Inference Based CBT Questions
Inference Based CBT Questions
Inference Based CBT Questions
Inference-based CBT (I-CBT) is a specialized cognitive-based treatment developed specifically for OCD.
Its goal is to target and resolve the faulty reasoning narratives and processes that lead to obsessional
doubts (aka obsessions). If the doubting was resolved, what would be left of OCD?
I-CBT is not a traditional CT. It does not utilize strategies to dispute or refute the content of one’s
obsessional doubting and it does not prioritize the challenging of post-doubting beliefs and
consequences. It targets the faulty reasoning processes that generate here-and-now obsessional
doubting. In this way, it is primarily a reasoning-focused cognitive therapy.
No. I-CBT is a reasoning-focused cognitive therapy. Deliberate, prolonged in vivo or imaginal exposures
are not a part of the treatment model and not relied upon. Its model is summarized as the knowing
precedes the doing. While there is a case-series published that indicates ERP can reduce inferential
confusion (obsessional doubting) it is not required.
The most obvious difference is that ERP is exposure therapy while I-CBT is a specialized cognitive
therapy focused on reasoning. However, when we look more closely at the underlying theories, the
differences become much larger. I-CBT views OCD as a doubting disorder as opposed to ERPs underlying
theory, which views OCD as an anxiety disorder or exaggerated phobic disorder. From an I-CBT lens,
anxiety and compulsions are all downstream byproducts of obsessional doubting and relevant to the
maintenance of OCD but not the central problem. No doubting means no anxiety and no compulsions.
This is also another significant departure from other models of OCD treatment. Historically, models
(CBT/ERP and ACT) have suggested that obsessions come about by unwanted thoughts that descriptively
intrude into awareness and are then negatively appraised (Thought-Action Fusion, and the 6 belief
domains). It is this interaction that determines which unwanted thoughts will become obsessions and
which will not. These unwanted thoughts are considered normal and not specific to those with OCD, so
they are not a target for treatment/resolution. Therefore, the endgame for how other models deal with
unwanted thoughts is that they must be accepted and tolerated because they are normal. This is why
they all focus on the emotional and compulsive reaction to the thoughts.
I-CBT, on the other hand, does not see obsessions coming about by negative beliefs about normal
unwanted thoughts. Instead, it argues that obsessions are actually the result of faulty reasoning
narratives that cause one to doubt a circumstance in the here-and-now where no doubt was needed.
This is referred to as an inference of doubt or a decision to doubt arrived at through a reasoning
process. This process is faulty, so the doubt is false. This is referred to as inferential confusion (IC).
Numerous peer-reviewed studies have demonstrated IC to be a more specific predictor of OCD than the
6 belief domains (intolerance for uncertainty, perfectionism, inflated responsibility, overestimation of
threat, over importance of thoughts, and excessive concern about controlling one’s thoughts) as well as
thought-Action fusion beliefs and IC is specific to OCD whereas the belief domains are not.
Inferential confusion is a confusion between reality and possibility during reasoning which gives undue
credibility to obsessional doubts. A number of reasoning processes that have been identified in the
model exemplify this confusion, which can broadly be categorized as an overreliance on possibility, or
the imagination, and a distrust of the senses and self during reasoning. Fundamentally, the error in
making what is irrelevant in the here-and-now seem relevant and real. There is a psychometrically
validated questionnaire, Inferential Confusion Questionnaire-EV (ICQ-EV) which measures one’s level of
IC. Reductions in the ICQ-EV scores are also correlated to the reduction in Y-BOCS scores.
In I-CBT, the doubt that begins the OCD sequence in the here-and-now is a verb, doubting. Uncertainty
is a downstream experience provoked by the doubting in the here-and-now. If one has not doubted,
then there would be no OCD themed uncertainty. Moreover, because OCD is activated in moments
rather than a 24/7 experience, there is a reality known through one’s 5-senses and common sense prior
to the doubting taking over. I-CBT aims to restore trust in one’s 5 senses and common sense that was
overshadowed by the doubting. In this way, I-CBT says there is certainty that one can reconnect with
and trust no different than those without OCD have about their present moments. Lastly, I-CBT does not
see future abstract possibilities as relevant to OCD. The doubting is activated now, trusted now, and
treated as if real, now. What is happening now is where the problem is. So, while it’s true to say, no one
has certainty about the future, it is also irrelevant if we have doubting happening now that goes against
the 5-senses reality and common sense of now.
