon-20XX Mon-20XX Mon-20XX

124 125

Allegra, Telfast Fexofenadine Adderall Amphetamine

864 864

-49% Sanofi-Aventis 18% Shire Pharmaceuticals

Allergic rhinitis Attention-deficit hyperactivity disorder Chronic obstructive pulmonary disease Hepatitis C

Jul-1996 Oct-2001

Mon-20XX Mon-20XX

126

Combivent

Ipratropium + Salbutamol Pegylated interferon alfa-2b Nifedipine Moxifloxacin

843

20% Boehringer Ingelheim

Oct-1996

Mon-20XX

127

Peg-Intron

837

11% Schering-Plough

May-2000

Mon-20XX

128 129

Adalat Avelox, Avalox

825 822

0% Bayer 17% Bayer, Schering-Plough, Shionogi

Hypertension Bacterial infections

Nov-1985 Dec-1999

Mon-20XX Mon-20XX

List of bestselling drugs

6
Meloxicam 818 -66% Boehringer Ingelheim, Daiichi Sankyo -23% Abbott Laboratories -35% Daiichi Sankyo -9% Abbott Laboratories Osteoarthritis and rheumatoid arthritis Bacterial infections Cholesterol Anesthesia Feb-1996 Mon-20XX

130

Mobic

131 132 133

Biaxin Mevalotin Ultane, Sevorane Genotropin Sustiva Zyvox Xeloda

Clarithromycin Pravastatin Sevoflurane

816 799 799

Oct-1991 Jun-1909 Jun-1995

Mon-20XX Mon-20XX Mon-20XX

134 135 136 137

Somatropin Efavirenz Linezolid Capecitabine

795 791 782 775

-2% Pfizer 16% Bristol-Myers Squibb 27% Pfizer 22% Roche, Chugai Pharmaceutical 29% Pfizer

Growth failure HIV infection Bacterial infections Cancer

Aug-1995 Sep-1998 Apr-2000 Jun-1909

Mon-20XX Mon-20XX Mon-20XX Mon-20XX

138

Geodon, Zeldox Cipro, Ciprobay Provigil Lescol Clarinex, Aerius Femara

Ziprasidone

758

Schizophrenia

Feb-2001

Mon-20XX

139

Ciprofloxacin

755

-6% Bayer, Schering-Plough Bacterial infections

Oct-1987

Mon-20XX

140 141 142

Modafinil Fluvastatin Desloratadine

735 725 722

43% Cephalon -5% Novartis 12% Schering-Plough

Sleepiness Cholesterol Allergic rhinitis

Dec-1998 Dec-1993 Dec-2001

Mon-20XX Mon-20XX Mon-20XX

143

Letrozole

722

35% Novartis, Chugai Pharmaceutical 17% Novartis 42% Actelion

Breast cancer

Jul-1997

Mon-20XX

144 145

Trileptal Tracleer

Oxcarbazepine Bosentan

721 717

Seizures Pulmonary arterial hypertension Bacterial infections

Nov-1999 Nov-2001

Mon-20XX Mon-20XX

146

Primaxin

Imipenem + Cilastatin Temozolomide

705

-5% Merck & Co.

Nov-1985

Mon-20XX

147

Temodar

703

20% Schering-Plough

Anaplastic astrocytoma Intraocular pressure

Aug-1999

Mon-20XX

148

Trusopt, Cosopt Voltaren

Dorzolamide

697

13% Merck & Co.

Dec-1994

Mon-20XX

149

Diclofenac

690

0% Novartis

Osteoarthritis and rheumatoid arthritis HIV infection Parkinsons disease Alzheimer disease Cardiovascular events Type 2 diabetes

Jul-1998

Mon-20XX

150 151 152 153

Viread Sifrol Namenda Altace

Tenofovir Pramipexole Memantine Ramipril

689 673 660 653

-12% Gilead Sciences 23% Boehringer Ingelheim 30% Forest Laboratories 18% King Pharmaceuticals

Oct-2001 Oct-1997 Oct-2003 Jan-1991

Mon-20XX Mon-20XX Mon-20XX Mon-20XX

154

Byetta

Exenatide

649

464% Amylin Pharmaceuticals, Eli Lilly and Company 110% Roche, Genentech

Apr-2005

Mon-20XX

155

Tarceva

Erlotinib

649

Non-small cell lung cancer Bacterial infections

Nov-2004

Mon-20XX

156

Zithromax, Zmax Omnicef

Azithromycin

638

-68% Pfizer

Nov-1991

Mon-20XX

157

Cefdinir

637

29% Abbott Laboratories

Bacterial infections

Dec-1997

Mon-20XX

List of bestselling drugs

7
Finasteride 619 -16% Merck & Co. Benign prostatic hypertrophy Non-small cell lung cancer Bacterial infections Osteoporosis Attention-deficit hyperactivity disorder Cancer pain Allergic rhinitis Jun-1992 Mon-20XX

158

Proscar

159

Alimta

Pemetrexed

612

32% Eli Lilly and Company

Feb-2004

Mon-20XX

160 161 162

Merrem Forteo Strattera

Meropenem Teriparatide Atomoxetine

604 594 579

20% AstraZeneca 53% Eli Lilly and Company 5% Eli Lilly and Company

Jun-1996 Nov-2002 Nov-2002

Mon-20XX Mon-20XX Mon-20XX

163 164

Actiq Flonase, Flixonase Amaryl Lidoderm Lunesta Boniva, Bonviva Taxol Zelnorm, Zelmac Renagel

