Xanthan Gum MSDS
Xanthan Gum MSDS
Xanthan Gum MSDS
Product Identifier
Product name GUM XANTHAN
Chemical Name gum xanthan
xanthan gum; polysaccharide gum; xanthum; xanthem; xanthen; xanthum gum; Kelco Kelzan AR; Kelco Xanvis; Keltrol F, M, T, TF, BT, GM, RD,
SF, 1000, PF300, K1B111; Kelco D, D35, M, MU, S, XC, XCD; Flocon 1035; Keltrol T; Rhodopol 23; Kelzan S; Xanvis; Actigum CX 9; Biozan R;
Keltrol TF 1000; Kelzan XC; Monategum GS; Ekogum ketorol; Kelzan XCD; Kelzan AR; biopolymer 9702; xanthan Gum(food grade); xanthan
Synonyms gum NF, EP, JP; xanthan; Rhodopol R 23; xanthan gum food grade 80MESH; xanthan gum pharmaceutical grade 80MESH; xanthan gun;
xanthan gum(food grade,oil drilling grade,etc); xanthan Gum,11138-66-2; Capryl mono glyceride(CMG); Xanthan Gum FCC4; San Ace; Echogum
F; Echogum T; Rhodoflood XR 75; Keltrol RD; XC 85II-F4; Xanflood; Idvis; XB 23; Kelzan F; Kelzan MF; Kelzan M; Keltrol TF; Kelzan T; Shellflo
XA; Satiaxane CX
Chemical formula Not Available
Other means of identification Not Available
CAS number 11138-66-2
Relevant identified uses of the substance or mixture and uses advised against
In foods, non-foods, and cosmetics as stabilizer and emulsifying agent.Used in chemically enhanced oil recovery.
Polysaccharides obtained from bacteria or fungal sources, may accumulate inside the cells displaying storage function such as glycogen, may be
present as structural components in the form of a slime layer as capsular polysaccharides or secreted outside the cells as extracellular bacterial
polysaccharides or exopolysaccharides (EPS) e.g. xanthan, bacterial alginate, sphingan etc. Structurally related exopolysaccharides may or
Relevant identified uses
may not demonstrate a similar aqueous solubility profile, rheological behavior, thermostability and acid stability. Gel-forming polysaccharides
have been found to be mostly water-insoluble producing thermostable gels. Non-gel forming polysaccharides may be water-soluble or water-
insoluble. A common structural feature found in all non-gel forming exopolysaccharides is the presence of protective side chains preventing
favourable interactions between solvent molecules and highly active functional groups like carboxylate groups.
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NON-HAZARDOUS CHEMICAL. NON-DANGEROUS GOODS. According to the WHS Regulations and the ADG Code.
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Label elements
Hazard statement(s)
Not Applicable
Substances
CAS No %[weight] Name
11138-66-2 >99 gum xanthan
Legend: 1. Classified by Chemwatch; 2. Classification drawn from HCIS; 3. Classification drawn from Regulation (EU) No 1272/2008 - Annex VI; 4. Classification drawn from C&L;
* EU IOELVs available
Mixtures
See section above for composition of Substances
Extinguishing media
Water spray or fog.
Foam.
Dry chemical powder.
BCF (where regulations permit).
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form flammable dust clouds; once initiated, however, larger particles up to 1400 microns diameter will contribute to the propagation of an
explosion.
Combustion products include:
carbon monoxide (CO)
carbon dioxide (CO2)
other pyrolysis products typical of burning organic material.
HAZCHEM Not Applicable
Environmental precautions
See section 12
Control parameters
Exposure controls
Engineering controls are used to remove a hazard or place a barrier between the worker and the hazard. Well-designed engineering controls can
be highly effective in protecting workers and will typically be independent of worker interactions to provide this high level of protection.
Appropriate engineering The basic types of engineering controls are:
controls Process controls which involve changing the way a job activity or process is done to reduce the risk.
Enclosure and/or isolation of emission source which keeps a selected hazard "physically" away from the worker and ventilation that strategically
"adds" and "removes" air in the work environment.
