Nicart, Jeric-Vincent C. - Genetics Laboratory

Activity on Gene Segregation and Integration
Name: NICART, JERIC-VINCENT C. Course: Genetics Lecture

Program: BSE 2-2 Science Score: ________________
I. Do the problem on Mendel’s Law using the Punnett Square.
1. In cats, long hair is recessive to short hair. A true-breeding (homozygous) short-haired male is
mated to a long-haired female. What will their kittens look like? (For uniformity: Long hair, LL, and
short hair, ll or small letter L).
P: LL x ll
L L
l Ll Ll
l Ll Ll
Phenotypic ratio: 4:0
2. A man with dark (dominant), curly hair marries a woman with light, straight hair. Their daughter, who
happens to have dark hair, marries a man with light, wavy hair. Answer the following questions about this
dark-haired daughter and her family. To Identify whether the hair of the daughter is Curly or Wavy, draw
first the Punnett Square of the Father and Mother.
D = Dark C1 = Curly
D = Light C2 = Wavy
a. Draw a Punnett’s square for this marriage, and predict the phenotypic ratio among the
offspring of the daughter and her husband.
Father – dark, curly

Mother – light, straight
Daughter – dark,?
Husband – light, wavy
D – dark
d – light
C – Curly
c – straight
P: DDCC x ddcc Husband F1: dd x C

F1: Dd x Cc dc, dc
F2: DC, Dc, dC, dc

DC Dc dC dc
dC DdCC DdCc ddCC ddCc
dc DdCc Ddcc ddCc ddcc
Phenotype:
Dark curly – 1 Light curly – 1

Dark wavy – 2 Light wavy - 2
Dark straight – 1 Light straight - 1
b. What is the chance that they will have a child with hair just like his or her father’s?
- 1/8 Chance or 12.5%
3. A man with type O blood marries a woman with Type AB blood. Among their children, what proportion
would you expect to have blood types like one or the other of these parents? What proportion would have
expected to have blood types different from both parents? Explain.
P: OO x AB
A B
O AO BO
O AO BO
A: 2:4 or 50%
B: 2:4 or 50%
Explanation:
When an AB blood type woman and an O blood type man have a child, the likely blood types for their
children will be either A or B. O or AB blood types are not possible in this scenario.
Human blood type is determined by three alleles: A, B, and O. Each individual inherits two alleles, one from
each parent, resulting in six possible genotype combinations: AA, BB, AO, BO, OO. Dominant A and B
alleles determine the phenotype, while the O allele is recessive.
The woman with AB blood type has a genotype of AB, while the man with O blood type has a genotype of
OO. Using a Punnett square, combining these genotypes results in a 50% chance of the child having A
blood type (AO) and a 50% chance of having B blood type (BO). The child cannot have O or AB blood type
based on this genetic combination.
4. In cats, there is a gene which produces ticked fur (bands of different colors on each hair) called Agouti
(H). The recessive allele (h) for this gene produces hair which is a solid color from end to end. In addition,
there is a coat color gene which has a recessive albino allele (a) which, in the homozygote, prevents the
production of any coat color pigment, resulting in a white cat with pink eyes, the traditional albino. Note that
this problem has described two completely different genes. These genes are unlinked. An albino female
cat is mated to a solid brown male cat. All of their offspring are Agouti. The males and females among
these offspring are allowed to freely intermate, producing a flock of F2 kittens. Predict the phenotypic ratio
for fur color among these many grandkittens. Assign B/b to the alleles for the Agouti/brown gene and A/a
to the alleles for the albino gene. (Bb = Agouti/brown; Aa = Albino).
Answer:
In this scenario, an albino female cat and a solid brown male cat have produced agouti kittens. The female
albino likely carries the agouti allele, possibly in duplicate, but it's uncertain. The male likely has two copies
of the normal albino allele, although this isn't confirmed.
All the agouti offspring inherited one albino allele from their mother and one normal allele from their father.
They're not albino due to the normal allele from their father, and they're agouti because of the agouti allele
inherited from their mother. This situation aligns with a classic dihybrid cross: BbAa x BbAa.
BA Ba bA ba
BA BBA BBAa BbAA BbAa
A
Ba BBAa BBaa BbAa Bbaa
bA BbAA BbAa bbAA bbAa
ba BbAa Bbaa bbAa bbaa
Agouti (BA): 9
Solid brown (Ba): 3
Albino (bb): 4

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Activity on Gene Segregation and Integration

Name: NICART, JERIC-VINCENT C. Course: Genetics Lecture

I. Do the problem on Mendel’s Law using the Punnett Square.

Phenotypic ratio: 4:0

Father – dark, curly

P: DDCC x ddcc Husband F1: dd x C

F2: DC, Dc, dC, dc

Dark curly – 1 Light curly – 1

- 1/8 Chance or 12.5%

ba BbAa Bbaa bbAa bbaa

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