Fentanyl Fluticasone

578 575

40% Cephalon -52% GlaxoSmithKline

Nov-1998 Oct-1994

Mon-20XX Mon-20XX

165 166 167 168

Glimepiride Lidocaine Eszopiclone Ibandronate

567 567 567 565

-33% Sanofi-Aventis 35% Endo Pharmaceuticals 72% Sepracor 454% Roche, GlaxoSmithKline -25% Bristol-Myers Squibb 34% Novartis

Type 2 diabetes Pain Insomnia Osteoporosis

Nov-1995 Mar-1999 Dec-2004 Mar-2005

Mon-20XX Mon-20XX Mon-20XX Mon-20XX

169 170

Paclitaxel Tegaserod

563 561

Cancer Irritable bowel syndrome Hyperphosphatemia

Dec-1992 Mar-2002

Mon-20XX Mon-20XX

171

Sevelamer

559

23% Genzyme, Roche, Chugai Pharmaceutical 19% Novo Nordisk

Oct-1998

Mon-20XX

172

Norditropin

Human growth hormone Levalbuterol Orlistat Enalapril

557

Growth hormone deficiency Bronchospasm Obesity Hypertension

Jun-1909

Mon-20XX

173 174 175

Xopenex Xenical Vasotec, Vaseretic Serevent Cardura Synthroid Gonal-f Pepcid, Gaster

555 553 547

29% Sepracor 9% Roche -12% Merck & Co.

Mar-1999 Jul-1998 Dec-1985

Mon-20XX Mon-20XX Mon-20XX

176 177 178 179 180

Salmeterol Doxazosin Levothyroxine Follitropin alfa Famotidine

538 538 534 533 532

-10% GlaxoSmithKline -8% Pfizer -4% Abbott Laboratories -3% Serono -10% Astellas Pharma

Asthma Hypertension Hypothyroidism Infertility Gastrointestinal disorders Fungal infections Alzheimers disease Fungal infections Hypertension, angina pectoris Cholesterol Seizures HIV infection

Feb-1994 Nov-1990 May-1909 Oct-1995 Jun-1909

Mon-20XX Mon-20XX Mon-20XX Mon-20XX Mon-20XX

181 182 183 184

Cancidas Exelon Vfend Amlodin

Caspofungin Rivastigmine Voriconazole Amlodipine

530 525 515 506

-7% Merck & Co. 12% Novartis 30% Pfizer 4% Dainippon Sumitomo

Jan-2001 May-1998 Mar-2002 n/a

Mon-20XX Mon-20XX Mon-20XX Mon-20XX

185 186 187

Niaspan Neurontin Trizivir

Niacin Gabapentin Abacavir + Lamivudine + Zidovudine

498 496 496

13% Kos Pharmaceuticals -22% Pfizer -10% GlaxoSmithKline

Jul-1997 Dec-1993 Nov-2000

Mon-20XX Mon-20XX Mon-20XX

List of bestselling drugs

8
Ropinirole Follitropin beta 496 482 74% GlaxoSmithKline 8% Akzo Nobel Parkinson disease Infertility Sep-1997 Sep-1997 Mon-20XX Mon-20XX

188 189

Requip Follistim, Puregon Basen Levitra

190 191

Voglibose Vardenafil

476 474

-13% Takeda Pharmaceutical 19% Bayer, GlaxoSmithKline -16% Merck KGaA, Bristol-Myers Squibb 4% Merck KGaA 107% GlaxoSmithKline

Hyperglycemia Erectile dysfunction

Jun-1909 Mar-2003

Mon-20XX Mon-20XX

192

Glucophage

Metformin

459

Type 2 diabetes

Dec-1994

Mon-20XX

193 194

Concor Epzicom, Kixeva Xatral

Bisoprolol Abacavir + Lamivudine Alfuzosin

455 446

Hypertension HIV infection

Jul-1992 Aug-2004

Mon-20XX Mon-20XX

195

443

8% Sanofi-Aventis

Benign prostatic hypertrophy Fungal infections Erythema nodosum leprosum Gastrointestinal disorders Asthma Allergic rhinitis

Jan-2000

Mon-20XX

196 197

Diflucan Thalomid

Fluconazole Thalidomide

435 433

-13% Pfizer 12% Celgene

Jan-1990 Jul-1998

Mon-20XX Mon-20XX

198

Zantac

Ranitidine

429

-18% GlaxoSmithKline

Jun-1983

Mon-20XX

199 200

Xolair Claritin

Omalizumab Loratadine

429 418

32% Roche, Genentech -5% Schering-Plough, Shionogi & Co.

Jun-2003 Apr-1993

Mon-20XX Mon-20XX

Source: MedAdNews 200 - World's Best-Selling Medicines, MedAdNews, July 2007

References
[1] Patent Terms Extended Under 35 USC 156 (http:/ / www. uspto. gov/ patents/ resources/ terms/ 156. jsp) [2] Orange Book Trade Name Search (http:/ / www. accessdata. fda. gov/ scripts/ cder/ ob/ docs/ querytn. cfm)

Article Sources and Contributors

Article Sources and Contributors

List of bestselling drugs Source: http://en.wikipedia.org/w/index.php?oldid=432214079 Contributors: Aseld, Bmmayhew, C6541, CliffC, Colin, Coolhandscot, David A. Victor, Dikteren, Douglasjoseph, Edgar181, Enix150, Fvasconcellos, GJeffery, Ivansanchez, Jmh649, Lycaon83, Mbenzdabest, Mgreason, Msanjelpie, Muad, Newcastleunii, Nono64, Paul A, R'n'B, RXPhd, Shilpam13, WikHead, Willking1979, 16 anonymous edits

License
Creative Commons Attribution-Share Alike 3.0 Unported http:/ / creativecommons. org/ licenses/ by-sa/ 3. 0/