5.neuro History

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The Nervous System

Symptoms

• Headache

• Disturbances of consciousness
1. Syncope
2. Seizures
3. Dizziness
4. Vertigo
Headache
• Primary or secondary
• Causes:
• SOCRATES to analyse it
Onset and course of headaches
Acute single episode

Subarachnoid haemorrhage Vasodilator drugs


Acute meningitis Angle-closure glaucoma

Acute recurrent

Migraine Angle-closure glaucoma


Sinusitis Cluster headache
Neuralgias (e.g. trigeminal and post-herpetic)

Subacute single episode

Infections (e.g. tuberculous meningitis, cerebral abscess)


Raised intracranial pressure (e.g. tumour, hydrocephalus)
Benign intracranial hypertension
Temporal arteritis
Onset and course of headaches

Chronic

Chronic daily headache syndrome


Depression
Cervical spondylosis
Drugs (e.g. nitrates, overuse of analgesics)
Migraine
• Is a primary headache disorder characterized by
recurrent headaches that are moderate to
severe. Typically, the headaches affect one half of the head,
are pulsating in nature, and last less than 24 hrs with
weeks to months symptoms free.

• Classified into classic (with aura) and common (without


aura).

• Precipitated by: bright light, loud noise, strong odors,


missed meals, intake of chocolate, cheese, citrus fruit,
travel, oral contraceptive pills.
Tension headache

• Bilateral

• 0ften frontal, temporal or occipital or 'like a


tight band‘ or “pressure over the head”.

• It is usually worse towards the end of the day.


Cluster headaches
• Attacks last 30-120 min
• 1-4 attacks within 24 hrs
• Clusters usually last weeks to months
• Awake the patient after 2-3 hours of falling
asleep
• Unilateral in the cheek, temple or around the
eye.
• Accompanied by ptosis, eye redness, eye
swelling and unilateral watering of the eye or
nose
Secondary Headache Syndromes

• Meningitis

• Subarachnoid haemorrhage

• Temporal arteritis ( usually more than 55


yrs with jaw pain , visual symptoms , and
tender temporal arteries).
Disturbances of consciousness
Syncope

• Alteration (or loss) of consciousness resulting


from a recoverable loss of adequate cerebral
blood flow.

• Mechanism:
Reduced cardiac output (Cardiac syncope) or
increased peripheral vasodilatation (Vasovagal
syncope) or combination of both.
Cardiac syncope

• May be provoked by exertion e.g. severe


aortic stenosis, HOCM.

• Or suddenly without warning when due to


cardiac arrhythmias.

• Recovery is usually rapid.


Vasovagal syncope

• Usually occurs whiles standing.


• Provoked by stimulation of the parasympathetic
system e.g. pain, emotional upset.
• More common in warm environments.
• Often preceded by light-headedness, vision
darkening, tinnitus, and nausea.
• It causes skin pallor.
• If kept flat, recovery is rapid.
Epileptic Seizures

• Definition: paroxysmal electrical


discharges from either the whole brain or
part of the brain

• Types:
1. Generalized
2. Focal (partial)
3. Focal with secondary generalization
Generalized tonic- clonic seizures pattern

Prodromal phase
Change of mood or 'odd' feeling (aura)
Tonic phase
Loss of consciousness Cyanosis
Spasm of all muscles Fall
Clonic phase
Jerking of limbs and trunk
Tongue biting
Incontinence of urine
Post-ictal phase
Flaccidity
Confusion
Headache
Amnesia
• Focal seizure:
Simple focal
Complex focal

Features of complex partial seizures

•Dream-like states
•Disturbances of memory (déjà-vu, jamais vu)
•Hallucinations of smell, taste or auditory
•Emotional disturbance
•Abnormal behavior
Vertigo (the illusion of movement)

Causes of vertigo

Central
•Migraine
•Brainstem ischemia or infarction
•Multiple sclerosis
Peripheral
•Méniére's disease (hearing loss , tinnitus , nausea and vomiting
•Benign paroxysmal positional vertigo
•Vestibular neuritis
•Trauma
•Drugs, e.g. gentamicin, anticonvulsants
Dizziness

May be due to:

1. Postural hypotension
2. Cerebrovascular disease/vertebra
basilar insuffeceincy
3. Arrhythmia
4. Hyperventilation
Stroke
Ischemic Stroke

Hemorrhagic Stroke

30
Territory of the cerebral vessels

Anterior Cerebral Artery


(light blue)

Middle Cerebral Artery

(pink)

Posterior Cerebral Artery

(light green)
Stroke Left Brain Stroke Right Brain
Middle Cerebral Artery (MCA) Occlusion
• Contralateral lower face weakness

• Contralateral hemiplegia

• Contralateral hemianesthesia

• Ataxia

• Speech impairments (usually the left brain)

• Perceptual deficits (usually the right brain)

• Visual deficits
Anterior Cerebral Artery
(ACA) Occlusion

• Weakness of foot and leg

• Sensory loss of foot and leg

• Ataxia

• Incontinence
Posterior Cerebral Artery
(PCA) Occlusion

• Midbrain syndrome (Weber’s


Syndrome) occlusion of
the paramedian branches of
the posterior cerebral artery
• Ipsilateral Third nerve palsy
• Contralateral hemiplegia

• Thalamic Syndromes
• Chorea or hemiballismus
• Hemisensory disturbances

• Visual field deficits (macular


sparing)

• Visual hallucinations

• Memory problems
The history
• Past history : important risk factors, e.g. other vascular
disease, hypertension.

• Family history (Some conditions have a variety of


inheritance patterns, e.g. Charcot–Marie–Tooth disease,
mitochondrial DNA abnormalities

• Drug history

• Social history :Alcohol is the most common neurological


toxin and damages both the CNS (ataxia, seizures,
cognitive symptoms) and the PNS (neuropathy). Poor diet
with vitamin deficiency

• Occupational history

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