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Personal protection
Respiratory protection
Particulate. (AS/NZS 1716 & 1715, EN 143:2000 & 149:001, ANSI Z88 or national equivalent)
Required Minimum Protection Factor Half-Face Respirator Full-Face Respirator Powered Air Respirator
P1 - PAPR-P1
up to 10 x ES
Air-line* - -
up to 50 x ES Air-line** P2 PAPR-P2
up to 100 x ES - P3 -
Air-line* -
100+ x ES - Air-line** PAPR-P3
· Respirators may be necessary when engineering and administrative controls do not adequately prevent exposures.
· The decision to use respiratory protection should be based on professional judgment that takes into account toxicity information, exposure measurement data, and frequency
and likelihood of the worker's exposure - ensure users are not subject to high thermal loads which may result in heat stress or distress due to personal protective equipment (powered,
positive flow, full face apparatus may be an option).
· Published occupational exposure limits, where they exist, will assist in determining the adequacy of the selected respiratory protection. These may be government mandated or
vendor recommended.
· Certified respirators will be useful for protecting workers from inhalation of particulates when properly selected and fit tested as part of a complete respiratory protection
program.
· Where protection from nuisance levels of dusts are desired, use type N95 (US) or type P1 (EN143) dust masks. Use respirators and components tested and approved under
appropriate government standards such as NIOSH (US) or CEN (EU)
· Use approved positive flow mask if significant quantities of dust becomes airborne.
· Try to avoid creating dust conditions.
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The material has NOT been classified by EC Directives or other classification systems as "harmful by ingestion". This is because of the lack of
corroborating animal or human evidence.
Ingestion Polysaccharides are not easily absorbed from the digestive tract, but may produce a laxative effect. Larger doses may produce intestinal or
stomach blockage.
<
The material is not thought to produce adverse health effects or skin irritation following contact (as classified by EC Directives using animal
Skin Contact models). Nevertheless, good hygiene practice requires that exposure be kept to a minimum and that suitable gloves be used in an occupational
setting.
Although the material is not thought to be an irritant (as classified by EC Directives), direct contact with the eye may cause transient discomfort
Eye
characterised by tearing or conjunctival redness (as with windburn). Slight abrasive damage may also result.
Long-term exposure to the product is not thought to produce chronic effects adverse to the health (as classified by EC Directives using animal
models); nevertheless exposure by all routes should be minimised as a matter of course.
Long term exposure to high dust concentrations may cause changes in lung function i.e. pneumoconiosis, caused by particles less than 0.5
Chronic
micron penetrating and remaining in the lung.
Studies indicate that diets containing large amounts of non-absorbable polysaccharides, such as cellulose, might decrease absorption of calcium,
magnesium, zinc and phosphorus.
TOXICITY IRRITATION
gum xanthan
Not Available Not Available
Legend: 1. Value obtained from Europe ECHA Registered Substances - Acute toxicity 2.* Value obtained from manufacturer's SDS. Unless otherwise
specified data extracted from RTECS - Register of Toxic Effect of chemical Substances
Evaluation of workers exposed to xanthan gum dust found evidence of a link to respiratory symptoms.. On May 20, 2011, the FDA issued a press
release about SimplyThick, a food-thickening additive containing xanthan gum as the active ingredient, warning parents, caregivers and health
care providers not to feed SimplyThick, a thickening product, to premature infants[. The concern is that the product may cause premature infants
to suffer necrotizing enterocolitis. According to a 2017 safety review by a scientific panel of the European Food Safety Authority (EFSA), xanthan
gum (European food additive number E 415) is extensively digested during intestinal fermentation, and causes no adverse effects, even at high
intake amounts. The EFSA panel found no concern about genotoxicity from long-term consumption. EFSA concluded that there is no safety
concern for the general population when xanthan gum is consumed as a food additive. Xanthan gum (E 415) can be regarded as non-toxic based
on the results of acute oral toxicity studies.From short-term and subchronic toxicity studies, no toxicological relevant changes were reported apart
GUM XANTHAN
from a decrease in red blood cell count and haemoglobin concentration in dogs receiving 2,000 mg/kg body weight (bw) per day for 12 weeks.