I-CBT distinguishes normal doubting from obsessional doubting. Normal doubting arises when prompted
by relevant here-and-now reality. For instance, I see and smell smoke in my house and this leads me to
say what if there is a fire in my house or my doctor discovers a lump and wants to biopsy it, and this
leads me to say what if this lump is cancerous.
Obsessional doubt on the other hand arises from imagined or hypothetical prompts. For instance, upon
receiving my biopsy results where the document states my name, dob, lab tech, and my doctor’s name
along with the results reading benign, I say what if they switched my labs. This doubt was not arrived at
via relevant here-and-now reality. In fact, it was conjured and trusted despite it.
Is I-CBT evidence-based?
Yes. There are over 100 peer-reviewed articles published from different labs. These include theory,
experimental, cross-sectional, psychometric, and outcome trials. Specifically, open-trials, 3 RCTs, and 2
non-inferiority RCTs comparing I-CBT to ERP finishing in 2024. To date, research has only looked at adult
populations.
Recent meta-analyses (Reid, et al., 2021 and Öst, et al., 2015) and a patient-level mega-analysis
(Steketee, et al., 2019) found CBT/ERP to provide clinically significant change in Y-BOCS scores for 50%
of sufferer’s and treatment response for approximately 60% of sufferers. Open-trials and the 3 RCTs of I-
CBT have all shown similar outcome results where there were no statistically significant differences in
effect sizes between the two. This data prompted researchers to establish a non-inferiority RCT to
demonstrate true equivalence between ERP and I-CBT. To date there are two non-inferiority trials
underway. One in Canada and the other in the Netherlands. Preliminary data from the Canadian trial
shows non-inferiority to ERP.
If I-CBT is evidence-based, why is it not recommended under division 12 of the APA like CBT/ERP is?
Table 1. Rationale and mechanisms of change in each active treatment (I-CBT, A-CBT and Mindfulness).
Rationale
Inference‐based CBT Appraisal‐Based CBT Mindfulness (MBSR)
‐ Obsessions are faulty inferences of doubt about a possible ‐ Obsessions have their genesis in intrusive cognitions, which ‐ Obsessions are just like any other thought that do not
state of affairs of in reality (what “might be” or “could be”). are random thoughts without inherent meaning. reflect truth or reality or define who one is.
‐ Obsessions are the product of a dysfunctional reasoning ‐ Obsessions develop as the result of dysfunctional appraisals ‐ No specific rationale except that the obsessions are
narrative leading the person to confuse reality with and undue significance given to normal intrusive cognitions maintained by the inability to disengage from them.
imagination (i.e., “inferential confusion”) guided by specific obsessive beliefs.
‐ Dysfunctional reasoning processes that give rise to a state ‐ Obsessive appraisal and belief domains leading intrusions to ‐ The inability to decenter from obsessional thoughts
of inferential confusion characterized by an overreliance on develop into obsessions revolve around over‐responsibility, results in lack of cognitive flexibility and perspective
possibility and a distrust of the senses and/or self during overestimation of threat, over‐importance given to thoughts, taking that contribute to maladaptive self‐regulation
reasoning, including 1) inverse inference, 2) dismissal of control of thoughts, perfectionism and intolerance of processes and behaviours.
sense information 3) irrelevant associations uncertainty
‐ Vulnerable self‐themes and feared self‐perceptions ‐ A lack of (self‐) confidence in memory, decision making and ‐ Lack of awareness and attention regulatory skills may
underlie obsessional narratives information processing may underlie obsessions. underlie the cycle of obsessions.
‐ OCD primarily follows a non‐phobic model of development ‐ OCD primarily follows a phobic model development similar to ‐ No specific underlying model of development for OCD
similar to overvalued ideas or delusions through other anxiety disorders through the significance attached to except that lack of mindfulness perpetuates intolerance
dysfunctional reasoning and personal investment in intrusive cognitions and the reinforcing role of anxiety and of obsessions and reflexive patterns of reacting to them.
obsessional doubts that gives rise to unsuccessful avoidance behaviors (cognitive and overt avoidance,
neutralizing and avoidance behaviors. neutralization, safety‐seeking behaviors).
‐ Treatment is based on a constructionist model, where ‐ Treatment is based on a mediational realist model where ‐ Based on Buddhist methods mind training to reduce
obsessional doubt is generated inside the person without obsessions result from a reaction to, and avoidance of, an suffering. Suffering occurs when one lacks awareness of
mediation. The person rehearses obsessional doubt during intrusion or an ambivalent or uncertain state of affairs in automatic and distorted patterns. Mindfulness training
neutralization while being disconnected from the senses or reality. Avoidance prevents disconfirmation of the perceived teaches people to step out of automaticity and respond
authentic self that normally would invalidate the doubt. threat or dysfunctional appraisal in response to the intrusion. to difficulties with acceptance, equanimity and wisdom.
Primary hypothesized mechanisms of change
‐ The primary mechanism of change is modifying the ‐ The primary mechanism of change is the modification of ‐ Primary mechanisms of change are acceptance, openness
inferential confusion process that gives credibility to appraisals of significance of what otherwise would be usual, and flexibility through a non‐judgmental observer or meta‐
obsessional doubt. In turn, this allows for the resolution of unproblematic intrusions. In turn, this allows for the cognitive stance towards experience. This conscious and
obsessional doubt, its imagined consequences, distress and normalization of obsessions, reducing distress and the need detached stance attenuates distress and urge to engage in
compulsions. to engage in compulsive rituals. rituals as the obsessions become less salient and more
tolerable.
‐ Modification of feared‐self perceptions and self‐themes ‐ Modification of core beliefs and self‐schema underlying ‐ Developing a mindfulness stance facilitates building self‐
underlying obsessional narratives through the realization dysfunctional appraisals, including increasing self‐confidence compassion, kindness, self‐understanding and self‐trust.
that OCD represents a false self while repositioning the and awareness that symptoms inhibit the self by limiting
person back towards their authentic and real self social, leisure or work activities
‐ Reducing neutralization and avoidance leads to less doubt as ‐ Reducing neutralization and avoidance leads to cognitive ‐ Reducing neutralizations and avoidance facilitates full
these constitute rehearsing doubt and prevent the change as it normalizes anxiety while increasing the intensity engagement with painful experiences as they arise. Facing
assimilation of sense information that resolves the doubt. and frequency of obsessions without the occurrence of and exploring obsessions and distress consciously and with
Certainty already exists before the doubt, and therefore feared consequences. Obsessions are normal thoughts and detachment facilitates perspective taking, extinction of
neutralization and avoidance are unnecessary. neutralization and avoidance are unnecessary. habitual reactivity, and adaptive coping and behavior.
From: Aardema, F., Bouchard, S., Koszycki, D., Lavoie, M., Audet, J‐S, O’Connor, K. (forthcoming). Evaluation of inference‐based cognitive‐behavioral therapy for obsessive‐compulsive disorder: A multi‐center randomized
controlled trial with three treatment modalities. Psychotherapy and Psychosomatics.
OSM Table 2. Principal treatment targets and techniques in each active treatment (I-CBT, A-CBT and Mindfulness).
OSM Table 3C. Potential areas of overlap and distinctions (Mindfulness vs I-CBT)