This effect was marginal and it was not reproduced in a dog chronic toxicity study at 1,000 mg/kg bw per day, the highest dose tested. The EFSA
Panel noted that decreased total serum cholesterol was frequently reported.For genotoxicity, insufficient experimental data were available.
However, taking into account the information on structure–activity relationships and considering that xanthan gum has a molecular w eight far
above the threshold for absorption, according to absorption, distribution, metabolism, and excretion (ADME) data, it was not degraded in the
intestine and is slightly fermented to non-hazardous short-chain fatty acids by the gut microbiota, the Panel concluded that xanthan gum (E 415)
does not give rise to concerns for genotoxicity.In chronic and long-term studies, no adverse effects, including biochemical and haematological
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parameters, were reported in dogs and rats. From a human study with repeated intake ranging from 10.4 to 12.9 g of xanthan gum per
day(assuming a body weight of 70 kg corresponding to 149–184 mg/kg bw per day), it was reported that xanthan gum acts as a bulk laxative
causing no adverse dietary nor physiological effects. The only effects observed were moderate (10%) reduction in serum cholesterol (p<0.05)
and a significant increase in faecal bile acid concentrations (p<0.05) .A study investigating the effect of repeated intake of 15 g xanthan gum/day
(assuming a bodyweight of 70 kg corresponding to 214 mg/kg bw per day) on colonic function showed significant increases in stool output
(p<0.01), frequency of defecation (p<0.05) and flatulence (p<0.01) due to the ingestion of the xanthan gum.In clinical studies involving infants,
the Panel noted that consumption of xanthan gum in infant formula or formula for special medical purposes in infant was well tolerated, did not
influence minerals(Ca, P, Mg), fat and nitrogen balance and did not affect growth characteristics up to concentration of 1,500 mg/L (232 mg/kg bw
per day). These results were supported by the outcome of the post-marketing surveillance with formulae containing xanthan gum at a
concentration of approximately 750 mg/L of reconstituted formula. No significant acute toxicological data identified in literature search.
Toxicity
Legend: Extracted from 1. IUCLID Toxicity Data 2. Europe ECHA Registered Substances - Ecotoxicological Information - Aquatic Toxicity 3. EPIWIN Suite
V3.12 (QSAR) - Aquatic Toxicity Data (Estimated) 4. US EPA, Ecotox database - Aquatic Toxicity Data 5. ECETOC Aquatic Hazard Assessment
Data 6. NITE (Japan) - Bioconcentration Data 7. METI (Japan) - Bioconcentration Data 8. Vendor Data
Sugar-based compounds (saccharides), including polysaccharides are generally easily decomposed by biodegradation. Not all polysaccharides decompose with equal rapidity, and
polysaccharides are also synthesised by microorganisms during, for example, the compost maturation phases. Water-insoluble species such as cellulose take longer to decompose
and those with a significant degree of branching also take longer.
Bioaccumulative potential
Ingredient Bioaccumulation
No Data available for all ingredients
Mobility in soil
Ingredient Mobility
No Data available for all ingredients
Labels Required
Marine Pollutant NO
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Air transport (ICAO-IATA / DGR): NOT REGULATED FOR TRANSPORT OF DANGEROUS GOODS
Sea transport (IMDG-Code / GGVSee): NOT REGULATED FOR TRANSPORT OF DANGEROUS GOODS
Transport in bulk in accordance with MARPOL Annex V and the IMSBC Code
Product name Group
gum xanthan Not Available
Safety, health and environmental regulations / legislation specific for the substance or mixture
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Other information
Classification of the preparation and its individual components has drawn on official and authoritative sources as well as independent review by the Chemwatch Classification
committee using available literature references.
The SDS is a Hazard Communication tool and should be used to assist in the Risk Assessment. Many factors determine whether the reported Hazards are Risks in the workplace or
other settings. Risks may be determined by reference to Exposures Scenarios. Scale of use, frequency of use and current or available engineering controls must be considered.
end of SDS